JP2022518235A - 進行期固形腫瘍がんの治療用rna - Google Patents

進行期固形腫瘍がんの治療用rna Download PDF

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JP2022518235A
JP2022518235A JP2021541606A JP2021541606A JP2022518235A JP 2022518235 A JP2022518235 A JP 2022518235A JP 2021541606 A JP2021541606 A JP 2021541606A JP 2021541606 A JP2021541606 A JP 2021541606A JP 2022518235 A JP2022518235 A JP 2022518235A
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rna
cancer
tumor
seq
therapy
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JP2022518235A5 (https=
Inventor
ティモシー・アール・ヴァヘナール
セレナ・マシャリ
セムラ・ヨルク
カール・スー
ニコラス・アクアヴェラ
マリエ・ベルナルド
ローベルト・ヤブロウスキー
ウグア・シャヒン
フリーデリーケ・ギーゼケ
ズザナ・ジラコヴァ・トルンコヴァ
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Sanofi SA
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    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7115Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
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    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
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JP2021541606A 2019-01-21 2020-01-17 進行期固形腫瘍がんの治療用rna Ceased JP2022518235A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962794889P 2019-01-21 2019-01-21
US62/794,889 2019-01-21
US201962926384P 2019-10-25 2019-10-25
US62/926,384 2019-10-25
EP19306461.5 2019-11-12
EP19306461 2019-11-12
PCT/US2020/014019 WO2020154187A1 (en) 2019-01-21 2020-01-17 Therapeutic rna for advanced stage solid tumor cancers

Publications (2)

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JP2022518235A true JP2022518235A (ja) 2022-03-14
JP2022518235A5 JP2022518235A5 (https=) 2023-02-07

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JP2021541606A Ceased JP2022518235A (ja) 2019-01-21 2020-01-17 進行期固形腫瘍がんの治療用rna

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US (1) US20220040218A1 (https=)
EP (1) EP3914354A1 (https=)
JP (1) JP2022518235A (https=)
KR (1) KR20210119451A (https=)
CN (1) CN113557060A (https=)
AU (1) AU2020211584A1 (https=)
BR (1) BR112021013887A2 (https=)
CA (1) CA3125773A1 (https=)
IL (1) IL284646A (https=)
MX (1) MX2021008604A (https=)
SG (1) SG11202107395VA (https=)
TW (1) TW202043273A (https=)
WO (1) WO2020154187A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022518236A (ja) * 2019-01-21 2022-03-14 サノフイ 進行期固形腫瘍がんに対する治療用rnaおよび抗pd1抗体

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202428301A (zh) 2017-02-28 2024-07-16 法商賽諾菲公司 治療性rna
US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018160540A1 (en) * 2017-02-28 2018-09-07 Sanofi Therapeutic rna

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1867581B (zh) * 2003-10-10 2012-02-01 诺沃挪第克公司 Il-21衍生物
WO2016005004A1 (en) 2014-07-11 2016-01-14 Biontech Rna Pharmaceuticals Gmbh Stabilization of poly(a) sequence encoding dna sequences
TWI910495B (zh) * 2016-05-13 2026-01-01 美商再生元醫藥公司 藉由投予pd-1抑制劑治療皮膚癌之方法
MA47604A (fr) * 2017-02-21 2020-01-01 Regeneron Pharma Anticorps anti-pd-1 pour le traitement du cancer du poumon
WO2020041655A1 (en) * 2018-08-24 2020-02-27 Sanofi Therapeutic rna for solid tumor cancers
AU2020210614A1 (en) * 2019-01-21 2021-08-26 Sanofi Therapeutic RNA and anti-PD1 antibodies for advanced stage solid tumor cancers
JP7774006B2 (ja) * 2020-06-22 2025-11-20 イミュナミ ラボラトリーズ プライベート リミティド 癌治療における使用のための組換えポリペプチド及び組合せ
CN117043193A (zh) * 2021-02-11 2023-11-10 瑞泽恩制药公司 通过施用新辅助pd-1抑制剂治疗癌症的方法
US20250032611A1 (en) * 2021-11-12 2025-01-30 The Brigham And Women's Hospital, Inc. Gene editing and engineering stem cells for drug delivery

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018160540A1 (en) * 2017-02-28 2018-09-07 Sanofi Therapeutic rna

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022518236A (ja) * 2019-01-21 2022-03-14 サノフイ 進行期固形腫瘍がんに対する治療用rnaおよび抗pd1抗体

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SG11202107395VA (en) 2021-08-30
EP3914354A1 (en) 2021-12-01
US20220040218A1 (en) 2022-02-10
TW202043273A (zh) 2020-12-01
KR20210119451A (ko) 2021-10-05
AU2020211584A1 (en) 2021-08-26
BR112021013887A2 (pt) 2021-09-21
WO2020154187A1 (en) 2020-07-30
IL284646A (en) 2021-08-31
CA3125773A1 (en) 2020-07-30
MX2021008604A (es) 2021-10-26
CN113557060A (zh) 2021-10-26

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