JP2022517988A5 - - Google Patents
Info
- Publication number
- JP2022517988A5 JP2022517988A5 JP2021540305A JP2021540305A JP2022517988A5 JP 2022517988 A5 JP2022517988 A5 JP 2022517988A5 JP 2021540305 A JP2021540305 A JP 2021540305A JP 2021540305 A JP2021540305 A JP 2021540305A JP 2022517988 A5 JP2022517988 A5 JP 2022517988A5
- Authority
- JP
- Japan
- Prior art keywords
- zfp
- composition according
- polynucleotides
- striatum
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962792701P | 2019-01-15 | 2019-01-15 | |
| US62/792,701 | 2019-01-15 | ||
| PCT/US2020/013661 WO2020150338A1 (en) | 2019-01-15 | 2020-01-15 | Htt repressors and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022517988A JP2022517988A (ja) | 2022-03-11 |
| JP2022517988A5 true JP2022517988A5 (https=) | 2023-01-25 |
| JP7542912B2 JP7542912B2 (ja) | 2024-09-02 |
Family
ID=71614037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021540305A Active JP7542912B2 (ja) | 2019-01-15 | 2020-01-15 | Ｈｔｔリプレッサーおよびその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220064237A1 (https=) |
| EP (1) | EP3911349A4 (https=) |
| JP (1) | JP7542912B2 (https=) |
| CN (1) | CN113301909B (https=) |
| WO (1) | WO2020150338A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11421007B2 (en) | 2018-04-18 | 2022-08-23 | Sangamo Therapeutics, Inc. | Zinc finger protein compositions for modulation of huntingtin (Htt) |
| CN115487315B (zh) * | 2022-04-20 | 2023-08-04 | 暨南大学 | 治疗亨廷顿病的药物 |
| CN121729237A (zh) * | 2023-06-30 | 2026-03-24 | 武田药品工业株式会社 | Htt阻遏物及其用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7888121B2 (en) * | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| US7972854B2 (en) * | 2004-02-05 | 2011-07-05 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| EP2027262B1 (en) * | 2006-05-25 | 2010-03-31 | Sangamo Biosciences Inc. | Variant foki cleavage half-domains |
| CA2769262C (en) * | 2009-07-28 | 2019-04-30 | Sangamo Biosciences, Inc. | Methods and compositions for treating trinucleotide repeat disorders |
| WO2013130824A1 (en) | 2012-02-29 | 2013-09-06 | Sangamo Biosciences, Inc. | Methods and compositions for treating huntington's disease |
| WO2015070212A1 (en) * | 2013-11-11 | 2015-05-14 | Sangamo Biosciences, Inc. | Methods and compositions for treating huntington's disease |
| CN106459894B (zh) * | 2014-03-18 | 2020-02-18 | 桑格摩生物科学股份有限公司 | 用于调控锌指蛋白表达的方法和组合物 |
| WO2015171932A1 (en) * | 2014-05-08 | 2015-11-12 | Sangamo Biosciences, Inc. | Methods and compositions for treating huntington's disease |
| JP6853257B2 (ja) * | 2015-09-23 | 2021-03-31 | サンガモ セラピューティクス， インコーポレイテッド | Ｈｔｔリプレッサー及びその使用 |
| GB2544270A (en) * | 2015-11-05 | 2017-05-17 | Fundació Centre De Regulació Genòmica | Nucleic acids, peptides and methods |
| US11421007B2 (en) * | 2018-04-18 | 2022-08-23 | Sangamo Therapeutics, Inc. | Zinc finger protein compositions for modulation of huntingtin (Htt) |
-
2020
- 2020-01-15 EP EP20740948.3A patent/EP3911349A4/en active Pending
- 2020-01-15 US US17/423,063 patent/US20220064237A1/en active Pending
- 2020-01-15 CN CN202080009478.4A patent/CN113301909B/zh active Active
- 2020-01-15 JP JP2021540305A patent/JP7542912B2/ja active Active
- 2020-01-15 WO PCT/US2020/013661 patent/WO2020150338A1/en not_active Ceased
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