JP2021527083A - ステージｉｉｉ ｎｓｃｌｃの治療及びその治療に伴う病理学的状態の鎮静 - Google Patents

ステージｉｉｉ ｎｓｃｌｃの治療及びその治療に伴う病理学的状態の鎮静 Download PDF

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JP2021527083A
JP2021527083A JP2020568781A JP2020568781A JP2021527083A JP 2021527083 A JP2021527083 A JP 2021527083A JP 2020568781 A JP2020568781 A JP 2020568781A JP 2020568781 A JP2020568781 A JP 2020568781A JP 2021527083 A JP2021527083 A JP 2021527083A
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seq
dose
tgfβ
polypeptide
protein
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JP2021527083A5 (https=
JPWO2019241353A5 (https=
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デュサール，イザベル
グレンガ，イタリア
ヴァグマイスター，ユリア
カーンデルワル，アカシュ
クリステンセン，オラフ
バワブ，サメール エル
ラン，ヤン
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メルク パテント ゲーエムベーハー
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    • A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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  • Peptides Or Proteins (AREA)
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JP2020568781A 2018-06-13 2019-06-12 ステージｉｉｉ ｎｓｃｌｃの治療及びその治療に伴う病理学的状態の鎮静 Pending JP2021527083A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862684385P 2018-06-13 2018-06-13
US62/684,385 2018-06-13
US201962800808P 2019-02-04 2019-02-04
US62/800,808 2019-02-04
US201962855170P 2019-05-31 2019-05-31
US62/855,170 2019-05-31
PCT/US2019/036725 WO2019241353A1 (en) 2018-06-13 2019-06-12 Treatment of stage iii nsclc and mitigation of pathological conditions associated with the treatment

Publications (3)

Publication Number Publication Date
JP2021527083A true JP2021527083A (ja) 2021-10-11
JP2021527083A5 JP2021527083A5 (https=) 2022-08-23
JPWO2019241353A5 JPWO2019241353A5 (https=) 2022-08-23

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JP2020568781A Pending JP2021527083A (ja) 2018-06-13 2019-06-12 ステージｉｉｉ ｎｓｃｌｃの治療及びその治療に伴う病理学的状態の鎮静

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US (1) US20210113656A1 (https=)
EP (1) EP3806842A4 (https=)
JP (1) JP2021527083A (https=)
KR (1) KR20210020098A (https=)
CN (1) CN112566634A (https=)
AU (1) AU2019284765A1 (https=)
BR (1) BR112020025452A2 (https=)
CA (1) CA3103245A1 (https=)
CL (1) CL2020003204A1 (https=)
IL (1) IL279353A (https=)
MX (1) MX2020013535A (https=)
SG (1) SG11202012426WA (https=)
TW (1) TW202011954A (https=)
WO (1) WO2019241353A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202013190YA (en) * 2018-07-02 2021-01-28 Merck Patent Gmbh Combination therapy with targeted tgf-b inhibition for treatment of advanced non-small cell lung cancer
WO2021209458A1 (en) * 2020-04-14 2021-10-21 Ares Trading S.A. Combination treatment of cancer
EP4194468A4 (en) * 2020-08-07 2025-07-16 Bio Thera Solutions Ltd ANTI PD-L1 ANTIBODY AND ITS USE
TW202428254A (zh) * 2022-09-09 2024-07-16 瑞典商阿斯特捷利康公司 用於治療晚期實性瘤之組成物及方法
KR20250155046A (ko) * 2023-03-09 2025-10-29 테릭스 파마슈티컬스 (이노베이션스) 피티와이 엘티디 다작용성 항체

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016140714A1 (en) * 2015-03-05 2016-09-09 The General Hospital Corporation Novel compositions and uses of metformin agents
WO2018029367A1 (en) * 2016-08-12 2018-02-15 Merck Patent Gmbh Combination therapy for cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9676863B2 (en) * 2014-02-10 2017-06-13 Merck Patent Gmbh Targeted TGFβ inhibitors
NZ733854A (en) * 2015-02-26 2022-07-01 Merck Patent Gmbh Pd-1 / pd-l1 inhibitors for the treatment of cancer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016140714A1 (en) * 2015-03-05 2016-09-09 The General Hospital Corporation Novel compositions and uses of metformin agents
WO2018029367A1 (en) * 2016-08-12 2018-02-15 Merck Patent Gmbh Combination therapy for cancer

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ONCOIMMUNOLOGY, vol. 6, no. 10, JPN6023017435, pages 1349589 - 1, ISSN: 0005199517 *
W'WAVES, vol. 19, no. 1, JPN6023017436, 2013, pages 63 - 64, ISSN: 0005199516 *

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Publication number Publication date
CA3103245A1 (en) 2019-12-19
CN112566634A (zh) 2021-03-26
SG11202012426WA (en) 2021-01-28
KR20210020098A (ko) 2021-02-23
US20210113656A1 (en) 2021-04-22
EP3806842A4 (en) 2022-03-16
AU2019284765A1 (en) 2021-01-07
BR112020025452A2 (pt) 2021-03-16
TW202011954A (zh) 2020-04-01
IL279353A (en) 2021-01-31
EP3806842A1 (en) 2021-04-21
CL2020003204A1 (es) 2021-06-18
WO2019241353A1 (en) 2019-12-19
MX2020013535A (es) 2021-02-26

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