JP2021528368A5 - - Google Patents
Info
- Publication number
- JP2021528368A5 JP2021528368A5 JP2020562120A JP2020562120A JP2021528368A5 JP 2021528368 A5 JP2021528368 A5 JP 2021528368A5 JP 2020562120 A JP2020562120 A JP 2020562120A JP 2020562120 A JP2020562120 A JP 2020562120A JP 2021528368 A5 JP2021528368 A5 JP 2021528368A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- alkoxy
- heterocyclyl
- heteroaryl
- sulfo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024022691A JP2024056937A (ja) | 2018-05-10 | 2024-02-19 | Ｒａｓ腫瘍性タンパク質の阻害剤、その作製方法及びその使用方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862669926P | 2018-05-10 | 2018-05-10 | |
| US62/669,926 | 2018-05-10 | ||
| PCT/US2019/031885 WO2019217933A1 (en) | 2018-05-10 | 2019-05-10 | Inhibitors of the ras oncoprotein, methods of making and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024022691A Division JP2024056937A (ja) | 2018-05-10 | 2024-02-19 | Ｒａｓ腫瘍性タンパク質の阻害剤、その作製方法及びその使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021528368A JP2021528368A (ja) | 2021-10-21 |
| JP2021528368A5 true JP2021528368A5 (OSRAM) | 2022-05-17 |
Family
ID=68467113
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020562120A Pending JP2021528368A (ja) | 2018-05-10 | 2019-05-10 | Ｒａｓ腫瘍性タンパク質の阻害剤、その作製方法及びその使用方法 |
| JP2024022691A Pending JP2024056937A (ja) | 2018-05-10 | 2024-02-19 | Ｒａｓ腫瘍性タンパク質の阻害剤、その作製方法及びその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024022691A Pending JP2024056937A (ja) | 2018-05-10 | 2024-02-19 | Ｒａｓ腫瘍性タンパク質の阻害剤、その作製方法及びその使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US12582660B2 (OSRAM) |
| EP (1) | EP3790541B1 (OSRAM) |
| JP (2) | JP2021528368A (OSRAM) |
| KR (1) | KR20210009331A (OSRAM) |
| CN (1) | CN112312901B (OSRAM) |
| AU (1) | AU2019265011B2 (OSRAM) |
| CA (1) | CA3099148A1 (OSRAM) |
| IL (1) | IL278596B2 (OSRAM) |
| MX (1) | MX2020011991A (OSRAM) |
| WO (1) | WO2019217933A1 (OSRAM) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112312901B (zh) | 2018-05-10 | 2024-05-14 | 路易斯维尔大学研究基金会有限公司 | Ras癌蛋白抑制剂及其制备方法和使用方法 |
| KR20230042600A (ko) | 2020-06-18 | 2023-03-28 | 레볼루션 메디슨즈, 인크. | Ras 억제제에 대한 획득된 저항성을 지연, 예방, 및 치료하는 방법 |
| CA3187757A1 (en) | 2020-09-03 | 2022-03-24 | Ethan AHLER | Use of sos1 inhibitors to treat malignancies with shp2 mutations |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60233051A (ja) | 1984-05-04 | 1985-11-19 | Daicel Chem Ind Ltd | ２−クロル−５−ニトロベンゼンスルホンアミドの製造方法 |
| US4944796A (en) * | 1988-11-14 | 1990-07-31 | Ici Americas Inc. | Certain 2-(disubstituted amino) acetanilide herbicides |
| BR9911095A (pt) | 1998-06-09 | 2002-01-15 | Nortran Pharmaceuticals Inc | Compostos de amÈnios quartenário como agentes anti-tussìgenos |
| US20080139534A1 (en) | 2006-12-07 | 2008-06-12 | Xavier University Of Louisiana | Bisbenzamidines and bisbenzamidoximes for the treatment of human African trypanosomiasis |
| WO2009013915A1 (ja) | 2007-07-25 | 2009-01-29 | Renascience Co., Ltd. | プラスミノーゲンアクチベーターインヒビター－１阻害剤 |
| FR2925495B1 (fr) | 2007-12-21 | 2010-09-10 | Pf Medicament | Derives dimeriques d'artemisinine et application en therapie anticancereuse |
| GB0808282D0 (en) * | 2008-05-07 | 2008-06-11 | Medical Res Council | Compounds for use in stabilizing p53 mutants |
| CN101919842A (zh) * | 2009-06-11 | 2010-12-22 | 复旦大学 | 一种苯丙噻吩衍生物在制备抗肿瘤药物中的应用 |
| US8557980B2 (en) | 2010-02-18 | 2013-10-15 | The Board Of Trustees Of The University Of Illinois | Methods for forming protected organoboronic acids |
| AU2011239537A1 (en) * | 2010-04-16 | 2012-11-15 | Curis, Inc. | Treatment of cancers having K-ras mutations |
| KR20120048223A (ko) | 2010-11-05 | 2012-05-15 | 주식회사 이큐스앤자루 | 2-페닐-4-[3-(치환된-설포닐)아닐리노]퀴나졸린 유도체, 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 ｃ형 간염의 예방 또는 치료용 약학적 조성물 |
| GB201020397D0 (en) * | 2010-12-02 | 2011-01-12 | Univ Nottingham | Compounds |
| US9120776B2 (en) * | 2011-09-22 | 2015-09-01 | Takeda Pharmaceutical Company Limited | Condensed heterocyclic compound |
| WO2014037726A1 (en) | 2012-09-06 | 2014-03-13 | Verona Pharma Plc | Liquid pharmaceutical compositions |
| ES2491390B1 (es) * | 2013-02-04 | 2015-06-22 | Universidad Complutense De Madrid | Nuevos inhibidores de la enzima isoprenilcisteina carboximetiltransferasa (icmt) |
| US9499495B2 (en) | 2013-04-12 | 2016-11-22 | Asana Biosciences, Llc | Quinazolines and azaquinazolines as dual inhibitors of RAS/RAF/MEK/ERK and PI3K/AKT/PTEN/mTOR pathways |
| US9181288B2 (en) | 2014-01-16 | 2015-11-10 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
| US20160168108A1 (en) | 2014-12-16 | 2016-06-16 | Adt Pharmaceuticals, Inc. | Method of treating or preventing ras-mediated diseases |
| US10857234B2 (en) | 2016-03-16 | 2020-12-08 | Endocyte Inc. | Carbonic anhydrase IX inhibitor conjugates and uses thereof |
| CN112312901B (zh) | 2018-05-10 | 2024-05-14 | 路易斯维尔大学研究基金会有限公司 | Ras癌蛋白抑制剂及其制备方法和使用方法 |
-
2019
- 2019-05-10 CN CN201980038063.7A patent/CN112312901B/zh active Active
- 2019-05-10 AU AU2019265011A patent/AU2019265011B2/en not_active Expired - Fee Related
- 2019-05-10 IL IL278596A patent/IL278596B2/en unknown
- 2019-05-10 WO PCT/US2019/031885 patent/WO2019217933A1/en not_active Ceased
- 2019-05-10 KR KR1020207035159A patent/KR20210009331A/ko not_active Ceased
- 2019-05-10 MX MX2020011991A patent/MX2020011991A/es unknown
- 2019-05-10 JP JP2020562120A patent/JP2021528368A/ja active Pending
- 2019-05-10 EP EP19800358.4A patent/EP3790541B1/en active Active
- 2019-05-10 CA CA3099148A patent/CA3099148A1/en active Pending
- 2019-05-10 US US17/053,057 patent/US12582660B2/en active Active
-
2024
- 2024-02-19 JP JP2024022691A patent/JP2024056937A/ja active Pending
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