JP2022511693A - 動物における代謝健康を増進する方法 - Google Patents
動物における代謝健康を増進する方法 Download PDFInfo
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Abstract
Description
[0001]本出願は、2018年12月13日に出願された米国仮出願第62/779,139号の優先権を主張するものであり、その開示の全体が本参照により本明細書に組み込まれる。
[0006]一実施形態では、動物における代謝健康を増進する方法は、非ケトジェニックな組成物(non-ketogenic compsition)を動物に投与する工程を含むことができ、非ケトジェニックな組成物は、約5%~約25%の炭水化物と、約30%~約60%のタンパク質と、約10%~約40%の脂肪とを含む。加えて、組成物は、少なくとも2:1のタンパク質対炭水化物比を有し得る。
[0008]用語「動物」は減量中に除脂肪体重を維持する必要がある任意の動物を意味し、ヒト、鳥類、ウシ科動物、イヌ科動物、ウマ科動物、ネコ科動物、ヤギ類、オオカミ類、ネズミ科動物、ヒツジ類又はブタ類が挙げられる。一態様では、動物は哺乳類であり得る。
[発明を実施するための形態]
[0055]48匹の雄性SDラットを、十分に制御された室温、湿度、及び12時間の明/暗サイクル下の齧歯類室において、1匹ずつラットケージに収容した。ラットには、11日間、対照食(D601、41%炭水化物、34%脂肪、及び25%タンパク質)及び水を自由に摂取させ、新しい環境に順応させた。この期間中に、1週間ごとの体重及び1日当たりの摂食量を測定した。
[0063]48匹の雄性SDラットを、十分に制御された室温、湿度、及び12時間の明/暗サイクル下の齧歯類室において、1匹ずつラットケージに収容した。ラットには、11日間、対照食(D601、41%炭水化物、34%脂肪、及び25%タンパク質)及び水を自由に摂取させ、新しい環境に順応させた。この期間中に、1週間ごとの体重及び1日当たりの摂食量を測定した。
[0068]48匹の雄性SDラットを、十分に制御された室温、湿度、及び12時間の明/暗サイクル下の齧歯類室において、1匹ずつラットケージに収容した。上記ラットには、11日間、対照食(D601、41%炭水化物、34%脂肪、及び25%タンパク質)及び水を自由に摂取させ、新しい環境に順応させた。この期間中に、1週間ごとの体重及び1日当たりの摂食量を測定した。
[0072]48匹の雄性SDラットを、十分に制御された室温、湿度、及び12時間の明/暗サイクル下の齧歯類室において、1匹ずつラットケージに収容した。ラットには、11日間、対照食(D601、41%炭水化物、34%脂肪、及び25%タンパク質)及び水を自由に摂取させ、新しい環境に順応させた。この期間中に、1週間ごとの体重及び1日当たりの摂食量を測定した。
[0075]48匹の雄性SDラットを、十分に制御された室温、湿度、及び12時間の明/暗サイクル下の齧歯類室において、1匹ずつラットケージに収容した。上記ラットには、11日間、対照食(D601、41%炭水化物、34%脂肪、及び25%タンパク質)及び水を自由に摂取させ、新しい環境に順応させた。この期間中に、1週間ごとの体重及び1日当たりの摂食量を測定した。
Claims (10)
- 動物における代謝健康を増進するための方法であって、
非ケトジェニックな食品組成物を前記動物に投与する工程を含み、
前記非ケトジェニックな食品組成物が、
約30%~約65%のタンパク質と、
約5%~約25%の炭水化物と、
約10%~約40%の脂肪と、を含み、
前記非ケトジェニックな食品組成物が、少なくとも2:1のタンパク質対炭水化物比を有する、方法。 - 前記タンパク質が、前記非ケトジェニックな食品組成物の約45%~55%を構成する、請求項1に記載の方法。
- 前記炭水化物が、前記非ケトジェニックな食品組成物の約10%~約20%を構成する、請求項1に記載の方法。
- 前記脂肪が、前記非ケトジェニックな食品組成物の約25%~約35%を構成する、請求項1に記載の方法。
- 前記非ケトジェニックな食品組成物が、前記動物に定期的に投与される、請求項1に記載の方法。
- 前記タンパク質対炭水化物比が、約2:1~約6:1の範囲である、請求項1に記載の方法。
- 前記非ケトジェニックな食品組成物が、ペットフード組成物である、請求項1に記載の方法。
- 前記動物が、コンパニオンアニマルである、請求項1に記載の方法。
- 前記非ケトジェニックな食品組成物を摂取していないときの前記動物の血中遊離脂肪酸値、総コレステロール値、トリアシルグリセロール値、血中グルコース値、及びインスリン値と比較して、より低い血中遊離脂肪酸値、より低い総コレステロール値、より低いトリアシルグリセロール値、より低いインスリン値、より低い血中グルコース値、及びこれらの組み合わせをもたらす、請求項1に記載の方法。
- 体脂肪の低減、内臓脂肪の低減、腹部脂肪の低減、体重の低減、体重増加の低減、インスリン抵抗性の低減、低コレステロール、低グルコース、低トリグリセリド、低インスリン、自発的な食物摂取の減少、満腹感の増強、脂肪酸化の最大化、グルコース酸化の最大化、インスリン感受性の改善、メタボリックシンドロームのリスク低減、糖尿病のリスク低減、心血管疾患のリスク低減、及びこれらの組み合わせからなる群から選択される健康効果をもたらす、請求項1に記載の方法。
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US201862779139P | 2018-12-13 | 2018-12-13 | |
US62/779,139 | 2018-12-13 | ||
PCT/IB2019/060530 WO2020121145A1 (en) | 2018-12-13 | 2019-12-06 | Methods for enhancing metabolic health in an animal |
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CA (1) | CA3116822A1 (ja) |
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US6203825B1 (en) * | 1998-09-02 | 2001-03-20 | Heska Corporation | Method and composition to protect an obligate carnivore from a disease of abnormal carbohydrate metabolism |
JP2018502555A (ja) * | 2014-11-25 | 2018-02-01 | ネステク ソシエテ アノニム | 除脂肪体重を高め、体脂肪の増加を最小化し、かつ体重を管理するための方法及び組成物 |
JP2018502554A (ja) * | 2014-11-25 | 2018-02-01 | ネステク ソシエテ アノニム | 減量中に除脂肪体重を維持し、かつ脂肪の低減を促進するための方法及び組成物 |
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US5952033A (en) | 1996-12-24 | 1999-09-14 | Nestec S.A. | Gelatinized cereal product containing oligosaccharide and processes of preparing and using same |
PT862863E (pt) | 1997-01-09 | 2002-04-29 | Nestle Sa | Produto cerealifero contendo probioticos |
MXPA02002430A (es) | 1999-09-07 | 2002-07-02 | Nestle Sa | Metodo para mejorar la piel y el pelo de mascotas. |
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- 2019-12-06 MX MX2021005669A patent/MX2021005669A/es unknown
- 2019-12-06 BR BR112021007056-7A patent/BR112021007056A2/pt unknown
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- 2019-12-06 AU AU2019396727A patent/AU2019396727A1/en active Pending
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AU2019396727A1 (en) | 2021-05-06 |
CA3116822A1 (en) | 2020-06-18 |
BR112021007056A2 (pt) | 2021-07-20 |
CN113163801A (zh) | 2021-07-23 |
US20200187526A1 (en) | 2020-06-18 |
MX2021005669A (es) | 2021-06-08 |
EP3893661A1 (en) | 2021-10-20 |
US11576403B2 (en) | 2023-02-14 |
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