JP2021503008A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2021503008A5 JP2021503008A5 JP2020544558A JP2020544558A JP2021503008A5 JP 2021503008 A5 JP2021503008 A5 JP 2021503008A5 JP 2020544558 A JP2020544558 A JP 2020544558A JP 2020544558 A JP2020544558 A JP 2020544558A JP 2021503008 A5 JP2021503008 A5 JP 2021503008A5
- Authority
- JP
- Japan
- Prior art keywords
- hematopoietic stem
- patient
- optionally substituted
- cells
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 Cc1c(CI*)c2nc(*)c(*)[n]2c(*)c1* Chemical compound Cc1c(CI*)c2nc(*)c(*)[n]2c(*)c1* 0.000 description 2
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762579776P | 2017-10-31 | 2017-10-31 | |
| US62/579,776 | 2017-10-31 | ||
| US201762596661P | 2017-12-08 | 2017-12-08 | |
| US62/596,661 | 2017-12-08 | ||
| PCT/US2018/058562 WO2019089833A1 (en) | 2017-10-31 | 2018-10-31 | Compositions and methods for hematopoietic stem and progenitor cell transplant therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021503008A JP2021503008A (ja) | 2021-02-04 |
| JP2021503008A5 true JP2021503008A5 (https=) | 2021-12-09 |
Family
ID=64650470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020544558A Pending JP2021503008A (ja) | 2017-10-31 | 2018-10-31 | 造血幹細胞および前駆細胞移植療法のための組成物および方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20190343885A1 (https=) |
| EP (1) | EP3703715A1 (https=) |
| JP (1) | JP2021503008A (https=) |
| CN (1) | CN111683669A (https=) |
| AU (1) | AU2018358054A1 (https=) |
| CA (1) | CA3079404A1 (https=) |
| WO (1) | WO2019089833A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201841916A (zh) | 2017-04-12 | 2018-12-01 | 美商麥珍塔治療學股份有限公司 | 芳香烴受體拮抗劑及其用途 |
| US20200338132A1 (en) * | 2018-01-03 | 2020-10-29 | Magenta Therapeutics Inc. | Compositions and methods for the expansion of hematopoietic stem and progenitor cells and treatment of inherited metabolic disorders |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5233044A (en) | 1989-06-08 | 1993-08-03 | Millipore Corporation | Active esters for solid phase peptide synthesis |
| US5021409A (en) | 1989-12-21 | 1991-06-04 | Johnson Matthey Plc | Antiviral cyclic polyamines |
| US5512421A (en) | 1991-02-19 | 1996-04-30 | The Regents Of The University Of California | Generation, concentration and efficient transfer of VSV-G pseudotyped retroviral vectors |
| GB9126677D0 (en) | 1991-12-16 | 1992-02-12 | Johnson Matthey Plc | Improvements in chemical compounds |
| DK0752248T3 (da) | 1992-11-13 | 2000-11-13 | Idec Pharma Corp | Terapeutisk anvendelse af kimæriske og radioaktivt mærkede antistoffer mod humant B-lymfocytbegrænset differentieringsantig |
| ES2210255T3 (es) | 1993-06-08 | 2004-07-01 | Smithkline Beecham Corporation | Metodos para mejorar la actividad biologica de quimiocinas. |
| US6447766B1 (en) | 1993-06-08 | 2002-09-10 | Smithkline Beecham Corporation | Method of mobilizing hematopoietic stem cells |
| GB9400411D0 (en) | 1994-01-11 | 1994-03-09 | Johnson Matthey Plc | Improvements in chemical compounds |
| US5547892A (en) | 1995-04-27 | 1996-08-20 | Taiwan Semiconductor Manufacturing Company | Process for forming stacked contacts and metal contacts on static random access memory having thin film transistors |
| US6506770B1 (en) | 1996-06-06 | 2003-01-14 | Anormed, Inc. | Antiviral compounds |
| US5801030A (en) | 1995-09-01 | 1998-09-01 | Genvec, Inc. | Methods and vectors for site-specific recombination |
| KR100463630B1 (ko) | 1997-02-11 | 2005-05-25 | 말린크로트, 인코포레이티드 | 고상 펩티드 합성용 반응기 및 방법_ |
| ES2156581T5 (es) | 1998-03-30 | 2015-01-21 | Northwest Biotherapeutics, Inc. | Aplicaciones terapéuticas y diagnósticas basadas en el papel del gen CXCR-4 en la tumorigénesis |
| AP1654A (en) | 1999-03-24 | 2006-09-01 | Anormed Inc | Chemokine receptor binding heterocyclic compounds. |
| AU2334301A (en) | 1999-12-17 | 2001-06-25 | Anormed Inc. | Chemokine receptor binding heterocyclic compounds |
| DE10120829A1 (de) | 2000-04-27 | 2001-12-20 | Max Delbrueck Centrum | Sleeping Beauty, ein Transposonvektor mit breitem Wirtsbereich für die genetische Transformation bei Wirbeltieren |
| EP1286684B1 (en) | 2000-05-09 | 2004-04-28 | The University Of British Columbia | use of cxcr4 antagonists for treating autoimmune diseases and cancer |
| MXPA02012067A (es) | 2000-06-05 | 2004-08-19 | Univ Columbia | Identificacion y uso de celulas endoteliales precursoras derivadas de medula osea par mejorar la funcion del miocardio despues de dano isquemico. |
| JP5170934B2 (ja) | 2001-08-16 | 2013-03-27 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 改良ｄｎａリポフェクションならびに／または徐放性プロドラッグおよび薬物療法のための試薬の合成と使用 |
| US20030199464A1 (en) | 2002-04-23 | 2003-10-23 | Silviu Itescu | Regeneration of endogenous myocardial tissue by induction of neovascularization |
| US7683036B2 (en) | 2003-07-31 | 2010-03-23 | Regulus Therapeutics Inc. | Oligomeric compounds and compositions for use in modulation of small non-coding RNAs |
| JP2008509928A (ja) | 2004-08-13 | 2008-04-03 | アノーメド インコーポレイテッド | 前駆／幹細胞を動員するためのケモカインの組み合わせ |
| ES2582091T3 (es) | 2005-10-18 | 2016-09-09 | Precision Biosciences | Meganucleasas diseñadas racionalmente con especificidad de secuencia y afinidad de unión a ADN alteradas |
| CN101421393B (zh) * | 2006-02-14 | 2013-08-14 | 塞勒兰特治疗公司 | 提高造血干细胞植入的方法和组合物 |
| WO2007145227A1 (ja) | 2006-06-14 | 2007-12-21 | Chugai Seiyaku Kabushiki Kaisha | 造血幹細胞増加促進剤 |
| EP1995316A1 (de) | 2007-05-25 | 2008-11-26 | Qiagen GmbH | Verfahren zur schonenden Zellaufreinigung, Zellgewinnung und Transfektion von Zellen |
| EP2009095A1 (en) | 2007-06-28 | 2008-12-31 | Innovalor AG | Method of generating glucose-responsive cells |
| EP2215223B1 (en) | 2007-10-31 | 2013-05-01 | Precision Biosciences, Inc. | Rationally-designed single-chain meganucleases with non-palindromic recognition sequences |
| PE20100362A1 (es) | 2008-10-30 | 2010-05-27 | Irm Llc | Derivados de purina que expanden las celulas madre hematopoyeticas |
| WO2010085699A2 (en) | 2009-01-23 | 2010-07-29 | The Johns Hopkins University | Mammalian piggybac transposon and methods of use |
| EP2270025A1 (en) | 2009-06-29 | 2011-01-05 | Centre National pour la Recherche Scientifique (CNRS) | Solid phase peptide synthesis of peptide alcohols |
| US9388212B2 (en) | 2013-02-21 | 2016-07-12 | Chemical & Biopharmaceutical Laboratories Of Patras S.A. | Solid phase peptide synthesis via side chain attachment |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| KR102503695B1 (ko) * | 2013-02-28 | 2023-02-23 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 줄기세포를 동원하기 위한 방법 및 조성물 |
| US9169287B2 (en) | 2013-03-15 | 2015-10-27 | Massachusetts Institute Of Technology | Solid phase peptide synthesis processes and associated systems |
| HK1256681A1 (zh) * | 2015-04-06 | 2019-10-04 | President And Fellows Of Harvard College | 用於非清髓性预处理的组合物和方法 |
-
2018
- 2018-10-31 EP EP18815378.7A patent/EP3703715A1/en not_active Withdrawn
- 2018-10-31 CA CA3079404A patent/CA3079404A1/en active Pending
- 2018-10-31 WO PCT/US2018/058562 patent/WO2019089833A1/en not_active Ceased
- 2018-10-31 CN CN201880085039.4A patent/CN111683669A/zh active Pending
- 2018-10-31 AU AU2018358054A patent/AU2018358054A1/en not_active Abandoned
- 2018-10-31 JP JP2020544558A patent/JP2021503008A/ja active Pending
- 2018-10-31 US US16/177,254 patent/US20190343885A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021502824A5 (https=) | ||
| Jurewicz et al. | Congenic mesenchymal stem cell therapy reverses hyperglycemia in experimental type 1 diabetes | |
| JP2021505172A5 (https=) | ||
| Lu et al. | Unmanipulated haploidentical hematopoietic stem cell transplantation achieved outcomes comparable with matched unrelated donor transplantation in young acquired severe aplastic anemia | |
| Arber et al. | Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation | |
| Terrell et al. | Mixed hematopoietic or T-cell chimerism above a minimal threshold restores perforin-dependent immune regulation in perforin-deficient mice | |
| Taylor et al. | Insights into the mechanism of FTY720 and compatibility with regulatory T cells for the inhibition of graft-versus-host disease (GVHD) | |
| Chhabra et al. | The immunosuppressive role of adenosine A2A receptors in ischemia reperfusion injury and islet transplantation | |
| Bacigalupo et al. | Haploidentical donor transplants for severe aplastic anemia | |
| Taylor et al. | Combined effects of calcineurin inhibitors or sirolimus with anti-CD40L mAb on alloengraftment under nonmyeloablative conditions | |
| JP2018502117A5 (https=) | ||
| US20160243168A1 (en) | Adoptive cell transfer methods | |
| JP2021503008A5 (https=) | ||
| Picardi et al. | Brentuximab vedotin followed by bendamustine supercharge for refractory or relapsed Hodgkin lymphoma | |
| Jaiswal et al. | CTLA4Ig in an extended schedule along with sirolimus improves outcome with a distinct pattern of immune reconstitution following post-transplantation cyclophosphamide-based haploidentical transplantation for hemoglobinopathies | |
| Sodani et al. | T cell-depleted hla-haploidentical stem cell transplantation in thalassemia young patients | |
| TW202309077A (zh) | 用於治療實性瘤的靶向ｃｄ７０的基因工程化免疫細胞 | |
| Gong et al. | Alternative transplantation with post-transplantation cyclophosphamide in aplastic anemia: a retrospective report from the BMF-WG of Hunan Province, China | |
| CA2966217A1 (en) | Il-12 compositions and methods of use in hematopoietic recovery | |
| Foà et al. | Induction and persistence of complete remission in a resistant acute myeloid leukemia patient after treatment with recombinant interleukin-2 | |
| Hara et al. | High doses of gamma globulin and methylprednisolone therapy for idiopathic thrombocytopenic purpura in children | |
| JP2022505199A (ja) | カルボジイミドで処理された寛容化ワクチンによる移植寛容誘導 | |
| CA2120500A1 (en) | Preventing allograft rejection with antibodies to adhesion molecules | |
| Lee et al. | Clinical efficacy and prediction of response to granulocyte transfusion therapy for patients with neutropenia-related infections | |
| JP2025063190A (ja) | リンホトキシンアルファ遮断剤によりターゲットされた制御性ｔ細胞及びその使用 |