JP2022520550A - 装飾された封入体及びその使用 - Google Patents

装飾された封入体及びその使用 Download PDF

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JP2022520550A
JP2022520550A JP2021546007A JP2021546007A JP2022520550A JP 2022520550 A JP2022520550 A JP 2022520550A JP 2021546007 A JP2021546007 A JP 2021546007A JP 2021546007 A JP2021546007 A JP 2021546007A JP 2022520550 A JP2022520550 A JP 2022520550A
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peptide
spytag
inclusion body
protein
partner
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JP2022520550A5 (enExample
Inventor
ライリンク ユーン
シモン ペートルス ヨング バウテル
バルト ファン デン ベルフ ファン サパルア ヘンドリク
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アベラ バイオサイエンス アクティエボラーグ
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Publication of JP2022520550A publication Critical patent/JP2022520550A/ja
Publication of JP2022520550A5 publication Critical patent/JP2022520550A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • C12N15/625DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/24Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/60Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2021546007A 2019-02-15 2020-02-14 装飾された封入体及びその使用 Pending JP2022520550A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19157490.4 2019-02-15
EP19157490 2019-02-15
PCT/EP2020/053933 WO2020165425A1 (en) 2019-02-15 2020-02-14 Decorated inclusion body and uses thereof

Publications (2)

Publication Number Publication Date
JP2022520550A true JP2022520550A (ja) 2022-03-31
JP2022520550A5 JP2022520550A5 (enExample) 2023-02-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021546007A Pending JP2022520550A (ja) 2019-02-15 2020-02-14 装飾された封入体及びその使用

Country Status (7)

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US (1) US20220064691A1 (enExample)
EP (1) EP3923968A1 (enExample)
JP (1) JP2022520550A (enExample)
CN (1) CN113347988A (enExample)
AU (1) AU2020220637A1 (enExample)
CA (1) CA3130159A1 (enExample)
WO (1) WO2020165425A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112062856A (zh) * 2020-09-16 2020-12-11 华侨大学 一种共价捕获目标蛋白的磁性载体制备方法
EP4408461A1 (en) * 2021-09-30 2024-08-07 AdaptVac ApS Methods and particles for modulating an immune response
CN117264081B (zh) * 2023-11-21 2025-03-21 华南理工大学 一种双肽受体激动剂及其制备方法与应用
CN117866110B (zh) * 2023-12-27 2024-06-11 广东唯泰生物科技有限公司 一种靶向flt-3的第四代嵌合抗原受体及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5578308A (en) 1990-02-12 1996-11-26 Capiau; Carine Glutaraldehyde and formalin detoxified bordetella toxin vaccine
GB201002362D0 (en) 2010-02-11 2010-03-31 Isis Innovation Peptide tag systems that spontaneously form an irreversible link to protein partners via isopeptide bonds
CN104884084B (zh) 2012-09-26 2018-05-22 Fvg有限公司 鱼用亚单位浸泡疫苗
WO2018138316A1 (en) 2017-01-27 2018-08-02 Abera Bioscience Ab New compositions, methods and uses
WO2018162450A1 (en) * 2017-03-06 2018-09-13 Fundación Para La Investigación Médica Aplicada New inmunostimulatory compositions comprising an entity of cold inducible rna-binding protein with an antigen for the activation of dendritic cells

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
J. CELL BIOL., vol. 213, no. 2, JPN6023009366, 2016, pages 147 - 149, ISSN: 0005012663 *
MOL IMAGING BIOL, vol. 18 (Suppl 2), JPN6023009365, 2016, pages 1260 - 2492300, ISSN: 0005124851 *
日本結晶学会誌, vol. 52, JPN6023009367, 2010, pages 20 - 24, ISSN: 0005012664 *

Also Published As

Publication number Publication date
AU2020220637A1 (en) 2021-10-07
US20220064691A1 (en) 2022-03-03
EP3923968A1 (en) 2021-12-22
CA3130159A1 (en) 2020-08-20
WO2020165425A1 (en) 2020-08-20
CN113347988A (zh) 2021-09-03

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