JP2022111148A5 - - Google Patents
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- Publication number
- JP2022111148A5 JP2022111148A5 JP2022084854A JP2022084854A JP2022111148A5 JP 2022111148 A5 JP2022111148 A5 JP 2022111148A5 JP 2022084854 A JP2022084854 A JP 2022084854A JP 2022084854 A JP2022084854 A JP 2022084854A JP 2022111148 A5 JP2022111148 A5 JP 2022111148A5
- Authority
- JP
- Japan
- Prior art keywords
- icos
- bispecific antibody
- monomer
- antibody
- light chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662381239P | 2016-08-30 | 2016-08-30 | |
| US62/381,239 | 2016-08-30 | ||
| US201762456033P | 2017-02-07 | 2017-02-07 | |
| US62/456,033 | 2017-02-07 | ||
| US201762479723P | 2017-03-31 | 2017-03-31 | |
| US62/479,723 | 2017-03-31 | ||
| US15/623,314 US10787518B2 (en) | 2016-06-14 | 2017-06-14 | Bispecific checkpoint inhibitor antibodies |
| US15/623,314 | 2017-06-14 | ||
| JP2019511464A JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
| PCT/US2017/049497 WO2018045110A1 (en) | 2016-08-30 | 2017-08-30 | Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511464A Division JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022111148A JP2022111148A (ja) | 2022-07-29 |
| JP2022111148A5 true JP2022111148A5 (cg-RX-API-DMAC7.html) | 2023-02-20 |
Family
ID=65632988
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511464A Active JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
| JP2022084854A Pending JP2022111148A (ja) | 2016-08-30 | 2022-05-24 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511464A Active JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP3507306B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP7080219B2 (cg-RX-API-DMAC7.html) |
| KR (2) | KR102575681B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN110267990B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2017321625A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3035343A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK3507306T3 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20251424T1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL265046B2 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2023006786A (cg-RX-API-DMAC7.html) |
| SG (1) | SG11201901712YA (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201901752B (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3044323B1 (en) * | 2013-09-13 | 2022-04-06 | F. Hoffmann-La Roche AG | Methods for detecting and quantifying host cell protein in cell lines |
| KR102170077B1 (ko) * | 2018-05-21 | 2020-10-27 | 인하대학교 산학협력단 | Prss14/st14의 자가분해 고리부분을 특이적으로 인식하는 단일클론항체 및 이의 용도 |
| CN112996813A (zh) * | 2018-10-31 | 2021-06-18 | 生物蛋白有限公司 | 抗ctla4抗体、抗体片段、其免疫结合物和其用途 |
| AU2021257570A1 (en) * | 2020-04-14 | 2022-11-03 | Glaxosmithkline Intellectual Property Development Limited | Combination treatment for cancer |
| JP2023521228A (ja) * | 2020-04-14 | 2023-05-23 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド | 癌の併用療法 |
| CN116615442A (zh) * | 2020-09-08 | 2023-08-18 | 优特力克斯有限公司 | 程序性细胞死亡1多肽变体 |
| CN114195900B (zh) * | 2020-09-17 | 2024-02-23 | 普米斯生物技术(珠海)有限公司 | 一种抗4-1bb/pd-l1双特异性抗体及其用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8546543B2 (en) * | 2004-11-12 | 2013-10-01 | Xencor, Inc. | Fc variants that extend antibody half-life |
| TWI605828B (zh) * | 2008-12-09 | 2017-11-21 | 建南德克公司 | 抗ｐｄ-ｌ１抗體及其於增進ｔ細胞功能之用途 |
| WO2012065055A2 (en) * | 2010-11-12 | 2012-05-18 | The Rockefeller University | Fusion proteins for hiv therapy |
| UY34887A (es) * | 2012-07-02 | 2013-12-31 | Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware | Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos |
| CA3211863A1 (en) * | 2013-01-14 | 2014-07-17 | Xencor, Inc. | Novel heterodimeric proteins |
| EP2951203B1 (en) * | 2013-03-15 | 2019-05-22 | Xencor, Inc. | Heterodimeric proteins |
| US10544187B2 (en) * | 2013-03-15 | 2020-01-28 | Xencor, Inc. | Targeting regulatory T cells with heterodimeric proteins |
| EP3024851B1 (en) * | 2013-07-25 | 2018-05-09 | CytomX Therapeutics, Inc. | Multispecific antibodies, multispecific activatable antibodies and methods of using the same |
| NZ720353A (en) * | 2013-12-30 | 2019-12-20 | Epimab Biotherapeutics Inc | Fabs-in-tandem immunoglobulin and uses thereof |
| EA201790834A1 (ru) * | 2014-10-14 | 2018-01-31 | Новартис Аг | Молекулы антител к pd-l1 и их применение |
| EA038349B1 (ru) * | 2014-11-21 | 2021-08-12 | Бристол-Маерс Сквибб Компани | Антитела, содержащие модифицированные константные участки тяжелой цепи |
| SG11201704274QA (en) * | 2014-11-26 | 2017-06-29 | Xencor Inc | Heterodimeric antibodies that bind cd3 and cd38 |
| PT3242890T (pt) * | 2015-01-08 | 2019-12-10 | Genmab As | Agentes de ligação agonistas do recetor de tnf |
| EP3245227A4 (en) * | 2015-01-14 | 2018-07-25 | Compass Therapeutics LLC | Multispecific immunomodulatory antigen-binding constructs |
| MA41414A (fr) * | 2015-01-28 | 2017-12-05 | Centre Nat Rech Scient | Protéines de liaison agonistes d' icos |
-
2017
- 2017-08-30 CN CN201780060900.7A patent/CN110267990B/zh active Active
- 2017-08-30 IL IL265046A patent/IL265046B2/en unknown
- 2017-08-30 AU AU2017321625A patent/AU2017321625A1/en not_active Abandoned
- 2017-08-30 HR HRP20251424TT patent/HRP20251424T1/hr unknown
- 2017-08-30 KR KR1020197009280A patent/KR102575681B1/ko active Active
- 2017-08-30 SG SG11201901712YA patent/SG11201901712YA/en unknown
- 2017-08-30 JP JP2019511464A patent/JP7080219B2/ja active Active
- 2017-08-30 KR KR1020237029969A patent/KR20230130174A/ko not_active Ceased
- 2017-08-30 CA CA3035343A patent/CA3035343A1/en active Pending
- 2017-08-30 EP EP17765002.5A patent/EP3507306B1/en active Active
- 2017-08-30 DK DK17765002.5T patent/DK3507306T3/da active
-
2019
- 2019-02-27 MX MX2023006786A patent/MX2023006786A/es unknown
- 2019-03-20 ZA ZA2019/01752A patent/ZA201901752B/en unknown
-
2022
- 2022-05-24 JP JP2022084854A patent/JP2022111148A/ja active Pending