JP2021524844A5 - - Google Patents
Info
- Publication number
- JP2021524844A5 JP2021524844A5 JP2020564095A JP2020564095A JP2021524844A5 JP 2021524844 A5 JP2021524844 A5 JP 2021524844A5 JP 2020564095 A JP2020564095 A JP 2020564095A JP 2020564095 A JP2020564095 A JP 2020564095A JP 2021524844 A5 JP2021524844 A5 JP 2021524844A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- human
- alkylthioalkyl
- thioalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024003447A JP7736825B2 (ja) | 2018-05-15 | 2024-01-12 | 腫瘍転移および腫瘍発生の予防および治療のための製剤および方法 |
| JP2025142520A JP2026000929A (ja) | 2018-05-15 | 2025-08-28 | 腫瘍転移および腫瘍発生の予防および治療のための製剤および方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862671964P | 2018-05-15 | 2018-05-15 | |
| US62/671,964 | 2018-05-15 | ||
| PCT/US2019/032461 WO2019222380A1 (en) | 2018-05-15 | 2019-05-15 | Formulations and methods for the prevention and treatment of tumor metastasis and tumorigenesis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024003447A Division JP7736825B2 (ja) | 2018-05-15 | 2024-01-12 | 腫瘍転移および腫瘍発生の予防および治療のための製剤および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021524844A JP2021524844A (ja) | 2021-09-16 |
| JP2021524844A5 true JP2021524844A5 (enExample) | 2022-05-23 |
| JP7421499B2 JP7421499B2 (ja) | 2024-01-24 |
Family
ID=66691010
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020564095A Active JP7421499B2 (ja) | 2018-05-15 | 2019-05-15 | 腫瘍転移および腫瘍発生の予防および治療のための製剤および方法 |
| JP2024003447A Active JP7736825B2 (ja) | 2018-05-15 | 2024-01-12 | 腫瘍転移および腫瘍発生の予防および治療のための製剤および方法 |
| JP2025142520A Pending JP2026000929A (ja) | 2018-05-15 | 2025-08-28 | 腫瘍転移および腫瘍発生の予防および治療のための製剤および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024003447A Active JP7736825B2 (ja) | 2018-05-15 | 2024-01-12 | 腫瘍転移および腫瘍発生の予防および治療のための製剤および方法 |
| JP2025142520A Pending JP2026000929A (ja) | 2018-05-15 | 2025-08-28 | 腫瘍転移および腫瘍発生の予防および治療のための製剤および方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20210186972A1 (enExample) |
| EP (2) | EP4721727A3 (enExample) |
| JP (3) | JP7421499B2 (enExample) |
| AU (2) | AU2019271208B2 (enExample) |
| CA (1) | CA3100211A1 (enExample) |
| ES (1) | ES3061722T3 (enExample) |
| WO (1) | WO2019222380A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2019004950A (es) | 2016-10-28 | 2019-09-26 | Icahn School Med Mount Sinai | Composiciones y metodos para tratar el cancer mediado por el potenciador del homologo zeste 2. |
| CA3045037A1 (en) | 2016-12-08 | 2018-06-14 | Icahn School Of Medicine At Mount Sinai | Compositions and methods for treating cdk4/6-mediated cancer |
| JP2021515013A (ja) | 2018-03-06 | 2021-06-17 | アイカーン スクール オブ メディスン アット マウント シナイ | セリンスレオニンキナーゼ（ａｋｔ）分解／破壊化合物および使用方法 |
| JP2021527666A (ja) | 2018-06-21 | 2021-10-14 | アイカーン スクール オブ メディスン アット マウント シナイ | Ｗｄ４０反復ドメインタンパク質５（ｗｄｒ５）分解／破壊化合物および使用の方法 |
| WO2020010204A1 (en) | 2018-07-05 | 2020-01-09 | Icahn School Of Medicine At Mount Sinai | Protein tyrosine kinase 6 (ptk6) degradation / disruption compounds and methods of use |
| CN114423463B (zh) | 2019-05-06 | 2025-09-26 | 西奈山伊坎医学院 | 作为hpk1的降解剂的异双功能化合物 |
| US12103924B2 (en) | 2020-06-01 | 2024-10-01 | Icahn School Of Medicine At Mount Sinai | Mitogen-activated protein kinase kinase (MEK) degradation compounds and methods of use |
| WO2022159650A1 (en) * | 2021-01-22 | 2022-07-28 | Icahn School Of Medicine At Mount Sinai | HETEROBIFUNCTIONAL COMPOUNDS AS DEGRADERS OF eEF1A2 |
| US20260028342A1 (en) * | 2022-07-29 | 2026-01-29 | The University Of North Carolina At Chapel Hill | Enhancing antimetastasis activity using targeted protein degradation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030236236A1 (en) * | 1999-06-30 | 2003-12-25 | Feng-Jing Chen | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs |
| WO2009121069A2 (en) * | 2008-03-28 | 2009-10-01 | University Of Massachusetts | Compositions and methods for the preparation of nanoemulsions |
| CN102026667B (zh) * | 2008-04-18 | 2014-06-25 | 安吉奥开米公司 | 紫杉醇、紫杉醇类似物或紫杉醇结合物的药物组合物及相关制备方法和用途 |
| US9663521B2 (en) * | 2011-12-16 | 2017-05-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Compounds and methods for the prevention and treatment of tumor metastasis and tumorigenesis |
| US9877966B1 (en) * | 2015-08-10 | 2018-01-30 | Eugene J. Oliva | Combination therapy for the inhibition of metastasis and tumorigenesis |
| TWI715636B (zh) * | 2015-09-30 | 2021-01-11 | 香港商慧源香港創新有限公司 | 口服紫杉烷組合物及方法 |
| US11241436B2 (en) * | 2017-01-25 | 2022-02-08 | Northwestern University | Autophagy inducers for treatment of CNS conditions |
-
2019
- 2019-05-15 CA CA3100211A patent/CA3100211A1/en active Pending
- 2019-05-15 ES ES19728226T patent/ES3061722T3/es active Active
- 2019-05-15 US US17/055,256 patent/US20210186972A1/en not_active Abandoned
- 2019-05-15 EP EP25214810.1A patent/EP4721727A3/en active Pending
- 2019-05-15 AU AU2019271208A patent/AU2019271208B2/en active Active
- 2019-05-15 WO PCT/US2019/032461 patent/WO2019222380A1/en not_active Ceased
- 2019-05-15 EP EP19728226.2A patent/EP3793523B8/en active Active
- 2019-05-15 JP JP2020564095A patent/JP7421499B2/ja active Active
-
2024
- 2024-01-12 JP JP2024003447A patent/JP7736825B2/ja active Active
- 2024-06-06 US US18/735,506 patent/US20240316056A1/en active Pending
-
2025
- 2025-05-12 AU AU2025203402A patent/AU2025203402A1/en active Pending
- 2025-08-28 JP JP2025142520A patent/JP2026000929A/ja active Pending
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