JP2022078265A5 - - Google Patents
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- JP2022078265A5 JP2022078265A5 JP2022037781A JP2022037781A JP2022078265A5 JP 2022078265 A5 JP2022078265 A5 JP 2022078265A5 JP 2022037781 A JP2022037781 A JP 2022037781A JP 2022037781 A JP2022037781 A JP 2022037781A JP 2022078265 A5 JP2022078265 A5 JP 2022078265A5
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- Japan
- Prior art keywords
- pharmaceutical composition
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- antibody
- antigen
- binding fragment
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023190525A JP7656012B2 (ja) | 2017-02-21 | 2023-11-08 | 肺癌の処置のための抗ｐｄ－１抗体 |
| JP2025044340A JP2025098103A (ja) | 2017-02-21 | 2025-03-19 | 肺癌の処置のための抗ｐｄ－１抗体 |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762461672P | 2017-02-21 | 2017-02-21 | |
| US62/461,672 | 2017-02-21 | ||
| US201762595190P | 2017-12-06 | 2017-12-06 | |
| US62/595,190 | 2017-12-06 | ||
| JP2019545324A JP7324710B2 (ja) | 2017-02-21 | 2018-02-20 | 肺癌の処置のための抗ｐｄ－１抗体 |
| PCT/US2018/018747 WO2018156494A1 (en) | 2017-02-21 | 2018-02-20 | Anti-pd-1 antibodies for treatment of lung cancer |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019545324A Division JP7324710B2 (ja) | 2017-02-21 | 2018-02-20 | 肺癌の処置のための抗ｐｄ－１抗体 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023190525A Division JP7656012B2 (ja) | 2017-02-21 | 2023-11-08 | 肺癌の処置のための抗ｐｄ－１抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022078265A JP2022078265A (ja) | 2022-05-24 |
| JP2022078265A5 true JP2022078265A5 (https=) | 2022-09-05 |
| JP7384949B2 JP7384949B2 (ja) | 2023-11-21 |
Family
ID=61628468
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019545324A Active JP7324710B2 (ja) | 2017-02-21 | 2018-02-20 | 肺癌の処置のための抗ｐｄ－１抗体 |
| JP2022037781A Active JP7384949B2 (ja) | 2017-02-21 | 2022-03-11 | 肺癌の処置のための抗ｐｄ－１抗体 |
| JP2023190525A Active JP7656012B2 (ja) | 2017-02-21 | 2023-11-08 | 肺癌の処置のための抗ｐｄ－１抗体 |
| JP2025044340A Pending JP2025098103A (ja) | 2017-02-21 | 2025-03-19 | 肺癌の処置のための抗ｐｄ－１抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019545324A Active JP7324710B2 (ja) | 2017-02-21 | 2018-02-20 | 肺癌の処置のための抗ｐｄ－１抗体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023190525A Active JP7656012B2 (ja) | 2017-02-21 | 2023-11-08 | 肺癌の処置のための抗ｐｄ－１抗体 |
| JP2025044340A Pending JP2025098103A (ja) | 2017-02-21 | 2025-03-19 | 肺癌の処置のための抗ｐｄ－１抗体 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US11292842B2 (https=) |
| EP (1) | EP3585812A1 (https=) |
| JP (4) | JP7324710B2 (https=) |
| KR (2) | KR102628557B1 (https=) |
| CN (2) | CN110536905B (https=) |
| AU (2) | AU2018225102B2 (https=) |
| CA (1) | CA3054289A1 (https=) |
| IL (3) | IL321717A (https=) |
| MA (1) | MA47604A (https=) |
| MX (2) | MX2019009772A (https=) |
| WO (1) | WO2018156494A1 (https=) |
| ZA (1) | ZA201905051B (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160053301A1 (en) | 2014-08-22 | 2016-02-25 | Clearfork Bioscience, Inc. | Methods for quantitative genetic analysis of cell free dna |
| EP4458417A3 (en) | 2015-08-11 | 2025-02-19 | Wuxi Biologics Ireland Limited | Novel anti-pd-1 antibodies |
| US11319594B2 (en) | 2016-08-25 | 2022-05-03 | Resolution Bioscience, Inc. | Methods for the detection of genomic copy changes in DNA samples |
| JP7066696B2 (ja) | 2016-10-11 | 2022-05-13 | アジェナス インコーポレイテッド | 抗ｌａｇ－３抗体及びその使用方法 |
| MA47604A (fr) * | 2017-02-21 | 2020-01-01 | Regeneron Pharma | Anticorps anti-pd-1 pour le traitement du cancer du poumon |
| US11389525B2 (en) * | 2017-10-27 | 2022-07-19 | Statens Serum Institut | Polygene influenza vaccine |
| EP3853247A2 (en) | 2018-09-19 | 2021-07-28 | Alpine Immune Sciences, Inc. | Methods and uses of variant cd80 fusion proteins and related constructs |
| SI3880186T1 (sl) | 2018-11-14 | 2024-07-31 | Regeneron Pharmaceuticals, Inc., | Intralezijska uporaba zaviralcev PD-1 za zdravljenje kožnega raka |
| WO2020154187A1 (en) * | 2019-01-21 | 2020-07-30 | Sanofi | Therapeutic rna for advanced stage solid tumor cancers |
| MA55084A (fr) * | 2019-02-28 | 2022-01-05 | Regeneron Pharma | Administration d'inhibiteurs de pd-1 pour le traitement du cancer de la peau |
| MX2021010560A (es) | 2019-03-06 | 2021-11-12 | Regeneron Pharma | Inhibidores de la via il-4/il-13 para una eficacia aumentada en el tratamiento de cancer. |
| US20230054413A1 (en) * | 2019-12-13 | 2023-02-23 | Samsung Bioepis Co., Ltd. | Stable anti-pd1 antibody pharmaceutical formulations |
| CN113244385A (zh) * | 2020-02-07 | 2021-08-13 | 上海君实生物医药科技股份有限公司 | 抗pd-1抗体在治疗恶性肿瘤中的用途 |
| ES3014683T3 (en) * | 2020-03-13 | 2025-04-24 | Univ Texas | Sequential treatment of cancers using 6-thio-dg and checkpoint inhibitors |
| EP4297782A1 (en) * | 2021-02-23 | 2024-01-03 | Regeneron Pharmaceuticals, Inc. | Methods of treating lung cancer by administering a pd-1 inhibitor |
| WO2023185720A1 (zh) * | 2022-03-28 | 2023-10-05 | 齐鲁制药有限公司 | 包含抗ctla4和抗pd1的混合抗体的药物组合物及其治疗用途 |
| WO2024077069A1 (en) * | 2022-10-05 | 2024-04-11 | Chulalongkorn University | Monoclonal antibodies against human programmed cell death protein 1 (pd-1) |
| WO2025030110A1 (en) * | 2023-08-02 | 2025-02-06 | Sensei Biotherapeutics, Inc. | Cancer therapies targeting vista as monotherapy or in combination with anti-pd1 antibody to treat cancer |
| WO2025159618A1 (ko) | 2024-01-24 | 2025-07-31 | 주식회사 엘지에너지솔루션 | 전극탭 용접장치 및 전극탭 용접방법 |
| TW202602455A (zh) | 2024-03-26 | 2026-01-16 | 美商安進公司 | 使用ｍｔａ協作的ｐｒｍｔ５抑制劑的癌症治療 |
| WO2025213154A1 (en) | 2024-04-05 | 2025-10-09 | Amgen Inc. | Gastrointestinal cancer treatments using mta-cooperative prmt5 inhibitors |
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| US7087411B2 (en) | 1999-06-08 | 2006-08-08 | Regeneron Pharmaceuticals, Inc. | Fusion protein capable of binding VEGF |
| PL354286A1 (en) | 1999-08-23 | 2003-12-29 | Dana-Farber Cancer Institutedana-Farber Cancer Institute | Pd-1, a receptor for b7-4, and uses therefor |
| US7794710B2 (en) | 2001-04-20 | 2010-09-14 | Mayo Foundation For Medical Education And Research | Methods of enhancing T cell responsiveness |
| CN101899114A (zh) | 2002-12-23 | 2010-12-01 | 惠氏公司 | 抗pd-1抗体及其用途 |
| US7563869B2 (en) | 2003-01-23 | 2009-07-21 | Ono Pharmaceutical Co., Ltd. | Substance specific to human PD-1 |
| PT2343320T (pt) | 2005-03-25 | 2018-01-23 | Gitr Inc | Anticorpos anti-gitr e as suas utilizações |
| DK2439273T3 (da) | 2005-05-09 | 2019-06-03 | Ono Pharmaceutical Co | Humane monoklonale antistoffer til programmeret død-1(pd-1) og fremgangsmåder til behandling af cancer ved anvendelse af anti-pd-1- antistoffer alene eller i kombination med andre immunterapeutika |
| PT1907424E (pt) | 2005-07-01 | 2015-10-09 | Squibb & Sons Llc | Anticorpos monoclonais humanos para o ligando 1 de morte programada (pd-l1) |
| BR122017025062B8 (pt) | 2007-06-18 | 2021-07-27 | Merck Sharp & Dohme | anticorpo monoclonal ou fragmento de anticorpo para o receptor de morte programada humano pd-1, polinucleotídeo e composição compreendendo o referido anticorpo ou fragmento |
| US8591886B2 (en) | 2007-07-12 | 2013-11-26 | Gitr, Inc. | Combination therapies employing GITR binding molecules |
| EP2195342A1 (en) | 2007-09-07 | 2010-06-16 | Ablynx N.V. | Binding molecules with multiple binding sites, compositions comprising the same and uses thereof |
| EP2262837A4 (en) | 2008-03-12 | 2011-04-06 | Merck Sharp & Dohme | PD-1 BINDING PROTEINS |
| AU2009288730B2 (en) | 2008-08-25 | 2013-06-20 | Amplimmune, Inc. | Compositions of PD-1 antagonists and methods of use |
| EP3255060A1 (en) | 2008-12-09 | 2017-12-13 | F. Hoffmann-La Roche AG | Anti-pd-l1 antibodies and their use to enhance t-cell function |
| KR101790802B1 (ko) | 2009-09-03 | 2017-10-27 | 머크 샤프 앤드 돔 코포레이션 | 항-ｇｉｔｒ 항체 |
| PL2504364T3 (pl) | 2009-11-24 | 2017-12-29 | Medimmune Limited | Ukierunkowane środki wiążące przeciwko B7-H1 |
| TW201134488A (en) | 2010-03-11 | 2011-10-16 | Ucb Pharma Sa | PD-1 antibodies |
| WO2011159877A2 (en) | 2010-06-18 | 2011-12-22 | The Brigham And Women's Hospital, Inc. | Bi-specific antibodies against tim-3 and pd-1 for immunotherapy in chronic immune conditions |
| CA2840018C (en) | 2011-07-24 | 2019-07-16 | Curetech Ltd. | Variants of humanized immunomodulatory monoclonal antibodies |
| MX368257B (es) | 2011-08-01 | 2019-09-26 | Genentech Inc | Antagonistas de unión al eje pd-1e inhibidores de mek y sus usos en el tratamiento de cáncer. |
| EP3511343A1 (en) | 2012-05-04 | 2019-07-17 | Dana Farber Cancer Institute, Inc. | Affinity matured anti-ccr4 humanized monoclonal antibodies and methods of use |
| GB2519273B (en) | 2012-07-23 | 2019-12-11 | Silgan Dispensing Systems Corp | Aerosol actuators,with extended triggers |
| JOP20200236A1 (ar) | 2012-09-21 | 2017-06-16 | Regeneron Pharma | الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها |
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| US10241115B2 (en) | 2013-12-10 | 2019-03-26 | Merck Sharp & Dohme Corp. | Immunohistochemical proximity assay for PD-1 positive cells and PD-ligand positive cells in tumor tissue |
| IL263466B2 (en) | 2013-12-17 | 2023-10-01 | Genentech Inc | Anti-CD3 antibodies and methods of using them |
| TWI681969B (zh) | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對ｐｄ-１的人類抗體 |
| TWI680138B (zh) | 2014-01-23 | 2019-12-21 | 美商再生元醫藥公司 | 抗ｐｄ-ｌ１之人類抗體 |
| PE20170255A1 (es) | 2014-01-24 | 2017-03-22 | Dana Farber Cancer Inst Inc | Moleculas de anticuerpo que se unen a pd-1 y usos de las mismas |
| TWI701042B (zh) | 2014-03-19 | 2020-08-11 | 美商再生元醫藥公司 | 用於腫瘤治療之方法及抗體組成物 |
| WO2015176033A1 (en) * | 2014-05-15 | 2015-11-19 | Bristol-Myers Squibb Company | Treatment of lung cancer using a combination of an anti-pd-1 antibody and another anti-cancer agent |
| SI3148579T1 (sl) | 2014-05-28 | 2021-07-30 | Agenus Inc. | Proti GITR antitelesa in postopki z njihovo uporabo |
| PE20170441A1 (es) | 2014-06-06 | 2017-04-26 | Bristol Myers Squibb Co | Anticuerpos contra el receptor del factor de necrosis tumoral inducido por glucocorticoides (gitr) y sus usos |
| US10092645B2 (en) | 2014-06-17 | 2018-10-09 | Medimmune Limited | Methods of treatment with antagonists against PD-1 and PD-L1 in combination with radiation therapy |
| IL287519B2 (en) | 2014-06-19 | 2024-01-01 | Regeneron Pharma | Non-human animals having a humanized programmed cell death 1 gene |
| BR112017011536A2 (pt) * | 2014-12-02 | 2018-02-27 | Celgene Corp | terapias de combinação |
| ES2791950T3 (es) | 2015-02-03 | 2020-11-06 | Ventana Med Syst Inc | Ensayo histoquímico para evaluar la expresión del ligando de muerte programada 1 (PD-L1) |
| CN108112254B (zh) | 2015-03-13 | 2022-01-28 | 西托姆克斯治疗公司 | 抗-pdl1抗体、可活化的抗-pdl1抗体、及其使用方法 |
| KR20250004095A (ko) * | 2015-04-17 | 2025-01-07 | 브리스톨-마이어스 스큅 컴퍼니 | 항-pd-1 항체 및 또 다른 항체의 조합물을 포함하는 조성물 |
| ES2835866T5 (es) * | 2015-05-12 | 2024-12-02 | Hoffmann La Roche | Procedimientos terapéuticos y de diagnóstico para el cáncer |
| US20180155429A1 (en) * | 2015-05-28 | 2018-06-07 | Bristol-Myers Squibb Company | Treatment of pd-l1 positive lung cancer using an anti-pd-1 antibody |
| US20190048085A1 (en) | 2016-02-25 | 2019-02-14 | Cell Medica Switzerland Ag | Modified cells for immunotherapy |
| EP4649966A3 (en) | 2016-12-01 | 2026-02-18 | Regeneron Pharmaceuticals, Inc. | Radiolabeled anti-pd-l1 antibodies for immuno-pet imaging |
| MA47604A (fr) * | 2017-02-21 | 2020-01-01 | Regeneron Pharma | Anticorps anti-pd-1 pour le traitement du cancer du poumon |
| US11603407B2 (en) | 2017-04-06 | 2023-03-14 | Regeneron Pharmaceuticals, Inc. | Stable antibody formulation |
| AU2023356866A1 (en) * | 2022-10-03 | 2025-04-17 | Regeneron Pharmaceuticals, Inc. | Methods of treating cancer with bispecific egfr x cd28 antibodies alone or in combination with anti-pd-1 antibodies |
-
2018
- 2018-02-20 MA MA047604A patent/MA47604A/fr unknown
- 2018-02-20 AU AU2018225102A patent/AU2018225102B2/en active Active
- 2018-02-20 KR KR1020197027687A patent/KR102628557B1/ko active Active
- 2018-02-20 JP JP2019545324A patent/JP7324710B2/ja active Active
- 2018-02-20 CN CN201880026252.8A patent/CN110536905B/zh active Active
- 2018-02-20 US US16/486,688 patent/US11292842B2/en active Active
- 2018-02-20 CN CN202311425489.2A patent/CN117442719A/zh active Pending
- 2018-02-20 EP EP18711195.0A patent/EP3585812A1/en active Pending
- 2018-02-20 IL IL321717A patent/IL321717A/en unknown
- 2018-02-20 WO PCT/US2018/018747 patent/WO2018156494A1/en not_active Ceased
- 2018-02-20 IL IL268479A patent/IL268479B2/en unknown
- 2018-02-20 CA CA3054289A patent/CA3054289A1/en active Pending
- 2018-02-20 MX MX2019009772A patent/MX2019009772A/es unknown
- 2018-02-20 KR KR1020247001790A patent/KR20240011262A/ko active Pending
- 2018-02-20 IL IL308805A patent/IL308805B2/en unknown
-
2019
- 2019-07-31 ZA ZA2019/05051A patent/ZA201905051B/en unknown
- 2019-08-15 MX MX2024000780A patent/MX2024000780A/es unknown
-
2022
- 2022-02-28 US US17/652,709 patent/US11926668B2/en active Active
- 2022-03-11 JP JP2022037781A patent/JP7384949B2/ja active Active
-
2023
- 2023-11-08 JP JP2023190525A patent/JP7656012B2/ja active Active
-
2024
- 2024-01-29 US US18/425,027 patent/US20240209090A1/en active Pending
-
2025
- 2025-02-13 AU AU2025201018A patent/AU2025201018A1/en active Pending
- 2025-03-19 JP JP2025044340A patent/JP2025098103A/ja active Pending
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