JP2022510410A - 去勢抵抗性および去勢感受性前立腺がんを処置するための方法 - Google Patents
去勢抵抗性および去勢感受性前立腺がんを処置するための方法 Download PDFInfo
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- JP2022510410A JP2022510410A JP2021531722A JP2021531722A JP2022510410A JP 2022510410 A JP2022510410 A JP 2022510410A JP 2021531722 A JP2021531722 A JP 2021531722A JP 2021531722 A JP2021531722 A JP 2021531722A JP 2022510410 A JP2022510410 A JP 2022510410A
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- prostate cancer
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- YRNFLVUMZIRYKY-BLLLJJGKSA-N CN(CC[C@@H]1c(c(OC(c2ccccc2Cl)=C2)c(c(O)c3)C2=O)c3OP(O)(O)=O)C[C@H]1O Chemical compound CN(CC[C@@H]1c(c(OC(c2ccccc2Cl)=C2)c(c(O)c3)C2=O)c3OP(O)(O)=O)C[C@H]1O YRNFLVUMZIRYKY-BLLLJJGKSA-N 0.000 description 4
- YRNFLVUMZIRYKY-BLLLJJGKSA-O C[NH+](CC[C@@H]1c(c(OC(c2ccccc2Cl)=C2)c(c(O)c3)C2=O)c3OP(O)(O)=O)C[C@H]1O Chemical compound C[NH+](CC[C@@H]1c(c(OC(c2ccccc2Cl)=C2)c(c(O)c3)C2=O)c3OP(O)(O)=O)C[C@H]1O YRNFLVUMZIRYKY-BLLLJJGKSA-O 0.000 description 1
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A61K31/66—Phosphorus compounds
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/12—Animals modified by administration of exogenous cells
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/30—Animals modified by surgical methods
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- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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- A01K2267/00—Animals characterised by purpose
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
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- Immunology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862776985P | 2018-12-07 | 2018-12-07 | |
| US62/776,985 | 2018-12-07 | ||
| US201962909147P | 2019-10-01 | 2019-10-01 | |
| US62/909,147 | 2019-10-01 | ||
| US201962926390P | 2019-10-25 | 2019-10-25 | |
| US62/926,390 | 2019-10-25 | ||
| PCT/US2019/065069 WO2020118252A1 (en) | 2018-12-07 | 2019-12-06 | Methods for treating castration-resistant and castration- sensitive prostate cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022510410A true JP2022510410A (ja) | 2022-01-26 |
| JP2022510410A5 JP2022510410A5 (https=) | 2022-11-29 |
| JPWO2020118252A5 JPWO2020118252A5 (https=) | 2022-11-29 |
Family
ID=70974424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021531722A Pending JP2022510410A (ja) | 2018-12-07 | 2019-12-06 | 去勢抵抗性および去勢感受性前立腺がんを処置するための方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20200281949A1 (https=) |
| EP (1) | EP3891294A4 (https=) |
| JP (1) | JP2022510410A (https=) |
| KR (1) | KR20210100145A (https=) |
| CN (1) | CN113164500A (https=) |
| AU (1) | AU2019395100A1 (https=) |
| CA (1) | CA3120850A1 (https=) |
| MX (1) | MX2021005075A (https=) |
| WO (1) | WO2020118252A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10471023B2 (en) | 2015-03-12 | 2019-11-12 | British Columbia Cancer Agency Branch | Bisphenol ether derivatives and methods for using the same |
| ES2739749T3 (es) | 2015-05-18 | 2020-02-03 | Tolero Pharmaceuticals Inc | Profármacos de alvocidib que tienen biodisponibilidad aumentada |
| US20170298033A1 (en) | 2016-04-15 | 2017-10-19 | The University Of British Columbia | Bisphenol derivatives and their use as androgen receptor activity modulators |
| WO2018094275A1 (en) | 2016-11-18 | 2018-05-24 | Tolero Pharmaceuticals, Inc. | Alvocidib prodrugs and their use as protein kinase inhibitors |
| WO2019055579A1 (en) | 2017-09-12 | 2019-03-21 | Tolero Pharmaceuticals, Inc. | TREATMENT REGIME FOR CANCERS THAT ARE INSENSITIVE TO BCL-2 INHIBITORS USING THE MCL-1 ALVOCIDIB INHIBITOR |
| US20190240198A1 (en) * | 2018-02-05 | 2019-08-08 | Dean G. Tang | Formulations and methods for the treatment of cancers |
| US11034710B2 (en) | 2018-12-04 | 2021-06-15 | Sumitomo Dainippon Pharma Oncology, Inc. | CDK9 inhibitors and polymorphs thereof for use as agents for treatment of cancer |
| US11793802B2 (en) | 2019-03-20 | 2023-10-24 | Sumitomo Pharma Oncology, Inc. | Treatment of acute myeloid leukemia (AML) with venetoclax failure |
| WO2020198712A1 (en) | 2019-03-28 | 2020-10-01 | Essa Pharma, Inc. | Pharmaceutical compositions and combinations comprising inhibitors of the androgen receptor and uses thereof |
| AU2021255723A1 (en) | 2020-04-17 | 2022-12-08 | Essa Pharma, Inc. | Solid forms of an N-terminal domain androgen receptor inhibitor and uses thereof |
| WO2022221661A1 (en) * | 2021-04-16 | 2022-10-20 | Essa Pharma, Inc. | Pharmaceutical compositions comprising inhibitors of the androgen receptor and uses thereof |
| WO2023114264A1 (en) * | 2021-12-15 | 2023-06-22 | Eli Lilly And Company | Combination for treatment of high-risk metastatic hormone-sensitive prostate cancer |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017534248A (ja) * | 2014-08-25 | 2017-11-24 | ザ ジョンズ ホプキンズ ユニヴァーシティー | 前立腺がん治療に関する方法及び組成物 |
| JP2018517686A (ja) * | 2015-05-18 | 2018-07-05 | トレロ ファーマシューティカルズ, インコーポレイテッド | バイオアベイラビリティが高いアルボシジブプロドラッグ |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001080896A2 (en) * | 2000-04-21 | 2001-11-01 | Arch Development Corporation | Flavopiridol drug combinations and methods with reduced side effects |
| CN104812756A (zh) * | 2012-09-26 | 2015-07-29 | 曼凯德公司 | 多激酶通路抑制剂 |
| SG10201907684PA (en) * | 2013-01-15 | 2019-10-30 | Aragon Pharmaceuticals Inc | Androgen receptor modulator and uses thereof |
| WO2018094275A1 (en) * | 2016-11-18 | 2018-05-24 | Tolero Pharmaceuticals, Inc. | Alvocidib prodrugs and their use as protein kinase inhibitors |
| US11034710B2 (en) * | 2018-12-04 | 2021-06-15 | Sumitomo Dainippon Pharma Oncology, Inc. | CDK9 inhibitors and polymorphs thereof for use as agents for treatment of cancer |
-
2019
- 2019-12-06 CN CN201980080943.0A patent/CN113164500A/zh active Pending
- 2019-12-06 WO PCT/US2019/065069 patent/WO2020118252A1/en not_active Ceased
- 2019-12-06 MX MX2021005075A patent/MX2021005075A/es unknown
- 2019-12-06 KR KR1020217020796A patent/KR20210100145A/ko not_active Withdrawn
- 2019-12-06 AU AU2019395100A patent/AU2019395100A1/en not_active Abandoned
- 2019-12-06 US US16/706,463 patent/US20200281949A1/en not_active Abandoned
- 2019-12-06 JP JP2021531722A patent/JP2022510410A/ja active Pending
- 2019-12-06 CA CA3120850A patent/CA3120850A1/en active Pending
- 2019-12-06 EP EP19893131.3A patent/EP3891294A4/en not_active Withdrawn
-
2021
- 2021-12-10 US US17/547,799 patent/US20220339172A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017534248A (ja) * | 2014-08-25 | 2017-11-24 | ザ ジョンズ ホプキンズ ユニヴァーシティー | 前立腺がん治療に関する方法及び組成物 |
| JP2018517686A (ja) * | 2015-05-18 | 2018-07-05 | トレロ ファーマシューティカルズ, インコーポレイテッド | バイオアベイラビリティが高いアルボシジブプロドラッグ |
Non-Patent Citations (4)
| Title |
|---|
| BJU INT, vol. 113, JPN6023043528, 2014, pages 82 - 89, ISSN: 0005330401 * |
| CANCER RES, vol. 72, JPN6023043529, 2012, pages 8, ISSN: 0005330402 * |
| MOL CANCER THER, vol. 5, no. 5, JPN6023043531, 2006, pages 1216 - 1226, ISSN: 0005178025 * |
| MOL ENDOCRINOL, vol. 24, JPN6023043530, 2010, pages 2267 - 2280, ISSN: 0005330403 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20220339172A1 (en) | 2022-10-27 |
| AU2019395100A1 (en) | 2021-06-03 |
| EP3891294A1 (en) | 2021-10-13 |
| EP3891294A4 (en) | 2022-09-07 |
| CN113164500A (zh) | 2021-07-23 |
| KR20210100145A (ko) | 2021-08-13 |
| MX2021005075A (es) | 2021-07-15 |
| US20200281949A1 (en) | 2020-09-10 |
| CA3120850A1 (en) | 2020-06-11 |
| WO2020118252A1 (en) | 2020-06-11 |
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