JP2022512709A - 炎症性疾患及び自己免疫疾患を処置する組成物及び方法 - Google Patents

炎症性疾患及び自己免疫疾患を処置する組成物及び方法 Download PDF

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JP2022512709A
JP2022512709A JP2021520947A JP2021520947A JP2022512709A JP 2022512709 A JP2022512709 A JP 2022512709A JP 2021520947 A JP2021520947 A JP 2021520947A JP 2021520947 A JP2021520947 A JP 2021520947A JP 2022512709 A JP2022512709 A JP 2022512709A
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antibody
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amino acid
acid sequence
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シャイルバハイ クンワル
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ティジアーナ ライフ サイエンシズ パブリック リミティド カンパニー
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
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    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K31/558Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
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    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Microbiology (AREA)
  • Mycology (AREA)
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  • Endocrinology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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JP2021520947A 2018-10-31 2019-10-31 炎症性疾患及び自己免疫疾患を処置する組成物及び方法 Pending JP2022512709A (ja)

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US201862753445P 2018-10-31 2018-10-31
US62/753,445 2018-10-31
PCT/EP2019/079836 WO2020089396A2 (fr) 2018-10-31 2019-10-31 Compositions et procédés de traitement de maladies inflammatoires et auto-immunes

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JP2022512709A true JP2022512709A (ja) 2022-02-07
JPWO2020089396A5 JPWO2020089396A5 (fr) 2022-11-09

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US (1) US20220008533A1 (fr)
EP (1) EP3873521A2 (fr)
JP (1) JP2022512709A (fr)
CN (1) CN113329771A (fr)
AU (1) AU2019373663A1 (fr)
CA (1) CA3112868A1 (fr)
WO (1) WO2020089396A2 (fr)

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CA3109711A1 (fr) 2018-09-21 2020-03-26 Tenova Goodfellow Inc. Appareil in situ de mesure d'un constituant et de la vitesse d'ecoulement d'un degagement gazeux d'un four
KR20230031981A (ko) 2019-05-14 2023-03-07 프로벤션 바이오, 인코포레이티드 제1형 당뇨병을 예방하기 위한 방법 및 조성물
MX2022015872A (es) 2020-06-11 2023-05-16 Provention Bio Inc Metodos y composiciones para prevenir diabetes tipo 1.
WO2022063979A1 (fr) * 2020-09-24 2022-03-31 Universität Zürich Spermidine dans le traitement de la dysbiose et des affections inflammatoires associées du tractus gastro-intestinal
WO2022221767A1 (fr) * 2021-04-16 2022-10-20 Tiziana Life Sciences Plc Administration sous-cutanée d'anticorps pour le traitement d'une maladie
CN114350616A (zh) * 2022-01-24 2022-04-15 深圳市先康达生命科学有限公司 一种免疫细胞及其制备方法和应用

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JP2016514671A (ja) * 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
WO2018044948A1 (fr) * 2016-08-29 2018-03-08 Tiziana Life Sciences Plc Formulations d'anticorps anti-cd3

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ATE470453T1 (de) 2004-04-06 2010-06-15 Novimmune Sa Verfahren zur behandlung von atherosklerose
SG155883A1 (en) 2004-06-03 2009-10-29 Novimmune Sa Anti-cd3 antibodies and methods of use thereof
JP2010531138A (ja) * 2007-06-13 2010-09-24 ラ ホヤ インスティテュート フォア アラージー アンド イムノロジー 制御性t細胞ならびに同製造および使用方法
BR122016016837A2 (pt) * 2011-05-21 2019-08-27 Macrogenics Inc moléculas de ligação a cd3; anticorpos de ligação a cd3; composições farmacêuticas; e usos da molécula de ligação a cd3
US10000567B2 (en) * 2012-06-14 2018-06-19 Therapix Biosciences Ltd. Humanized antibodies to cluster of differentiation 3 (CD3)
WO2017217985A1 (fr) * 2016-06-15 2017-12-21 Amgen Inc. Procédés et compositions pour le traitement de la maladie cœliaque, sensibilité au gluten non cœliaque et maladie cœliaque réfractaire

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
JP2016514671A (ja) * 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
WO2018044948A1 (fr) * 2016-08-29 2018-03-08 Tiziana Life Sciences Plc Formulations d'anticorps anti-cd3

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Title
DAWSON HARRY D; ET AL: "DIRECT AND INDIRECT EFFECTS OF RETINOIC ACID ON HUMAN TH2 CYTOKINE AND CHEMOKINE 以下備考", BMC IMMUNOLOGY, vol. VOL:7, NR:1, JPN5022001904, 21 November 2006 (2006-11-21), GB, pages 27 - 1, ISSN: 0005150136 *
LIVIA RAMOS GOES; ET AL: "MADCAM SIGNALS THROUGH INTEGRIN-[ALPHA]4[BETA]7 INDUCING CELLULAR ACTIVATION AND HIV REPLICATION", AIDS RESEARCH AND HUMAN RETROVIRUSES, JPN5022001902, 22 October 2018 (2018-10-22), pages 308, ISSN: 0005150135 *
TATIANA TAKIISHI; ET AL: "REVERSAL OF DIABETES IN NOD MICE BY CLINICAL-GRADE PROINSULIN AND IL-10-SECRETING 以下備考", DIABETES, vol. VOL:66, NR:2, JPN5022001900, 8 November 2016 (2016-11-08), US, pages 448 - 459, ISSN: 0005150134 *

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Publication number Publication date
AU2019373663A1 (en) 2021-04-08
CA3112868A1 (fr) 2020-05-07
US20220008533A1 (en) 2022-01-13
CN113329771A (zh) 2021-08-31
EP3873521A2 (fr) 2021-09-08
WO2020089396A3 (fr) 2020-07-23
WO2020089396A2 (fr) 2020-05-07

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