JP2022522965A5 - - Google Patents

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Publication number
JP2022522965A5
JP2022522965A5 JP2021540811A JP2021540811A JP2022522965A5 JP 2022522965 A5 JP2022522965 A5 JP 2022522965A5 JP 2021540811 A JP2021540811 A JP 2021540811A JP 2021540811 A JP2021540811 A JP 2021540811A JP 2022522965 A5 JP2022522965 A5 JP 2022522965A5
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JP
Japan
Prior art keywords
sequence
labrisin
recombinant
amino acid
treatment
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JP2021540811A
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English (en)
Japanese (ja)
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JP7667569B2 (ja
JP2022522965A (ja
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Priority claimed from PCT/US2020/013752 external-priority patent/WO2020150396A1/en
Publication of JP2022522965A publication Critical patent/JP2022522965A/ja
Publication of JP2022522965A5 publication Critical patent/JP2022522965A5/ja
Application granted granted Critical
Publication of JP7667569B2 publication Critical patent/JP7667569B2/ja
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JP2021540811A 2019-01-15 2020-01-15 組換えラブリシン、並びにそれを使用するための組成物及び方法 Active JP7667569B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962792660P 2019-01-15 2019-01-15
US62/792,660 2019-01-15
PCT/US2020/013752 WO2020150396A1 (en) 2019-01-15 2020-01-15 Recombinant lubricins, and compositions and methods for using the same

Publications (3)

Publication Number Publication Date
JP2022522965A JP2022522965A (ja) 2022-04-21
JP2022522965A5 true JP2022522965A5 (https=) 2023-01-20
JP7667569B2 JP7667569B2 (ja) 2025-04-23

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ID=71614494

Family Applications (1)

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JP2021540811A Active JP7667569B2 (ja) 2019-01-15 2020-01-15 組換えラブリシン、並びにそれを使用するための組成物及び方法

Country Status (5)

Country Link
US (2) US20220127319A1 (https=)
EP (1) EP3911355A4 (https=)
JP (1) JP7667569B2 (https=)
CN (2) CN113573724B (https=)
WO (2) WO2020150390A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109735434B (zh) * 2016-09-14 2022-09-23 四川蓝光英诺生物科技股份有限公司 人工组织前体及制备其的方法
JP7667569B2 (ja) * 2019-01-15 2025-04-23 コーネル ユニバーシティー 組換えラブリシン、並びにそれを使用するための組成物及び方法
CN114107437A (zh) * 2021-11-30 2022-03-01 南通大学 一种基于荧光素酶亚基互补的主蛋白酶抑制剂活性检测系统及在药物筛选中的应用
CN115144303B (zh) * 2022-08-01 2025-05-16 中国科学院自动化研究所 基于磁粒子布朗弛豫的细胞质粘度检测方法及应用
CN117106024B (zh) * 2022-10-21 2024-05-24 南京市妇幼保健院 一种人血清多肽agdmp1及其在改善胰岛素抵抗中的应用
WO2025166171A1 (en) * 2024-01-31 2025-08-07 Cornell University Manufacturing and bioprocessing of multispecies biolubricants

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7309760B2 (en) * 2001-04-17 2007-12-18 The Board Of Trustees Of The University Of Arkansas Repeat sequences of the CA125 gene and their use for diagnostic and therapeutic interventions
CN1867350A (zh) 2003-08-14 2006-11-22 惠氏公司 重组润滑素分子及其用途
US20060173171A1 (en) * 2003-08-26 2006-08-03 Bamdad Cynthia C Techniques and compositions for diagnosis and treatment of cancer (muci)
CA2618791C (en) * 2005-08-12 2014-05-13 Riken Novel mucin-type glycoprotein and use thereof
WO2008133928A2 (en) * 2007-04-27 2008-11-06 The Gi Company, Inc. Mucin glycoproteins and their use for treatment of epithelial lesions and mucin dependent disorders
HUE024146T2 (en) 2008-05-07 2016-02-29 Univ California Medical filling and enrichment of eye surface lubrication
ES2634505T3 (es) * 2009-08-13 2017-09-28 Lubris Llc Tratamiento de PRG4 para la cistitis intersticial
US20140187474A1 (en) * 2011-02-16 2014-07-03 The Board Of Trustees Of The Leland Stanford Junior University Therapeutic use of mucin glycans
WO2013151665A2 (en) * 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of proteins associated with human disease
US20150010606A1 (en) * 2013-07-08 2015-01-08 Arthrex, Inc. Intra-articular injection and implant attachment of molecule consisting of lubricin and extracellular superoxide dismutase or hyaluronic acid and extracellular superoxide dismutase
US20180125926A1 (en) * 2013-09-25 2018-05-10 Axcella Health Inc. Compositions and Formulations and Methods of Production and Use Thereof
WO2015060935A1 (en) 2013-10-22 2015-04-30 Lubris, Llc Control of rheological properties of mixed hyaluronate/lubricin solutions
AU2014354859B2 (en) * 2013-11-26 2020-04-09 Lubris Llc Compositions and methods for inhibiting intercellular interactions
AU2016211694B2 (en) * 2015-01-26 2021-11-11 Lubris Llc Use of PRG4 as an anti-inflammatory agent
US20160280767A1 (en) * 2015-03-23 2016-09-29 Lonza Ltd. Methods for controlling protein glycosylation
WO2016187414A1 (en) * 2015-05-19 2016-11-24 Lubris Llc Use of prg4 to improve dynamic visual acuity and higher order aberrations
IL294183B2 (en) 2015-05-20 2023-10-01 Dana Farber Cancer Inst Inc shared neoantigens
RU2771490C2 (ru) * 2016-01-13 2022-05-05 Мериал, Инк. Рекомбинантные aav векторы, экспрессирующие остеопротективные гены, включая has2 и лубрицин, пригодные при лечении остеоартрита и сходных заболеваний суставов у млекопитающих
WO2017165674A1 (en) * 2016-03-23 2017-09-28 International Aids Vaccine Initiative Immunogenic trimers
AU2017290828A1 (en) * 2016-06-30 2019-01-24 Virogin Biotech Canada Ltd Pseudotyped oncolytic viral delivery of therapeutic polypeptides
CN109055426B (zh) * 2018-08-06 2021-06-25 智享生物(苏州)有限公司 一种在中华仓鼠卵巢细胞中表达生产类人润滑素的方法
JP7667569B2 (ja) * 2019-01-15 2025-04-23 コーネル ユニバーシティー 組換えラブリシン、並びにそれを使用するための組成物及び方法

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