JP2022512650A5 - - Google Patents
Info
- Publication number
- JP2022512650A5 JP2022512650A5 JP2021519644A JP2021519644A JP2022512650A5 JP 2022512650 A5 JP2022512650 A5 JP 2022512650A5 JP 2021519644 A JP2021519644 A JP 2021519644A JP 2021519644 A JP2021519644 A JP 2021519644A JP 2022512650 A5 JP2022512650 A5 JP 2022512650A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- amino acid
- variant
- reference antibody
- dna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025167548A JP2026016427A (ja) | 2018-10-22 | 2025-10-03 | 抗体ライブラリー及び方法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1817188.4A GB201817188D0 (en) | 2018-10-22 | 2018-10-22 | Antibody library |
| GB1817188.4 | 2018-10-22 | ||
| GB1904754.7 | 2019-04-04 | ||
| GBGB1904754.7A GB201904754D0 (en) | 2019-04-04 | 2019-04-04 | Antibody library and method |
| GBGB1905032.7A GB201905032D0 (en) | 2019-04-09 | 2019-04-09 | Antibody library and method |
| GB1905032.7 | 2019-04-09 | ||
| PCT/GB2019/053010 WO2020084298A1 (en) | 2018-10-22 | 2019-10-22 | Antibody library and method |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025167548A Division JP2026016427A (ja) | 2018-10-22 | 2025-10-03 | 抗体ライブラリー及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022512650A JP2022512650A (ja) | 2022-02-07 |
| JP2022512650A5 true JP2022512650A5 (https=) | 2025-10-30 |
| JP7853096B2 JP7853096B2 (ja) | 2026-04-28 |
Family
ID=68393020
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021519644A Active JP7853096B2 (ja) | 2018-10-22 | 2019-10-22 | 抗体ライブラリー及び方法 |
| JP2025167548A Pending JP2026016427A (ja) | 2018-10-22 | 2025-10-03 | 抗体ライブラリー及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025167548A Pending JP2026016427A (ja) | 2018-10-22 | 2025-10-03 | 抗体ライブラリー及び方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US12378696B2 (https=) |
| EP (1) | EP3870607A1 (https=) |
| JP (2) | JP7853096B2 (https=) |
| KR (1) | KR20210084509A (https=) |
| CN (1) | CN113195537A (https=) |
| AU (1) | AU2019365135A1 (https=) |
| BR (1) | BR112021007529A2 (https=) |
| CA (1) | CA3115150A1 (https=) |
| MX (1) | MX2021004149A (https=) |
| WO (1) | WO2020084298A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7473339B2 (ja) * | 2017-03-07 | 2024-04-23 | エフ． ホフマン－ラ ロシュ アーゲー | 代替の抗原特異的抗体変異体を発見するための方法 |
| CN112289369B (zh) * | 2020-12-15 | 2021-04-02 | 武汉华美生物工程有限公司 | 一种基于深度学习的抗体库构建方法及装置 |
| CN114775065B (zh) * | 2022-04-22 | 2026-01-06 | 武汉华美生物工程有限公司 | 一种半合成纳米抗体库构建方法和纳米抗体库 |
| CN115171774A (zh) * | 2022-05-17 | 2022-10-11 | 慧壹科技(上海)有限公司 | 一种抗体/大分子药物的亲和力改造系统和方法 |
| CN117736329B (zh) * | 2023-12-25 | 2024-11-12 | 华润生物医药有限公司 | 抗pd-1抗体及其用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2011801A1 (en) * | 1999-05-27 | 2009-01-07 | Government of the United States as represented by the Secretary, Department of Health and Human Services | Immunoconjugates having high binding affinity |
| WO2016188911A1 (en) * | 2015-05-22 | 2016-12-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Human monoclonal antibodies fragments inhibiting both the cath-d catalytic activity and its binding to the lrp1 receptor |
| CN109576292B (zh) * | 2018-12-21 | 2022-11-29 | 深圳市爱思迪生物科技有限公司 | 一种抗体文库的构建方法及其应用 |
-
2019
- 2019-10-22 US US17/287,441 patent/US12378696B2/en active Active
- 2019-10-22 MX MX2021004149A patent/MX2021004149A/es unknown
- 2019-10-22 KR KR1020217015023A patent/KR20210084509A/ko active Pending
- 2019-10-22 BR BR112021007529-1A patent/BR112021007529A2/pt unknown
- 2019-10-22 WO PCT/GB2019/053010 patent/WO2020084298A1/en not_active Ceased
- 2019-10-22 AU AU2019365135A patent/AU2019365135A1/en active Pending
- 2019-10-22 CN CN201980081249.0A patent/CN113195537A/zh active Pending
- 2019-10-22 CA CA3115150A patent/CA3115150A1/en active Pending
- 2019-10-22 JP JP2021519644A patent/JP7853096B2/ja active Active
- 2019-10-22 EP EP19795614.7A patent/EP3870607A1/en active Pending
-
2025
- 2025-06-20 US US19/244,919 patent/US20250382726A1/en active Pending
- 2025-10-03 JP JP2025167548A patent/JP2026016427A/ja active Pending