JP2022500081A5 - - Google Patents

Info

Publication number
JP2022500081A5
JP2022500081A5 JP2021538178A JP2021538178A JP2022500081A5 JP 2022500081 A5 JP2022500081 A5 JP 2022500081A5 JP 2021538178 A JP2021538178 A JP 2021538178A JP 2021538178 A JP2021538178 A JP 2021538178A JP 2022500081 A5 JP2022500081 A5 JP 2022500081A5
Authority
JP
Japan
Prior art keywords
seq
variable region
chain variable
amino acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021538178A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022500081A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/050575 external-priority patent/WO2020055975A1/en
Publication of JP2022500081A publication Critical patent/JP2022500081A/ja
Publication of JP2022500081A5 publication Critical patent/JP2022500081A5/ja
Pending legal-status Critical Current

Links

JP2021538178A 2018-09-11 2019-09-11 抗trem−2アゴニスト抗体 Pending JP2022500081A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862729458P 2018-09-11 2018-09-11
US62/729,458 2018-09-11
PCT/US2019/050575 WO2020055975A1 (en) 2018-09-11 2019-09-11 Anti-trem-2 agonist antibodies

Publications (2)

Publication Number Publication Date
JP2022500081A JP2022500081A (ja) 2022-01-04
JP2022500081A5 true JP2022500081A5 (https=) 2022-09-20

Family

ID=69777153

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021538178A Pending JP2022500081A (ja) 2018-09-11 2019-09-11 抗trem−2アゴニスト抗体

Country Status (13)

Country Link
US (1) US12145988B2 (https=)
EP (1) EP3849598A4 (https=)
JP (1) JP2022500081A (https=)
KR (1) KR20210057113A (https=)
CN (1) CN113164572A (https=)
AU (1) AU2019339452A1 (https=)
BR (1) BR112021004316A2 (https=)
CA (1) CA3111569A1 (https=)
IL (1) IL281201A (https=)
MX (1) MX2021002616A (https=)
SG (1) SG11202102162RA (https=)
WO (1) WO2020055975A1 (https=)
ZA (1) ZA202101537B (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20190248A1 (ar) 2017-04-21 2019-10-20 Amgen Inc بروتينات ربط مولد ضد trem2 واستخداماته
CN111201030B (zh) 2017-07-25 2024-11-01 真和制药有限公司 通过阻断tim-3和其配体的相互作用治疗癌症
CA3111569A1 (en) 2018-09-11 2020-03-19 Washington University Anti-trem-2 agonist antibodies
WO2020160156A2 (en) 2019-01-30 2020-08-06 Immutics, Inc. Anti-gal3 antibodies and uses thereof
BR112021015656A2 (pt) 2019-02-20 2021-10-05 Denali Therapeutics Inc. Anticorpos anti-trem2 e métodos de uso dos mesmos
JP2023512450A (ja) 2020-01-13 2023-03-27 デナリ セラピューティクス インコーポレイテッド 抗trem2抗体及びその使用方法
EP4157338A4 (en) 2020-05-26 2024-11-13 TrueBinding, Inc. METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING
WO2023192282A1 (en) * 2022-03-28 2023-10-05 Denali Therapeutics Inc. Methods for treating brain glucose hypometabolism
CA3254085A1 (en) * 2022-05-18 2023-11-23 The Brigham And Women's Hospital, Inc. KLRB1 LIAISON AGENTS AND THEIR METHODS OF USE
WO2024040194A1 (en) 2022-08-17 2024-02-22 Capstan Therapeutics, Inc. Conditioning for in vivo immune cell engineering
JP2025529287A (ja) 2022-09-06 2025-09-04 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル マルファン症候群の処置のためのtrem-2アゴニスト
WO2024160736A1 (en) * 2023-01-30 2024-08-08 Isar Bioscience Gmbh Human anti-trem2 antibody for treating neurodegenerative disorders
AU2024279278A1 (en) 2023-05-31 2025-12-18 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
US20250127728A1 (en) 2023-10-05 2025-04-24 Capstan Therapeutics, Inc. Constrained Ionizable Cationic Lipids and Lipid Nanoparticles
WO2025076113A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Ionizable cationic lipids with conserved spacing and lipid nanoparticles
US20250302763A1 (en) 2024-02-22 2025-10-02 Capstan Therapeutics, Inc. Immune engineering amplification
WO2025217452A1 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
WO2025217454A2 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Ionizable cationic lipids and lipid nanoparticles

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4741900A (en) 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
US20150140672A1 (en) 2011-12-19 2015-05-21 Washington University Methods for detecting amyloid beta amyloidosis
AU2012359020B2 (en) 2011-12-19 2017-04-13 The Washington University Methods for diagnosing Alzheimer's disease
EP2923209A4 (en) 2012-11-20 2016-04-27 Univ Washington METHOD FOR THE DIAGNOSIS OF DISEASES BY ANALYSIS OF AMYLOID BETA ENRICHMENT KINETICS
WO2015116753A1 (en) * 2014-01-29 2015-08-06 Dana-Farber Cancer Institute, Inc. Antibodies against the muc1-c/extracellular domain (muc1-c/ecd)
CA2955086A1 (en) 2014-08-08 2016-02-11 Alector Llc Anti-trem2 antibodies and methods of use thereof
WO2016064895A1 (en) * 2014-10-20 2016-04-28 The Brigham And Women's Hospital, Inc. Targeting apolipoprotein e (apoe) in neurologic disease
WO2017058866A1 (en) * 2015-09-28 2017-04-06 Precision Immune, Inc. Anti-trem2 antibodies and uses thereof
US20190330335A1 (en) * 2015-10-06 2019-10-31 Alector Llc Anti-trem2 antibodies and methods of use thereof
CN109641961A (zh) * 2016-07-22 2019-04-16 德国神经退行性疾病研究中心 Trem2切割调节剂及其用途
CA3111569A1 (en) 2018-09-11 2020-03-19 Washington University Anti-trem-2 agonist antibodies

Similar Documents

Publication Publication Date Title
JP2022500081A5 (https=)
JP2020506162A5 (https=)
US12503501B2 (en) Treatment of central nervous system disorders by intranasal administration of immunoglobulin G
AU2024216537A1 (en) Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
ES2902467T3 (es) TIMP2 para su uso en el tratamiento de afecciones asociadas al envejecimiento
Afridi et al. New onset migraine with a brain stem cavernous angioma
Prasetyo The primary, secondary, and tertiary brain injury
Shivakumar et al. Do schizophrenia patients age early?
US20190328782A1 (en) Dosing Regimen for Treatment of Cognitive and Motor Impairments with Blood Plasma and Blood Plasma Products
JP2020506162A (ja) 抗apoe抗体
US12084491B2 (en) Treatment of Parkinson's disease
WO2020018343A1 (en) Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
Kase et al. Shotgun pellet embolus to the middle cerebral artery
García-Cazorla et al. White matter alterations associated with chromosomal disorders
JPWO2002076492A1 (ja) 新規な運動障害改善剤
RU2021109803A (ru) Антитела-агонисты trem-2
AU2021331859A1 (en) Peptide composition for prevention or treatment of Alzheimer's disease
Watanabe et al. Steroid-responsive limbic encephalitis
Keith et al. Neuropathological homology in true Galloway-Mowat syndrome
US20250127734A1 (en) Alz-801 for use in treating a covid-19 associated neurological symptom
Croisile Benson’s syndrome or posterior cortical atrophy
JP7299304B2 (ja) 脳損傷を回復させるための上皮成長因子と分泌促進物質ペプチドghrp6とを含む薬学的組合せ
US20190038613A1 (en) Combination therapy
Kanuri et al. Posterior Reversible Encephalopathy Syndrome (PRES): Deceptive Facade than Meets the Eye
Sabau et al. Hypoparathyroidism diagnosed by neurological signs and widespread intracerebral calcifications