|
US447475A
(en)
|
|
1891-03-03 |
|
pomerof |
|
US4188373A
(en)
|
1976-02-26 |
1980-02-12 |
Cooper Laboratories, Inc. |
Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
|
|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
|
US4478822A
(en)
|
1983-05-16 |
1984-10-23 |
Merck & Co., Inc. |
Drug delivery system utilizing thermosetting gels
|
|
US4474751A
(en)
|
1983-05-16 |
1984-10-02 |
Merck & Co., Inc. |
Ophthalmic drug delivery system utilizing thermosetting gels
|
|
US5346703A
(en)
|
1990-08-07 |
1994-09-13 |
Mediventures, Inc. |
Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels
|
|
WO2000007603A2
(en)
|
1998-08-04 |
2000-02-17 |
Madash Llp |
End modified thermal responsive hydrogels
|
|
US6761824B2
(en)
|
2000-08-17 |
2004-07-13 |
Reeve Lorraine E |
Process for the fractionation of polymers
|
|
WO2009009737A1
(en)
*
|
2007-07-12 |
2009-01-15 |
Neurosci, Inc. |
Sustained release formulation of active pharmaceuticals in a lipid based sustained release
|
|
EP2732819B1
(en)
|
2008-02-07 |
2019-10-16 |
Massachusetts Eye & Ear Infirmary |
Compounds that enhance Atoh-1 expression
|
|
AR087107A1
(es)
|
2011-07-27 |
2014-02-12 |
Lilly Co Eli |
Compuesto inhibidor de la señalizacion de la trayectoria notch
|
|
EP2606884A1
(en)
|
2011-12-21 |
2013-06-26 |
Ecole Polytechnique Fédérale de Lausanne (EPFL) |
Inhibitors of notch signaling pathway and use thereof in treatment of cancers
|
|
EP2854809B1
(en)
|
2012-06-01 |
2017-12-06 |
Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut e.V. (FLI) |
Inhibitors of the notch signalling pathway and secretion for use in medicine
|
|
CA2883896C
(en)
|
2012-09-07 |
2023-03-07 |
Massachusetts Eye & Ear Infirmary |
Treating hearing loss
|
|
WO2014047370A1
(en)
|
2012-09-21 |
2014-03-27 |
Bristol-Myers Squibb Company |
Fluoroalkyl dibenzodiazepinone compounds
|
|
WO2014047369A1
(en)
|
2012-09-21 |
2014-03-27 |
Bristol-Myers Squibb Company |
Substituted 1,5-benzodiazepinone compounds
|
|
TWI614238B
(zh)
|
2012-09-21 |
2018-02-11 |
必治妥美雅史谷比公司 |
雙（氟烷基）－１，４－苯并二氮呯酮化合物及其前藥
|
|
UA110688C2
(uk)
|
2012-09-21 |
2016-01-25 |
Пфайзер Інк. |
Біциклічні піридинони
|
|
WO2014047391A1
(en)
|
2012-09-21 |
2014-03-27 |
Bristol-Myers Squibb Company |
Prodrugs of 1,4-benzodiazepinone compounds
|
|
EP2897960B1
(en)
|
2012-09-21 |
2016-08-03 |
Bristol-Myers Squibb Company |
Tricyclic heterocyclic compounds as notch inhibitors
|
|
EP2897947B1
(en)
|
2012-09-21 |
2016-10-26 |
Bristol-Myers Squibb Company |
Alkyl, fluoroalkyl-1,4-benzodiazepinone compounds
|
|
WO2014047397A1
(en)
|
2012-09-21 |
2014-03-27 |
Bristol-Myers Squibb Company |
Fluoroalkyl and fluorocycloalkyl 1,4-benzodiazepinone compounds as notch|inhibitors
|
|
EP2897954B1
(en)
|
2012-09-21 |
2016-10-26 |
Bristol-Myers Squibb Company |
Fluoroalkyl-1,4-benzodiazepinone compounds
|
|
US9572815B2
(en)
|
2013-03-15 |
2017-02-21 |
St. Jude Children's Research Hospital |
Methods and compositions of p27KIP1 transcriptional modulators
|
|
CN103169649A
(zh)
*
|
2013-04-11 |
2013-06-26 |
中国人民解放军总医院 |
温度和离子双重敏感型原位凝胶鼻腔给药系统
|
|
WO2016022776A2
(en)
|
2014-08-06 |
2016-02-11 |
Massachusetts Eye And Ear Infirmary |
Increasing atoh1 life to drive sensorineural hair cell differentiantion
|
|
WO2016037016A1
(en)
*
|
2014-09-03 |
2016-03-10 |
The Brigham And Women's Hospital, Inc. |
Compositions, systems, and methods for generating inner ear hair cells for treatment of hearing loss
|
|
CN107075471A
(zh)
|
2014-10-08 |
2017-08-18 |
新加坡科技研究局 |
将干细胞分化为肝细胞谱系的方法
|
|
TWI625332B
(zh)
|
2015-07-07 |
2018-06-01 |
美國禮來大藥廠 |
刻痕（ｎｏｔｃｈ）路徑傳訊抑制化合物
|
|
KR102723605B1
(ko)
|
2015-12-22 |
2024-10-29 |
바스프 에스이 |
폴리에테르 블록 공중합체의 정제 방법
|
|
US10201540B2
(en)
*
|
2016-03-02 |
2019-02-12 |
Frequency Therapeutics, Inc. |
Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: I
|
|
US10213511B2
(en)
*
|
2016-03-02 |
2019-02-26 |
Frequency Therapeutics, Inc. |
Thermoreversible compositions for administration of therapeutic agents
|
|
JP7012715B2
(ja)
|
2016-06-27 |
2022-01-28 |
エフ．ホフマン－ラ ロシュ アーゲー |
γ－セクレターゼモジュレーターとしてのトリアゾロピリジン
|
|
EP3481829B1
(en)
|
2016-07-08 |
2021-04-07 |
H. Hoffnabb-La Roche Ag |
Fused pyrimidine derivatives
|
|
EP3484884B1
(en)
|
2016-07-14 |
2021-01-27 |
Hoffmann-La Roche AG |
Fused pyrimidine derivatives
|
|
AR109829A1
(es)
|
2016-09-29 |
2019-01-30 |
Hoffmann La Roche |
Derivados de piperidina puenteados
|
|
EP3523304B1
(en)
|
2016-10-04 |
2021-01-27 |
H. Hoffnabb-La Roche Ag |
Bicyclic heteroaryl derivatives
|
|
TWI757360B
(zh)
|
2016-11-08 |
2022-03-11 |
瑞士商赫孚孟拉羅股份公司 |
苯氧基三唑
|
|
MX390370B
(es)
|
2016-12-16 |
2025-03-20 |
Pipeline Therapeutics Inc |
Metodos para tratar la sinaptopatia coclear
|
|
CA3047730A1
(en)
|
2016-12-20 |
2018-06-28 |
Oligomerix, Inc. |
Quinazolinones that inhibit the formation of tau oligomers and their method of use
|
|
CA3047729A1
(en)
|
2016-12-20 |
2018-06-28 |
Oligomerix, Inc. |
Novel benzofuran, benzothiophene, and indole analogs that inhibit the formation of tau oligomers and their method of use
|
|
US10383881B2
(en)
|
2016-12-30 |
2019-08-20 |
Frequency Therapeutics, Inc. |
1,5-dihydro-2H-pyrrol-2-one compounds and methods of using same
|
|
US11066419B2
(en)
|
2016-12-30 |
2021-07-20 |
Frequency Therapeutics, Inc. |
1H-pyrrole-2,5-dione compounds and methods of using same
|
|
WO2018172997A1
(en)
|
2017-03-24 |
2018-09-27 |
Novartis Ag |
Isoxazole carboxamide compounds and uses thereof
|