JP2021513844A5 - - Google Patents

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Publication number
JP2021513844A5
JP2021513844A5 JP2020543351A JP2020543351A JP2021513844A5 JP 2021513844 A5 JP2021513844 A5 JP 2021513844A5 JP 2020543351 A JP2020543351 A JP 2020543351A JP 2020543351 A JP2020543351 A JP 2020543351A JP 2021513844 A5 JP2021513844 A5 JP 2021513844A5
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JP
Japan
Prior art keywords
antibody
occupied
conjugated
item
seq
Prior art date
Application number
JP2020543351A
Other languages
English (en)
Japanese (ja)
Other versions
JP7402807B2 (ja
JP2021513844A (ja
JPWO2019161174A5 (https=
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/018182 external-priority patent/WO2019161174A1/en
Publication of JP2021513844A publication Critical patent/JP2021513844A/ja
Publication of JP2021513844A5 publication Critical patent/JP2021513844A5/ja
Publication of JPWO2019161174A5 publication Critical patent/JPWO2019161174A5/ja
Priority to JP2023067166A priority Critical patent/JP2023089195A/ja
Application granted granted Critical
Publication of JP7402807B2 publication Critical patent/JP7402807B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020543351A 2018-02-15 2019-02-15 グリピカン3抗体およびそのコンジュゲート Active JP7402807B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023067166A JP2023089195A (ja) 2018-02-15 2023-04-17 グリピカン3抗体およびそのコンジュゲート

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862631353P 2018-02-15 2018-02-15
US62/631,353 2018-02-15
PCT/US2019/018182 WO2019161174A1 (en) 2018-02-15 2019-02-15 Glypican 3 antibodies and conjugates thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023067166A Division JP2023089195A (ja) 2018-02-15 2023-04-17 グリピカン3抗体およびそのコンジュゲート

Publications (4)

Publication Number Publication Date
JP2021513844A JP2021513844A (ja) 2021-06-03
JP2021513844A5 true JP2021513844A5 (https=) 2022-02-22
JPWO2019161174A5 JPWO2019161174A5 (https=) 2022-02-22
JP7402807B2 JP7402807B2 (ja) 2023-12-21

Family

ID=67620075

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020543351A Active JP7402807B2 (ja) 2018-02-15 2019-02-15 グリピカン3抗体およびそのコンジュゲート
JP2023067166A Pending JP2023089195A (ja) 2018-02-15 2023-04-17 グリピカン3抗体およびそのコンジュゲート

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023067166A Pending JP2023089195A (ja) 2018-02-15 2023-04-17 グリピカン3抗体およびそのコンジュゲート

Country Status (13)

Country Link
US (2) US11819553B2 (https=)
EP (1) EP3752534A4 (https=)
JP (2) JP7402807B2 (https=)
KR (1) KR20200121317A (https=)
CN (1) CN111712520A (https=)
AR (1) AR114112A1 (https=)
AU (1) AU2019220700A1 (https=)
CA (1) CA3090251A1 (https=)
IL (1) IL276514B2 (https=)
MX (1) MX2020008030A (https=)
SG (1) SG11202007073SA (https=)
TW (1) TWI851552B (https=)
WO (1) WO2019161174A1 (https=)

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MX2019001302A (es) 2016-08-09 2019-06-12 Seattle Genetics Inc Conjugados de farmaco con enlazadores autoestabilizantes que tienen propiedades fisioquimicas mejoradas.
AR114112A1 (es) 2018-02-15 2020-07-22 Seattle Genetics Inc Anticuerpos de glipicano 3 y conjugados de los mismos
CA3170023A1 (en) * 2020-02-27 2021-09-02 Nanjing Legend Biotech Co., Ltd. Antibodies and chimeric antigen receptors targeting glypican-3 (gpc3) and methods of use thereof
WO2021207701A1 (en) 2020-04-10 2021-10-14 Seagen Inc. Charge variant linkers
EP4146702A4 (en) * 2020-05-07 2024-07-10 Phanes Therapeutics, Inc. Anti-tumor associated antigen antibodies and uses thereof
AU2022238571A1 (en) 2021-03-18 2023-09-14 Seagen Inc. Selective drug release from internalized conjugates of biologically active compounds
CN112921005B (zh) * 2021-04-14 2023-07-07 中国农业科学院兰州兽医研究所 一株杂交瘤细胞株及其产生的犬细小病毒vp2蛋白单克隆抗体和应用
CA3221398A1 (en) 2021-05-28 2022-12-01 Seagen Inc. Anthracycline antibody conjugates
IL310866A (en) * 2021-08-19 2024-04-01 Adicet Therapeutics Inc Methods for the detection of membrane-bound glypican-3
WO2023045151A1 (en) * 2021-09-24 2023-03-30 Zhejiang Shimai Pharmaceutical Co., Ltd. Antibodies against gpc3 and uses thereof
IL315508A (en) 2022-03-17 2024-11-01 Seagen Inc Camptothecin conjugates
WO2023207475A1 (zh) * 2022-04-24 2023-11-02 昱言科技(北京)有限公司 靶向gpc3的单克隆抗体和包含此抗体的抗体药物缀合物
CN119894536A (zh) * 2022-09-22 2025-04-25 乐普生物科技股份有限公司 Gpc3抗体药物偶联物及其应用
CN119968398A (zh) * 2022-11-28 2025-05-09 四川科伦博泰生物医药股份有限公司 靶向gpc3的抗体及其用途
WO2024129756A1 (en) 2022-12-13 2024-06-20 Seagen Inc. Site-specific engineered cysteine antibody drug conjugates
CN119424671A (zh) * 2023-08-01 2025-02-14 上海新理念生物医药科技有限公司 含糖基吡啶型连接子的抗体药物偶联物
WO2025090774A1 (en) 2023-10-24 2025-05-01 Seagen Inc. Chemotherapeutic compounds and methods of use

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Publication number Priority date Publication date Assignee Title
US7361336B1 (en) 1997-09-18 2008-04-22 Ivan Bergstein Methods of cancer therapy targeted against a cancer stem line
CA2451493C (en) 2001-06-22 2016-08-23 Chugai Seiyaku Kabushiki Kaisha Cell growth inhibitors containing anti-glypican 3 antibody
WO2004022597A1 (ja) 2002-09-04 2004-03-18 Chugai Seiyaku Kabushiki Kaisha Gpc3の血中可溶化n端ペプチドに対する抗体
CN1842540B (zh) * 2004-07-09 2012-07-04 中外制药株式会社 抗-磷脂酰肌醇蛋白聚糖3抗体
BR112012012912A2 (pt) 2009-11-30 2016-10-25 Biotest Ag anticorpo ou fragmento do mesmo, ácido nucleico, vetor, célula hospedeira, método para a produção de um anticorpo ou um fragmento do mesmo, composição farmacêutica, método para tratar ou prevenir uma condição médica em um indivíduo, uso de um anticorpo ou fragmento do mesmo e métodos in vitro para neutralizar il-10 em uma amostra e para detectar a presença de il-10 em uma amostra.
CN113933504A (zh) * 2014-05-08 2022-01-14 中外制药株式会社 对gpc3靶向治疗剂疗法有效的患者施用的gpc3靶向治疗剂
WO2015179658A2 (en) 2014-05-22 2015-11-26 Genentech, Inc. Anti-gpc3 antibodies and immunoconjugates
EP2963057A1 (en) 2014-07-02 2016-01-06 Calypso Biotech SA Antibodies to IL-15
SI3900742T1 (sl) * 2014-09-11 2024-10-30 Seagen Inc. Ciljana dostava zdravilnih snovi, ki vsebujejo terciarne amine
WO2017181109A1 (en) * 2016-04-15 2017-10-19 Michael Molloy Anti-human vista antibodies and use thereof
US20170326249A1 (en) * 2016-05-10 2017-11-16 Bristol-Myers Squibb Company Antibody-drug conjugate of an anti-glypican-3 antibody and a tubulysin analog, preparation and uses
AR114112A1 (es) 2018-02-15 2020-07-22 Seattle Genetics Inc Anticuerpos de glipicano 3 y conjugados de los mismos

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