JP2021503292A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2021503292A5 JP2021503292A5 JP2020527909A JP2020527909A JP2021503292A5 JP 2021503292 A5 JP2021503292 A5 JP 2021503292A5 JP 2020527909 A JP2020527909 A JP 2020527909A JP 2020527909 A JP2020527909 A JP 2020527909A JP 2021503292 A5 JP2021503292 A5 JP 2021503292A5
- Authority
- JP
- Japan
- Prior art keywords
- library
- members
- sub
- cdr3
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023084817A JP7628153B2 (ja) | 2017-11-20 | 2023-05-23 | ｍＲＮＡディスプレイ抗体ライブラリー及び方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762588914P | 2017-11-20 | 2017-11-20 | |
| US62/588,914 | 2017-11-20 | ||
| PCT/US2018/061592 WO2019099882A2 (en) | 2017-11-20 | 2018-11-16 | mRNA DISPLAY ANTIBODY LIBRARY AND METHODS |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023084817A Division JP7628153B2 (ja) | 2017-11-20 | 2023-05-23 | ｍＲＮＡディスプレイ抗体ライブラリー及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021503292A JP2021503292A (ja) | 2021-02-12 |
| JP2021503292A5 true JP2021503292A5 (https=) | 2021-08-12 |
| JP7291700B2 JP7291700B2 (ja) | 2023-06-15 |
Family
ID=66534257
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020527909A Active JP7291700B2 (ja) | 2017-11-20 | 2018-11-16 | ｍＲＮＡディスプレイ抗体ライブラリー及び方法 |
| JP2023084817A Active JP7628153B2 (ja) | 2017-11-20 | 2023-05-23 | ｍＲＮＡディスプレイ抗体ライブラリー及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023084817A Active JP7628153B2 (ja) | 2017-11-20 | 2023-05-23 | ｍＲＮＡディスプレイ抗体ライブラリー及び方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11015188B2 (https=) |
| EP (3) | EP3713964B1 (https=) |
| JP (2) | JP7291700B2 (https=) |
| KR (2) | KR102875544B1 (https=) |
| CN (2) | CN118206640A (https=) |
| AU (1) | AU2018367622B2 (https=) |
| CA (1) | CA3082172C (https=) |
| ES (1) | ES2969081T3 (https=) |
| IL (2) | IL274780B2 (https=) |
| TW (4) | TWI693235B (https=) |
| WO (1) | WO2019099882A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11034951B2 (en) | 2017-11-20 | 2021-06-15 | Nantbio, Inc. | mRNA display antibody library and methods |
| IL274780B2 (en) | 2017-11-20 | 2025-04-01 | Nantbio Inc | mRNA library for antibody display and methods |
| CN113366104B (zh) * | 2019-01-31 | 2024-03-26 | 南特生物科学公司 | mRNA展示抗体文库和方法 |
| WO2021061842A1 (en) * | 2019-09-23 | 2021-04-01 | Twist Bioscience Corporation | Variant nucleic acid libraries for single domain antibodies |
| EP4314075A4 (en) | 2021-03-24 | 2025-04-09 | Twist Bioscience Corporation | VARIANT NUCLEIC ACID BANKS FOR CD3 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7667004B2 (en) * | 2001-04-17 | 2010-02-23 | Abmaxis, Inc. | Humanized antibodies against vascular endothelial growth factor |
| CN1672160B (zh) * | 2002-05-20 | 2010-06-09 | 埃博马可西斯公司 | 基于前导抗体的结构构建抗体文库的方法 |
| US20040067532A1 (en) | 2002-08-12 | 2004-04-08 | Genetastix Corporation | High throughput generation and affinity maturation of humanized antibody |
| CA2572961C (en) * | 2004-07-06 | 2016-08-16 | Bioren, Inc. | Universal antibody libraries |
| GB0500099D0 (en) | 2005-01-05 | 2005-02-09 | Cambridge Antibody Tech | Methods and means relating to protein variants |
| KR20080073293A (ko) | 2005-10-14 | 2008-08-08 | 메디뮨 엘엘씨 | 항체 라이브러리의 세포 디스플레이 |
| JP2009515516A (ja) * | 2005-11-14 | 2009-04-16 | バイオレン・インク | 推定成熟ｃｄｒのブラスティングならびにコホートライブラリの作製およびスクリーニングによる抗体の超ヒト化 |
| EP2069558B1 (en) | 2006-10-02 | 2013-05-01 | Sea Lane Biotechnologies,llc. | Design and construction of diverse synthetic peptide and polypeptide libraries |
| US20100137156A1 (en) * | 2007-03-09 | 2010-06-03 | Leung Shui-On | Construction and use of a functionally human antibody library with maximized repertoire diversity |
| JP2011507519A (ja) * | 2007-12-19 | 2011-03-10 | セントコア・オーソ・バイオテツク・インコーポレーテツド | ｐＩＸ又はｐＶＩＩへの融合を介したヒトデノボｐＩＸファージディスプレイライブラリの設計及び作製、ベクター、抗体、及び方法 |
| KR100961392B1 (ko) | 2008-04-15 | 2010-06-07 | 이화여자대학교 산학협력단 | 항체 파지 표면제시 라이브러리 제조방법, 상기 방법에의해 제조된 항체 파지 표면제시 라이브러리, 상기 항체파지 표면제시 라이브러리 유전자를 포함한 파지미드 벡터 |
| MX2011003381A (es) * | 2008-09-30 | 2011-04-21 | Abbott Lab | Metodo mejorado para despliegue de arn. |
| RU2011117213A (ru) * | 2008-09-30 | 2012-11-10 | Эббот Лэборетриз (Us) | Улучшенные библиотеки антител |
| DK2356270T3 (da) | 2008-11-07 | 2016-12-12 | Fabrus Llc | Kombinatoriske antistofbiblioteker og anvendelser deraf |
| EP2528944B1 (en) | 2010-01-29 | 2015-08-12 | MorphoSys AG | Rodent combinatorial antibody libraries |
| KR101694832B1 (ko) | 2014-12-31 | 2017-01-12 | 앱클론(주) | 항체 라이브러리 및 그의 제작방법 |
| EP3246434A1 (en) | 2015-01-13 | 2017-11-22 | Ewha University-Industry Collaboration Foundation | Method for preparing novel antibody library and library prepared thereby |
| WO2017186928A1 (en) * | 2016-04-29 | 2017-11-02 | Curevac Ag | Rna encoding an antibody |
| IL274780B2 (en) | 2017-11-20 | 2025-04-01 | Nantbio Inc | mRNA library for antibody display and methods |
| US11034951B2 (en) | 2017-11-20 | 2021-06-15 | Nantbio, Inc. | mRNA display antibody library and methods |
| CN113366104B (zh) | 2019-01-31 | 2024-03-26 | 南特生物科学公司 | mRNA展示抗体文库和方法 |
-
2018
- 2018-11-16 IL IL274780A patent/IL274780B2/en unknown
- 2018-11-16 CA CA3082172A patent/CA3082172C/en active Active
- 2018-11-16 JP JP2020527909A patent/JP7291700B2/ja active Active
- 2018-11-16 EP EP18878248.6A patent/EP3713964B1/en active Active
- 2018-11-16 AU AU2018367622A patent/AU2018367622B2/en active Active
- 2018-11-16 CN CN202410307390.0A patent/CN118206640A/zh active Pending
- 2018-11-16 KR KR1020237043350A patent/KR102875544B1/ko active Active
- 2018-11-16 WO PCT/US2018/061592 patent/WO2019099882A2/en not_active Ceased
- 2018-11-16 ES ES18878248T patent/ES2969081T3/es active Active
- 2018-11-16 EP EP24151054.4A patent/EP4368716B1/en active Active
- 2018-11-16 IL IL316884A patent/IL316884A/en unknown
- 2018-11-16 CN CN201880074681.2A patent/CN111511768B/zh active Active
- 2018-11-16 KR KR1020207017165A patent/KR102615744B1/ko active Active
- 2018-11-16 US US16/193,999 patent/US11015188B2/en active Active
- 2018-11-16 EP EP25198182.5A patent/EP4644544A3/en active Pending
- 2018-11-20 TW TW107141333A patent/TWI693235B/zh active
- 2018-11-20 TW TW112138352A patent/TWI877823B/zh active
- 2018-11-20 TW TW114105419A patent/TW202521587A/zh unknown
- 2018-11-20 TW TW109109861A patent/TWI821545B/zh active
-
2021
- 2021-04-21 US US17/236,978 patent/US11912756B2/en active Active
-
2023
- 2023-05-23 JP JP2023084817A patent/JP7628153B2/ja active Active
- 2023-12-13 US US18/538,648 patent/US20240190945A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021503292A5 (https=) | ||
| US20250059262A1 (en) | Method of preparing ph-dependent antibodies | |
| US8735331B2 (en) | Display library for antibody selection | |
| KR102290949B1 (ko) | 신규 항체 라이브러리 제조방법 및 이로부터 제조된 라이브러리 | |
| Yang et al. | Construction of a large synthetic human scFv library with six diversified CDRs and high functional diversity | |
| US10677787B2 (en) | Antibody screening methods | |
| JP2017221200A (ja) | 二重標的化 | |
| JP2018522888A5 (https=) | ||
| JP2018517899A (ja) | タンパク質の特徴を改善する方法 | |
| JP2024001073A5 (https=) | ||
| KR102615744B1 (ko) | mRNA 디스플레이 항체 라이브러리 및 방법(mRNA DISPLAY ANTIBODY LIBRARY AND METHODS) | |
| JP2010508290A (ja) | ヒトに適合するモノクローナル抗体に使用するための方法 | |
| CN104981482A (zh) | 双靶向作用 | |
| JP2021529524A5 (https=) | ||
| JPWO2022111425A5 (https=) | ||
| Padoa et al. | Engineered antibodies: A new tool for use in diabetes research | |
| Sixholo et al. | Improving the characteristics of a mycobacterial 16 kDa-specific chicken scFv | |
| CN112424221B (zh) | 抗体文库和使用抗体文库的抗体筛选方法 | |
| WO2010130824A2 (en) | Collections and uses thereof | |
| JPWO2021207072A5 (https=) | ||
| JPWO2020229842A5 (https=) | ||
| JP7821159B2 (ja) | Ｂｃｍａと結合する単一可変ドメイン及び抗原結合分子 | |
| KR20250091367A (ko) | 개 pdl-1 항체 및 이의 용도 | |
| HK40047350B (en) | Antibody screening methods | |
| HK40047350A (en) | Antibody screening methods |