JP2022512994A5 - - Google Patents
Info
- Publication number
- JP2022512994A5 JP2022512994A5 JP2021525298A JP2021525298A JP2022512994A5 JP 2022512994 A5 JP2022512994 A5 JP 2022512994A5 JP 2021525298 A JP2021525298 A JP 2021525298A JP 2021525298 A JP2021525298 A JP 2021525298A JP 2022512994 A5 JP2022512994 A5 JP 2022512994A5
- Authority
- JP
- Japan
- Prior art keywords
- retroviral vector
- seq
- vector according
- acid sequence
- bisistronic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025001976A JP2025072367A (ja) | 2018-11-14 | 2025-01-06 | Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862767069P | 2018-11-14 | 2018-11-14 | |
| US62/767,069 | 2018-11-14 | ||
| PCT/US2019/061549 WO2020102589A1 (en) | 2018-11-14 | 2019-11-14 | Two-gene vectors for generating car-t cells and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025001976A Division JP2025072367A (ja) | 2018-11-14 | 2025-01-06 | Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022512994A JP2022512994A (ja) | 2022-02-07 |
| JP2022512994A5 true JP2022512994A5 (enExample) | 2022-11-22 |
Family
ID=70732194
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021525298A Pending JP2022512994A (ja) | 2018-11-14 | 2019-11-14 | Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用 |
| JP2025001976A Pending JP2025072367A (ja) | 2018-11-14 | 2025-01-06 | Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025001976A Pending JP2025072367A (ja) | 2018-11-14 | 2025-01-06 | Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20210395779A1 (enExample) |
| EP (1) | EP3864052A4 (enExample) |
| JP (2) | JP2022512994A (enExample) |
| KR (1) | KR20210091250A (enExample) |
| CN (2) | CN120519520A (enExample) |
| AU (1) | AU2019378039A1 (enExample) |
| CA (1) | CA3119296A1 (enExample) |
| MA (1) | MA53877A (enExample) |
| SG (1) | SG11202104334SA (enExample) |
| WO (1) | WO2020102589A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102763121B1 (ko) | 2015-02-06 | 2025-02-04 | 내셔널 유니버시티 오브 싱가포르 | 치료적 면역 세포의 효능의 향상 방법 |
| NZ752984A (en) | 2016-11-22 | 2026-03-27 | Nat Univ Singapore | Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies |
| GB201719646D0 (en) | 2017-11-27 | 2018-01-10 | Bivictrix Therapeutics Ltd | Therapy |
| CN112300282A (zh) * | 2020-11-03 | 2021-02-02 | 南京北恒生物科技有限公司 | 靶向cd7的人源化抗体及其用途 |
| CN114525259B (zh) * | 2020-11-03 | 2025-02-14 | 南京北恒生物科技有限公司 | 靶向cd7的嵌合抗原受体及其用途 |
| CN114525306B (zh) * | 2020-11-23 | 2025-01-28 | 博生吉医药科技(苏州)有限公司 | 一种cd7-car-t细胞的制备方法及应用 |
| GB202020572D0 (en) * | 2020-12-23 | 2021-02-03 | Bivictrix Therapeutics Ltd | Novel methods of therapy |
| GB202020573D0 (en) * | 2020-12-23 | 2021-02-03 | Bivictrix Therapeutics Ltd | Novel methods of therapy |
| CN113234682B (zh) * | 2021-01-12 | 2023-02-21 | 上海雅科生物科技有限公司 | 靶向cd7的工程化免疫细胞、嵌合抗原受体、cd7阻断分子及应用 |
| US20250099504A1 (en) * | 2022-03-29 | 2025-03-27 | Institute Of Hematology And Blood Diseases Hospital , Chinese Academy Of Medical Sciences | Antibody that specifically binds to cd7 and use thereof in preparing chimeric antigen receptor |
| CN120025438A (zh) * | 2023-11-21 | 2025-05-23 | 合源生物科技(天津)有限公司 | 一种靶向cd7的人源化抗体、嵌合抗原受体及其应用 |
| CN118221810A (zh) * | 2024-03-05 | 2024-06-21 | 武汉生物制品研究所有限责任公司 | 一种能够结合ev-a71的单克隆抗体及其应用 |
| CN120865430A (zh) * | 2024-04-30 | 2025-10-31 | 合源生物科技(天津)有限公司 | 一种增强型嵌合抗原受体及其应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0281604B1 (en) | 1986-09-02 | 1993-03-31 | Enzon Labs Inc. | Single polypeptide chain binding molecules |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| HK1047109A1 (zh) | 1999-10-15 | 2003-02-07 | University Of Massachusetts | 作为指定基因干预工具的rna干预轨迹基因 |
| US6326193B1 (en) | 1999-11-05 | 2001-12-04 | Cambria Biosciences, Llc | Insect control agent |
| AU2001275474A1 (en) | 2000-06-12 | 2001-12-24 | Akkadix Corporation | Materials and methods for the control of nematodes |
| JP6647868B2 (ja) * | 2013-02-20 | 2020-02-14 | ノバルティス アーゲー | ヒト化抗ＥＧＦＲｖＩＩＩキメラ抗原受容体を用いたがんの処置 |
| CN113684185A (zh) * | 2013-02-26 | 2021-11-23 | 纪念斯隆-凯特琳癌症中心 | 用于免疫疗法的组合物和方法 |
| WO2016049024A2 (en) * | 2014-09-24 | 2016-03-31 | The Broad Institute Inc. | Delivery, use and therapeutic applications of the crispr-cas systems and compositions for modeling competition of multiple cancer mutations in vivo |
| KR102763121B1 (ko) | 2015-02-06 | 2025-02-04 | 내셔널 유니버시티 오브 싱가포르 | 치료적 면역 세포의 효능의 향상 방법 |
| KR20180118175A (ko) * | 2016-03-04 | 2018-10-30 | 노파르티스 아게 | 다중 키메라 항원 수용체 (car) 분자를 발현하는 세포 및 그에 따른 용도 |
| NZ752984A (en) * | 2016-11-22 | 2026-03-27 | Nat Univ Singapore | Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies |
| US20190038733A1 (en) * | 2017-08-10 | 2019-02-07 | National University Of Singapore | T cell receptor-deficient chimeric antigen receptor t-cells and methods of use thereof |
| EP3784776A4 (en) * | 2018-05-23 | 2022-01-26 | National University of Singapore | Blockade of cd2 surface expression and expression of chimeric antigen receptors for immunotherapy of t-cell malignancies |
| JP2021525067A (ja) * | 2018-05-23 | 2021-09-24 | ナショナル ユニバーシティ オブ シンガポール | Ｔ細胞悪性腫瘍の免疫療法のためのキメラ抗原受容体およびｃｄ２の遺伝子編集 |
-
2019
- 2019-11-14 MA MA053877A patent/MA53877A/fr unknown
- 2019-11-14 CN CN202510607212.4A patent/CN120519520A/zh active Pending
- 2019-11-14 US US17/291,580 patent/US20210395779A1/en active Pending
- 2019-11-14 WO PCT/US2019/061549 patent/WO2020102589A1/en not_active Ceased
- 2019-11-14 SG SG11202104334SA patent/SG11202104334SA/en unknown
- 2019-11-14 KR KR1020217017844A patent/KR20210091250A/ko not_active Ceased
- 2019-11-14 JP JP2021525298A patent/JP2022512994A/ja active Pending
- 2019-11-14 CA CA3119296A patent/CA3119296A1/en active Pending
- 2019-11-14 EP EP19883740.3A patent/EP3864052A4/en active Pending
- 2019-11-14 CN CN201980082104.2A patent/CN113227144B/zh active Active
- 2019-11-14 AU AU2019378039A patent/AU2019378039A1/en active Pending
-
2025
- 2025-01-06 JP JP2025001976A patent/JP2025072367A/ja active Pending
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