JP2022520442A5 - - Google Patents
Info
- Publication number
- JP2022520442A5 JP2022520442A5 JP2021547429A JP2021547429A JP2022520442A5 JP 2022520442 A5 JP2022520442 A5 JP 2022520442A5 JP 2021547429 A JP2021547429 A JP 2021547429A JP 2021547429 A JP2021547429 A JP 2021547429A JP 2022520442 A5 JP2022520442 A5 JP 2022520442A5
- Authority
- JP
- Japan
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962806201P | 2019-02-15 | 2019-02-15 | |
| US62/806,201 | 2019-02-15 | ||
| US201962931877P | 2019-11-07 | 2019-11-07 | |
| US62/931,877 | 2019-11-07 | ||
| PCT/IB2020/051100 WO2020165776A1 (en) | 2019-02-15 | 2020-02-11 | Hydroxypyridoxazepines as nrf2 activators |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022520442A JP2022520442A (ja) | 2022-03-30 |
| JPWO2020165776A5 JPWO2020165776A5 (https=) | 2023-02-21 |
| JP2022520442A5 true JP2022520442A5 (https=) | 2023-02-21 |
| JP7602469B2 JP7602469B2 (ja) | 2024-12-18 |
Family
ID=69726636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021547429A Active JP7602469B2 (ja) | 2019-02-15 | 2020-02-11 | Ｎｒｆ２活性剤としてのヒドロキシピリドキシアゼピン |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US11945826B2 (https=) |
| EP (1) | EP3924356A1 (https=) |
| JP (1) | JP7602469B2 (https=) |
| KR (1) | KR102932313B1 (https=) |
| CN (2) | CN113474349B (https=) |
| AU (1) | AU2020222080C1 (https=) |
| BR (1) | BR112021016042A2 (https=) |
| CA (1) | CA3129955A1 (https=) |
| CL (1) | CL2021002110A1 (https=) |
| CO (1) | CO2021010930A2 (https=) |
| IL (2) | IL313950A (https=) |
| MA (1) | MA54939A (https=) |
| MX (1) | MX2021009659A (https=) |
| MY (1) | MY209603A (https=) |
| PH (1) | PH12021551873A1 (https=) |
| SG (1) | SG11202108257TA (https=) |
| TW (2) | TWI843806B (https=) |
| WO (1) | WO2020165776A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3833662B1 (en) | 2018-08-20 | 2024-01-17 | Janssen Pharmaceutica NV | Inhibitors of keap1-nrf2 protein-protein interaction |
| AR118050A1 (es) | 2019-02-15 | 2021-09-15 | Bristol Myers Squibb Co | Compuestos bicíclicos sustituidos como moduladores del receptor farnesoide x |
| KR102932313B1 (ko) * | 2019-02-15 | 2026-02-26 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | Nrf2 활성화제로서 히드록시피리드옥사제핀 |
| AU2020283361B2 (en) * | 2019-05-31 | 2025-11-27 | Ube Corporation | Benzotriazole derivative |
| CN118488944A (zh) | 2022-01-07 | 2024-08-13 | 中外制药株式会社 | 具有Nrf2活化作用的含氮杂环化合物 |
| US20250282724A1 (en) | 2022-04-28 | 2025-09-11 | Daiichi Sankyo Company, Limited | Benzotriazole compound |
| JPWO2023210740A1 (https=) | 2022-04-28 | 2023-11-02 | ||
| EP4580612A1 (en) * | 2022-09-02 | 2025-07-09 | Institut National de la Santé et de la Recherche Médicale | Use of nrf2 activators for the treatment of cerebral small vessel disease |
| CN121152792A (zh) | 2023-06-19 | 2025-12-16 | 中外制药株式会社 | 具有Nrf2活化作用的含氮杂环化合物的晶体 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7714012B2 (en) * | 2006-11-17 | 2010-05-11 | Trustees Of Dartmouth University | Synthesis and biological activities of new tricyclic-bis-enones (TBEs) |
| US9056850B2 (en) * | 2008-10-17 | 2015-06-16 | Janssen Pharmaceutica N.V. | Process for the preparation of compounds useful as inhibitors of SGLT |
| CN104418834B (zh) * | 2013-08-23 | 2017-09-15 | 重庆博腾制药科技股份有限公司 | 一种抗糖尿病药物中间体的合成方法 |
| SG11201604611SA (en) | 2013-12-18 | 2016-07-28 | Glaxosmithkline Ip Dev Ltd | Nrf2 regulators |
| CN105272960A (zh) * | 2014-07-18 | 2016-01-27 | 上海科胜药物研发有限公司 | 一种坎格列净中间体2-(2-甲基-5-溴苄基)-5-(4-氟苯)噻吩的制备方法 |
| WO2016178148A1 (en) * | 2015-05-05 | 2016-11-10 | Glenmark Pharmaceuticals Limited | Process for preparation of dapagliflozin |
| CA2988373A1 (en) | 2015-06-15 | 2016-12-22 | Glaxosmithkline Intellectual Property Development Limited | Nrf2 regulators |
| WO2016203401A1 (en) | 2015-06-15 | 2016-12-22 | Glaxosmithkline Intellectual Property Development Limited | Nrf2 regulators |
| LT3307739T (lt) | 2015-06-15 | 2021-03-10 | Glaxosmithkline Intellectual Property Development Limited | Nrf2 reguliatoriai |
| US10201531B2 (en) * | 2015-08-12 | 2019-02-12 | Mochida Pharmaceutical Co., Ltd. | Indazolyl-oxo-isothiazole compounds |
| US10364256B2 (en) * | 2015-10-06 | 2019-07-30 | Glaxosmithkline Intellectual Property Development Limited | Biaryl pyrazoles as NRF2 regulators |
| US10913762B2 (en) * | 2016-01-27 | 2021-02-09 | Msn Laboratories Private Limited | Process for the preparation of D-glucitol, 1,5-anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl] oxy]phenyl] methyl] phenyl]-, (1S) and its crystalline forms thereof |
| CN108779108A (zh) * | 2016-12-06 | 2018-11-09 | 葛兰素史密斯克莱知识产权发展有限公司 | 3-(2,3-二氢-1h-茚-5-基)丙酸衍生物和它们作为nrf2调节剂的用途 |
| JP2020500918A (ja) * | 2016-12-12 | 2020-01-16 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ | Ｎｒｆ２レギュレーターとしてのｎ−アリールピラゾール |
| ES2901617T3 (es) * | 2016-12-14 | 2022-03-23 | Glaxosmithkline Ip Dev Ltd | Bisarilamidas como reguladores de NRF2 |
| CA3044773A1 (en) * | 2016-12-15 | 2018-06-21 | Glaxosmithkline Intellectual Property Development Limited | Nrf2 activators |
| KR102932313B1 (ko) * | 2019-02-15 | 2026-02-26 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | Nrf2 활성화제로서 히드록시피리드옥사제핀 |
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2020
- 2020-02-11 KR KR1020217029193A patent/KR102932313B1/ko active Active
- 2020-02-11 BR BR112021016042-6A patent/BR112021016042A2/pt unknown
- 2020-02-11 JP JP2021547429A patent/JP7602469B2/ja active Active
- 2020-02-11 CA CA3129955A patent/CA3129955A1/en active Pending
- 2020-02-11 EP EP20708180.3A patent/EP3924356A1/en active Pending
- 2020-02-11 AU AU2020222080A patent/AU2020222080C1/en active Active
- 2020-02-11 IL IL313950A patent/IL313950A/en unknown
- 2020-02-11 MA MA054939A patent/MA54939A/fr unknown
- 2020-02-11 US US17/429,088 patent/US11945826B2/en active Active
- 2020-02-11 SG SG11202108257TA patent/SG11202108257TA/en unknown
- 2020-02-11 PH PH1/2021/551873A patent/PH12021551873A1/en unknown
- 2020-02-11 CN CN202080014726.4A patent/CN113474349B/zh active Active
- 2020-02-11 CN CN202410206971.5A patent/CN118206566A/zh active Pending
- 2020-02-11 IL IL285438A patent/IL285438B2/en unknown
- 2020-02-11 WO PCT/IB2020/051100 patent/WO2020165776A1/en not_active Ceased
- 2020-02-11 MX MX2021009659A patent/MX2021009659A/es unknown
- 2020-02-11 MY MYPI2021004562A patent/MY209603A/en unknown
- 2020-02-13 TW TW109104455A patent/TWI843806B/zh active
- 2020-02-13 TW TW113112455A patent/TWI880702B/zh active
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2021
- 2021-08-11 CL CL2021002110A patent/CL2021002110A1/es unknown
- 2021-08-19 CO CONC2021/0010930A patent/CO2021010930A2/es unknown
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2024
- 2024-02-27 US US18/588,051 patent/US20240352034A1/en not_active Abandoned
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2025
- 2025-02-14 US US19/054,254 patent/US20250313573A1/en active Pending