JP2010535084A5 - - Google Patents
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- Publication number
- JP2010535084A5 JP2010535084A5 JP2010520162A JP2010520162A JP2010535084A5 JP 2010535084 A5 JP2010535084 A5 JP 2010535084A5 JP 2010520162 A JP2010520162 A JP 2010520162A JP 2010520162 A JP2010520162 A JP 2010520162A JP 2010535084 A5 JP2010535084 A5 JP 2010535084A5
- Authority
- JP
- Japan
- Prior art keywords
- agent
- delivery vehicle
- internal
- intracorporeal
- nanostructure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003795 chemical substances by application Substances 0.000 claims description 39
- 239000002086 nanomaterial Substances 0.000 claims description 20
- 239000003814 drug Substances 0.000 claims description 16
- 230000005855 radiation Effects 0.000 claims description 14
- 238000012377 drug delivery Methods 0.000 claims description 12
- 239000002245 particle Substances 0.000 claims description 9
- 229940124597 therapeutic agent Drugs 0.000 claims description 9
- 239000002872 contrast media Substances 0.000 claims description 7
- 229940079593 drug Drugs 0.000 claims description 7
- 230000004913 activation Effects 0.000 claims description 5
- 238000001727 in vivo Methods 0.000 claims description 5
- 239000002105 nanoparticle Substances 0.000 claims description 4
- 206010028980 Neoplasm Diseases 0.000 claims description 2
- 239000000427 antigen Substances 0.000 claims description 2
- 102000036639 antigens Human genes 0.000 claims description 2
- 108091007433 antigens Proteins 0.000 claims description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 2
- 239000010931 gold Substances 0.000 claims description 2
- 229910052737 gold Inorganic materials 0.000 claims description 2
- 239000011248 coating agent Substances 0.000 claims 12
- 238000000576 coating method Methods 0.000 claims 12
- 239000010410 layer Substances 0.000 claims 5
- 230000015556 catabolic process Effects 0.000 claims 3
- 238000006731 degradation reaction Methods 0.000 claims 3
- 239000013598 vector Substances 0.000 claims 2
- 239000011247 coating layer Substances 0.000 claims 1
- 230000007774 longterm Effects 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 230000001681 protective effect Effects 0.000 claims 1
- 238000011144 upstream manufacturing Methods 0.000 claims 1
- 238000003384 imaging method Methods 0.000 description 4
- 230000002708 enhancing effect Effects 0.000 description 3
- 239000002246 antineoplastic agent Substances 0.000 description 2
- 239000003623 enhancer Substances 0.000 description 2
- 150000001768 cations Chemical class 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95277307P | 2007-07-30 | 2007-07-30 | |
| US60/952,773 | 2007-07-30 | ||
| PCT/US2008/071653 WO2009018383A1 (en) | 2007-07-30 | 2008-07-30 | Systems and methods for particle radiation enhanced delivery of therapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010535084A JP2010535084A (ja) | 2010-11-18 |
| JP2010535084A5 true JP2010535084A5 (https=) | 2013-04-25 |
| JP5331116B2 JP5331116B2 (ja) | 2013-10-30 |
Family
ID=40304856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010520162A Expired - Fee Related JP5331116B2 (ja) | 2007-07-30 | 2008-07-30 | 粒子放射線で増強された治療を供給するシステム及び方法 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP2173430A4 (https=) |
| JP (1) | JP5331116B2 (https=) |
| AU (1) | AU2008282215B2 (https=) |
| CA (1) | CA2695985C (https=) |
| WO (1) | WO2009018383A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3136594B2 (ja) | 1990-02-28 | 2001-02-19 | ソニー株式会社 | 非水電解液二次電池 |
| US8669533B2 (en) | 2009-10-01 | 2014-03-11 | Vladimir Bashkirov | Ion induced impact ionization detector and uses thereof |
| JP2023512214A (ja) | 2020-01-28 | 2023-03-24 | リフレクション メディカル， インコーポレイテッド | 放射性核種および外部ビーム放射線療法の共同最適化 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4870287A (en) | 1988-03-03 | 1989-09-26 | Loma Linda University Medical Center | Multi-station proton beam therapy system |
| US4917344A (en) | 1988-04-07 | 1990-04-17 | Loma Linda University Medical Center | Roller-supported, modular, isocentric gantry and method of assembly |
| US5117829A (en) | 1989-03-31 | 1992-06-02 | Loma Linda University Medical Center | Patient alignment system and procedure for radiation treatment |
| GB9020075D0 (en) * | 1990-09-14 | 1990-10-24 | Filler Aaron G | Contrast agents for magnetic resonance imaging of axonal transport |
| US5825845A (en) | 1996-10-28 | 1998-10-20 | Loma Linda University Medical Center | Proton beam digital imaging system |
| US6645464B1 (en) * | 1998-07-30 | 2003-11-11 | James F. Hainfeld | Loading metal particles into cell membrane vesicles and metal particular use for imaging and therapy |
| US6159443A (en) * | 1999-04-29 | 2000-12-12 | Vanderbilt University | X-ray guided drug delivery |
| US20050090732A1 (en) * | 2003-10-28 | 2005-04-28 | Triton Biosystems, Inc. | Therapy via targeted delivery of nanoscale particles |
| RU2006144851A (ru) * | 2004-06-15 | 2008-06-20 | Бакстер Интернэшнл Инк. (Us) | Применение терапевтических средств ex-vivo в виде твердых микрочастиц |
| US20070009441A1 (en) * | 2004-07-08 | 2007-01-11 | Molecular Therapeutics, Inc. | Biodegradable nanoparticles |
-
2008
- 2008-07-30 CA CA2695985A patent/CA2695985C/en active Active
- 2008-07-30 WO PCT/US2008/071653 patent/WO2009018383A1/en not_active Ceased
- 2008-07-30 EP EP08826721A patent/EP2173430A4/en not_active Withdrawn
- 2008-07-30 JP JP2010520162A patent/JP5331116B2/ja not_active Expired - Fee Related
- 2008-07-30 AU AU2008282215A patent/AU2008282215B2/en not_active Ceased
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