JP2021514364A - 白斑を処置するための方法及び組成物 - Google Patents
白斑を処置するための方法及び組成物 Download PDFInfo
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- melanocytes
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Abstract
Description
Claims (5)
- CXCR3Bのアンタゴニストの治療的有効量を被験者に投与する工程を含む、それを必要とする被験者において白斑を処置するための方法。
- CXCR3Bのアンタゴニストが有機小分子である、請求項1記載の方法。
- CXCR3Bのアンタゴニストが抗体である、請求項1記載の方法。
- CXCR3B発現のアンタゴニストがsiRNAである、請求項1記載の方法。
- i)試験化合物を提供すること、及びii)CXCR3Bの活性を阻害する前記試験化合物の能力を決定することを含む、ミトコンドリア遺伝性疾患の処置のために適切な薬物をスクリーニングする方法。
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PCT/EP2019/053767 WO2019158675A1 (en) | 2018-02-16 | 2019-02-15 | Methods and compositions for treating vitiligo |
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CN114507729A (zh) * | 2022-03-16 | 2022-05-17 | 中南大学湘雅二医院 | Ocln基因或其蛋白作为靶点在制备白癜风诊断试剂盒或药物中的应用 |
Citations (2)
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WO2013109974A2 (en) * | 2012-01-20 | 2013-07-25 | Genzyme Corporation | Anti-cxcr3 antibodies |
WO2018119288A1 (en) * | 2016-12-22 | 2018-06-28 | Sanofi | Anti-human cxcr3 antibodies for treatment of vitiligo |
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CA2122732C (en) | 1991-11-25 | 2008-04-08 | Marc D. Whitlow | Multivalent antigen-binding proteins |
US6140064A (en) * | 1996-09-10 | 2000-10-31 | Theodor-Kocher Institute | Method of detecting or identifying ligands, inhibitors or promoters of CXC chemokine receptor 3 |
WO1999029888A1 (en) | 1997-12-05 | 1999-06-17 | The Scripps Research Institute | Humanization of murine antibody |
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WO2013109974A2 (en) * | 2012-01-20 | 2013-07-25 | Genzyme Corporation | Anti-cxcr3 antibodies |
WO2018119288A1 (en) * | 2016-12-22 | 2018-06-28 | Sanofi | Anti-human cxcr3 antibodies for treatment of vitiligo |
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US20210061917A1 (en) | 2021-03-04 |
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