JP2022111148A5 - - Google Patents
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- Publication number
- JP2022111148A5 JP2022111148A5 JP2022084854A JP2022084854A JP2022111148A5 JP 2022111148 A5 JP2022111148 A5 JP 2022111148A5 JP 2022084854 A JP2022084854 A JP 2022084854A JP 2022084854 A JP2022084854 A JP 2022084854A JP 2022111148 A5 JP2022111148 A5 JP 2022111148A5
- Authority
- JP
- Japan
- Prior art keywords
- icos
- bispecific antibody
- monomer
- antibody
- light chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662381239P | 2016-08-30 | 2016-08-30 | |
| US62/381,239 | 2016-08-30 | ||
| US201762456033P | 2017-02-07 | 2017-02-07 | |
| US62/456,033 | 2017-02-07 | ||
| US201762479723P | 2017-03-31 | 2017-03-31 | |
| US62/479,723 | 2017-03-31 | ||
| US15/623,314 | 2017-06-14 | ||
| US15/623,314 US10787518B2 (en) | 2016-06-14 | 2017-06-14 | Bispecific checkpoint inhibitor antibodies |
| JP2019511464A JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
| PCT/US2017/049497 WO2018045110A1 (en) | 2016-08-30 | 2017-08-30 | Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511464A Division JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022111148A JP2022111148A (ja) | 2022-07-29 |
| JP2022111148A5 true JP2022111148A5 (cg-RX-API-DMAC10.html) | 2023-02-20 |
Family
ID=65632988
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511464A Active JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
| JP2022084854A Pending JP2022111148A (ja) | 2016-08-30 | 2022-05-24 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511464A Active JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
Country Status (12)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3044323T3 (pl) * | 2013-09-13 | 2022-06-27 | F.Hoffmann-La Roche Ag | Sposoby wykrywania i ilościowego oznaczania białka komórki gospodarza w liniach komórkowych |
| KR102170077B1 (ko) * | 2018-05-21 | 2020-10-27 | 인하대학교 산학협력단 | Prss14/st14의 자가분해 고리부분을 특이적으로 인식하는 단일클론항체 및 이의 용도 |
| MX2021005048A (es) * | 2018-10-31 | 2021-09-08 | Bioatla Inc | Anticuerpos anti-ctla4, fragmentos de anticuerpos, sus inmunoconjugados y usos. |
| JP2023521228A (ja) * | 2020-04-14 | 2023-05-23 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド | 癌の併用療法 |
| WO2021209356A1 (en) * | 2020-04-14 | 2021-10-21 | Glaxosmithkline Intellectual Property Development Limited | Combination treatment for cancer |
| WO2022053864A1 (en) * | 2020-09-08 | 2022-03-17 | Kwon Byoung S | Pd-1 polypeptide variants |
| CN114195900B (zh) * | 2020-09-17 | 2024-02-23 | 普米斯生物技术(珠海)有限公司 | 一种抗4-1bb/pd-l1双特异性抗体及其用途 |
| KR102911451B1 (ko) * | 2022-05-24 | 2026-01-09 | 건국대학교 글로컬산학협력단 | Rps3 결합 단클론 항체 및 이의 용도 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8546543B2 (en) * | 2004-11-12 | 2013-10-01 | Xencor, Inc. | Fc variants that extend antibody half-life |
| MX356367B (es) * | 2008-12-09 | 2018-05-25 | Genentech Inc | Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t. |
| CN103282385A (zh) * | 2010-11-12 | 2013-09-04 | 美国洛克菲勒大学 | 用于hiv治疗的融合蛋白 |
| AR091649A1 (es) * | 2012-07-02 | 2015-02-18 | Bristol Myers Squibb Co | Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos |
| KR102391731B1 (ko) * | 2013-01-14 | 2022-04-27 | 젠코어 인코포레이티드 | 신규한 이형이량체 단백질 |
| EP3587448B1 (en) * | 2013-03-15 | 2021-05-19 | Xencor, Inc. | Heterodimeric proteins |
| EP3421495A3 (en) * | 2013-03-15 | 2019-05-15 | Xencor, Inc. | Modulation of t cells with bispecific antibodies and fc fusions |
| JP6693872B2 (ja) * | 2013-07-25 | 2020-05-13 | シトムクス セラピューティクス,インコーポレイティド | 多重特異性抗体、多重特異性活性化可能抗体、及びそれらの使用方法 |
| AU2014374055B2 (en) | 2013-12-30 | 2018-11-08 | Epimab Biotherapeutics Inc. | Fabs-in-tandem immunoglobulin and uses thereof |
| SG11201702401RA (en) * | 2014-10-14 | 2017-04-27 | Novartis Ag | Antibody molecules to pd-l1 and uses thereof |
| ES2826566T3 (es) * | 2014-11-21 | 2021-05-18 | Bristol Myers Squibb Co | Anticuerpos que comprenden regiones constantes pesadas modificadas |
| HK1245171A1 (zh) * | 2014-11-26 | 2018-08-24 | Xencor, Inc. | 结合cd3和cd38的异二聚体抗体 |
| SMT201900702T1 (it) * | 2015-01-08 | 2020-01-14 | Genmab As | Agenti agonistici leganti il recettore del tnf |
| WO2016115274A1 (en) * | 2015-01-14 | 2016-07-21 | Compass Therapeutics Llc | Multispecific immunomodulatory antigen-binding constructs |
| MA41414A (fr) * | 2015-01-28 | 2017-12-05 | Centre Nat Rech Scient | Protéines de liaison agonistes d' icos |
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2017
- 2017-08-30 HR HRP20251424TT patent/HRP20251424T1/hr unknown
- 2017-08-30 DK DK17765002.5T patent/DK3507306T3/da active
- 2017-08-30 IL IL265046A patent/IL265046B2/en unknown
- 2017-08-30 KR KR1020237029969A patent/KR20230130174A/ko not_active Ceased
- 2017-08-30 SG SG11201901712YA patent/SG11201901712YA/en unknown
- 2017-08-30 JP JP2019511464A patent/JP7080219B2/ja active Active
- 2017-08-30 CN CN201780060900.7A patent/CN110267990B/zh active Active
- 2017-08-30 EP EP17765002.5A patent/EP3507306B1/en active Active
- 2017-08-30 AU AU2017321625A patent/AU2017321625A1/en not_active Abandoned
- 2017-08-30 CA CA3035343A patent/CA3035343A1/en active Pending
- 2017-08-30 KR KR1020197009280A patent/KR102575681B1/ko active Active
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2019
- 2019-02-27 MX MX2023006786A patent/MX2023006786A/es unknown
- 2019-03-20 ZA ZA2019/01752A patent/ZA201901752B/en unknown
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2022
- 2022-05-24 JP JP2022084854A patent/JP2022111148A/ja active Pending