CA2695985C - Systems and methods for particle radiation enhanced delivery of therapy - Google Patents

Systems and methods for particle radiation enhanced delivery of therapy Download PDF

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Publication number
CA2695985C
CA2695985C CA2695985A CA2695985A CA2695985C CA 2695985 C CA2695985 C CA 2695985C CA 2695985 A CA2695985 A CA 2695985A CA 2695985 A CA2695985 A CA 2695985A CA 2695985 C CA2695985 C CA 2695985C
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CA
Canada
Prior art keywords
delivery vehicle
vivo agent
vivo
agent delivery
nanostructure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2695985A
Other languages
English (en)
French (fr)
Other versions
CA2695985A1 (en
Inventor
Reinhard Schulte
Gilmer Valdes-Diaz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Loma Linda University
Original Assignee
Loma Linda University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Loma Linda University filed Critical Loma Linda University
Publication of CA2695985A1 publication Critical patent/CA2695985A1/en
Application granted granted Critical
Publication of CA2695985C publication Critical patent/CA2695985C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1087—Ions; Protons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Radiation-Therapy Devices (AREA)
CA2695985A 2007-07-30 2008-07-30 Systems and methods for particle radiation enhanced delivery of therapy Active CA2695985C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95277307P 2007-07-30 2007-07-30
US60/952,773 2007-07-30
PCT/US2008/071653 WO2009018383A1 (en) 2007-07-30 2008-07-30 Systems and methods for particle radiation enhanced delivery of therapy

Publications (2)

Publication Number Publication Date
CA2695985A1 CA2695985A1 (en) 2009-02-05
CA2695985C true CA2695985C (en) 2016-06-28

Family

ID=40304856

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2695985A Active CA2695985C (en) 2007-07-30 2008-07-30 Systems and methods for particle radiation enhanced delivery of therapy

Country Status (5)

Country Link
EP (1) EP2173430A4 (https=)
JP (1) JP5331116B2 (https=)
AU (1) AU2008282215B2 (https=)
CA (1) CA2695985C (https=)
WO (1) WO2009018383A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3136594B2 (ja) 1990-02-28 2001-02-19 ソニー株式会社 非水電解液二次電池
US8669533B2 (en) 2009-10-01 2014-03-11 Vladimir Bashkirov Ion induced impact ionization detector and uses thereof
JP2023512214A (ja) 2020-01-28 2023-03-24 リフレクション メディカル， インコーポレイテッド 放射性核種および外部ビーム放射線療法の共同最適化

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870287A (en) 1988-03-03 1989-09-26 Loma Linda University Medical Center Multi-station proton beam therapy system
US4917344A (en) 1988-04-07 1990-04-17 Loma Linda University Medical Center Roller-supported, modular, isocentric gantry and method of assembly
US5117829A (en) 1989-03-31 1992-06-02 Loma Linda University Medical Center Patient alignment system and procedure for radiation treatment
GB9020075D0 (en) * 1990-09-14 1990-10-24 Filler Aaron G Contrast agents for magnetic resonance imaging of axonal transport
US5825845A (en) 1996-10-28 1998-10-20 Loma Linda University Medical Center Proton beam digital imaging system
US6645464B1 (en) * 1998-07-30 2003-11-11 James F. Hainfeld Loading metal particles into cell membrane vesicles and metal particular use for imaging and therapy
US6159443A (en) * 1999-04-29 2000-12-12 Vanderbilt University X-ray guided drug delivery
US20050090732A1 (en) * 2003-10-28 2005-04-28 Triton Biosystems, Inc. Therapy via targeted delivery of nanoscale particles
RU2006144851A (ru) * 2004-06-15 2008-06-20 Бакстер Интернэшнл Инк. (Us) Применение терапевтических средств ex-vivo в виде твердых микрочастиц
US20070009441A1 (en) * 2004-07-08 2007-01-11 Molecular Therapeutics, Inc. Biodegradable nanoparticles

Also Published As

Publication number Publication date
CA2695985A1 (en) 2009-02-05
AU2008282215A1 (en) 2009-02-05
JP5331116B2 (ja) 2013-10-30
EP2173430A1 (en) 2010-04-14
JP2010535084A (ja) 2010-11-18
AU2008282215B2 (en) 2014-05-29
WO2009018383A1 (en) 2009-02-05
EP2173430A4 (en) 2012-11-21

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Effective date: 20130729