JP2022513562A5 - - Google Patents

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Publication number
JP2022513562A5
JP2022513562A5 JP2021516582A JP2021516582A JP2022513562A5 JP 2022513562 A5 JP2022513562 A5 JP 2022513562A5 JP 2021516582 A JP2021516582 A JP 2021516582A JP 2021516582 A JP2021516582 A JP 2021516582A JP 2022513562 A5 JP2022513562 A5 JP 2022513562A5
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JP
Japan
Prior art keywords
kda
protein
serotypes
polysaccharide
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2021516582A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022513562A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2019/058036 external-priority patent/WO2020058963A1/en
Publication of JP2022513562A publication Critical patent/JP2022513562A/ja
Publication of JP2022513562A5 publication Critical patent/JP2022513562A5/ja
Priority to JP2024130732A priority Critical patent/JP2024160305A/ja
Withdrawn legal-status Critical Current

Links

JP2021516582A 2018-09-23 2019-09-23 肺炎連鎖球菌の精製された莢膜多糖 Withdrawn JP2022513562A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024130732A JP2024160305A (ja) 2018-09-23 2024-08-07 肺炎連鎖球菌の精製された莢膜多糖

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN201841031654 2018-09-23
IN201841031653 2018-09-23
IN201841031653 2018-09-23
IN201841031654 2018-09-23
PCT/IB2019/058036 WO2020058963A1 (en) 2018-09-23 2019-09-23 Purified capsular polysaccharides of streptococcus pneumoniae

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024130732A Division JP2024160305A (ja) 2018-09-23 2024-08-07 肺炎連鎖球菌の精製された莢膜多糖

Publications (2)

Publication Number Publication Date
JP2022513562A JP2022513562A (ja) 2022-02-09
JP2022513562A5 true JP2022513562A5 (enExample) 2022-10-03

Family

ID=69886702

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021516582A Withdrawn JP2022513562A (ja) 2018-09-23 2019-09-23 肺炎連鎖球菌の精製された莢膜多糖
JP2024130732A Pending JP2024160305A (ja) 2018-09-23 2024-08-07 肺炎連鎖球菌の精製された莢膜多糖

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024130732A Pending JP2024160305A (ja) 2018-09-23 2024-08-07 肺炎連鎖球菌の精製された莢膜多糖

Country Status (12)

Country Link
US (2) US12048739B2 (enExample)
EP (1) EP3852795A4 (enExample)
JP (2) JP2022513562A (enExample)
KR (1) KR102879391B1 (enExample)
CN (1) CN113164581A (enExample)
AU (1) AU2019341723C1 (enExample)
BR (1) BR112021005425A2 (enExample)
MX (1) MX2021003358A (enExample)
MY (1) MY206212A (enExample)
PH (1) PH12021550539A1 (enExample)
WO (1) WO2020058963A1 (enExample)
ZA (1) ZA202101663B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
ES3058336T3 (es) 2017-12-06 2026-03-10 Merck Sharp & Dohme Llc Composiciones que comprenden conjugados polisacárido-proteína de Streptococcus pneumoniae y métodos de uso de los mismos
CR20210333A (es) 2018-12-19 2021-08-18 Merck Sharp & Dohme Composiciones que comprenden conjugados de polisacárido de streptococcus pneumoniae con proteína y sus métodos de uso
KR20220017996A (ko) * 2019-06-05 2022-02-14 머크 샤프 앤드 돔 코포레이션 면역원성 혈청형 35b 폐렴구균 폴리사카라이드-단백질 접합체 및 그를 제조하기 위한 접합 방법
MY207887A (en) * 2020-05-01 2025-03-26 Sinocelltech Ltd Method for improving immunogenicity of protein/peptide antigen
WO2022084852A1 (en) * 2020-10-22 2022-04-28 Pfizer Inc. Methods for purifying bacterial polysaccharides
CA3200602A1 (en) * 2020-11-04 2022-05-12 Pfizer Inc. Immunogenic compositions for use in pneumococcal vaccines
EP4288106A4 (en) * 2021-02-04 2025-06-04 Merck Sharp & Dohme LLC Lipid DNANOparticle adjuvant composition for pneumococcal conjugate vaccines
WO2024062494A1 (en) * 2022-09-19 2024-03-28 Biological E Limited Method for the purification of capsular polysaccharides
CN117512031B (zh) * 2023-10-16 2024-06-25 江苏金迪克生物技术股份有限公司 一种肺炎球菌荚膜多糖的纯化方法

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EP0027888B1 (en) 1979-09-21 1986-04-16 Hitachi, Ltd. Semiconductor switch
US4673574A (en) 1981-08-31 1987-06-16 Anderson Porter W Immunogenic conjugates
ES2204900T3 (es) 1992-02-11 2004-05-01 Henry M. Jackson Foundation For The Advancement Of Military Medicine Estructura inmuinogena de doble vector.
ATE280235T1 (de) 1993-03-05 2004-11-15 Wyeth Corp Plasmid zur herstellung von crm-protein und diphtherie-toxin
WO1995008348A1 (en) 1993-09-22 1995-03-30 Henry M. Jackson Foundation For The Advancement Of Military Medicine Method of activating soluble carbohydrate using novel cyanylating reagents for the production of immunogenic constructs
NZ304715A (en) 1995-03-22 1999-07-29 Jackson H M Found Military Med Production of immunogenic constructs using organic cyanylating reagents to activate carbohydrates and then coupling the carbohydrate to a protein, peptide or hapten
US6299881B1 (en) 1997-03-24 2001-10-09 Henry M. Jackson Foundation For The Advancement Of Military Medicine Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts
JP6502262B2 (ja) * 2012-12-20 2019-04-17 ファイザー・インク 糖複合化方法
PL3096786T3 (pl) * 2014-01-21 2021-11-08 Pfizer Inc. Polisacharydy otoczkowe streptococcus pneumoniae i ich koniugaty
CN110859957B (zh) 2014-01-21 2024-04-12 辉瑞公司 包含缀合荚膜糖抗原的免疫原性组合物及其用途
CA2968491C (en) 2014-11-20 2023-09-26 Biological E Limited Codon optimized polynucleotide for high level expression of crm197
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
EP3374376B1 (en) 2015-11-09 2020-03-18 Biological E Limited Industrially scalable process for recovering biologically active recombinant carrier proteins
EP3436061A4 (en) * 2016-03-31 2019-12-04 Liffey Biotech Limited Saccharide-polypeptide-conjugate compositions and methods of use thereof
NZ752348A (en) * 2016-09-30 2022-11-25 Biological E Ltd Multivalent pneumococcal vaccine compositions comprising polysaccharide-protein conjugates
CN110366428B (zh) * 2016-12-30 2024-05-17 Vaxcyte公司 具有非天然氨基酸的多肽-抗原缀合物
JP7680185B2 (ja) * 2017-02-24 2025-05-20 メルク・シャープ・アンド・ドーム・エルエルシー 肺炎連鎖球菌多糖-タンパク質コンジュゲートの免疫原性の増強
SMT202200356T1 (it) 2017-04-22 2022-11-18 Biological E Ltd Un metodo migliorato per produzione ad alto livello di crm
WO2019050814A1 (en) 2017-09-07 2019-03-14 Merck Sharp & Dohme Corp. ANTI-PNEUMOCOCCAL POLYSACCHARIDES AND THEIR USE IN IMMUNOGENIC CONJUGATES POLYSACCHARIDE-PROTEIN CARRIER
MX394767B (es) 2017-09-07 2025-03-24 Merck Sharp & Dohme Llc Polisacaridos neumococicos y su uso en conjugados de polisacarido inmunogenico con proteina transportadora.
CN111093650B (zh) 2017-09-07 2024-03-01 默沙东有限责任公司 肺炎球菌多糖及其在免疫原性多糖-载体蛋白缀合物中的用途

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