JP2021523733A - 動物病原体由来ポリペプチドおよびその遺伝子工学的利用 - Google Patents
動物病原体由来ポリペプチドおよびその遺伝子工学的利用 Download PDFInfo
- Publication number
- JP2021523733A JP2021523733A JP2021506378A JP2021506378A JP2021523733A JP 2021523733 A JP2021523733 A JP 2021523733A JP 2021506378 A JP2021506378 A JP 2021506378A JP 2021506378 A JP2021506378 A JP 2021506378A JP 2021523733 A JP2021523733 A JP 2021523733A
- Authority
- JP
- Japan
- Prior art keywords
- gene
- seq
- sequence
- amino acid
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024198757A JP2025037883A (ja) | 2018-04-18 | 2024-11-14 | 動物病原体由来ポリペプチドおよびその遺伝子工学的利用 |
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862659656P | 2018-04-18 | 2018-04-18 | |
| US62/659,656 | 2018-04-18 | ||
| US201862690905P | 2018-06-27 | 2018-06-27 | |
| US62/690,905 | 2018-06-27 | ||
| US201862716223P | 2018-08-08 | 2018-08-08 | |
| US62/716,223 | 2018-08-08 | ||
| US201862738825P | 2018-09-28 | 2018-09-28 | |
| US62/738,825 | 2018-09-28 | ||
| US201962819237P | 2019-03-15 | 2019-03-15 | |
| US62/819,237 | 2019-03-15 | ||
| PCT/US2019/028174 WO2019204643A2 (en) | 2018-04-18 | 2019-04-18 | Animal pathogen-derived polypeptides and uses thereof for genetic engineering |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024198757A Division JP2025037883A (ja) | 2018-04-18 | 2024-11-14 | 動物病原体由来ポリペプチドおよびその遺伝子工学的利用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021523733A true JP2021523733A (ja) | 2021-09-09 |
| JPWO2019204643A5 JPWO2019204643A5 (https=) | 2022-04-20 |
| JP2021523733A5 JP2021523733A5 (https=) | 2022-04-20 |
Family
ID=68240638
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021506378A Pending JP2021523733A (ja) | 2018-04-18 | 2019-04-18 | 動物病原体由来ポリペプチドおよびその遺伝子工学的利用 |
| JP2024198757A Pending JP2025037883A (ja) | 2018-04-18 | 2024-11-14 | 動物病原体由来ポリペプチドおよびその遺伝子工学的利用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024198757A Pending JP2025037883A (ja) | 2018-04-18 | 2024-11-14 | 動物病原体由来ポリペプチドおよびその遺伝子工学的利用 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US12312383B2 (https=) |
| EP (1) | EP3781193A4 (https=) |
| JP (2) | JP2021523733A (https=) |
| AU (1) | AU2019256517B2 (https=) |
| CA (1) | CA3097648A1 (https=) |
| WO (1) | WO2019204643A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4010004A4 (en) * | 2019-08-07 | 2023-09-13 | Altius Institute For Biomedical Sciences | Compositions and methods for modulation of gene expression |
| JP7507242B2 (ja) * | 2020-08-25 | 2024-06-27 | 中興通訊股▲ふん▼有限公司 | 無線ネットワーク一時識別子に関連する方法および装置 |
| AU2021392032A1 (en) | 2020-12-03 | 2023-06-22 | Century Therapeutics, Inc. | Genetically engineered cells and uses thereof |
| US11661459B2 (en) | 2020-12-03 | 2023-05-30 | Century Therapeutics, Inc. | Artificial cell death polypeptide for chimeric antigen receptor and uses thereof |
| AR124414A1 (es) | 2020-12-18 | 2023-03-22 | Century Therapeutics Inc | Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable |
| WO2025034754A2 (en) * | 2023-08-08 | 2025-02-13 | Altius Institute For Biomedical Sciences | Nucleic acid binding domains and methods of use thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014018601A2 (en) * | 2012-07-24 | 2014-01-30 | Cellectis | New modular base-specific nucleic acid binding domains from burkholderia rhizoxinica proteins |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60140474D1 (de) * | 2000-09-08 | 2009-12-24 | Univ Zuerich | Sammlung von proteinen mit sich wiederholenden sequenzen (repeat proteins), die repetitive sequenzmodule enthalten |
| EP2206723A1 (en) | 2009-01-12 | 2010-07-14 | Bonas, Ulla | Modular DNA-binding domains |
| US20110239315A1 (en) * | 2009-01-12 | 2011-09-29 | Ulla Bonas | Modular dna-binding domains and methods of use |
| JP5866283B2 (ja) | 2009-07-28 | 2016-02-17 | サンガモ バイオサイエンシーズ, インコーポレイテッド | トリヌクレオチド反復疾患を治療するための方法および組成物 |
| HUE041436T2 (hu) | 2009-12-10 | 2019-05-28 | Univ Minnesota | Tal-effektor-közvetített DNS-módosítás |
| EP2534163B1 (en) | 2010-02-09 | 2015-11-04 | Sangamo BioSciences, Inc. | Targeted genomic modification with partially single-stranded donor molecules |
| JP6208580B2 (ja) | 2010-05-17 | 2017-10-04 | サンガモ セラピューティクス, インコーポレイテッド | 新規のdna結合タンパク質及びその使用 |
| US9499592B2 (en) | 2011-01-26 | 2016-11-22 | President And Fellows Of Harvard College | Transcription activator-like effectors |
| WO2012168304A1 (en) | 2011-06-07 | 2012-12-13 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Protein having nuclease activity, fusion proteins and uses thereof |
| CA2841710C (en) | 2011-07-15 | 2021-03-16 | The General Hospital Corporation | Methods of transcription activator like effector assembly |
| WO2013015220A1 (ja) | 2011-07-22 | 2013-01-31 | 株式会社東芝 | X線診断装置及び制御プログラム |
| AU2012312260B2 (en) | 2011-09-21 | 2017-08-31 | Sangamo Therapeutics, Inc. | Methods and compositions for regulation of transgene expression |
| AU2012340213B2 (en) | 2011-11-16 | 2017-12-07 | Sangamo Therapeutics, Inc. | Modified DNA-binding proteins and uses thereof |
| US8450107B1 (en) | 2011-11-30 | 2013-05-28 | The Broad Institute Inc. | Nucleotide-specific recognition sequences for designer TAL effectors |
| DK3141259T3 (da) | 2012-03-15 | 2019-09-30 | Cellectis | Repeat-variable direster til targeting af nukleotider |
| WO2013152220A2 (en) * | 2012-04-04 | 2013-10-10 | Life Technologies Corporation | Tal-effector assembly platform, customized services, kits and assays |
| DK2893022T3 (da) | 2012-09-04 | 2020-07-27 | Scripps Research Inst | Kimæriske polypeptider med målrettet bindingsspecificitet |
| US9181535B2 (en) | 2012-09-24 | 2015-11-10 | The Chinese University Of Hong Kong | Transcription activator-like effector nucleases (TALENs) |
| WO2014071219A1 (en) | 2012-11-01 | 2014-05-08 | Factor Bioscience Inc. | Methods and products for expressing proteins in cells |
| ES2778033T3 (es) | 2012-11-16 | 2020-08-07 | Poseida Therapeutics Inc | Enzimas específicas de sitio y métodos de uso |
| US9708589B2 (en) | 2012-12-18 | 2017-07-18 | Monsanto Technology Llc | Compositions and methods for custom site-specific DNA recombinases |
| US20150376585A1 (en) | 2013-02-01 | 2015-12-31 | Cellectis | Tevi chimeric endonuclease and their preferential cleavage sites |
| KR102251168B1 (ko) | 2013-10-25 | 2021-05-13 | 셀렉티스 | 고 반복 모티프를 포함하는 dna 서열에 대한 효율적이고 특이적인 표적화를 위한 희소-절단 엔도뉴클레아제의 설계 |
| US9850497B2 (en) | 2013-11-04 | 2017-12-26 | Regents Of The University Of Minnesota | Gene targeting methods and tools |
| WO2015164748A1 (en) | 2014-04-24 | 2015-10-29 | Sangamo Biosciences, Inc. | Engineered transcription activator like effector (tale) proteins |
| US10612011B2 (en) | 2015-07-30 | 2020-04-07 | President And Fellows Of Harvard College | Evolution of TALENs |
| US11353400B2 (en) | 2016-07-19 | 2022-06-07 | Altius Institute For Biomedical Sciences | Methods for fluorescence imaging microscopy and Nano-FISH |
| CN110312799A (zh) | 2016-08-17 | 2019-10-08 | 博德研究所 | 新型crispr酶和系统 |
| SG10201913948PA (en) | 2016-08-24 | 2020-03-30 | Sangamo Therapeutics Inc | Engineered target specific nucleases |
| AU2018221730B2 (en) | 2017-02-15 | 2024-06-20 | Novo Nordisk A/S | Donor repair templates multiplex genome editing |
| US12264181B2 (en) | 2018-06-27 | 2025-04-01 | Altius Institute For Biomedical Sciences | Nucleic acid binding domains and methods of use thereof |
| WO2020006131A2 (en) | 2018-06-27 | 2020-01-02 | Altius Institute For Biomedical Sciences | Nucleases for genome editing |
-
2019
- 2019-04-18 JP JP2021506378A patent/JP2021523733A/ja active Pending
- 2019-04-18 AU AU2019256517A patent/AU2019256517B2/en active Active
- 2019-04-18 WO PCT/US2019/028174 patent/WO2019204643A2/en not_active Ceased
- 2019-04-18 EP EP19787669.1A patent/EP3781193A4/en active Pending
- 2019-04-18 CA CA3097648A patent/CA3097648A1/en active Pending
- 2019-04-18 US US17/047,373 patent/US12312383B2/en active Active
-
2024
- 2024-11-14 JP JP2024198757A patent/JP2025037883A/ja active Pending
-
2025
- 2025-04-29 US US19/193,869 patent/US20250361275A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014018601A2 (en) * | 2012-07-24 | 2014-01-30 | Cellectis | New modular base-specific nucleic acid binding domains from burkholderia rhizoxinica proteins |
Non-Patent Citations (3)
| Title |
|---|
| "DE SubName: Full=Avirulence protein AvrBs3 {ECO:0000313|EMBL:KTD30443.1}", DATABASE UNIPROT [ONLINE],AC A0A0W0WDL4, JPN6023012099, 28 March 2018 (2018-03-28), ISSN: 0005370048 * |
| "DE SubName: Full=IcmE/DotG protein {ECO:0000313|EMBL:KTD51021.1}", DATABASE UNIPROT [ONLINE],AC A0A0W0Y1V4, JPN6023012098, 28 March 2018 (2018-03-28), ISSN: 0005370047 * |
| "DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OGV28801.1}", DATABASE UNIPROT [ONLINE],AC A0A1G0X562, JPN6023012100, 7 June 2017 (2017-06-07), ISSN: 0005370049 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US12312383B2 (en) | 2025-05-27 |
| EP3781193A4 (en) | 2022-01-26 |
| WO2019204643A3 (en) | 2019-11-28 |
| AU2019256517B2 (en) | 2025-05-29 |
| US20250361275A1 (en) | 2025-11-27 |
| CA3097648A1 (en) | 2019-10-24 |
| AU2019256517A1 (en) | 2020-11-12 |
| US20210115093A1 (en) | 2021-04-22 |
| EP3781193A2 (en) | 2021-02-24 |
| WO2019204643A2 (en) | 2019-10-24 |
| JP2025037883A (ja) | 2025-03-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021523733A (ja) | 動物病原体由来ポリペプチドおよびその遺伝子工学的利用 | |
| AU2021200127B2 (en) | Delivery of negatively charged proteins using cationic lipids | |
| US20250289853A1 (en) | Nucleic acid binding domains and methods of use thereof | |
| US10676735B2 (en) | High-throughput screening of regulatory element function with epigenome editing technologies | |
| JP6905755B2 (ja) | Rnaガイド型エンドヌクレアーゼを使用してゲノム工学における特異性を改善する組成物および方法 | |
| ES2808687T3 (es) | Métodos y composiciones para escisión dirigida y recombinación | |
| CN111989113B (zh) | 用于治疗癌症的包含向导rna和核酸内切酶作活性成分的药物组合物 | |
| JP2021164463A (ja) | エピゲノム編集のための組成物および方法 | |
| EP4434997A2 (en) | Delivery of negatively charged proteins using cationic lipids | |
| US12275935B2 (en) | Gapped and tunable repeat units for use in genome editing and gene regulation compositions | |
| US11439692B2 (en) | Method of treating diseases associated with MYD88 pathways using CRISPR-GNDM system | |
| US12209259B2 (en) | Nucleases for genome editing | |
| WO2018227755A1 (zh) | 用于特异性修复人hbb基因突变的碱基编辑系统、方法、试剂盒及其应用 | |
| EP3884063B1 (en) | Compositions and methods for detection of cleavage of genomic dna by a nuclease | |
| WO2025034754A2 (en) | Nucleic acid binding domains and methods of use thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20220412 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20220412 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20230404 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20230630 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20231003 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20231107 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20240118 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20240502 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20240716 |