JP2021522775A5 - - Google Patents

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Publication number
JP2021522775A5
JP2021522775A5 JP2019565168A JP2019565168A JP2021522775A5 JP 2021522775 A5 JP2021522775 A5 JP 2021522775A5 JP 2019565168 A JP2019565168 A JP 2019565168A JP 2019565168 A JP2019565168 A JP 2019565168A JP 2021522775 A5 JP2021522775 A5 JP 2021522775A5
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JP
Japan
Prior art keywords
aav
nucleic acid
serotype
derived
virions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019565168A
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English (en)
Japanese (ja)
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JP2021522775A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/044632 external-priority patent/WO2019216932A1/en
Publication of JP2021522775A publication Critical patent/JP2021522775A/ja
Publication of JP2021522775A5 publication Critical patent/JP2021522775A5/ja
Priority to JP2023125955A priority Critical patent/JP2023154428A/ja
Pending legal-status Critical Current

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JP2019565168A 2018-05-07 2018-07-31 合理的なポリプロイド性アデノ随伴ウイルスベクターならびにその製造法および使用法 Pending JP2021522775A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023125955A JP2023154428A (ja) 2018-05-07 2023-08-02 合理的なポリプロイド性アデノ随伴ウイルスベクターならびにその製造法および使用法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862668056P 2018-05-07 2018-05-07
US62/668,056 2018-05-07
US201862678675P 2018-05-31 2018-05-31
US62/678,675 2018-05-31
PCT/US2018/044632 WO2019216932A1 (en) 2018-05-07 2018-07-31 Rational polyploid adeno-associated virus vectors and methods of making and using the same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023125955A Division JP2023154428A (ja) 2018-05-07 2023-08-02 合理的なポリプロイド性アデノ随伴ウイルスベクターならびにその製造法および使用法

Publications (2)

Publication Number Publication Date
JP2021522775A JP2021522775A (ja) 2021-09-02
JP2021522775A5 true JP2021522775A5 (https=) 2021-10-14

Family

ID=68468205

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019565168A Pending JP2021522775A (ja) 2018-05-07 2018-07-31 合理的なポリプロイド性アデノ随伴ウイルスベクターならびにその製造法および使用法
JP2023125955A Pending JP2023154428A (ja) 2018-05-07 2023-08-02 合理的なポリプロイド性アデノ随伴ウイルスベクターならびにその製造法および使用法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023125955A Pending JP2023154428A (ja) 2018-05-07 2023-08-02 合理的なポリプロイド性アデノ随伴ウイルスベクターならびにその製造法および使用法

Country Status (6)

Country Link
EP (1) EP3596203A4 (https=)
JP (2) JP2021522775A (https=)
CN (2) CN117535247A (https=)
AU (1) AU2018422759B2 (https=)
IL (1) IL269184B2 (https=)
WO (1) WO2019216932A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110684800B (zh) * 2018-11-02 2020-11-03 深圳益世康宁生物科技有限公司 一种携带肿瘤-睾丸抗原10基因的重组腺相关病毒载体及其应用价值
AU2021205250A1 (en) * 2020-01-07 2022-08-18 The University Of North Carolina At Chapel Hill Synthetic adeno-associated virus inverted terminal repeats and methods of their use as promoters
TWI900553B (zh) * 2020-05-13 2025-10-11 美商航海家醫療公司 Aav蛋白殼之趨性重定向
WO2022221529A1 (en) * 2021-04-16 2022-10-20 Asklepios Biopharmaceutical, Inc. Rational polyploid aav virions that cross the blood brain barrier and elicit reduced humoral response
AU2022286647A1 (en) * 2021-06-02 2023-11-30 Uniqure Biopharma B.V. Insect cell production of parvoviral vectors with modified capsid proteins

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1496944T1 (sl) * 2002-05-01 2009-02-28 Univ Florida Izboljšani sistemi ekspresije RAAV za genetsko modifikacijo specifičnih kapsidnih proteinov
CA2500523A1 (en) * 2003-05-01 2004-11-18 University Of Florida Research Foundation, Inc. Vp2-modified raav vector compositions and uses therefor
WO2005021033A2 (en) * 2003-09-02 2005-03-10 Glaxosmithkline Biologicals S.A. Vaccine
ES2535877T3 (es) * 2006-06-19 2015-05-18 Asklepios Biopharmaceutical, Inc. Genes de Factor VIII y Factor IX modificados y vectores para la terapia génica
US10415056B2 (en) * 2010-11-10 2019-09-17 Fred Hutchinson Cancer Research Center Compositions and methods for generating adeno-associated viral vectors with undetectable capsid gene contamination
EP2675484B1 (en) * 2011-02-14 2018-05-30 The Children's Hospital of Philadelphia Improved aav8 vector with enhanced functional activity and methods of use thereof
GB201103062D0 (en) * 2011-02-22 2011-04-06 Isis Innovation Method
IL297919A (en) * 2013-07-22 2023-01-01 Childrens Hospital Philadelphia Variant aav and compositions, methods and uses for gene transfer to cells, organs and tissues
WO2018109207A1 (en) * 2016-12-16 2018-06-21 Uniqure Ip B.V. Immunoadsorption
NZ756587A (en) * 2017-03-15 2025-12-19 Univ North Carolina Chapel Hill Polyploid adeno-associated virus vectors and methods of making and using the same

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