JP2022512781A5 - - Google Patents

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Publication number
JP2022512781A5
JP2022512781A5 JP2021521816A JP2021521816A JP2022512781A5 JP 2022512781 A5 JP2022512781 A5 JP 2022512781A5 JP 2021521816 A JP2021521816 A JP 2021521816A JP 2021521816 A JP2021521816 A JP 2021521816A JP 2022512781 A5 JP2022512781 A5 JP 2022512781A5
Authority
JP
Japan
Prior art keywords
patient
antibody
hematopoietic stem
stem cells
immunosuppressant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021521816A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022512781A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/058973 external-priority patent/WO2020092655A1/en
Publication of JP2022512781A publication Critical patent/JP2022512781A/ja
Publication of JP2022512781A5 publication Critical patent/JP2022512781A5/ja
Priority to JP2024213792A priority Critical patent/JP2025038016A/ja
Pending legal-status Critical Current

Links

JP2021521816A 2018-10-30 2019-10-30 同種造血幹細胞移植の方法 Pending JP2022512781A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024213792A JP2025038016A (ja) 2018-10-30 2024-12-06 同種異系の造血幹細胞移植の方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862752828P 2018-10-30 2018-10-30
US62/752,828 2018-10-30
US201862773873P 2018-11-30 2018-11-30
US62/773,873 2018-11-30
US201962882362P 2019-08-02 2019-08-02
US62/882,362 2019-08-02
PCT/US2019/058973 WO2020092655A1 (en) 2018-10-30 2019-10-30 Methods for allogeneic hematopoietic stem cell transplantation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024213792A Division JP2025038016A (ja) 2018-10-30 2024-12-06 同種異系の造血幹細胞移植の方法

Publications (2)

Publication Number Publication Date
JP2022512781A JP2022512781A (ja) 2022-02-07
JP2022512781A5 true JP2022512781A5 (enExample) 2022-11-07

Family

ID=70462151

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021521816A Pending JP2022512781A (ja) 2018-10-30 2019-10-30 同種造血幹細胞移植の方法
JP2024213792A Pending JP2025038016A (ja) 2018-10-30 2024-12-06 同種異系の造血幹細胞移植の方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024213792A Pending JP2025038016A (ja) 2018-10-30 2024-12-06 同種異系の造血幹細胞移植の方法

Country Status (12)

Country Link
US (1) US20210379195A1 (enExample)
EP (1) EP3877415A4 (enExample)
JP (2) JP2022512781A (enExample)
KR (1) KR20210086683A (enExample)
CN (1) CN113301923A (enExample)
AU (1) AU2019374055A1 (enExample)
BR (1) BR112021008437A2 (enExample)
CA (1) CA3117366A1 (enExample)
IL (1) IL282637A (enExample)
MX (1) MX2021004579A (enExample)
SG (1) SG11202104084WA (enExample)
WO (1) WO2020092655A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110740641A (zh) 2016-11-30 2020-01-31 杰克逊实验室 具有改善的人先天免疫细胞发育的人源化小鼠模型
WO2019084057A2 (en) 2017-10-24 2019-05-02 Magenta Therapeutics, Inc. COMPOSITIONS AND METHODS FOR DEPLOYING CD117 + CELLS
AU2019265019B2 (en) 2018-05-11 2025-11-06 Beam Therapeutics Inc. Methods of substituting pathogenic amino acids using programmable base editor systems
JP2022530443A (ja) * 2019-04-24 2022-06-29 マジェンタ セラピューティクス インコーポレイテッド 抗cd117抗体薬物複合体およびその使用
EP3958909A4 (en) * 2019-04-24 2024-01-10 Magenta Therapeutics, Inc. ANTI-CD117 ANTIBODY DRUG CONJUGATES AND USES THEREOF
EP3959242A4 (en) * 2019-04-24 2023-09-13 Magenta Therapeutics, Inc. ANTRACYCLINE ANTIBODY-DRUG CONJUGATES AND THEIR USES
GB202015226D0 (en) * 2020-09-25 2020-11-11 Adc Therapeutics S A Pyrrol obenzodiazepine-antibody conugates and uses thereof
US12496303B2 (en) * 2020-10-19 2025-12-16 Washington University Conditioning agents for use in allogeneic hematopoietic stem cell transplantation
EP4433512A4 (en) 2021-11-19 2025-12-31 Univ Pennsylvania Genetically modified pan-leukocyte-specific CD45 antigen to facilitate T-lymphocyte therapy
IL313760A (en) * 2021-12-22 2024-08-01 Jackson Lab Human mouse models
AU2022422572A1 (en) * 2021-12-23 2024-06-06 Cimeio Therapeutics Ag Discernible cell surface protein variants of cd45 for use in cell therapy
EP4486784A1 (en) * 2022-03-01 2025-01-08 CSL Innovation Pty Ltd Methods of bone marrow conditioning
JP2025510189A (ja) * 2022-03-24 2025-04-14 アクティニウム ファーマシューティカルズ インコーポレイテッド ヒト化抗cd45抗体

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1585799A (en) * 1997-11-14 1999-06-07 General Hospital Corporation, The Treatment of hematologic disorders
US20120045435A1 (en) * 2010-08-18 2012-02-23 Theresa Deisher Compositions and methods to inhibit stem cell and progenitor cell binding to lymphoid tissue and for regenerating germinal centers in lymphatic tissues
HK1256681A1 (zh) * 2015-04-06 2019-10-04 President And Fellows Of Harvard College 用於非清髓性预处理的组合物和方法
IL263744B2 (en) * 2016-06-17 2023-11-01 Magenta Therapeutics Inc Compositions and methods for the depletion of cd117 plus cells
CN109641051A (zh) * 2016-06-17 2019-04-16 美真达治疗公司 用于耗尽细胞的组合物和方法
EP3877416A4 (en) * 2018-10-30 2022-07-27 Magenta Therapeutics, Inc. ANTI-CD45 ANTIBODIES AND CONJUGATES THEREOF
JP7650819B2 (ja) * 2019-04-24 2025-03-25 ブイオーアール バイオファーマ インコーポレーテッド 抗-cd45抗体薬物コンジュゲート及びその使用
JP2022535527A (ja) * 2019-06-04 2022-08-09 マジェンタ セラピューティクス インコーポレイテッド 自己免疫疾患を治療するための方法および組成物
IL292628A (en) * 2019-11-01 2022-07-01 Magenta Therapeutics Inc Anti-cd45 antibody and conjugates accordingly

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