JP2022500231A - Depアレイを有するマイクロ流体デバイス - Google Patents
Depアレイを有するマイクロ流体デバイス Download PDFInfo
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Abstract
Description
Claims (16)
- 複数のマイクロ流体チャネル及び複数の対応する誘電泳動(DEP)電極アレイを含むマイクロ流体デバイスであって、各マイクロ流体チャネルは、DEP電極アレイ上に流体を導くように配置され、前記デバイスは、交流電流源に前記デバイスを接続するための少なくとも1つの第1の接続点及び少なくとも1つの第2の接続点と、第1の導体を介して前記第1の接続点に接続された各DEP電極アレイの第1の入力と、第2の導体を介して前記第2の接続点に接続された各DEP電極アレイの第2の入力と、を更に含み、
各電極の前記第1の入力と前記第1の接続点との間の前記第1の導体の抵抗、及び各電極の前記第2の入力と前記第2の接続点との間の前記第2の導体の抵抗は、接続された前記電極アレイの全抵抗よりも実質的に少なくとも一桁小さい、マイクロ流体デバイス。 - 各DEP電極アレイは、1つのマイクロ流体チャネルのみに関連付けられる、請求項1に記載のマイクロ流体デバイス。
- 前記DEP電極アレイは、電気的に並列に接続されている、請求項1又は2に記載のマイクロ流体デバイス。
- 前記第1の接続点及び前記第2の接続点は、前記デバイス上の唯一の接続点である、請求項1乃至3の何れかに記載のマイクロ流体デバイス。
- 前記DEP電極アレイは、それぞれ、くし型電極(IDE)アレイを含む、請求項1乃至4の何れかに記載のマイクロ流体デバイス。
- 各IDEアレイは、5〜40個の電極を含む第2の電極セットと相互嵌合された5〜40個の電極を含む第1の電極セットを含む、請求項5に記載のマイクロ流体デバイス。
- 各IDEアレイは約2mm〜8mmの長さである、請求項5又は6に記載のマイクロ流体デバイス。
- 各IDEアレイは、約80kV/m RMSの平均電界を生成するように動作可能である、請求項7に記載のマイクロ流体デバイス。
- 前記DEP電極アレイは、それぞれ、1.6〜2.4kΩの抵抗を有する、請求項1乃至8の何れかに記載のマイクロ流体デバイス。
- 前記デバイスは、対応する分析デバイスに挿入可能なマイクロ流体カセットである、請求項1乃至9の何れかに記載のマイクロ流体デバイス。
- 少なくとも2つのDEP電極アレイを含む、請求項1乃至10の何れかに記載のマイクロ流体デバイス。
- 前記第1及び第2の導体は、導電性リードを含む、請求項1乃至11の何れかに記載のマイクロ流体デバイス。
- 前記導電性リードは、基板上に堆積された導電性材料を含む、請求項12に記載のマイクロ流体デバイス。
- 前記導電性リードの各々は、前記導電性リードのエッジ長を増加させるために、導電性材料が存在しない1つ以上の内部ギャップを含む、請求項13に記載のマイクロ流体デバイス。
- 前記導電性材料は、金、ニッケル、白金、又はアルミニウムを含む、請求項13又は14に記載のマイクロ流体デバイス。
- 前記標的粒子は標的細胞である、請求項1乃至15の何れかに記載のマイクロ流体デバイス。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1814833.8A GB2577074B (en) | 2018-09-12 | 2018-09-12 | Microfluidic device with DEP arrays |
GB1814833.8 | 2018-09-12 | ||
PCT/EP2019/074325 WO2020053328A1 (en) | 2018-09-12 | 2019-09-12 | Microfluidic device with dep arrays |
Publications (2)
Publication Number | Publication Date |
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JP2022500231A true JP2022500231A (ja) | 2022-01-04 |
JP7383697B2 JP7383697B2 (ja) | 2023-11-20 |
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Application Number | Title | Priority Date | Filing Date |
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JP2021512867A Active JP7383697B2 (ja) | 2018-09-12 | 2019-09-12 | Depアレイを有するマイクロ流体デバイス |
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Country | Link |
---|---|
US (1) | US20220040696A1 (ja) |
EP (1) | EP3849704A1 (ja) |
JP (1) | JP7383697B2 (ja) |
CN (1) | CN112703057B (ja) |
GB (1) | GB2577074B (ja) |
WO (1) | WO2020053328A1 (ja) |
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US20230191400A1 (en) * | 2021-12-17 | 2023-06-22 | Hidaca Ltd. | Well array device, system and methods of use thereof |
CN116351352A (zh) * | 2021-12-28 | 2023-06-30 | 彩科(苏州)生物科技有限公司 | 具有对称漏电流的晶体管光镊及包括该光镊的微流体设备 |
Citations (5)
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JP2011083665A (ja) * | 2009-10-13 | 2011-04-28 | Foundation For The Promotion Of Industrial Science | ダイナミックマイクロアレイ装置 |
JP2012034641A (ja) * | 2010-08-09 | 2012-02-23 | Univ Of Tokyo | 電気的機能を持つマイクロチャンバーアレイ装置およびそれを用いた検査対象物解析方法 |
JP2018057372A (ja) * | 2016-09-30 | 2018-04-12 | 国立大学法人 東京大学 | 粒子捕捉用マイクロデバイス、及びそれを用いた粒子の捕捉、濃縮、又は分離方法 |
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US10024819B2 (en) * | 2010-10-21 | 2018-07-17 | The Regents Of The University Of California | Microfluidics with wirelessly powered electronic circuits |
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JP2011083665A (ja) * | 2009-10-13 | 2011-04-28 | Foundation For The Promotion Of Industrial Science | ダイナミックマイクロアレイ装置 |
JP2012034641A (ja) * | 2010-08-09 | 2012-02-23 | Univ Of Tokyo | 電気的機能を持つマイクロチャンバーアレイ装置およびそれを用いた検査対象物解析方法 |
US20180117592A1 (en) * | 2015-04-14 | 2018-05-03 | Soojung Claire Hur | Electrode array for vortex-assisted electroporation |
JP2018057372A (ja) * | 2016-09-30 | 2018-04-12 | 国立大学法人 東京大学 | 粒子捕捉用マイクロデバイス、及びそれを用いた粒子の捕捉、濃縮、又は分離方法 |
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CN112703057B (zh) | 2023-06-06 |
WO2020053328A1 (en) | 2020-03-19 |
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