JP2022103138A - Oil-in-water type emulsion cosmetic - Google Patents

Abstract

To provide an oil-in-water type emulsion cosmetic which is reduced in stimulation feeling while containing nicotinic acid amide at a high concentration, does not give sticky feeling even when the total amount of oil components is 15 mass% or more and has comprehensively good sense of use.SOLUTION: There are provided: an oil-in-water type emulsion cosmetic comprising nicotinic acid amide, a water-holding oil agent, an acrylamide-based polymer, a polyhydric alcohol fatty acid ester and water; a method for producing the oil-in-water type emulsion cosmetic; or the like.SELECTED DRAWING: None

Description

The present invention relates to an oil-in-water emulsified cosmetic.

The oil-in-water emulsified cosmetic has an aqueous phase as a continuous phase, and while having a moist feeling, the oil content contains a water-retaining action that retains an appropriate amount of water on the skin and the water inside the living body. It has a moisturizing effect such as a water barrier effect that prevents it from being lost.

Further, by adding a functional ingredient to the oil-in-water emulsified cosmetic, it is possible to impart a physiologically active effect as well as a moisturizing effect. One such functional ingredient is nicotinamide. Nicotinamide is a kind of vitamins and has been widely used in the skin care field as a functional component showing blood circulation promoting activity, anti-inflammatory activity, ceramide synthesis promoting activity and the like.

In recent years, in order to effectively exert various bioactive effects of nicotinamide, attempts have been made to design a formulation in which nicotinamide is blended at a high concentration. However, those containing a high concentration of nicotinamide cause skin irritation and become sticky, which causes a problem that the feeling of use is deteriorated.

To solve such a problem, Patent Document 1 contains nicotinic acid amide, sodium stearoylmethyltaurine, a sterol derivative and water, and the mass ratio of nicotinic acid amide to sodium stearoylmethyltaurine is constant. The relevant oil-in-water emulsified compositions are described.

Further, as those containing nicotinamide at a relatively high concentration, an aqueous beauty solution containing water-soluble polysaccharides such as nicotinamide and white jellyfish polysaccharide (Patent Document 2), nicotinamide, katasumuri secretion, mica and There is a skin cream containing hydrogenated phosphatidylcholine (Patent Document 3).

Patent No. 6495685 Japanese Unexamined Patent Publication No. 2019-131547 Chinese Patent Application Publication No. 107233282

The oil-in-water emulsified composition described in Patent Document 1 attempts to suppress the irritation of nicotinamide with a sterol derivative, and further suppresses the stickiness of nicotinamide and the sterol derivative with sodium stearoylmethyltaurine. ..

However, stearoylmethyltaurine sodium is irritating in itself. In fact, according to the investigation by the present inventors, the oil-in-water emulsified cosmetic containing nicotinamide and stearoylmethyltaurine sodium has a stimulating feeling as compared with the oil-in-water emulsified cosmetic containing only nicotinamide. I felt.

In addition, when the oil content is low, the stickiness of nicotinamide and the sterol derivative may be suppressed by sodium stearoylmethyltaurine. However, according to the investigation by the present inventors, when the total amount of oil is 15% by mass or more, a large amount of sodium stearoylmethyltaurine must be blended, and the resulting oil-in-water emulsified makeup must be blended. The fee became more stimulating.

On the other hand, the aqueous beauty essence described in Patent Document 2 and the skin cream described in Patent Document 3 each contain a water-soluble polysaccharide such as a thickened white jellyfish polysaccharide and a katatsumuri secretion liquid to obtain a desired viscosity. It is difficult to adjust so that it becomes.

Further, according to the investigation by the present inventors, the aqueous beauty liquid described in Patent Document 2 is based on the content of a water-holding oil which is a macadamia nut oil fatty acid phytosteryl and a (Na acrylate / Na acryloyldimethyltaurine) copolymer. The content of a certain acrylamide-based polymer is low, and as a result, the aqueous beauty liquid described in Patent Document 2 has a problem of inferior stability over time.

Further, since the skin cream described in Patent Document 3 contains a powdery inorganic pigment such as mica, it must contain a large amount of a surface-active emulsifier such as hydrogenated phosphatidylcholine for dispersing the inorganic pigment. However, as a result, there is a problem that the amount of oil contained is limited.

Therefore, the present invention does not feel sticky even when the total amount of oil is 15% by mass or more, and the irritating feeling is reduced even though the nicotinamide is contained in a high concentration, and the overall feeling of use is achieved. It is an object to be solved by the invention to provide an oil-in-water emulsified cosmetic having a good quality and stability.

In order to solve the above problems, the present inventors attempted to design a formulation of an oil-in-water emulsified cosmetic containing nicotinic acid amide and a sterol derivative without using an irritating surfactant such as stearoylmethyltaurine sodium. rice field. However, even if nicotinamide, which is a water-soluble component, and a sterol derivative, which is an oily component, are mixed and emulsified, it is difficult to ensure stability over time, and this should be done without using a surfactant. It was extremely difficult.

Nevertheless, the present inventors have studied various cosmetic ingredients, which are said to have hundreds of types even if they are used as emulsifiers, and while containing a high concentration of nicotinic acid amide, they have a stimulating feeling and a feeling of irritation. Repeated trial and error was repeated to obtain an oil-in-water emulsified cosmetic with reduced stickiness and good usability.

As a result of diligent research and development by the present inventors, finally, while containing a high concentration of nicotinic acid amide, a phytosterol derivative among sterol derivatives, an acrylamide polymer and a polyhydric alcohol fatty acid ester were blended, and further. By setting the content of the phytosterol derivative and the acrylamide polymer in a predetermined range, it is possible to obtain an oil-in-water emulsified cosmetic that does not cause irritation, has reduced stickiness, and has a good usability. succeeded in.

Moreover, surprisingly, the above-mentioned oil-in-water emulsified cosmetic can set the total amount of oil to 15% by mass or more, yet can maintain its properties under both low-temperature storage conditions and high-temperature storage conditions. It turned out to be highly stable. That is, it has been found that the oil-in-water emulsified cosmetic can exhibit an excellent moisturizing effect depending on the oil content contained therein.

On the other hand, the present inventors considered that the suppressive effect of nicotinamide on the phytosterol derivative may be due to the water holding property of the phytosterol derivative. Therefore, it was found that when a water-holding oil having a structure different from that of the phytosterol derivative was used, the irritation caused by nicotinamide was suppressed in the same manner as the phytosterol derivative.

Based on these findings, the present inventors have prepared nicotinic acid amides, water-holding oils, acrylamide-based polymers, polyhydric alcohol fatty acid esters, and water to solve the problems of the present invention. We will create an oil-in-water emulsified cosmetic that contains 15% by mass or more of oil and is excellent in usability and stability, but can be expected to have a physiologically active effect by nicotinic acid amide and a moisturizing effect by oil. I succeeded in doing so. The present invention is an invention completed based on these findings and successful examples.

Therefore, as one aspect of the present invention, the oil-in-water emulsified cosmetics and methods according to each of the following aspects are provided.
[1] An oil-in-water emulsified cosmetic containing nicotinic acid amide, a water-holding oil, an acrylamide polymer, a polyhydric alcohol fatty acid ester, and water.
The content of the nicotinamide is 3% by mass to 8% by mass.
The content of the water-holding oil is 1.5% by mass to 15% by mass, and the content is 1.5% by mass to 15% by mass.
The content of the acrylamide-based polymer is 0.5% by mass to 8% by mass in the case of the acrylamide-based polymer of the copolymer, and 0.4% by mass or more in the case of the acrylamide-based polymer of the homopolymer. It is 8% by weight and the total oil content is 15% to 40% by weight.
The oil-in-water emulsified cosmetic.
[2] The oil-in-water emulsified cosmetic according to [1], wherein the oil-in-water emulsified cosmetic has an inorganic pigment content of less than 1% by mass.
[3] The oil-in-water emulsified cosmetic has a total content of a stimulating surfactant selected from the group consisting of sodium stearoylmethyltaurine and polysorbate 80 in an amount of 0% by mass to 0.5% by mass [1]. The oil-in-water emulsified cosmetic according to any one of [2].
[4] The water according to any one of [1] to [3], wherein the water-holding oil is at least one water-holding oil selected from the group consisting of a phytosterol derivative and a polyhydric alcohol hydroxy fatty acid ester. Oil-type emulsified cosmetics.
[5] The phytosterol derivative is dilauroyl glutamate (phytosteryl / octyldodecyl), dilauroyl glutamate (octyldodecyl / phytosteryl / behenyl), macadamia nut fatty acid phytosteryl, dimer dilinoleic acid (phytosteryl / isostearyl / cetyl / stearyl / behenyl). , At least one phytosterol derivative selected from the group consisting of phytosteryl isostearate and phytosteryl hydroxystearate, and / or said polyhydric alcohol hydroxy fatty acid ester is dipentaerythrityl tripolyhydroxystearate and hexa (hydroxystearic acid / stearic acid). / Logonic acid) The oil-in-water emulsified cosmetic according to [4], which is at least one polyhydric alcohol hydroxy fatty acid ester selected from the group consisting of dipentaerythrityl.
[6] The acrylamide-based polymer is at least one acrylamide-based polymer selected from the group consisting of (sodium acrylate / sodium acryloyldimethyltaurine) copolymer, (hydroxyethyl acrylate / sodium acryloyldimethyltaurine) copolymer and polyacrylamide. The oil-in-water emulsified cosmetic according to any one of [1] to [5], which is a molecule.
[7] The polyhydric alcohol fatty acid ester includes triethylhexanoin, pentaerythrityl tetraethylhexanoic acid, tri (caprylic acid / capric acid) glyceryl, tri (caprylic acid / capric acid / myristic acid / stearic acid) glyceryl, and dicapric acid. The oil-in-water emulsified cosmetic according to any one of [1] to [6], which is at least one polyhydric alcohol ester selected from the group consisting of neopentyl glycol and neopentyl glycol diethylhexanoic acid.
[8] The content of the polyhydric alcohol fatty acid ester is 1% by mass to 14% by mass, and / or the content of the water is 40% by mass to 75% by mass, according to [1] to [7]. The oil-in-water emulsified cosmetic according to any one of the following items.
[9] Oil-in-water emulsified makeup by sequentially adding an acrylamide-based polymer and an oil phase containing a water-holding oil agent and a polyhydric alcohol fatty acid ester to an aqueous phase containing nicotinic acid amide and water and emulsifying them. A method for producing an oil-in-water emulsified cosmetic, which comprises a step of obtaining an ester.

According to the present invention, although the nicotinamide is contained in a high concentration, the irritation feeling is reduced, and even when the oil content is 15% by mass or more, no stickiness is felt, and comprehensively. It is possible to provide an oil-in-water emulsified cosmetic having a good usability. That is, the oil-in-water emulsified cosmetic according to one aspect of the present invention is expected to exhibit the physiologically active action and the moisturizing action of the oil content by the contained nicotinamide, and the irritation feeling is reduced and the stickiness is not felt. Therefore, it is expected to be used on a daily basis with a good feeling of use.

Further, since the oil-in-water emulsified cosmetic according to one aspect of the present invention has excellent stability, it can be used and stored for a long period of time. Further, according to the method of one aspect of the present invention, it is possible to produce the oil-in-water emulsified cosmetic of one aspect of the present invention easily and on an industrial scale.

Hereinafter, the details of the oil-in-water emulsified cosmetic and the method, which is one aspect of the present invention, will be described, but the present invention may take various aspects as long as the object is achieved.

Unless otherwise specified, the terms used herein are used in the sense commonly used by those skilled in the art of cosmetics and should not be construed as having an unreasonably limited meaning. In addition, since the theories and guesses made in the present specification are based on the knowledge and experience of the present inventors, the technical scope of the present invention is limited only by such theories and guesses. It is not something that will be done.

Of the terms used herein,
“And / or” means any one, or any combination of two or more, or all combinations of the plurality of related items listed.
"Content" is synonymous with concentration and means the ratio of the amount of the ingredient to the total amount of the oil-in-water emulsified cosmetic. However, the total content of each component does not exceed 100%. In the present specification, unless otherwise specified, the unit of content means "mass% (wt%)". When a commercially available product is used, the content of the component is preferably the amount of the component contained in the commercially available product, but may be the amount of the commercially available product itself.
In the present specification, "-" in the numerical range is a range including the numerical values before and after it. For example, "0% by mass to 100% by mass" is 0% by mass or more and 100% by mass or less. It means a certain range. "Excess" and "less than" mean the lower limit and the upper limit, respectively, which do not include the previous numerical value. For example, "1 excess" means a numerical value larger than 1, and "less than 100" means a numerical value smaller than 100. do.
"Including" means that elements other than those specified as being included can be added (synonymous with "at least including"), but includes "consisting of" and "essentially consisting of". .. That is, "contains" can mean that it contains an explicit element and any one or more of the elements and consists of, or essentially consists of, the explicit elements. .. Examples of the element include restrictions such as components, processes, conditions, and parameters.
The oil-in-water emulsified cosmetic with a good "feel" is the skin on the inside of the forearm, which is a cosmetic that is filled in a standard bottle and stored at 20 ° C overnight at 20 ° C, as described in Examples described later. An oil-in-water emulsified cosmetic that has good irritation and stickiness when applied to.
An oil-in-water emulsified cosmetic having "stability" means that the entire cosmetic is uniform when the stability test as described in Examples described later is carried out, and crystals are formed when stretched on an acrylic plate. An oil-in-water emulsified cosmetic with no confirmed substances or aggregates or no rough texture.

The number of digits of an integer value matches the number of digits of significant digits. For example, 1 significant digit is 1 digit and 10 significant digit is 2 digits. In addition, the number of digits after the decimal point and the number of significant digits are the same for decimal digits. For example, 0.1 significant digit is 1 digit and 0.10 significant digit is 2 digits.

The oil-in-water emulsified cosmetic according to one aspect of the present invention comprises nicotinic acid amide (component (A)), a water-holding oil (component (B)), an acrylamide polymer (component (C)), and a multivalent value. It contains an alcohol fatty acid ester (component (D)) and water (component (E)).

The nicotinic acid amide of the component (A) is an amide compound of nicotinic acid (vitamin B ₃ , also called niacin), and is a derivative of nicotinic acid also called nicotinamide and niacinamide.

The component (A) nicotinamide is a water-soluble vitamin and is one of the B vitamins. The component (A) is used as a component contained in the aqueous phase, and functions to impart a physiologically active action such as a blood circulation promoting action, an anti-inflammatory action, and a ceramide synthesis promoting action to the oil-in-water emulsified cosmetic. The component (A) can be obtained by extracting from a natural product (rice bran or the like), synthesizing by a known method, or the like. Further, the component (A) may be commercially available.

The content of the nicotinamide of the component (A) is an amount capable of exerting the desired physiological activity of the nicotinamide when the oil-in-water emulsified cosmetic is applied to the skin, specifically, 3 mass by mass. % Or more. However, if the content of nicotinic acid amide is high, an excessive irritation feeling can be given to the oil-in-water emulsified cosmetic, so that the content of nicotinic acid amide of the component (A) is 3% by mass to 8% by mass. It is preferably 4% by mass to 7% by mass, and more preferably 4.5% by mass to 6% by mass.

The water-holding oil agent of the component (B) may be an oil agent capable of retaining water equal to or more than its own weight, that is, an oil agent having a water-holding power of 100% or more. The component (B) can contain water to form a uniform paste state. The component (B) is used as a component contained in the oil phase, mainly functions to suppress the irritation of the component (A), and further, together with the component (C) and the component (D), is used in an oil-in-water emulsified cosmetic. Can function to increase stability.

The "oil having a water holding capacity of 100% or more" is a method according to the British Pharmacopoeia (BP) "Lanolin water content measurement method". Specifically, 10 g of the oil is weighed in a 500 mL plastic container. Then, while adding pure water (“pure water” (ion-exchanged water); manufactured by Shoki Yakuhin Kogyo Co., Ltd.) little by little with a dropper, knead using a stirring rod (φ12 × 300 mm; material: POM (Duracon)) (about 0. 5 mL / min), then the test is terminated when pure water cannot be kneaded (excessive water is removed as much as possible), and the oil holding capacity calculated by the following formula is 100% or more.
Water holding capacity (%) = [Increased water weight (g)] / [Starting oil weight (10 g)] x 100

The water-holding oil agent of the component (B) is preferably a phytosterol derivative and a polyhydric alcohol hydroxy fatty acid ester from the viewpoint of satisfactorily suppressing the irritation of the component (A). From the same viewpoint, phytosterol derivatives include dilauroyl glutamate (phytosteryl / octyldodecyl), dilauroyl glutamate (octyldodecyl / phytosteryl / behenyl), macadamia nut fatty acid phytosteryl, and dimer dilinoleic acid (phytosteryl / isostearyl / cetyl /). Stearyl / behenyl), phytosteryl isostearate, phytosteryl hydroxystearate and the like are preferred; as the polyhydric alcohol hydroxy fatty acid ester, dipentaerythrityl tripolyhydroxystearate, hexa (hydroxystearic acid / stearic acid / loginic acid) dipentaerythrityl and the like are preferable. , Di (phytosteryl / octyldodecyl) lauroyl glutamate, macadamia nut fatty acid phytosteryl and dipentaerythrityl tripolyhydroxystearate are more preferable from the viewpoint of better suppressing the irritation of the component (A). The component (B) may be one of the above-mentioned ones alone or a combination of two or more kinds.

The component (B) may be extracted or synthesized by a method known so far, or may be commercially available. Commercially available products include, for example, "Eldu (registered trademark) PS-203" (manufactured by Ajinomoto Co., Inc.) as di (phytosteryl / octyldodecyl) lauroyl glutamate, and "Eldu" as di (octyldodecyl / phytosteryl / behenyl) lauroyl glutamate. (Registered trademark) PS-304 "(manufactured by Ajinomoto Co., Inc.)," PLANDOOL ^TM -MAS "(manufactured by Nippon Seika Co., Ltd.) as macadamia nut fatty acid phytosteryl, and dimer dilinolic acid (phytosteryl / isostearyl / cetyl / stearyl / behenyl). "PLANDOL ^TM -S" (manufactured by Nippon Seika Co., Ltd.), "PLANDOL ^TM -ISS" (manufactured by Nippon Seika Co., Ltd.) as phytosteryl isostearate, "Saracos FH" (manufactured by Nisshin Oillio Group) as phytosteryl hydroxystearate, "Saracos WO-6" (manufactured by Nisshin Oillio Group) as dipentaerythrityl tripolyhydroxystearate, "Cosmol 168ARV" (manufactured by Nisshin Oillio Group) as hexa (hydroxystearic acid / stearic acid / loginic acid) dipentaerythrityl, etc. However, it is not limited to these.

The content of the component (B) is an amount that can function to suppress the stimulating feeling of the component (A), and specifically, is 1.5% by mass to 15% by mass. However, the content of the component (B) is preferably 1.5% by mass to 12% by mass, preferably 2.0, in order to enhance the stability of the oil-in-water emulsified cosmetic according to one aspect of the present invention. It is more preferably from% by mass to 10% by mass, and even more preferably from 3.0% by mass to 5.0% by mass. When the content of the component (B) is within these ranges, the oil-in-water emulsified cosmetic according to one aspect of the present invention can be expected to exert a physiologically active effect while suppressing a feeling of irritation. The component (A) can be contained.

The acrylamide-based polymer of the component (C) is an organic polymer having a structure derived from the acrylamide structure (CH ₂ = CH-CO-NH-) in the molecule, and is a homopolymer having one constituent unit. It may be a copolymer having two or more kinds of constituent units. The component (C) is used when mixing the aqueous phase and the oil phase, and functions as a so-called emulsifier. The oil-in-water emulsified cosmetic according to one aspect of the present invention has an advantage that it does not have to contain a surfactant, particularly an irritating surfactant, for the purpose of emulsification by containing the component (C).

Examples of the acrylamide-based polymer of the homopolymer include polyacrylamide and the like. Examples of the acrylamide-based polymer of the copolymer include (meth) acrylic acid / (meth) acryloyl dialkyl taurine copolymer and its salt, (meth) hydroxyalkyl acrylate / (meth) acryloyl dialkyl taurine copolymer and its salt. And so on. The acrylamide polymer may be one of these alone or a combination of two or more. In addition, (meth) acrylic acid is a general term for acrylic acid and methacrylic acid.

The component (C) is polyacrylamide, (meth) from the viewpoint that the aqueous phase containing the component (A) and the oil phase containing the component (B) and the component (D) can be satisfactorily mixed and made uniform. ) Acrylic acid / (meth) acryloyl dialkyl taurine copolymer and a salt thereof, (meth) hydroxyalkyl acrylate / (meth) acryloyl dialkyl taurine copolymer and a salt thereof are preferable. Examples of the salt include sodium salt and potassium salt, but sodium salt is preferable. Preferred specific examples of the component (C) are polyacrylamide and (Na acrylate / Na acryloyldimethyltaurine) copolymer and (hydroxyethyl acrylate / Na acryloyldimethyltaurine) copolymer.

The component (C) may be extracted or synthesized by a method known so far, or may be commercially available. As commercially available products, for example, "SEPIGEL 305" (manufactured by SEPPIC) as polyacrylamide, "SIMULGEL ^TM EG" (manufactured by SEPPIC) as a copolymer (Na acrylate / acryloyldimethyltaurine Na), (acrylic acid). Examples of the hydroxyethyl acrylate / acryloyldimethyltaurine Na) copolymer include, but are not limited to, "SIMULGEL ^TM FL" (manufactured by SEPPIC).

The content of the component (C) is an amount that can mix and homogenize the aqueous phase and the oil phase when preparing an oil-in-water emulsified cosmetic, specifically, when the component (C) is a copolymer. Is 0.5% by mass to 8% by mass, and 0.4% by mass to 8% by mass when the component (C) is a homopolymer. However, the content of the component (C) is 0 when the component (C) is a copolymer in order to enhance the stability of the oil-in-water emulsified cosmetic according to one aspect of the present invention and maintain a good usability. It is preferably .75% by mass to 2.5% by mass, more preferably 0.85% by mass to 1.5% by mass; 0.6% by mass when the component (C) is a homopolymer. It is preferably from 3% by mass, more preferably from 0.8% by mass to 2% by mass. When the content of the component (C) is within these ranges, the oil-in-water emulsified cosmetic according to one aspect of the present invention is used as a result of good emulsification being achieved and other components being well mixed. It is expected that the component (A) exerts a physiologically active effect while being excellent in feeling and stability.

The polyhydric alcohol fatty acid ester of the component (D) is an organic compound having a structure in which the polyhydric alcohol and the fatty acid are ester-bonded. The component (D) is used as a component contained in the oil phase, and is obtained by emulsifying an aqueous phase containing the component (A) and an oil phase containing the component (B) so as to be mixed and homogenized by the component (C). It works to keep what is stable.

The constituent polyhydric alcohol of the component (D) is not particularly limited, and examples thereof include glycerin, pentaerythritol, BG, and neopentyl glycol. The constituent fatty acids of the component (D) are not particularly limited, and examples thereof include ethylhexanoic acid, caprylic acid, caproic acid, stearic acid, and myristic acid. In the component (D), the constituent polyhydric alcohol and the constituent fatty acid may be one of the above-mentioned ones or two or more thereof, respectively.

Since the component (D) has polarity, it can be said that it is a polar oil agent. The degree of polarity of the component (D) is not particularly limited, but for example, the IOB is preferably 0.2 or more. The IOB is an index of prohydrophobicity based on an organic conceptual diagram showing the polarity / non-polarity of an organic compound, and the organic conceptual diagram and the details of the IOB are described in, for example, Fujita's literature (A. Fujita, Pharm. Bull., 2). , 163-173 (1954)) and so on. Briefly, in the organic conceptual diagram, the source of all organic compounds is methane (CH ₄ ), and all other compounds are regarded as derivatives of methane, and their carbon numbers, substituents, transformation parts, rings, etc. are constant. Set the numerical values of, add the scores to obtain the organic value (OV) and the inorganic value (IV), and plot the organic value on the X-axis and the inorganic value on the Y-axis. Will be created. The IOB in the organic conceptual diagram means the ratio of the inorganic value (IV) to the organic value (OV) in the organic conceptual diagram, that is, "inorganic value (IV) / organic value (OV)". The larger the IOB value, the more hydrophilic, that is, the greater the polarity. The IOB value may be a numerical value published by the manufacturer, for example, published on the website [https://www.nihon-emulsion.co.jp/tech/organic.html]. Numerical values may be used.

Examples of the polyhydric alcohol fatty acid ester having an IOB of 0.2 or more include triethylhexanoin, tri (caprylic acid / capric acid) glyceryl, pentaerythrityl tetraethylhexanoate, and tri (caprylic acid / capric acid / myristic acid /). Glyceryl (stearate), neopentyl glycol dicaprate, neopentyl glycol diethylhexanoate, etc., but from the viewpoint of imparting good stability to oil-in-water emulsified cosmetics, triethylhexanoin, tri (caprylic acid / Caprylic acid) Glyceryl and pentaerythrityl tetraethylhexanoate are preferred. The polyhydric alcohol fatty acid ester may be one of these alone or a combination of two or more.

The component (D) may be extracted or synthesized by a method known so far, or may be commercially available. Examples of commercially available products include "MYRITOR GTEH" (manufactured by BASF) as triethylhexanoin, "M-fine oil CCT-1" (manufactured by Miyoshi Oil & Fat Co., Ltd.) as tri (caprylic acid / caproic acid) glyceryl. "CETIOL PEEH-4" (manufactured by BASF) as pentaerythrityl tetraethylhexanoate, "Salacos 334" (manufactured by Nisshin Oillio Group) as tri (caprylic acid / caproic acid / myristic acid / stearic acid), dicapric acid Examples of neopentyl glycol include "Estemol N-01" (manufactured by Nisshin Oillio Group), and examples of neopentyl glycol diethylhexanoate include "Cosmol 525" (manufactured by Nisshin Oillio Group), but the present invention is not limited thereto.

The content of the component (D) is not particularly limited as long as it can impart stability to the oil-in-water emulsified cosmetic, but is preferably, for example, 0.1% by mass to 15% by mass, and 1% by mass. It is more preferably% to 14% by mass, and even more preferably 3% by mass to 8% by mass. Since the content of the component (D) is within these ranges, the oil-in-water emulsified cosmetic according to one aspect of the present invention has an aqueous phase and oil even when stored at a temperature of about −10 ° C. to 45 ° C. As a mixture of phases, it can be expected to maintain its properties in a stable manner. However, the content of the component (D) can be appropriately set depending on the contents of the component (A), the component (B) and the component (C).

The water of the component (E) is used as a base for the aqueous phase. The water may be any water that is usually used for making cosmetics. The content of water is not particularly limited as long as it can constitute an oil-in-water emulsified cosmetic, but is preferably, for example, 40% by mass to 75% by mass, and 45% by mass to 70% by mass. Is more preferable, and 50% by mass to 65% by mass is more preferable.

The oil-in-water emulsified cosmetic according to one aspect of the present invention preferably has an inorganic pigment content of less than 1% by mass, preferably 0% by mass to 0.5% by mass, in order to increase the amount of oil to 15% by mass or more. %, More preferably 0% by mass to 0.3% by mass.
Further, the oil-in-water emulsified cosmetic according to one aspect of the present invention preferably has a stimulating surfactant content of 0% by mass to 0.5% by mass in order to improve the feeling of use. It is more preferably 0% by mass to 0.3% by mass.

The inorganic pigment is an inorganic powder that is insoluble in water or oil, and examples thereof include powders derived from minerals such as talc and mica.
The irritating surfactant is a surfactant known to be irritating, specifically sodium stearoylmethyltaurine and polysorbate 80. Therefore, when the oil-in-water emulsified cosmetic according to one aspect of the present invention contains stearoylmethyltaurine sodium and polysorbate 80, the total content thereof is preferably 0% by mass to 0.5% by mass, preferably 0% by mass. It is more preferably about 0.3% by mass.

The oil-in-water emulsified cosmetic according to one aspect of the present invention contains the components (A) to (E) and has a pH and hardness within a predetermined range because it is an oil-in-water emulsified cosmetic having a good usability. It is preferable to be in.

The pH of the oil-in-water emulsified cosmetic according to one aspect of the present invention is not particularly limited as long as it is a pH suitable for the oil-in-water emulsified cosmetic used on a daily basis, and is, for example, 5.0 to 8.0. It is preferably within the range, more preferably 5.5 to 7.5, and even more preferably 6.0 to 7.0.

The hardness of the oil-in-water emulsified cosmetic according to one aspect of the present invention is not particularly limited as long as it is suitable for forming various dosage forms of the oil-in-water emulsified cosmetic, but is, for example, within the range of 20 g to 300 g. It is preferably 20 g to 250 g, more preferably 30 g to 200 g.

The pH and hardness of the oil-in-water emulsified cosmetic according to one aspect of the present invention are values obtained by measuring by a method as described in Examples described later.

The oil-in-water emulsified cosmetic according to one aspect of the present invention may contain other components in addition to the components (A) to (E) as long as the problems of the present invention can be solved.

Other components are not particularly limited, and examples thereof include components used in ordinary oil-in-water emulsified cosmetics, and more specifically, oil agents, moisturizers, preservatives, thickeners, pH adjusters, and oxidations. Preservatives, refreshing agents, chelating agents, UV absorbers, UV scattering agents, whitening agents, vitamins, beauty ingredients, various other medicinal ingredients, powders, fragrances, coloring materials and the like can be mentioned. The contents of other components may be appropriately set by those skilled in the art as long as they do not interfere with solving the problems of the present invention. Some of the other components are listed below, but these are examples only and are not limited.

The oil agent is an oil agent other than the water-holding oil agent of the component (B) and the polyhydric alcohol fatty acid ester of the component (D), and has a solubility in water (1013.25 hPa, 20 ° C.) of less than 0.1% by mass (1 g / g /). A substance that is less than L). Examples of the oil agent include oil agents used as an oily emollient component capable of imparting a moisturizing function. Ester oils such as isopropyl palmitate; Silicone oils such as cyclopentasiloxane, diphenylsiloxyphenyltrimethicone, dimethicone, diphenyldimethicone, amodimethicone; Fluorine oils such as polyperfluoromethylisopropyl ether; Polyisobutene, paraffin, polyolefin, isoparaffin, squalane , Squarene and other linear and branched hydrocarbon oils; stearic acid, isostearic acid, behenic acid, undecylenic acid, palmitooleic acid, oleic acid, linoleic acid, linoleic acid, erucic acid, docosahexaenoic acid, eicosapentaenoic acid, Higher fatty acids such as isohexadecanoic acid, anteisohenicosanoic acid, long-chain branched fatty acids; cetanol, octyldodecanol, oleyl alcohol, stearyl alcohol, isostearyl alcohol, cetearyl alcohol, cetostearyl alcohol, behenyl alcohol, hexyldecanol, 2- Higher alcohols such as decyltetradecinol, monooleyl glyceryl ether (cerakil alcohol); palm oil, palm oil, palm kernel oil, safflower oil, olive oil, castor oil, avocado oil, sesame oil, brown oil, evening primrose oil, wheat Germ oil, macadamia nut oil, hazelnut oil, kukui nut oil, rose hip oil, nobara oil, meadowfoam oil, persic oil, tea tree oil, peppermint oil, corn oil, rapeseed oil, sunflower oil, wheat germ oil, flaxseed oil, cottonseed oil, Examples include soybean oil, peanut oil, rice bran oil, cacao butter, shea butter, hydrogenated palm oil, hydrogenated castor oil, jojoba oil, hydrogenated jojoba oil and other vegetable oils, one of which may be used alone or 2 Can be used in combination with more than seeds. The content of the oil agent is preferably 5% by mass to 15% by mass. Some of the UV absorbers and antioxidants described below are used as oils.

If the content of the oil agent as another component is excessive, the stability of the oil-in-water emulsified cosmetic according to one aspect of the present invention tends to be impaired. Therefore, the content of the oil agent is the component ( It is preferable that there is a certain relationship with the content of B) and / or the content of component (D). Specifically, the value of (blending amount of the oil agent) / (blending amount of the component (B) and the component (D)), which is the blending ratio of the oil agent and the component (B) and the component (D), is 0. It is preferably 1 to 2.0. If the upper limit exceeds 2.0, problems such as difficulty in mixing and emulsifying the aqueous phase and the oil phase and difficulty in ensuring stability over time tend to occur.

The total content of the oil component (B), the component (D) and the oil agent in the oil-in-water emulsified cosmetic according to one aspect of the present invention has a good moisturizing effect on the oil-in-water emulsified cosmetic according to one aspect of the present invention. From the viewpoint that the oil-in-water emulsified cosmetic according to one aspect of the present invention has a better moisturizing effect, it is 15% by mass to 40% by mass. , 20% by mass to 40% by mass, more preferably 20% by mass to 30% by mass.

Examples of the moisturizing agent include glycerin, butylene glycol (BG), propylene glycol (PG), diglycerin, dipropylene glycol (DPG), methylglyces-10, methylglyces-20, and PEG / PPG / polybutylene glycol-8 / 5. / 3 Glycerin, trehalose, xylitol, marttoll, maltose, sorbitol, glucose, fructose, hydrolyzed elastin, sodium lactate, cyclodextrin, pyrrolidone carboxylic acid, etc., one of which may be used alone or in combination of two or more. Can be used in combination. The content of the moisturizer is preferably 0% by mass to 15% by mass.

Examples of preservatives include methyl paraoxybenzoate (methylparaben), phenoxyethanol, benzoic acid, salicylic acid, phenolic acid, sorbic acid, parachlormethacresol, hexachlorophen, benzalkonium chloride, chlorhexidine chloride, trichlorocarbanilide, and photosensitizers. Etc., and one of these can be used alone or in combination of two or more. The content of the preservative is preferably 0% by mass to 1% by mass.

Examples of the thickener include water-soluble polymers, and specific examples thereof include hyaluronic acid, sodium hyaluronate, acetylated hyaluronic acid, acetylated sodium hyaluronate, xanthan gum, chondroitin sulfate, sodium chondroitin sulfate, and fucoidan. , Water-soluble polysaccharides such as tuberose polysaccharides; Natural polymers such as carrageenan and alginic acid; Semi-synthetic polymers such as sodium carboxymethyl cellulose; Carbomer, polyacrylic acid, sodium polyacrylic acid, (meth) acrylic acid / (meth) Examples thereof include synthetic polymers such as acrylic acid-based polymers such as alkyl acrylate copolymers. The thickener may be used alone or in combination of two or more. The content of the thickener is preferably 0% by mass to 1% by mass.

Examples of the pH adjuster include lactic acid, citric acid, glycolic acid, succinic acid, tartaric acid, malic acid, sodium malate, ethidronic acid, potassium carbonate, sodium hydrogencarbonate, ammonium hydrogencarbonate, sodium hydroxide, potassium hydroxide, and the like. Examples thereof include arginine, triethanolamine, monoethanolamine and the like, and one of these can be used alone or in combination of two or more. The content of the pH adjuster is preferably 0% by mass to 1% by mass. The pH regulator is also called a neutralizer.

Examples of the antioxidant include vitamin E and its derivatives such as dibutylhydroxytoluene, butylhydroxyanisole, and δ-tocopherol; thiotaurine, mematsuyoigusa extract, β-carotene, catechin compound, flavonoid compound, polyphenol compound, sodium pyrosulfate and the like. These can be used alone or in combination of two or more. The content of the antioxidant is preferably 0% by mass to 1% by mass.

Examples of the chelating agent include alanine, disodium edetate, sodium polyphosphate, sodium metaphosphate, sodium phytate, trisodium phosphate and the like, and one of these may be used alone or in combination of two or more. Can be used. The content of the chelating agent is preferably about 0% by mass to 0.1% by mass.

Examples of beauty ingredients include apple tannin, citrus root extract, resveratrol, tuberose polysaccharide, high fructose corn syrup, noni juice, chimpi extract, dipotassium glycyrrhizinate, etc., and one of these may be used alone or in two. The above can be used in combination. The content of the beauty ingredient is preferably 0% by mass to 5% by mass.

The oil-in-water emulsified cosmetic according to one aspect of the present invention is not particularly limited in its function and / or effect as long as it is used as a cosmetic. The oil-in-water emulsified cosmetic according to one aspect of the present invention has good usability and stability.

The feeling of use of the oil-in-water emulsified cosmetic according to one aspect of the present invention is, for example, to directly apply the test cosmetic to the inside of the forearm of five trained panelists by the sensory evaluation described in Examples described later. When applied to the skin, the average score of irritation or stickiness is preferably greater than 3.0, and the average score of both irritation and stickiness is more preferably greater than 3.0.

The stability of the oil-in-water emulsified cosmetic according to one aspect of the present invention is, for example, stored in a constant temperature bath at 45 ° C. or a low temperature cycle for one month or one week by the method described in Examples described later. It is preferable that the whole cosmetic is uniform and no crystals, agglomerates or rough textures are confirmed when it is stretched on an acrylic plate. It is more preferable that the whole cosmetic is uniform when stored for months or one week, and no crystals, agglomerates or rough textures are confirmed when the cosmetic is spread on an acrylic plate.

A specific aspect of the oil-in-water emulsified cosmetic according to one aspect of the present invention is that the component (A) is 3% by mass to 8% by mass, the component (B) is 1.5% by mass to 15% by mass, and the component (C). ) Is contained in an amount of 0.4% by mass to 8% by mass, the component (D) is contained in an amount of 1% by mass to 14% by mass, and the component (E) is contained in an amount of 40% by mass to 75% by mass. By 40% by mass, the pH is 5.5 to 7.5, and the hardness is 20 g to 250 g, the irritation feeling is reduced while containing a high concentration of nicotinic acid amide, and the oil content is reduced. It is an oil-in-water emulsified cosmetic that does not feel sticky even when the total amount is 15% by mass or more and has a good overall usability.

Another specific aspect of the oil-in-water emulsified cosmetic according to one aspect of the present invention is that the component (A) is 4% by mass to 7% by mass, the component (B) is 1.5% by mass to 12% by mass, and the component. (C) is contained in an amount of 0.6% by mass to 3% by mass, component (D) is contained in an amount of 3% by mass to 8% by mass, and component (E) is contained in an amount of 50% by mass to 65% by mass, and the total oil content is 20% by mass. By having a% to 40% by mass, a pH of 6.0 to 7.0, and a hardness of 30 g to 200 g, the irritation feeling is reduced while containing a high concentration of nicotinic acid amide. It is an oil-in-water emulsified cosmetic that does not feel sticky even when the total amount of oil is 15% by mass or more, has a good overall usability, and has good stability.

The oil-in-water emulsified cosmetic according to one aspect of the present invention is obtained by mixing and emulsifying the components (A) to (E) and any other components. Another aspect of the present invention is the method for producing an oil-in-water emulsified cosmetic according to another aspect of the present invention.

In the method of one aspect of the present invention, the component (C) and the oil phase containing the component (B) and the component (D) are sequentially added to the aqueous phase containing the component (A) and the component (E). The present invention comprises the step of obtaining an oil-in-water emulsified cosmetic according to one aspect of the present invention by emulsifying.

As a non-limiting specific example of the method of one aspect of the present invention, an aqueous phase containing the component (A) and the component (E) by heating to 60 ° C. to 90 ° C., respectively, and the component (B) and the component ( An oil phase containing D) is prepared, then the component (B) is added to the aqueous phase, and a high-speed stirrer is used at 60 ° C. to 90 ° C. at 2,000 rpm to 4,000 rpm for several minutes. The oil phase is added to the aqueous phase containing the component (B), and the oil phase is added to the aqueous phase containing the component (B), and the oil phase is added to the aqueous phase containing the component (B) at 60 ° C. to 90 ° C. at 2,000 rpm to 4,000 rpm. The emulsified product was obtained by subjecting it to a second high-speed stirring treatment for several minutes, and then the emulsified product was cooled to about 50 ° C. with gentle stirring, and the pH was adjusted to 6 to 7. Then, a method of obtaining an oil-in-water emulsified cosmetic according to one aspect of the present invention can be mentioned by cooling the emulsified product after adjusting the pH to about room temperature to about 30 ° C. with gentle stirring. Any other component may be included in the aqueous phase or the oil phase depending on the respective properties (water-soluble or fat-soluble).

According to the method of one aspect of the present invention, an oil-in-water emulsified cosmetic according to one aspect of the present invention can be obtained by sequentially adding an acrylamide-based polymer and an oil phase to an aqueous phase and emulsifying them. Since it can be easily carried out without preparing a complicated process or a special device, it is possible to produce the oil-in-water emulsified cosmetic according to one aspect of the present invention on an industrial scale.

The oil-in-water emulsified cosmetic according to one aspect of the present invention is not particularly limited in its usage mode and dosage form, and is, for example, skin care cosmetics, makeup cosmetics, fragrance cosmetics, body care cosmetics, etc., specifically creams and emulsions. , Foundation, lotion, beauty liquid, sunscreen milk, pack, face wash cream, hand cream, makeup cleansing, makeup base, concealer, cheeks, eye shadow, eyeliner, eyebrow, lipstick, sunscreen cream, hair removal / hair removal It can be applied to creams, all-in-one cosmetics, etc. The oil-in-water emulsified cosmetic according to one aspect of the present invention has excellent stability and a moist and good feeling of use by forming a dosage form having a certain viscosity such as a milky lotion, a cream, and a beauty essence. It is preferable because it can be obtained. In particular, it is more preferable to use a dosage form for partial use such as eye cream because it has a certain hardness and an excellent feeling of use. It should be noted that the dosage form for partial use such as eye cream is harder than the milky lotion or cream for applying to the entire face because the richness at the time of application is required. Further, the oil-in-water emulsified cosmetic according to one aspect of the present invention can be impregnated into a sheet or the like, sprayed or the like. Therefore, the oil-in-water emulsified cosmetic according to one aspect of the present invention is expected to be in a dosage form such as an impregnated sheet, an impregnated mask, or a spray such as a pump.

The oil-in-water emulsified cosmetic according to one aspect of the present invention is expected to exert various physiological and pharmacological effects due to the physiological activity of nicotinamide when applied to the skin. The method for applying the oil-in-water emulsified cosmetic according to the present invention to the skin is not particularly limited. For example, the oil-in-water emulsified cosmetic according to the present invention is applied to the skin with a finger or an application tool. Examples include a method of stretching and a method of applying using a dedicated applicator built in the container. Further, the oil-in-water emulsified cosmetic according to one aspect of the present invention can prevent water evaporation from the skin surface due to the moisturizing action of the oil component. Further, the oil-in-water emulsified cosmetic according to one aspect of the present invention can improve the applied dry skin or suppress deterioration due to further drying by containing water and a moisturizing agent.

Hereinafter, the present invention will be described in more detail by way of examples, but the present invention is not limited to these examples, and the present invention may take various aspects as long as the problems of the present invention can be solved. can.

[1. Preparation of oil-in-water emulsified cosmetics (1)]
According to the prescription shown in Table 1, various oil-in-water emulsified cosmetics were prepared as test cosmetics according to the following procedure. The numerical values in the table represent mass% (wt%).

Each of the aqueous phase and the oil phase in the table was prepared by dissolving, mixing and stirring each component at 80 ° C. to make them uniform. Next, an acrylamide-based polymer is added to the aqueous phase, and the mixture is stirred and mixed at 80 ° C., 3,000 rpm, and 1 minute using a disper (“Lab Solution”; manufactured by Primix) to increase the acrylamide-based height. A molecular-containing aqueous phase was prepared. Next, an oil phase was added to the acrylamide-based polymer-containing aqueous phase, and the mixture was stirred and mixed at 80 ° C., 3,000 rpm, and 1 minute under the conditions of 80 ° C., 3,000 rpm, and subjected to emulsification treatment to obtain an emulsified product. ..

The obtained emulsified product was cooled to 50 ° C. with gentle stirring using a paddle, and then the pH was adjusted to 6 to 7 by adding a neutralizing agent. Then, the pH-adjusted emulsified product was cooled to 30 ° C. with gentle stirring to obtain a test cosmetic.

[2. Evaluation method]
(2-1) pH
For the pH, use a pH meter (“pH MTER F-22”; manufactured by HORIBA, Ltd.) for the test cosmetics placed in a 100 ml jar container (manufactured by Takemoto Container Co., Ltd.) and allowed to stand overnight at 20 ° C. And measured.

(2-2) Hardness The test cosmetic was placed in a 100 ml jar container (manufactured by Takemoto Yohki Co., Ltd.) and allowed to stand at 20 ° C. overnight. Then, the hardness of the test cosmetics that had been allowed to stand was measured using a leometer (“CR-500DX”; manufactured by Sun Scientific Co., Ltd.).

(2-3) Emulsification The layer separation occurred during the emulsification treatment by visually observing the test cosmetics produced during one day in an environment of 20 ° C. from the emulsification treatment at the time of production. The emulsifying property was evaluated according to the following criteria, using the abnormalities of oil floating during cooling and / or the occurrence of crystals, aggregates, or coarse texture in the cosmetic after production as indicators. ..
◯: The above abnormality is not observed ×: Due to the above abnormality, a uniform test cosmetic cannot be manufactured.

(2-4) Stability Put the test cosmetics in a 7K bottle (manufactured by Tokyo Glass Co., Ltd.) and store them in a constant temperature bath at 45 ° C and a low temperature cycle (-10 ° C to 10 ° C) for 1 month. did. By visually confirming the condition of the cosmetics after storage, the stability was evaluated according to the following criteria.
◯: The whole cosmetic is uniform, and no crystals, aggregates or rough texture are confirmed when the cosmetic is stretched on the acrylic plate. ×: Crystals are separated when the cosmetic is separated or the cosmetic is stretched on the acrylic plate. , Aggregates or coarse texture are confirmed

(2-5) Sensory evaluation For 5 trained panelists, by applying the test cosmetics directly to the skin on the inside of the forearm, the following criteria are used for the feeling of irritation (stinging) and stickiness. The average score and standard deviation between the panelists were calculated by scoring. In addition, as a comprehensive evaluation of these, the usability was evaluated according to the following criteria.

<Stimulation>
5: I don't feel a tingling stimulus 4: I don't feel a tingling stimulus so much 3: I don't have a stimulus, but I feel a sense of discomfort 2: I feel a tingling stimulus a little 1: I feel a tingling stimulus

<Stickiness>
5: No oiliness and no stickiness 4: No oiliness but slightly sticky 3: Slightly oily and slightly sticky 2: Slightly oily and sticky 1: Oily feeling Is strong and feels sticky

<Usage>
◯: The average score of both irritation and stickiness is greater than 3.0 ×: The average score of at least one of irritation and stickiness is 3.0 or less.

[3. Evaluation results]
The results of various measurements are shown in Table 1.
The test cosmetics of Examples 1 to 6 contain an acrylamide polymer, a water-holding oil agent, and a polyhydric alcohol fatty acid ester while containing a high concentration of nicotinic acid amide of 5% by mass, so that the oil-in-water emulsified makeup. It was obtained as a material and had excellent usability and stability.

On the other hand, the test cosmetic containing no acrylamide polymer was inferior in emulsifying property and could not be used as an oil-in-water emulsified cosmetic (Comparative Example 1). On the other hand, the test cosmetic containing a high concentration of a non-polar oil instead of the polyhydric alcohol fatty acid ester was able to be emulsified, but was inferior in stability and sticky (Comparative Example 2).

The test cosmetics containing no nicotinamide had no problem with irritation (Reference Example 1), but those containing a surfactant together with nicotinamide showed irritation (Comparative Example 3 and). Comparative Example 4). On the other hand, when soap emulsification had to be used, the emulsification treatment was not performed properly, and the obtained product had aggregates in the cosmetics and could not be used as a normal oil-in-water emulsified cosmetic. (Comparative Example 5). The test cosmetics of Comparative Example 5 did not conform to the standard, but when evaluated for reference, a feeling of irritation was observed.

It was found that the obtained test cosmetics tended to be inferior in stability depending on the contents of the acrylamide polymer, the water-holding oil agent and the polyhydric fatty acid ester (Comparative Example 6, Comparative Example 7 and Comparison). Example 8). Further, it was found that the test cosmetics having an excessive content of nicotinamide had a poor usability (Comparative Example 9).

[4. Preparation of oil-in-water emulsified cosmetics (2) and evaluation]
In the same manner as in 1 above, various oil-in-water emulsified cosmetics were prepared as test cosmetics according to the formulations shown in Table 2. In addition, the pH, hardness, emulsifying property and stability of the obtained test cosmetics were measured by the method shown in 2 above, and a sensory evaluation was carried out. However, for stability, it was stored for one week instead of being stored for one month. The results of various measurements are shown in Table 2.

As shown in Table 2, the content of the nicotinic acid amide is as large as 3% by mass to 8% by mass, but the content of the water-holding oil is 2% by mass to 12% by mass, and the acrylamide-based polymer (copolymer) is used. ) Is 1.5% by mass to 3% by mass (amount of raw materials), and the oil-in-water emulsified cosmetic containing a polyhydric alcohol fatty acid ester is expected to have physiological activity due to nicotinic acid amide. However, it was found to be excellent in usability and stability (Examples 7 to 12). Furthermore, these oil contents were as high as 16.25% by mass to 27.48% by mass.

In addition, the oil-in-water emulsified cosmetics containing polysorbate 80, which is said to be irritating, but having a small content of 0.3% by mass, did not give a feeling of irritation (Example 11).

[5. Preparation of oil-in-water emulsified cosmetics (3) and evaluation]
In the same manner as in 1 above, various oil-in-water emulsified cosmetics were prepared as test cosmetics according to the formulations shown in Table 3. In addition, the pH, hardness, emulsifying property and stability of the obtained test cosmetics were measured by the method shown in 2 above, and a sensory evaluation was carried out. The results of various measurements are shown in Table 3.

As shown in Table 3, the test cosmetics of Example 13 were excellent in both usability and stability.

From the results in Tables 1 to 3, in addition to the nicotinic acid amide, the oil-in-water emulsified cosmetics containing polyhydric alcohol fatty acid ester and water, as well as the acrylamide-based polymer and water-holding oil prepared in predetermined amounts, respectively. It was found that while the physiological activity of nicotinic acid amide can be expected, the oil content is high and the feeling of use and stability are excellent.

Among the ingredients in the table, the product names used are excerpted and shown below.
(Acrylate / Alkyl Acrylate (C10-30)) Cross Polymer: "Pemmulen ^TM TR-2" (manufactured by Lubrizol Advanced Materials)
Carbomer (980): "Carbopol® 980 Polymer" (manufactured by Lubrizol Advanced Materials)
Carbomer (MD-105): "HIVISWAKO (registered trademark) MD-105" (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd.)
Stearoyl Methyl Taurine Na: "NIKKOL SMT" (manufactured by Nikko Chemicals Co., Ltd.)
37.5% (Na Acrylate / Acryloyldimethyltaurine Na) Copolymer / Isohexadecane / Polysorbate 80 / Water Mix: "SIMULGEL ^TM EG" (Copolymer Content 37.5%; Isohexadecane (Content 22.5%), Contains polysorbate 80 (content 7.5%), sorbitan monooleate (content 2.5%), water; manufactured by SEPPIC)
40% Polyacrylamide / (C13,14) Isoparaffin / Laures-7 / Water Mixture: "SEPIGEL 305" (Polyacrylamide content 40%; (C13,14) Isoparaffin (content 24%), Laures-7 (content) 6%), contains water; manufactured by SEPPIC)
Di (phytosteryl / octyldodecyl) lauroyl glutamate: "Eldu (registered trademark) PS-203" (manufactured by Ajinomoto Co., Inc.)
Dipentaerythrityl tripolyhydroxystearate: "Saracos WO-6" (manufactured by Nisshin Oillio Group)
Macadamia nut fatty acid phytosteryl: "PLANDOOL ^TM -MAS" (manufactured by Nippon Fine Chemical Co., Ltd.)
Triethylhexanoin: "MYRITOR GTEH" (manufactured by BASF)
Pentaerythrityl tetraethylhexanoate: "CETIOL PEEH-4" (manufactured by BASF)
Tri (caprylic acid / capric acid) glyceryl: "M-Fine Oil CCT-1" (manufactured by Miyoshi Oil & Fat Co., Ltd.)
Stearic acid: "NAA-173K" (manufactured by NOF CORPORATION)
Polysorbate 80: "Leodor TW-O120V" (manufactured by Kao Corporation)
L-arginine, water: "L-arginine C grade" (manufactured by Ajinomoto Co., Inc.) adjusted to 10% with purified water Potassium hydroxide, water: "potassium hydroxide" (manufactured by Kanto Chemical Co., Ltd.) purified water Adjusted to 10%

The oil-in-water emulsified cosmetic according to one aspect of the present invention has a bioactive effect due to nicotinic acid amide and a moisturizing effect due to the oil content, but has a good usability and excellent stability. , Cream, emulsion, lotion, beauty essence, impregnation sheet, impregnation mask, spray and other skin care cosmetics. The user is expected to reduce or prevent dryness of the skin while promoting blood circulation and ceramide synthesis of the skin comfortably on a daily basis by using the oil-in-water emulsified cosmetic according to one aspect of the present invention. can.

Claims (8)

An oil-in-water emulsified cosmetic containing nicotinic acid amide, a water-holding oil, an acrylamide polymer, a polyhydric alcohol fatty acid ester, and water.
The content of the nicotinamide is 3% by mass to 8% by mass.
The content of the water-holding oil is 1.5% by mass to 15% by mass, and the content is 1.5% by mass to 15% by mass.
The content of the acrylamide-based polymer is 0.5% by mass to 8% by mass in the case of the acrylamide-based polymer of the copolymer, and 0.4% by mass or more in the case of the acrylamide-based polymer of the homopolymer. It is 8% by weight and the total oil content is 15% to 40% by weight.
The oil-in-water emulsified cosmetic. The oil-in-water emulsified cosmetic according to claim 1, wherein the oil-in-water emulsified cosmetic has an inorganic pigment content of less than 1% by mass. The oil-in-water emulsified cosmetic has a total content of a stimulating surfactant selected from the group consisting of sodium stearoylmethyltaurine and polysorbate 80 of 0% by mass to 0.5% by mass, according to claims 1 and 2. The oil-in-water emulsified cosmetic according to any one of the following items. The oil-in-water emulsified cosmetic according to any one of claims 1 to 3, wherein the water-holding oil is at least one water-holding oil selected from the group consisting of a phytosterol derivative and a polyhydric alcohol hydroxy fatty acid ester. .. The phytosterol derivatives are dilauroyl glutamate (phytosteryl / octyldodecyl), dilauroyl glutamate (octyldodecyl / phytosteryl / behenyl), macadamia nut fatty acid phytosteryl, dimer dilinoleic acid (phytosteryl / isostearyl / cetyl / stearyl / behenyl), isostearic acid. At least one phytosterol derivative selected from the group consisting of phytosteryl and phytosteryl hydroxystearate, and / or the polyhydric alcohol hydroxy fatty acid ester is dipentaerythrityl tripolyhydroxystearate and hexa (hydroxystearic acid / stearic acid / loginic acid). ) The oil-in-water emulsified cosmetic according to claim 4, which is at least one polyhydric alcohol hydroxy fatty acid ester selected from the group consisting of dipentaerythrityl. The acrylamide polymer is at least one acrylamide polymer selected from the group consisting of a (sodium acrylate / sodium acryloyldimethyltaurine) copolymer, a (hydroxyethyl acrylate / sodium acryloyldimethyltaurine) copolymer and polyacrylamide. , The oil-in-water emulsified cosmetic according to any one of claims 1 to 5. The polyhydric alcohol fatty acid ester includes triethylhexanoin, pentaerythrityl tetraethylhexanoate, tri (caprylic acid / capric acid) glyceryl, tri (caprylic acid / capric acid / myristic acid / stearic acid) glyceryl, and neopentyl glycol dicaprate. The oil-in-water emulsified cosmetic according to any one of claims 1 to 6, which is at least one polyhydric alcohol ester selected from the group consisting of neopentyl glycol diethylhexanoic acid. The content of the polyhydric alcohol fatty acid ester is 1% by mass to 14% by mass, and / or the content of the water is 40% by mass to 75% by mass, according to any one of claims 1 to 7. The described underwater oil type emulsified cosmetic.