JP2021525752A5 - - Google Patents
Info
- Publication number
- JP2021525752A5 JP2021525752A5 JP2020566834A JP2020566834A JP2021525752A5 JP 2021525752 A5 JP2021525752 A5 JP 2021525752A5 JP 2020566834 A JP2020566834 A JP 2020566834A JP 2020566834 A JP2020566834 A JP 2020566834A JP 2021525752 A5 JP2021525752 A5 JP 2021525752A5
- Authority
- JP
- Japan
- Prior art keywords
- present
- activation
- novel heterocyclic
- stat3 protein
- suppresses
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20180062450 | 2018-05-31 | ||
| KR10-2018-0062450 | 2018-05-31 | ||
| PCT/KR2019/006554 WO2019231271A1 (en) | 2018-05-31 | 2019-05-31 | Heterocyclic derivatives and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021525752A JP2021525752A (ja) | 2021-09-27 |
| JP2021525752A5 true JP2021525752A5 (enExample) | 2022-03-31 |
| JP7558066B2 JP7558066B2 (ja) | 2024-09-30 |
Family
ID=68698337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020566834A Active JP7558066B2 (ja) | 2018-05-31 | 2019-05-31 | 複素環誘導体及びその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US12404249B2 (enExample) |
| EP (1) | EP3802495B1 (enExample) |
| JP (1) | JP7558066B2 (enExample) |
| KR (1) | KR102229471B1 (enExample) |
| CN (1) | CN112204010B (enExample) |
| ES (1) | ES3041067T3 (enExample) |
| TW (1) | TWI853814B (enExample) |
| WO (1) | WO2019231271A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110105237B (zh) * | 2019-06-06 | 2021-12-24 | 东北师范大学 | 一种β-偕二氟叠氮化合物及其制备和应用 |
| WO2022187411A1 (en) * | 2021-03-02 | 2022-09-09 | Kumquat Biosciences Inc. | Heterocycles and uses thereof |
| CN113845476B (zh) * | 2021-11-08 | 2024-04-30 | 中国药科大学 | 一种喹诺酮衍生物及其制备方法和用途 |
| CN114315802B (zh) * | 2021-12-14 | 2023-06-16 | 西安医学院 | 一种喹唑啉含氮杂环衍生物及制备方法和用途 |
| CA3246750A1 (en) | 2022-04-20 | 2023-10-26 | Kumquat Biosciences Inc. | MACROCYCLES AND HETEROCYCLES AND THEIR USES |
| EP4296674A1 (en) | 2022-06-20 | 2023-12-27 | Université Toulouse III - Paul Sabatier | Innovative molecules decreasing virulence of mycobacterium for the treatment of tuberculosis |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR960007566A (ko) * | 1994-08-19 | 1996-03-22 | 김정규 | 신규한 퀴놀릴아민 유도체, 그의 제조방법 및 항부정맥제로서의 용도 |
| AU4878601A (en) | 2000-04-20 | 2001-11-07 | Mitsubishi Corporation | Aromatic amide compounds |
| PE20030008A1 (es) * | 2001-06-19 | 2003-01-22 | Bristol Myers Squibb Co | Inhibidores duales de pde 7 y pde 4 |
| WO2005061516A1 (en) * | 2003-12-04 | 2005-07-07 | Smithkline Beecham Corporation | Novel chemical compounds |
| GB0420719D0 (en) * | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
| US20060074105A1 (en) * | 2004-09-20 | 2006-04-06 | Serenex, Inc. | Substituted quinoline and quinazoline inhibitors of quinone reductase 2 |
| US7932257B2 (en) | 2005-07-22 | 2011-04-26 | Sunesis Pharmaceuticals, Inc. | Substituted pyrazolo[4,3-d]pyrimidines as aurora kinase inhibitors |
| US20090170847A1 (en) * | 2006-01-23 | 2009-07-02 | Seung Chul Lee | Imidazopyridine Derivatives Inhibiting Protein Kinase Activity, Method for the Preparation Thereof and Pharmaceutical Composition Containing Same |
| US20090004185A1 (en) * | 2007-01-11 | 2009-01-01 | Wyeth | Amino-substituted quinazoline derivatives as inhibitors of beta-catenin/tcf-4 pathway and cancer treatment agents |
| EP2014663A1 (de) * | 2007-07-12 | 2009-01-14 | Bayer Schering Pharma AG | Thienopyrimidylamine als Modulatoren des EP2-Rezeptors |
| DE102007032739A1 (de) | 2007-07-13 | 2009-01-15 | Merck Patent Gmbh | Chinazolinamidderivate |
| AU2009219376B2 (en) * | 2008-02-28 | 2014-09-25 | Merck Patent Gmbh | Protein kinase inhibitors and use thereof |
| US8466290B2 (en) | 2008-07-10 | 2013-06-18 | Pharma Ip General Incorporated Association | STAT3 inhibitor containing quinolinecarboxamide derivative as active ingredient |
| JP5507567B2 (ja) | 2008-09-26 | 2014-05-28 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｃｃｒ１受容体拮抗薬としてのアザインダゾール化合物 |
| EP2331530B8 (en) * | 2008-09-26 | 2013-12-25 | National Health Research Institutes | Fused multicyclic compounds as protein kinase inhibitors |
| BRPI1008325A2 (pt) * | 2009-02-11 | 2020-08-25 | Merck Patent Gmbh | carboxamidas azaeterocíclicas de amino |
| WO2012079079A1 (en) * | 2010-12-10 | 2012-06-14 | President And Fellows Of Harvard College | Production of induced pluripotent stem cells |
| WO2014145512A2 (en) * | 2013-03-15 | 2014-09-18 | President And Fellows Of Harvard College | Potent small molecule inhibitors of autophagy, and methods of use thereof |
| KR20200047627A (ko) * | 2017-08-31 | 2020-05-07 | 애브비 인코포레이티드 | 엑토뉴클레오티드 피로포스파타아제-포스포디에스테라아제 1(enpp-1) 저해제 및 그의 용도 |
-
2019
- 2019-05-30 TW TW108118755A patent/TWI853814B/zh active
- 2019-05-31 WO PCT/KR2019/006554 patent/WO2019231271A1/en not_active Ceased
- 2019-05-31 KR KR1020190064288A patent/KR102229471B1/ko active Active
- 2019-05-31 US US17/058,209 patent/US12404249B2/en active Active
- 2019-05-31 ES ES19812552T patent/ES3041067T3/es active Active
- 2019-05-31 EP EP19812552.8A patent/EP3802495B1/en active Active
- 2019-05-31 CN CN201980035635.6A patent/CN112204010B/zh active Active
- 2019-05-31 JP JP2020566834A patent/JP7558066B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1124084T1 (el) | Αμιδο-υποκατεστημενα παραγωγα πυριδινυλοτριαζολης και χρησεις αυτων | |
| JOP20210001B1 (ar) | مشتقات 3-(5- هيدروكسي -1- أوكسو أيزو إندولين -2- يل) بيبريدين -2، 6- دايون واستخدامها لمعالجة أمراض مرتبطة ببروتين ذات أصبع الزنك من عائلة (ikaros 2 (ikzf2 | |
| PH12020551205A1 (en) | Fap inhibitors | |
| GEAP202215671A (en) | Microbiocidal thiazole derivatives | |
| IL280358A (en) | Novel autotac chimeric compound, and composition for preventing, ameliorating or treating diseases through targeted protein degradation comprosing the same | |
| EA201791261A1 (ru) | 1,3-тиазол-2-ил замещенные бензамиды | |
| MX2019012445A (es) | Anticuerpos anti-peptido beta amiloide n3pglu y usos de los mismos. | |
| CL2004001011A1 (es) | Compuestos azabiciclicos derivados de n-arilsulfonilpiperidinas; inhibidores de la deposicion de la proteina beta amiloide; composicion farmaceutica; y su uso para el tratamiento del alzheimer y enfermedades neurodegenerativas. | |
| EA202191991A1 (ru) | Новые производные гетеротрициклического соединения и их применение | |
| EA201792421A1 (ru) | Амидозамещенные производные циклогексана | |
| EA201691242A1 (ru) | Фармацевтические композиции, содержащие azd9291 | |
| EA202190356A1 (ru) | Композиции и способы лечения расстройств, ослабляемых активацией мускариновых рецепторов | |
| MX379558B (es) | Nueva forma cristalina de n-[5-(3,5-difluoro-bencilo)-1h-indazol-3-il]-4-(4-metilo-piperazina-1-il)-2-(tetrahidro-pirano-4-ilamino)-benzamida. | |
| BR112018006866A2 (pt) | compostos agonistas de ppar, composições farmacêuticas e métodos de uso dos mesmos | |
| ME01456B (me) | Fumaratna so (alfa s, beta r)-6-bromo-alfa-[2-(dimetilamino)etil]-2-metoksi-alfa-1-naftalenil-beta-fenil-3-kinolinetanola | |
| SA521422467B1 (ar) | مركبات هالو-آلِّيلامين واستخدامها | |
| JP2018186833A5 (enExample) | ||
| JOP20210034A1 (ar) | مركبات عطرية غير متجانسة كمثبطات Vanin | |
| EA202191478A1 (ru) | Гетероароматические соединения в качестве ингибиторов ванина | |
| EA202192925A1 (ru) | Твердые формы ингибитора glyt1 | |
| SG11202011427XA (en) | Fish protein hydrolysate powder and a composition comprising said powder for use as a medicament | |
| SG10201805646WA (en) | Angiopoietin-like 4 antibodies and methods of use | |
| BR112021011368A2 (pt) | Cocristal de cetoprofeno, composições compreendendo o mesmo, processo para a sua produção e usos dos mesmos | |
| HUE066894T2 (hu) | Triszamid vegyületek és azokat tartalmazó készítmények | |
| EP3880671A4 (en) | NOVEL COMPOUND AS A PROTEIN KINAS INHIBITOR AND PHARMACEUTICAL COMPOSITION THEREOF |