JP2022514997A - 腫瘍の増殖及び転移を阻害するためのコルヒチンの使用 - Google Patents

腫瘍の増殖及び転移を阻害するためのコルヒチンの使用 Download PDF

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JP2022514997A
JP2022514997A JP2020541560A JP2020541560A JP2022514997A JP 2022514997 A JP2022514997 A JP 2022514997A JP 2020541560 A JP2020541560 A JP 2020541560A JP 2020541560 A JP2020541560 A JP 2020541560A JP 2022514997 A JP2022514997 A JP 2022514997A
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cancer
colchicine
release
metastasis
tumor
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JP2020541560A
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English (en)
Japanese (ja)
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リール，マイケル
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マリー アンド プール エンタープライゼズ，リミテッド
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Publication of JP2022514997A publication Critical patent/JP2022514997A/ja
Priority to JP2024000757A priority Critical patent/JP2024050581A/ja
Priority to JP2025096574A priority patent/JP2025134752A/ja
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2020541560A 2018-02-02 2019-02-01 腫瘍の増殖及び転移を阻害するためのコルヒチンの使用 Ceased JP2022514997A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2024000757A JP2024050581A (ja) 2018-02-02 2024-01-05 腫瘍の増殖及び転移を阻害するためのコルヒチンの使用
JP2025096574A JP2025134752A (ja) 2018-02-02 2025-06-10 腫瘍の増殖及び転移を阻害するためのコルヒチンの使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862625354P 2018-02-02 2018-02-02
US62/625,354 2018-02-02
PCT/EP2019/052492 WO2019149884A1 (en) 2018-02-02 2019-02-01 Use of colchicine to inhibit tumor growth and metastases

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024000757A Division JP2024050581A (ja) 2018-02-02 2024-01-05 腫瘍の増殖及び転移を阻害するためのコルヒチンの使用

Publications (1)

Publication Number Publication Date
JP2022514997A true JP2022514997A (ja) 2022-02-17

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Family Applications (3)

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JP2020541560A Ceased JP2022514997A (ja) 2018-02-02 2019-02-01 腫瘍の増殖及び転移を阻害するためのコルヒチンの使用
JP2024000757A Pending JP2024050581A (ja) 2018-02-02 2024-01-05 腫瘍の増殖及び転移を阻害するためのコルヒチンの使用
JP2025096574A Pending JP2025134752A (ja) 2018-02-02 2025-06-10 腫瘍の増殖及び転移を阻害するためのコルヒチンの使用

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JP2024000757A Pending JP2024050581A (ja) 2018-02-02 2024-01-05 腫瘍の増殖及び転移を阻害するためのコルヒチンの使用
JP2025096574A Pending JP2025134752A (ja) 2018-02-02 2025-06-10 腫瘍の増殖及び転移を阻害するためのコルヒチンの使用

Country Status (7)

Country Link
US (3) US11534415B2 (enExample)
EP (1) EP3746061A1 (enExample)
JP (3) JP2022514997A (enExample)
CN (1) CN111954524A (enExample)
CA (1) CA3089781A1 (enExample)
EA (1) EA202091736A1 (enExample)
WO (1) WO2019149884A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021089715A1 (en) * 2019-11-06 2021-05-14 Murray And Poole Enterprises, Ltd. Use of colchicine in the treatment and prevention of lung cancer
CN115068483B (zh) * 2021-03-16 2023-10-31 中国科学院上海药物研究所 Mln4924在缓解秋水仙碱中毒中的新用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101485637A (zh) * 2008-01-18 2009-07-22 普尔药物科技开发（深圳）有限公司 秋水仙碱骨架控释片或胶囊
JP2016521270A (ja) * 2013-04-16 2016-07-21 マレイ・アンド・プール・エンタープライゼズ・リミテッド コルヒチンの徐放性製剤およびその使用方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3173876A (en) 1960-05-27 1965-03-16 John C Zobrist Cleaning methods and compositions
US3276586A (en) 1963-08-30 1966-10-04 Rosaen Filter Co Indicating means for fluid filters
US3546142A (en) 1967-01-19 1970-12-08 Amicon Corp Polyelectrolyte structures
US3541006A (en) 1968-07-03 1970-11-17 Amicon Corp Ultrafiltration process
US3541005A (en) 1969-02-05 1970-11-17 Amicon Corp Continuous ultrafiltration of macromolecular solutions
US4285987A (en) 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
CA2286477A1 (en) 1997-04-11 1998-10-22 Dendreon Corporation Composition and method for inducing an immune response against tumour-related antigens
CN1748671A (zh) * 2005-08-30 2006-03-22 孔庆忠 含抗有丝分裂药物的缓释注射剂
ES2900740T3 (es) 2012-11-02 2022-03-18 Murray & Poole Entpr Ltd Tratamiento o prevención de episodios cardiovasculares mediante la administración de colchicina
JP2016540042A (ja) 2013-11-05 2016-12-22 コグネート バイオサービシズ， インコーポレイテッド がんを処置するためのチェックポイント阻害剤および治療薬の組合せ

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101485637A (zh) * 2008-01-18 2009-07-22 普尔药物科技开发（深圳）有限公司 秋水仙碱骨架控释片或胶囊
JP2016521270A (ja) * 2013-04-16 2016-07-21 マレイ・アンド・プール・エンタープライゼズ・リミテッド コルヒチンの徐放性製剤およびその使用方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"CONTROLLED RELEASE OF THE CYTARABINE AND COLCHICINE USING HYDROGEL DERIVED FROM THE POLYMERIZED MICR", A THESIS PRESENTED TO THE GRADUATE FACULTY OF THE UNIVERSITY OF AKRON, JPN6022050784, 2015, pages 1 - 90, ISSN: 0005144268 *

Also Published As

Publication number Publication date
US20210046024A1 (en) 2021-02-18
US20240099999A1 (en) 2024-03-28
EA202091736A1 (ru) 2020-10-19
US11534415B2 (en) 2022-12-27
WO2019149884A1 (en) 2019-08-08
CN111954524A (zh) 2020-11-17
JP2024050581A (ja) 2024-04-10
EP3746061A1 (en) 2020-12-09
US11877991B2 (en) 2024-01-23
US20230137776A1 (en) 2023-05-04
CA3089781A1 (en) 2019-08-08
JP2025134752A (ja) 2025-09-17

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