JP2022503850A5 - - Google Patents

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Publication number
JP2022503850A5
JP2022503850A5 JP2021517420A JP2021517420A JP2022503850A5 JP 2022503850 A5 JP2022503850 A5 JP 2022503850A5 JP 2021517420 A JP2021517420 A JP 2021517420A JP 2021517420 A JP2021517420 A JP 2021517420A JP 2022503850 A5 JP2022503850 A5 JP 2022503850A5
Authority
JP
Japan
Prior art keywords
nucleic acid
nucleotides
construct according
acid portion
nucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021517420A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022503850A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2019/058221 external-priority patent/WO2020065602A2/en
Publication of JP2022503850A publication Critical patent/JP2022503850A/ja
Publication of JP2022503850A5 publication Critical patent/JP2022503850A5/ja
Pending legal-status Critical Current

Links

JP2021517420A 2018-09-28 2019-09-27 産物及び組成物 Pending JP2022503850A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862738222P 2018-09-28 2018-09-28
US62/738,222 2018-09-28
PCT/IB2019/058221 WO2020065602A2 (en) 2018-09-28 2019-09-27 Products and compositions

Publications (2)

Publication Number Publication Date
JP2022503850A JP2022503850A (ja) 2022-01-12
JP2022503850A5 true JP2022503850A5 (https=) 2022-09-28

Family

ID=69951906

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021517420A Pending JP2022503850A (ja) 2018-09-28 2019-09-27 産物及び組成物

Country Status (11)

Country Link
US (1) US20210371861A1 (https=)
EP (1) EP3856200A4 (https=)
JP (1) JP2022503850A (https=)
KR (1) KR20210093851A (https=)
CN (1) CN113164507A (https=)
AU (1) AU2019346148A1 (https=)
BR (1) BR112021005777A2 (https=)
CA (1) CA3110300A1 (https=)
IL (1) IL281684A (https=)
WO (1) WO2020065602A2 (https=)
ZA (1) ZA202101298B (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250000892A1 (en) * 2021-10-14 2025-01-02 Arizona Board Of Regents On Behalf Of Arizona State University Programmable delivery platforms for rna structures
WO2023069707A2 (en) * 2021-10-22 2023-04-27 Sirnaomics, Inc. Products and compositions
WO2023240249A1 (en) * 2022-06-11 2023-12-14 Sirnaomics, Inc. Products and compositions
WO2024059873A2 (en) * 2022-09-16 2024-03-21 Sirnaomics, Inc. Products and compositions
WO2024081922A1 (en) * 2022-10-14 2024-04-18 Arizona Board Of Regents On Behalf Of Arizona State University Modular rna delivery platforms and methods of their use
WO2024164001A2 (en) * 2023-02-03 2024-08-08 Sirnaomics, Inc. Products and compositions
WO2024216267A2 (en) * 2023-04-14 2024-10-17 Sirnaomics, Inc. Products and compositions
WO2024229229A2 (en) * 2023-05-02 2024-11-07 Sirnaomics, Inc. Products and compositions
TW202526017A (zh) 2023-09-14 2025-07-01 美商Ionis製藥公司 用於減少apociii表現的化合物及方法
WO2025064821A2 (en) 2023-09-21 2025-03-27 Ionis Pharmaceuticals, Inc. Compounds and methods for inhibiting lpa
WO2025259875A1 (en) * 2024-06-12 2025-12-18 Sirnaomics, Inc. Novel antibody oligonucleotide drug conjugates containing gemcitibine for pharmaceutical compositions and related methods of use and treatment

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1989307B1 (en) * 2006-02-08 2012-08-08 Quark Pharmaceuticals, Inc. NOVEL TANDEM siRNAS
US8252526B2 (en) * 2006-11-09 2012-08-28 Gradalis, Inc. ShRNA molecules and methods of use thereof
US20110251258A1 (en) * 2008-07-24 2011-10-13 Rxi Pharmaceuticals Corporation Rnai constructs and uses thereof
JP5529895B2 (ja) * 2009-02-04 2014-06-25 ソンギュングヮン ユニバーシティ ファウンデーション フォー コーポレート コラボレーション 細胞内の伝達能が増加した低分子干渉rna複合体
WO2010141511A2 (en) * 2009-06-01 2010-12-09 Halo-Bio Rnai Therapeutics, Inc. Polynucleotides for multivalent rna interference, compositions and methods of use thereof
WO2015164818A1 (en) * 2014-04-25 2015-10-29 Strike Bio, Inc. Multiple targeted rnai for the treatment of cancers
WO2016201301A1 (en) * 2015-06-12 2016-12-15 Alnylam Pharmaceuticals, Inc. Complement component c5 irna compositions and methods of use thereof
IL316159A (en) * 2015-06-15 2024-12-01 Mpeg La Llc Defined Oligonucleotide Multimers and Methods for Manufacture Thereof
US10689654B2 (en) * 2016-10-18 2020-06-23 Augusta University Research Institute, Inc. Bivalent siRNA chimeras and methods of use thereof
CN108342386B (zh) * 2017-01-22 2022-04-15 广州市锐博生物科技有限公司 一种多聚寡核酸分子及其在多靶标干扰中的应用
AU2018433363B2 (en) * 2018-07-20 2022-12-08 Guangzhou Ribobio Co., Ltd. Nucleic acid unit and polymeric nucleic acid and application thereof

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