JP2022518089A5 - - Google Patents

Info

Publication number
JP2022518089A5
JP2022518089A5 JP2021517833A JP2021517833A JP2022518089A5 JP 2022518089 A5 JP2022518089 A5 JP 2022518089A5 JP 2021517833 A JP2021517833 A JP 2021517833A JP 2021517833 A JP2021517833 A JP 2021517833A JP 2022518089 A5 JP2022518089 A5 JP 2022518089A5
Authority
JP
Japan
Prior art keywords
flow cytometry
screening
optimized
titer
target
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021517833A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022518089A (ja
JP7384905B2 (ja
Filing date
Publication date
Priority claimed from US16/253,060 external-priority patent/US11137337B2/en
Application filed filed Critical
Publication of JP2022518089A publication Critical patent/JP2022518089A/ja
Publication of JP2022518089A5 publication Critical patent/JP2022518089A5/ja
Application granted granted Critical
Publication of JP7384905B2 publication Critical patent/JP7384905B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021517833A 2019-01-21 2020-01-14 フローサイトメトリー調査のための流体サンプルの最適化された希釈のためのデータ分析を伴うフローサイトメトリー Active JP7384905B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/253,060 US11137337B2 (en) 2019-01-21 2019-01-21 Flow cytometry with data analysis for optimized dilution of fluid samples for flow cytometry investigation
US16/253,060 2019-01-21
PCT/US2020/013549 WO2020154135A1 (en) 2019-01-21 2020-01-14 Flow cytometry with data analysis for optimized dilution of fluid samples for flow cytometry investigation

Publications (3)

Publication Number Publication Date
JP2022518089A JP2022518089A (ja) 2022-03-14
JP2022518089A5 true JP2022518089A5 (https=) 2023-01-25
JP7384905B2 JP7384905B2 (ja) 2023-11-21

Family

ID=69469253

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021517833A Active JP7384905B2 (ja) 2019-01-21 2020-01-14 フローサイトメトリー調査のための流体サンプルの最適化された希釈のためのデータ分析を伴うフローサイトメトリー

Country Status (6)

Country Link
US (1) US11137337B2 (https=)
EP (1) EP3914896B1 (https=)
JP (1) JP7384905B2 (https=)
CN (1) CN113167716B (https=)
ES (1) ES2992682T3 (https=)
WO (1) WO2020154135A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107615065B (zh) 2015-03-23 2020-07-24 以埃森生物科学股份有限公司的名义经营的埃森仪器股份有限公司 对生物材料评估腺病毒或腺相关病毒的病毒类型的非缔合的病毒尺寸颗粒
WO2020028639A1 (en) 2018-08-01 2020-02-06 Essen Instruments, Inc. D/B/A Essen Bioscience, Inc. Methods, kits and stain compositions for flow cytometry evaluation of unassociated virus-size particles using multiple fluorogenic dyes
EP3948279B1 (en) 2019-03-26 2025-06-18 Sartorius BioAnalytical Instruments, Inc. Flow cytometry evaluation for unassociated non-enveloped viral particles
US11520775B2 (en) * 2020-01-24 2022-12-06 Sartorius Bioanalytical Instruments, Inc. Adaptive data sub-sampling and computation
US11709116B2 (en) 2020-02-04 2023-07-25 Sartorius Bioanalytical Instruments, Inc. Liquid flourescent dye concentrate for flow cytometry evaluation of virus-size particles and related products and methods
KR20240148421A (ko) * 2022-02-14 2024-10-11 벡톤 디킨슨 앤드 컴퍼니 그룹별 유세포 분석 데이터를 위한 그래픽 사용자 인터페이스 및 이를 사용하는 방법

Family Cites Families (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857451A (en) 1984-12-24 1989-08-15 Flow Cytometry Standards Corporation Method of compensating and calibrating a flow cytometer, and microbead standards kit therefor
US5245318A (en) 1987-07-24 1993-09-14 Canon Kabushiki Kaisha Particle analyzing apparatus having pressure control system
US5040890A (en) 1987-11-25 1991-08-20 Becton, Dickinson And Company Sheathed particle flow controlled by differential pressure
DK111990D0 (da) 1990-05-04 1990-05-04 Biometic Aps Apparat og fremgangsmaade til analyse af en vaeskesuspension
US5525302A (en) 1991-02-01 1996-06-11 Astle; Thomas W. Method and device for simultaneously transferring plural samples
JP3075367B2 (ja) 1991-04-05 2000-08-14 シスメックス株式会社 粒子分析方法及び装置
JP3115641B2 (ja) * 1991-04-24 2000-12-11 シスメックス株式会社 粒子計数方法
US5395588A (en) 1992-12-14 1995-03-07 Becton Dickinson And Company Control of flow cytometer having vacuum fluidics
JP3052665B2 (ja) 1993-01-26 2000-06-19 株式会社日立製作所 フローセル装置
US5306467A (en) 1993-02-17 1994-04-26 Hamilton-Thorn Research Apparatus for measurement of cell concentration in a biological sample employing a magnetic slide loading apparatus
US5483469A (en) 1993-08-02 1996-01-09 The Regents Of The University Of California Multiple sort flow cytometer
US5602039A (en) 1994-10-14 1997-02-11 The University Of Washington Flow cytometer jet monitor system
EP0822404B1 (en) 1996-07-30 2009-06-17 Siemens Healthcare Diagnostics Inc. Optical system for a hematology analytical instrument
DK0925494T3 (da) 1996-09-04 2002-07-01 Scandinavian Micro Biodevices Mikrostrømningssystem til partikelseparation og analyse
US6183697B1 (en) 1997-05-27 2001-02-06 Sysmex Corporation Particle measuring apparatus
US5895764A (en) 1997-11-24 1999-04-20 University Of New Mexico Controlled sheath flow injection cytometry
US6248590B1 (en) 1998-02-27 2001-06-19 Cytomation, Inc. Method and apparatus for flow cytometry
JP4215397B2 (ja) 1998-05-14 2009-01-28 ルミネックス コーポレイション 多重分析物診断システム
US6110427A (en) 1998-08-14 2000-08-29 Becton, Dickinson And Company Flow regulator to maintain controllable volumetric flow rate
EP1144958B1 (de) 1998-12-22 2004-03-24 Sensirion AG Verfahren und sensor zur messung eines massenflusses
US6256096B1 (en) 1999-01-11 2001-07-03 Softray Flow cytometry apparatus and method
US6890487B1 (en) 1999-09-30 2005-05-10 Science & Technology Corporation ©UNM Flow cytometry for high throughput screening
US7024316B1 (en) 1999-10-21 2006-04-04 Dakocytomation Colorado, Inc. Transiently dynamic flow cytometer analysis system
WO2001084087A1 (de) 2000-05-04 2001-11-08 Sensirion Ag Flusssensor für flüssigkeiten
FR2808804B1 (fr) 2000-05-09 2002-08-02 Nautilus Biotech Procede de determination du titre d'agents biologiques en temps reel dans des cellules cibles vivantes et ses applications
US7630063B2 (en) 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
US7471394B2 (en) 2000-08-02 2008-12-30 Honeywell International Inc. Optical detection system with polarizing beamsplitter
US7420659B1 (en) 2000-06-02 2008-09-02 Honeywell Interantional Inc. Flow control system of a cartridge
US6597438B1 (en) 2000-08-02 2003-07-22 Honeywell International Inc. Portable flow cytometry
US7978329B2 (en) 2000-08-02 2011-07-12 Honeywell International Inc. Portable scattering and fluorescence cytometer
US7016022B2 (en) 2000-08-02 2006-03-21 Honeywell International Inc. Dual use detectors for flow cytometry
US8071051B2 (en) 2004-05-14 2011-12-06 Honeywell International Inc. Portable sample analyzer cartridge
US20020026822A1 (en) 2000-07-26 2002-03-07 Reading Andrew R. Vehicle gas emission sampling and analysis assembly
US7061595B2 (en) 2000-08-02 2006-06-13 Honeywell International Inc. Miniaturized flow controller with closed loop regulation
US7277166B2 (en) 2000-08-02 2007-10-02 Honeywell International Inc. Cytometer analysis cartridge optical configuration
EP1466162A1 (en) 2002-01-10 2004-10-13 Board Of Regents The University Of Texas System Flow sorting system and methods regarding same
GB2388189B (en) 2002-04-29 2006-01-11 Robert Jeffrey Geddes Carr Optical detection and analysis of particles
US6880414B2 (en) 2002-08-08 2005-04-19 Becton Dickinson And Company Sort block and liquid collection device for sorting flow cytometer
US7428971B2 (en) 2002-11-01 2008-09-30 Techno Network Shikoku Co., Ltd. Method for sorting and recovering fine particle and apparatus for recovery
BRPI0408857B1 (pt) 2003-03-28 2018-09-11 Inguran Llc aparelho, métodos e processos para separar partículas e para prover esperma de animal separado por sexo
US7069191B1 (en) 2003-08-06 2006-06-27 Luminex Corporation Methods for reducing the susceptibility of a peak search to signal noise
KR101135138B1 (ko) 2003-08-13 2012-04-16 루미넥스 코포레이션 유세포 분석기식 측정 시스템의 하나 이상의 파라미터의제어 방법
US20080021674A1 (en) 2003-09-30 2008-01-24 Robert Puskas Methods for Enhancing the Analysis of Particle Detection
US7256891B2 (en) 2004-08-23 2007-08-14 Beckman Coulter, Inc. Sensor alignment apparatus for an analysis system
US7491502B2 (en) 2004-12-17 2009-02-17 The General Hospital Corporation In vivo flow cytometry system and method
US7355696B2 (en) 2005-02-01 2008-04-08 Arryx, Inc Method and apparatus for sorting cells
FR2883970B1 (fr) 2005-03-31 2007-11-16 C2 Diagnostics Sa Dispositif hydraulique pour appareil d'analyse sanguine, procede associe et appareil d'analyse equipe d'un tel dispositif
US7307721B2 (en) 2005-04-13 2007-12-11 Brightwell Technologies Particle imaging system with a varying flow rate
EP1875200A1 (en) 2005-04-29 2008-01-09 Honeywell International Inc. Cytometer cell counting and size measurement method
JP4995197B2 (ja) 2005-07-01 2012-08-08 ハネウェル・インターナショナル・インコーポレーテッド 3d流体力学的集束を有する成形カートリッジ
US8017402B2 (en) 2006-03-08 2011-09-13 Accuri Cytometers, Inc. Fluidic system for a flow cytometer
US7776268B2 (en) 2005-10-13 2010-08-17 Accuri Cytometers, Inc. User interface for a fluidic system of a flow cytometer
US8303894B2 (en) 2005-10-13 2012-11-06 Accuri Cytometers, Inc. Detection and fluidic system of a flow cytometer
US7485153B2 (en) 2005-12-27 2009-02-03 Honeywell International Inc. Fluid free interface for a fluidic analyzer
US8182767B2 (en) 2005-12-27 2012-05-22 Honeywell International Inc. Needle-septum interface for a fluidic analyzer
JP5431732B2 (ja) 2005-12-29 2014-03-05 ハネウェル・インターナショナル・インコーポレーテッド マイクロ流体フォーマットにおけるアッセイ実装
US7780916B2 (en) 2006-03-08 2010-08-24 Accuri Cytometers, Inc. Flow cytometer system with unclogging feature
US8283177B2 (en) 2006-03-08 2012-10-09 Accuri Cytometers, Inc. Fluidic system with washing capabilities for a flow cytometer
US7981661B2 (en) 2006-04-17 2011-07-19 Accuri Cytometers, Inc. Flow cytometer system with sheath and waste fluid measurement
US20090105963A1 (en) 2006-05-13 2009-04-23 Jesper Laursen Methods for Flow Cytometry Analyses of Un-Lysed Cells from Biological Fluids
US9810707B2 (en) * 2006-05-17 2017-11-07 Luminex Corporation Chip-based flow cytometer type systems for analyzing fluorescently tagged particles
WO2008010120A2 (en) 2006-07-17 2008-01-24 Koninklijke Philips Electronics N.V. Employing beam scanning for optical detection
WO2008041900A1 (en) 2006-10-06 2008-04-10 Boule Medical Ab Device for extraction of a partial defined sample volume from a lager volume, method for operating the device, set of at least two devices, method of operation the set, an analytical instrument connectable to the device, method for operating the instrument, a system, and a method for operating the system
US8715573B2 (en) 2006-10-13 2014-05-06 Accuri Cytometers, Inc. Fluidic system for a flow cytometer with temporal processing
US7605919B2 (en) 2006-10-30 2009-10-20 Brightwell Technologies Inc. Method and apparatus for analyzing particles in a fluid
US8202733B1 (en) 2006-12-18 2012-06-19 Shervin Javadi System and method for obtaining a differential flow rate
US20110024615A1 (en) 2006-12-29 2011-02-03 Tanner Scott D Cell injector for flow cytometer having mass spectrometer detector and method for using same
US7817276B2 (en) 2007-02-05 2010-10-19 Palo Alto Research Center Incorporated Distinguishing objects
EP2664916B1 (en) 2007-04-02 2017-02-08 Acoustic Cytometry Systems, Inc. Method for manipulating a fluid medium within a flow cell using acoustic focusing
US7691636B2 (en) 2007-05-23 2010-04-06 Beckman Coulter, Inc. Method and apparatus for compensating for variations in particle trajectories in electrostatic sorter for flowcell cytometer
GB0801375D0 (en) 2008-01-25 2008-03-05 Secr Defence Fluid-borne particle detector
US8263955B2 (en) 2008-12-18 2012-09-11 Palo Alto Research Center Incorporated Causing relative motion
WO2010114858A1 (en) 2009-03-30 2010-10-07 Trustees Of Boston University Reservoir-buffered mixers and remote valve switching for microfluidic devices
US8599383B2 (en) 2009-05-06 2013-12-03 The Regents Of The University Of California Optical cytometry
WO2010132053A1 (en) 2009-05-13 2010-11-18 Indevr, Inc. Flow measurement and control for improved quantification of particles in flow cytometry
JP5304456B2 (ja) 2009-06-10 2013-10-02 ソニー株式会社 微小粒子測定装置
US8188438B2 (en) 2009-10-20 2012-05-29 Diagnostics Chips, LLC Electrokinetic microfluidic flow cytometer apparatuses with differential resistive particle counting and optical sorting
US9551600B2 (en) 2010-06-14 2017-01-24 Accuri Cytometers, Inc. System and method for creating a flow cytometer network
US20120225475A1 (en) 2010-11-16 2012-09-06 1087 Systems, Inc. Cytometry system with quantum cascade laser source, acoustic detector, and micro-fluidic cell handling system configured for inspection of individual cells
US8761486B2 (en) 2011-02-22 2014-06-24 Bio-Rad Laboratories, Inc. Line scan cytometry systems and methods
JP5904996B2 (ja) 2011-03-29 2016-04-20 オリンパス株式会社 単一発光粒子検出を用いた光分析装置、光分析方法並びに光分析用コンピュータプログラム
JP5712396B2 (ja) 2012-03-30 2015-05-07 公益財団法人神奈川科学技術アカデミー イメージングセルソーター
US8735853B2 (en) 2012-06-09 2014-05-27 E.I. Spectra, Llc Fluorescence flow cytometry
CN110579435B (zh) 2012-10-15 2023-09-26 纳诺赛莱克特生物医药股份有限公司 颗粒分选的系统、设备和方法
CA2796489C (en) 2012-11-22 2019-08-27 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Man-portable device for detecting hazardous material
CA2912925A1 (en) 2013-06-28 2014-12-31 Virocyt, Inc. Processing biological material for flow cytometry evaluation for virus particles
US9880085B2 (en) 2014-03-21 2018-01-30 Intellicyt Corporation Flow cytometer system including flow cytometer, autosampler and system integration structure
EP3152547A4 (en) 2014-06-05 2017-05-17 IntelliCyt Corporation Automated alignment of optics within a flow cytometer
US9903803B2 (en) 2014-06-05 2018-02-27 Intellicyt Corporation Flow cytometer signal peak identification employing dynamic thresholding
EP3152545A2 (en) 2014-06-05 2017-04-12 IntelliCyt Corporation Flow cytometer with optical system assembly
WO2016048872A1 (en) 2014-09-23 2016-03-31 Neostem Oncology, Llc Compositions, methods and kits used to determine potency of dendritic cells in cancer immunitherpay
CN107615065B (zh) 2015-03-23 2020-07-24 以埃森生物科学股份有限公司的名义经营的埃森仪器股份有限公司 对生物材料评估腺病毒或腺相关病毒的病毒类型的非缔合的病毒尺寸颗粒
WO2017019404A1 (en) 2015-07-24 2017-02-02 Merial, Inc. High throughput methods for virus quantification
CN107063976B (zh) 2017-03-30 2020-04-10 中国农业科学院特产研究所 一种半数细胞培养物感染量的计算系统及方法
JP7005176B2 (ja) 2017-05-31 2022-01-21 シスメックス株式会社 試料調製装置、試料調製システム、試料調製方法及び粒子分析装置

Similar Documents

Publication Publication Date Title
JP2022518089A5 (https=)
Welsh et al. Small particle fluorescence and light scatter calibration using FCMPASS software
TWI699732B (zh) 用於缺陷分類之方法及系統
Chiang et al. Understanding the ramifications of quantitative ordinal scales on accuracy of estimates of disease severity and data analysis in plant pathology
JP6437522B2 (ja) フローサイトメトリーにおけるパネル設計のためのシステム及び方法
RU2640568C2 (ru) Способы и системы для оценки риска рака желудочно-кишечного тракта
US20180211000A1 (en) Method and System for Genotyping Samples in a Normalized Allelic Space
US8605971B2 (en) Method and system for determining an optimal dilution of a reagent
JP7384905B2 (ja) フローサイトメトリー調査のための流体サンプルの最適化された希釈のためのデータ分析を伴うフローサイトメトリー
JP2016528506A (ja) 分類を支援するための分析法
CN103959292A (zh) 用于近红外光谱分析的化学计量
Gracia Tello et al. Capi-score: a quantitative algorithm for identifying disease patterns in nailfold videocapillaroscopy
US20090226916A1 (en) Automated Analysis of DNA Samples
JP7482222B2 (ja) 発光分光分析による元素識別方法及びシステム
US20080077351A1 (en) Calibration curve fit method and apparatus
Jang et al. Towards a biomarker for acute arterial thrombosis using complete blood count and white blood cell differential parameters in mice
JP2024507652A5 (https=)
JP2009534663A (ja) テンプレートを使用する細胞分析結果のデータの表示
WO2017115775A1 (ja) 分析装置、分析方法、および、分析システム
CN104569368B (zh) 生物样本分析系统和方法
US20110167029A1 (en) Method and device for classifying, displaying and exploring biological data
Hernández-Suárez et al. Probability models for detecting transgenic plants
US10973467B2 (en) Method and system for automated diagnostics of none-infectious illnesses
Park et al. Verification of reproducibility of VCS2000 equipment for mechanical measurement of Korean Landrace× Yorkshire (F1), F1× Duroc (LYD) pig carcasses
Del Ponte et al. Meta-analysis in plant pathology: publication patterns, methodological trends, and potential future directions