JP2022508523A5 - - Google Patents
Info
- Publication number
- JP2022508523A5 JP2022508523A5 JP2021542086A JP2021542086A JP2022508523A5 JP 2022508523 A5 JP2022508523 A5 JP 2022508523A5 JP 2021542086 A JP2021542086 A JP 2021542086A JP 2021542086 A JP2021542086 A JP 2021542086A JP 2022508523 A5 JP2022508523 A5 JP 2022508523A5
- Authority
- JP
- Japan
- Prior art keywords
- pyridine
- thieno
- trifluoromethyl
- methylcarbamoyl
- piperidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862739405P | 2018-10-01 | 2018-10-01 | |
| US62/739,405 | 2018-10-01 | ||
| PCT/US2019/054085 WO2020072504A1 (en) | 2018-10-01 | 2019-10-01 | Thieno[3,2-b]pyridine derivatives as udp glycosyltransferase inhibitors and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022508523A JP2022508523A (ja) | 2022-01-19 |
| JP2022508523A5 true JP2022508523A5 (cg-RX-API-DMAC7.html) | 2022-09-07 |
| JP7545979B2 JP7545979B2 (ja) | 2024-09-05 |
Family
ID=68296740
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021542086A Active JP7545979B2 (ja) | 2018-10-01 | 2019-10-01 | ＵＤＰグリコシルトランスフェラーゼ阻害剤としてのチエノ［３，２－ｂ］ピリジン誘導体および使用の方法 |
Country Status (15)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4294798A1 (en) * | 2021-02-19 | 2023-12-27 | Kalvista Pharmaceuticals Limited | Factor xiia inhibitors |
| EP4483954A1 (en) * | 2023-06-29 | 2025-01-01 | Masarykova Univerzita | Substituted thieno [3,2-b]pyridines as inhibitors of protein kinases |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3763156A (en) * | 1970-01-28 | 1973-10-02 | Boehringer Sohn Ingelheim | 2-heterocyclic amino-4-morpholinothieno(3,2-d)pyrimidines |
| BR0012984A (pt) | 1999-08-04 | 2002-07-16 | Millennium Pharm Inc | Método para tratar um estado associado com o mc4-r em um mamìfero, composto de ligação ao mc4-r, e, composição farmacêutica |
| US7375125B2 (en) * | 1999-08-04 | 2008-05-20 | Ore Pharmaceuticals, Inc. | Melanocortin-4 receptor binding compounds and methods of use thereof |
| FR2821356A1 (fr) * | 2001-02-23 | 2002-08-30 | Cerep | Nouveaux derives d'arylcarbamates et d'arylurees, preparations et utilisations |
| EP2215094B1 (en) * | 2007-11-15 | 2016-01-27 | YM BioSciences Australia Pty Ltd | N-containing heterocyclic compounds |
| US8450363B2 (en) * | 2009-02-06 | 2013-05-28 | Elan Pharmaceuticals, Inc. | Inhibitors of Jun N-terminal kinase |
| CN103458970A (zh) * | 2011-03-07 | 2013-12-18 | 泰莱托恩基金会 | Tfeb磷酸化抑制剂及其应用 |
| CA2973949C (en) * | 2015-01-16 | 2023-07-11 | The General Hospital Corporation | Compounds for improving mrna splicing |
| SG11201804901WA (en) * | 2015-12-22 | 2018-07-30 | SHY Therapeutics LLC | Compounds for the treatment of cancer and inflammatory disease |
| KR102530515B1 (ko) * | 2016-05-05 | 2023-05-09 | 비알 - 알&디 인베스트먼츠, 에스.에이. | 치환된 이미다조[1,2-b]피리다진, 치환된 이미다조[1,5-b]피리다진, 관련 화합물, 및 의학적 장애의 치료에서의 그의 용도 |
| US20190134005A1 (en) | 2016-06-10 | 2019-05-09 | Biomarin Pharmaceutical Inc. | Ceramide galactosyltransferase inhibitors for the treatment of disease |
| MX385576B (es) * | 2016-11-02 | 2025-03-18 | Janssen Pharmaceutica Nv | Derivados de [1,2,4]triazol[1,5-a]pirimidina como inhibidores de pde2 |
| WO2018118838A1 (en) * | 2016-12-20 | 2018-06-28 | Biomarin Pharmaceutical Inc. | Ceramide galactosyltransferase inhibitors for the treatment of disease |
| BR112019023109A2 (pt) * | 2017-05-04 | 2020-05-26 | Glenmark Pharmaceuticals S.A. | Composto, composição farmacêutica e método para tratar uma doença, distúrbio, síndrome ou afecção mediada por nadph oxidase em um indivíduo |
| EA201992780A1 (ru) * | 2017-06-21 | 2020-06-02 | ШАЙ ТЕРАПЬЮТИКС ЭлЭлСи | Соединения, которые взаимодействуют с суперсемейством ras, для лечения рака, воспалительных заболеваний, ras-опатий и фиброзного заболевания |
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2019
- 2019-10-01 EP EP19791011.0A patent/EP3861000A1/en active Pending
- 2019-10-01 CN CN201980076707.1A patent/CN113423711B/zh active Active
- 2019-10-01 IL IL281811A patent/IL281811B2/en unknown
- 2019-10-01 JP JP2021542086A patent/JP7545979B2/ja active Active
- 2019-10-01 MX MX2021003794A patent/MX2021003794A/es unknown
- 2019-10-01 MA MA53043A patent/MA53043B2/fr unknown
- 2019-10-01 TW TW108135781A patent/TWI821426B/zh active
- 2019-10-01 CA CA3114722A patent/CA3114722A1/en active Pending
- 2019-10-01 AU AU2019355870A patent/AU2019355870B2/en active Active
- 2019-10-01 US US16/590,027 patent/US11098056B2/en active Active
- 2019-10-01 BR BR112021005914-8A patent/BR112021005914A2/pt unknown
- 2019-10-01 WO PCT/US2019/054085 patent/WO2020072504A1/en not_active Ceased
- 2019-10-01 KR KR1020217013167A patent/KR102903997B1/ko active Active
- 2019-10-01 SG SG11202102987VA patent/SG11202102987VA/en unknown
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2021
- 2021-04-29 CO CONC2021/0005738A patent/CO2021005738A2/es unknown