JP2021506275A5 - - Google Patents

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Publication number
JP2021506275A5
JP2021506275A5 JP2020532815A JP2020532815A JP2021506275A5 JP 2021506275 A5 JP2021506275 A5 JP 2021506275A5 JP 2020532815 A JP2020532815 A JP 2020532815A JP 2020532815 A JP2020532815 A JP 2020532815A JP 2021506275 A5 JP2021506275 A5 JP 2021506275A5
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JP
Japan
Prior art keywords
tnfr
nucleic acid
chimeric
item
domain
Prior art date
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Application number
JP2020532815A
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English (en)
Japanese (ja)
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JP2021506275A (ja
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Priority claimed from GBGB1720949.5A external-priority patent/GB201720949D0/en
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Publication of JP2021506275A publication Critical patent/JP2021506275A/ja
Publication of JP2021506275A5 publication Critical patent/JP2021506275A5/ja
Withdrawn legal-status Critical Current

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JP2020532815A 2017-12-15 2018-12-14 細胞 Withdrawn JP2021506275A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1720949.5 2017-12-15
GBGB1720949.5A GB201720949D0 (en) 2017-12-15 2017-12-15 Cell
PCT/GB2018/053629 WO2019116046A1 (en) 2017-12-15 2018-12-14 Cell

Publications (2)

Publication Number Publication Date
JP2021506275A JP2021506275A (ja) 2021-02-22
JP2021506275A5 true JP2021506275A5 (https=) 2021-11-25

Family

ID=61009002

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020532815A Withdrawn JP2021506275A (ja) 2017-12-15 2018-12-14 細胞

Country Status (9)

Country Link
US (1) US12304942B2 (https=)
EP (2) EP4628503A3 (https=)
JP (1) JP2021506275A (https=)
CN (1) CN111479918A (https=)
AU (1) AU2018383084A1 (https=)
CA (1) CA3086360A1 (https=)
ES (1) ES3039696T3 (https=)
GB (1) GB201720949D0 (https=)
WO (1) WO2019116046A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220145325A1 (en) 2019-03-08 2022-05-12 Autolus Limited Compositions and methods comprising engineered chimeric antigen receptor and modulator of car
JP7755597B2 (ja) * 2020-04-09 2025-10-16 オートラス リミテッド 細胞
US20230133554A1 (en) * 2020-04-09 2023-05-04 Autolus Limited Molecule
CN116194124A (zh) * 2020-07-31 2023-05-30 中外制药株式会社 包含表达嵌合受体的细胞的药物组合物
WO2022036495A1 (en) 2020-08-17 2022-02-24 Utc Therapeutics Inc. Lymphocytes-antigen presenting cells co-stimulators and uses thereof
EP4277639A4 (en) * 2021-01-15 2025-03-05 Seattle Children's Hospital d/b/a Seattle Children's Research Institute HYBRID AND TRUNCATED IMMUNE CELL PROTEINS
KR20250004736A (ko) * 2022-04-07 2025-01-08 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 조작된 자연 살해 세포의 활성화 및 증대 및 항체와의 조합을 위한 방법
EP4551692A1 (en) * 2022-07-01 2025-05-14 Fate Therapeutics, Inc. Enhancing effector cell durability and efficacy in adoptive cell therapies
CN120535659B (zh) * 2025-07-29 2025-10-17 苏州大学 一种骨靶向的三聚体蛋白及其制备方法与应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7214658B2 (en) * 2004-07-06 2007-05-08 Tact Ip, Llc Method of delivering a TNF antagonist to the brain of a human by perispinal administration without direct intrathecal injection
WO2000063374A1 (en) 1999-04-16 2000-10-26 Celltech Therapeutics Limited Synthetic transmembrane components
AU2002221780A1 (en) 2000-10-31 2002-05-15 F.Hoffmann-La Roche Ag Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof
US20050113564A1 (en) 2003-11-05 2005-05-26 St. Jude Children's Research Hospital Chimeric receptors with 4-1BB stimulatory signaling domain
US20130266551A1 (en) 2003-11-05 2013-10-10 St. Jude Children's Research Hospital, Inc. Chimeric receptors with 4-1bb stimulatory signaling domain
WO2013033626A2 (en) 2011-08-31 2013-03-07 Trustees Of Dartmouth College Nkp30 receptor targeted therapeutics
GB201206559D0 (en) 2012-04-13 2012-05-30 Ucl Business Plc Polypeptide
TWI719942B (zh) * 2014-07-21 2021-03-01 瑞士商諾華公司 使用cd33嵌合抗原受體治療癌症
EP3230310B1 (en) * 2014-12-08 2019-06-12 The U.S.A. as represented by the Secretary, Department of Health and Human Services Anti-cd70 chimeric antigen receptors
GB201507368D0 (en) 2015-04-30 2015-06-17 Ucl Business Plc Cell
CN106467906B (zh) * 2015-08-20 2019-09-27 北京马力喏生物科技有限公司 构建体、转基因淋巴细胞及其制备方法和用途
US20220145325A1 (en) 2019-03-08 2022-05-12 Autolus Limited Compositions and methods comprising engineered chimeric antigen receptor and modulator of car
JP7755597B2 (ja) 2020-04-09 2025-10-16 オートラス リミテッド 細胞

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