JP2022505022A5 - - Google Patents
Info
- Publication number
- JP2022505022A5 JP2022505022A5 JP2021518633A JP2021518633A JP2022505022A5 JP 2022505022 A5 JP2022505022 A5 JP 2022505022A5 JP 2021518633 A JP2021518633 A JP 2021518633A JP 2021518633 A JP2021518633 A JP 2021518633A JP 2022505022 A5 JP2022505022 A5 JP 2022505022A5
- Authority
- JP
- Japan
- Prior art keywords
- substance
- pharmaceutical
- alpha
- substance used
- emitting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024174991A JP2025013822A (ja) | 2018-11-01 | 2024-10-04 | 腫瘍内アルファ放射体放射と細胞内病原体に対する細胞質プラズマセンサーの活性化 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862753930P | 2018-11-01 | 2018-11-01 | |
| US62/753,930 | 2018-11-01 | ||
| PCT/IB2019/059331 WO2020089819A1 (en) | 2018-11-01 | 2019-10-31 | Intratumoral alpha-emitter radiation and activation of cytoplasmatic sensors for intracellular pathogen |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024174991A Division JP2025013822A (ja) | 2018-11-01 | 2024-10-04 | 腫瘍内アルファ放射体放射と細胞内病原体に対する細胞質プラズマセンサーの活性化 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022505022A JP2022505022A (ja) | 2022-01-14 |
| JP2022505022A5 true JP2022505022A5 (https=) | 2022-10-19 |
Family
ID=70464034
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021518633A Pending JP2022505022A (ja) | 2018-11-01 | 2019-10-31 | 腫瘍内アルファ放射体放射と細胞内病原体に対する細胞質プラズマセンサーの活性化 |
| JP2024174991A Pending JP2025013822A (ja) | 2018-11-01 | 2024-10-04 | 腫瘍内アルファ放射体放射と細胞内病原体に対する細胞質プラズマセンサーの活性化 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024174991A Pending JP2025013822A (ja) | 2018-11-01 | 2024-10-04 | 腫瘍内アルファ放射体放射と細胞内病原体に対する細胞質プラズマセンサーの活性化 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US12594291B2 (https=) |
| EP (2) | EP4603098A3 (https=) |
| JP (2) | JP2022505022A (https=) |
| KR (1) | KR20210087949A (https=) |
| CN (2) | CN117338800A (https=) |
| AU (3) | AU2019370892B2 (https=) |
| CA (1) | CA3114299A1 (https=) |
| ES (1) | ES3035872T3 (https=) |
| HR (1) | HRP20250846T1 (https=) |
| HU (1) | HUE072799T2 (https=) |
| PL (1) | PL3873598T3 (https=) |
| SG (1) | SG11202102627PA (https=) |
| WO (1) | WO2020089819A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10350431B2 (en) | 2011-04-28 | 2019-07-16 | Gt Medical Technologies, Inc. | Customizable radioactive carriers and loading system |
| US9821174B1 (en) | 2015-02-06 | 2017-11-21 | Gammatile Llc | Radioactive implant planning system and placement guide system |
| US10888710B1 (en) | 2016-11-29 | 2021-01-12 | Gt Medical Technologies, Inc. | Transparent loading apparatus |
| CA3192409A1 (en) * | 2020-09-15 | 2022-03-24 | Jan A. Alfheim | Preparations of radium-224 and progenies for use in radionuclide therapy in combination with dna repair inhibitors |
| AU2021400142B2 (en) | 2020-12-16 | 2024-11-21 | Alpha Tau Medical Ltd. | Diffusing alpha-emitters radiation therapy with enhanced beta treatment |
| CN113230400A (zh) * | 2021-03-11 | 2021-08-10 | 上海交通大学 | 一种基于表观遗传调控的金纳米团簇放疗增敏组装体及其制备和应用 |
| US20220395702A1 (en) * | 2021-06-10 | 2022-12-15 | Alpha Tau Medical Ltd. | Diffusing alpha-emitter radiation therapy for glioblastoma |
| US12076581B2 (en) | 2021-06-10 | 2024-09-03 | Alpha Tau Medical Ltd. | Diffusing alpha-emitter radiation therapy for glioblastoma |
| US12064643B2 (en) | 2021-06-10 | 2024-08-20 | Alpha Tau Medical Ltd. | Diffusing alpha-emitter radiation therapy for breast cancer |
| US20220395703A1 (en) * | 2021-06-10 | 2022-12-15 | Alpha Tau Medical Ltd. | Activity levels for diffusing alpha-emitter radiation therapy |
| US12070620B2 (en) | 2021-06-10 | 2024-08-27 | Alpha Tau Medical Ltd. | Activity levels for diffusing alpha-emitter radiation therapy |
| US20220395701A1 (en) * | 2021-06-10 | 2022-12-15 | Alpha Tau Medical Ltd. | Diffusing alpha-emitter radiation therapy for pancreatic cancer |
| US12076583B2 (en) | 2021-06-10 | 2024-09-03 | Alpha Tau Medical Ltd. | Diffusing alpha-emitter radiation therapy for melanoma |
| US12042668B2 (en) | 2021-06-10 | 2024-07-23 | Alpha Tau Medical Ltd. | Diffusing alpha-emitter radiation therapy for squamous cell carcinoma |
| US11964168B2 (en) | 2021-06-10 | 2024-04-23 | Alpha Tau Medical Ltd. | Diffusing alpha-emitter radiation therapy for prostate cancer |
| US12070621B2 (en) | 2021-06-10 | 2024-08-27 | Alpha Tau Medical Ltd. | Diffusing alpha-emitter radiation therapy for pancreatic cancer |
| US12076582B2 (en) | 2021-06-10 | 2024-09-03 | Alpha Tau Medical Ltd. | Diffusing alpha-emitter radiation therapy for colorectal cancer |
| IL309328A (en) * | 2021-06-20 | 2024-02-01 | Alpha Tau Medical Ltd | Irradiation by intratumoral alpha emitters in combination with vascular inhibitors |
| IL309327A (en) * | 2021-06-20 | 2024-02-01 | Alpha Tau Medical Ltd | Irradiation by intratumoral alpha emitters in combination with immune checkpoint regulators |
| US12053644B2 (en) | 2021-12-30 | 2024-08-06 | Gt Medical Technologies, Inc. | Radiation shielding apparatus for implantable radioactive seeds |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6248057B1 (en) | 1998-07-28 | 2001-06-19 | Innerdyne, Inc. | Absorbable brachytherapy and chemotherapy delivery devices and methods |
| ATE437226T1 (de) | 2000-01-31 | 2009-08-15 | Yissum Res Dev Co | Selektiv-abtöten von zellen durch aktivierung der doppelsträngiges rns abhängigen proteinkinase - pkr |
| US20030153083A1 (en) | 2000-01-31 | 2003-08-14 | Alexei Shir | Selective killing of cells by activation of double-stranded rna dependent protein kniase-pkr |
| GB0011903D0 (en) | 2000-05-18 | 2000-07-05 | Astrazeneca Ab | Combination chemotherapy |
| RU2284818C2 (ru) | 2001-05-10 | 2006-10-10 | Анормед, Инк. | Комбинированная химиотерапия |
| AU2003226408B2 (en) * | 2002-04-15 | 2007-06-14 | Sloan-Kettering Institute For Cancer Research | Combination therapy for the treatment of cancer |
| US7927792B2 (en) | 2002-11-18 | 2011-04-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Targeted double stranded RNA mediated cell killing |
| ES2294496T3 (es) | 2003-04-30 | 2008-04-01 | Ramot At Tel Aviv University Ltd. | Metodo y dispositivo para radioterapia. |
| US20050013812A1 (en) * | 2003-07-14 | 2005-01-20 | Dow Steven W. | Vaccines using pattern recognition receptor-ligand:lipid complexes |
| GB0423565D0 (en) | 2004-10-22 | 2004-11-24 | Algeta As | Formulation |
| US7834064B2 (en) | 2005-01-03 | 2010-11-16 | Andres Mario Salazar | Clinical method for the immunomodulatory and vaccine adjuvant use of poly-ICLC and other dsRNAs |
| CA2615589A1 (en) | 2005-07-26 | 2007-02-01 | Ramot At Tel Aviv University Ltd. | A radioactive surface source and a method for producing the same |
| US20080124366A1 (en) | 2006-08-06 | 2008-05-29 | Ohlfest John R | Methods and Compositions for Treating Tumors |
| US20090088401A1 (en) | 2007-09-27 | 2009-04-02 | Andres Salazar | In-situ cancer autovaccination with intratumoral stabilized dsRNA viral mimic |
| EP2247308A4 (en) | 2008-01-10 | 2012-04-18 | Nventa Biopharmaceuticals Corp | AUXILIARY COMPOSITIONS WITH POLY-IC AND A CATIONIC POLYMER |
| US20090234628A1 (en) * | 2008-03-14 | 2009-09-17 | Siemens Medical Solutions Usa, Inc. | Prediction of complete response given treatment data |
| US20100015042A1 (en) * | 2008-07-03 | 2010-01-21 | Ramot At Tel Aviv University Ltd. | Combine radiation therapy and chemotherapy for treating cancer |
| US8821364B2 (en) | 2008-09-02 | 2014-09-02 | Battelle Memorial Institute | Brachytherapy seed with fast dissolving matrix for optimal delivery of radionuclides to cancer tissue |
| US9006406B2 (en) | 2008-12-22 | 2015-04-14 | Alexander Levitzki | EGFR-homing double-stranded RNA vector for systemic cancer treatment |
| WO2011024172A2 (en) | 2009-08-27 | 2011-03-03 | Technion Research & Development Foundation Ltd. | Liposomal compositions and uses of same |
| CA2787260A1 (en) * | 2010-01-18 | 2011-07-21 | Zhi-Min Yuan | Methods and compositions for nanoparticle-mediated cancer cell-targeted delivery |
| JP5860874B2 (ja) | 2010-06-22 | 2016-02-16 | デエヌア・テラプーティックＤｎａｔｈｅｒａｐｅｕｔｉｃｓ | 核酸コンジュゲートのためのエンドソーム溶解剤を用いた最適化ｉｎｖｉｖｏ送達システム |
| CN104411331B (zh) | 2012-01-13 | 2018-08-21 | 哈佛学院董事会 | 在结构聚合装置中tlr激动剂的控制传递 |
| US10421971B2 (en) | 2014-01-15 | 2019-09-24 | The University Of Chicago | Anti-tumor therapy |
| EP4245376A3 (en) * | 2014-10-14 | 2023-12-13 | Novartis AG | Antibody molecules to pd-l1 and uses thereof |
| WO2017025496A1 (en) * | 2015-08-12 | 2017-02-16 | Bayer Pharma Aktiengesellschaft | Pharmaceutical combination for the treatment of cancer |
| CN105031648A (zh) * | 2015-08-25 | 2015-11-11 | 徐州医学院 | 新型靶向纳米粒子及其制备方法和用途 |
| EP3319587B1 (en) | 2015-11-17 | 2019-08-21 | Bioncotech Therapeutics, S.L | Novel pharmaceutical composition comprising particles comprising a complex of a double-stranded polyribonucleotide and a polyalkyleneimine |
| WO2017173101A1 (en) * | 2016-03-30 | 2017-10-05 | Virginia Commonwealth University | Combination therapy for neuroblastoma using mda-7/il-24 with therapeutic agents |
| US11633506B2 (en) | 2016-07-18 | 2023-04-25 | Wisconsin Alumni Research Foundation | Using targeted radiotherapy (TRT) to drive anti-tumor immune response to immunotherapies |
| IL264557B2 (en) | 2016-08-02 | 2024-01-01 | Harvard College | Biological agents for regulating immune responses |
| AU2017321609C1 (en) * | 2016-08-30 | 2023-11-09 | Dana-Farber Cancer Institute, Inc. | Drug delivery compositions and uses thereof |
| JP7096249B2 (ja) | 2016-09-04 | 2022-07-05 | ターグイミューン セラピューティクス アーゲー | ｄｓＲＮＡを標的化するためのキメラタンパク質 |
| EP3321362A1 (en) * | 2016-11-10 | 2018-05-16 | Centre Leon Berard | Tlr3 agonist for use for inducing apoptosis in senescent cancer cells |
| US11642346B2 (en) * | 2017-03-31 | 2023-05-09 | Epizyme, Inc. | Combination therapy for treating cancer |
| WO2018185135A1 (en) * | 2017-04-05 | 2018-10-11 | Boehringer Ingelheim International Gmbh | Anticancer combination therapy |
| CN120643844A (zh) | 2017-05-11 | 2025-09-16 | 阿尔法陶医疗有限公司 | 用于近距离放射治疗装置的聚合物涂层 |
| US10849921B2 (en) | 2017-05-17 | 2020-12-01 | Bioncotech Therapeutics Sl | Pharmaceutical composition comprising particles comprising a complex of a double-stranded polyribonucleotide and a polyalkyleneimine |
| IL273195B2 (en) | 2017-09-27 | 2024-04-01 | Targimmune Therapeutics Ag | Castration-resistant prostate cancer |
| WO2019173456A1 (en) * | 2018-03-06 | 2019-09-12 | Board Of Regents, The University Of Texas System | Replication stress response biomarkers for immunotherapy response |
| KR20240172761A (ko) | 2018-03-08 | 2024-12-10 | 알파 타우 메디컬 리미티드 | 방사선 요법 시드 및 어플리케이터 |
| EP3762417A1 (en) | 2018-03-08 | 2021-01-13 | TargImmune Therapeutics AG | A recombinant protein comprising a double stranded rna binding domain |
| WO2019193464A1 (en) | 2018-04-02 | 2019-10-10 | Alpha Tau Medical Ltd. | Controlled release of radionuclides |
| EP3856256A1 (en) * | 2018-09-26 | 2021-08-04 | Ascendis Pharma A/S | Novel hydrogel conjugates |
| KR20210146952A (ko) | 2019-04-03 | 2021-12-06 | 타르그이뮨 테라퓨틱스 아게 | 암의 치료를 위한 면역요법 |
| JP7372706B2 (ja) | 2019-10-10 | 2023-11-01 | アルファ タウ メディカル リミテッド | 放射線治療源の湿式調製 |
-
2019
- 2019-10-31 CN CN202311449613.9A patent/CN117338800A/zh active Pending
- 2019-10-31 KR KR1020217013680A patent/KR20210087949A/ko not_active Ceased
- 2019-10-31 PL PL19879337.4T patent/PL3873598T3/pl unknown
- 2019-10-31 US US17/288,926 patent/US12594291B2/en active Active
- 2019-10-31 ES ES19879337T patent/ES3035872T3/es active Active
- 2019-10-31 JP JP2021518633A patent/JP2022505022A/ja active Pending
- 2019-10-31 HR HRP20250846TT patent/HRP20250846T1/hr unknown
- 2019-10-31 CA CA3114299A patent/CA3114299A1/en active Pending
- 2019-10-31 WO PCT/IB2019/059331 patent/WO2020089819A1/en not_active Ceased
- 2019-10-31 EP EP25179481.4A patent/EP4603098A3/en active Pending
- 2019-10-31 HU HUE19879337A patent/HUE072799T2/hu unknown
- 2019-10-31 CN CN201980070966.3A patent/CN112912137B/zh active Active
- 2019-10-31 AU AU2019370892A patent/AU2019370892B2/en active Active
- 2019-10-31 SG SG11202102627PA patent/SG11202102627PA/en unknown
- 2019-10-31 EP EP19879337.4A patent/EP3873598B1/en active Active
-
2023
- 2023-07-26 AU AU2023208136A patent/AU2023208136B2/en active Active
-
2024
- 2024-10-04 JP JP2024174991A patent/JP2025013822A/ja active Pending
-
2025
- 2025-09-11 AU AU2025230719A patent/AU2025230719A1/en active Pending
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