JP2021505172A5 - - Google Patents
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- JP2021505172A5 JP2021505172A5 JP2020531468A JP2020531468A JP2021505172A5 JP 2021505172 A5 JP2021505172 A5 JP 2021505172A5 JP 2020531468 A JP2020531468 A JP 2020531468A JP 2020531468 A JP2020531468 A JP 2020531468A JP 2021505172 A5 JP2021505172 A5 JP 2021505172A5
- Authority
- JP
- Japan
- Prior art keywords
- donor
- disease
- cells
- population
- hematopoietic stem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023188499A JP2024023226A (ja) | 2017-12-06 | 2023-11-02 | 造血幹細胞及び前駆細胞を動員させるための投薬レジメン |
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/834,017 | 2017-12-06 | ||
| US15/834,017 US10058573B1 (en) | 2017-12-06 | 2017-12-06 | Dosing regimens for the mobilization of hematopoietic stem cells |
| US201762596056P | 2017-12-07 | 2017-12-07 | |
| US62/596,056 | 2017-12-07 | ||
| US16/101,676 | 2018-08-13 | ||
| US16/101,676 US20190167726A1 (en) | 2017-12-06 | 2018-08-13 | Dosing Regimens for the Mobilization of Hematopoietic Stem Cells |
| US201862753656P | 2018-10-31 | 2018-10-31 | |
| US62/753,656 | 2018-10-31 | ||
| US201862773954P | 2018-11-30 | 2018-11-30 | |
| US62/773,954 | 2018-11-30 | ||
| PCT/US2018/064335 WO2019113375A2 (en) | 2017-12-06 | 2018-12-06 | Dosing regimens for the mobilization of hematopoietic stem and progenitor cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023188499A Division JP2024023226A (ja) | 2017-12-06 | 2023-11-02 | 造血幹細胞及び前駆細胞を動員させるための投薬レジメン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021505172A JP2021505172A (ja) | 2021-02-18 |
| JP2021505172A5 true JP2021505172A5 (https=) | 2022-01-11 |
Family
ID=66749948
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020531468A Pending JP2021505172A (ja) | 2017-12-06 | 2018-12-06 | 造血幹細胞及び前駆細胞を動員させるための投薬レジメン |
| JP2023188499A Pending JP2024023226A (ja) | 2017-12-06 | 2023-11-02 | 造血幹細胞及び前駆細胞を動員させるための投薬レジメン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023188499A Pending JP2024023226A (ja) | 2017-12-06 | 2023-11-02 | 造血幹細胞及び前駆細胞を動員させるための投薬レジメン |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP3720494A2 (https=) |
| JP (2) | JP2021505172A (https=) |
| KR (1) | KR20200096942A (https=) |
| CN (1) | CN111712262A (https=) |
| AU (1) | AU2018378804B2 (https=) |
| BR (1) | BR112020011186A2 (https=) |
| CA (1) | CA3083783A1 (https=) |
| CO (1) | CO2020007275A2 (https=) |
| IL (2) | IL275077B2 (https=) |
| MX (2) | MX2020005878A (https=) |
| SG (1) | SG11202004913TA (https=) |
| WO (1) | WO2019113375A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11260079B2 (en) | 2017-12-06 | 2022-03-01 | Magenta Therapeutics, Inc. | Dosing regimens for the mobilization of hematopoietic stem and progenitor cells |
| EP4051298A1 (en) * | 2019-11-01 | 2022-09-07 | Magenta Therapeutics, Inc. | Dosing regimens for the mobilization of hematopoietic stem and progentor cells |
| CA3176979A1 (en) * | 2020-04-27 | 2021-11-04 | Anthony Boitano | Methods and compositions for transducing hematopoietic stem and progenitor cells in vivo |
| WO2022197776A1 (en) * | 2021-03-16 | 2022-09-22 | Magenta Therapeutics, Inc. | Dosing regimens for hematopoietic stem cell mobilization for stem cell transplants in multiple myeloma patients |
| CA3258771A1 (en) * | 2022-06-10 | 2023-12-14 | Gpcr Therapeutics, Inc. | GPCR INHIBITORS AND THEIR USES |
Family Cites Families (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4873191A (en) | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5233044A (en) | 1989-06-08 | 1993-08-03 | Millipore Corporation | Active esters for solid phase peptide synthesis |
| US5413923A (en) | 1989-07-25 | 1995-05-09 | Cell Genesys, Inc. | Homologous recombination for universal donor cells and chimeric mammalian hosts |
| US5021409A (en) | 1989-12-21 | 1991-06-04 | Johnson Matthey Plc | Antiviral cyclic polyamines |
| DE69120146T2 (de) | 1990-01-12 | 1996-12-12 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| WO1996033735A1 (en) | 1995-04-27 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| ATE158021T1 (de) | 1990-08-29 | 1997-09-15 | Genpharm Int | Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| PT1024191E (pt) | 1991-12-02 | 2008-12-22 | Medical Res Council | Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos |
| GB9126677D0 (en) | 1991-12-16 | 1992-02-12 | Johnson Matthey Plc | Improvements in chemical compounds |
| US6447766B1 (en) | 1993-06-08 | 2002-09-10 | Smithkline Beecham Corporation | Method of mobilizing hematopoietic stem cells |
| ES2210255T3 (es) | 1993-06-08 | 2004-07-01 | Smithkline Beecham Corporation | Metodos para mejorar la actividad biologica de quimiocinas. |
| GB9400411D0 (en) | 1994-01-11 | 1994-03-09 | Johnson Matthey Plc | Improvements in chemical compounds |
| WO1996034096A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US6506770B1 (en) | 1996-06-06 | 2003-01-14 | Anormed, Inc. | Antiviral compounds |
| US5801030A (en) | 1995-09-01 | 1998-09-01 | Genvec, Inc. | Methods and vectors for site-specific recombination |
| US5916771A (en) | 1996-10-11 | 1999-06-29 | Abgenix, Inc. | Production of a multimeric protein by cell fusion method |
| CA2722378C (en) | 1996-12-03 | 2015-02-03 | Amgen Fremont Inc. | Human antibodies that bind tnf.alpha. |
| KR100463630B1 (ko) | 1997-02-11 | 2005-05-25 | 말린크로트, 인코포레이티드 | 고상 펩티드 합성용 반응기 및 방법_ |
| ES2156581T5 (es) | 1998-03-30 | 2015-01-21 | Northwest Biotherapeutics, Inc. | Aplicaciones terapéuticas y diagnósticas basadas en el papel del gen CXCR-4 en la tumorigénesis |
| AP1654A (en) | 1999-03-24 | 2006-09-01 | Anormed Inc | Chemokine receptor binding heterocyclic compounds. |
| AU2334301A (en) | 1999-12-17 | 2001-06-25 | Anormed Inc. | Chemokine receptor binding heterocyclic compounds |
| EP1286684B1 (en) | 2000-05-09 | 2004-04-28 | The University Of British Columbia | use of cxcr4 antagonists for treating autoimmune diseases and cancer |
| MXPA02012067A (es) | 2000-06-05 | 2004-08-19 | Univ Columbia | Identificacion y uso de celulas endoteliales precursoras derivadas de medula osea par mejorar la funcion del miocardio despues de dano isquemico. |
| US7169750B2 (en) * | 2001-07-31 | 2007-01-30 | Anormed, Inc. | Methods to mobilize progenitor/stem cells |
| DK1411918T3 (da) * | 2001-07-31 | 2012-04-23 | Genzyme Global S A R L | Fremgangsmåder til at mobilisere progenitor/stamceller |
| JP5170934B2 (ja) | 2001-08-16 | 2013-03-27 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 改良dnaリポフェクションならびに/または徐放性プロドラッグおよび薬物療法のための試薬の合成と使用 |
| US20030199464A1 (en) | 2002-04-23 | 2003-10-23 | Silviu Itescu | Regeneration of endogenous myocardial tissue by induction of neovascularization |
| US7683036B2 (en) | 2003-07-31 | 2010-03-23 | Regulus Therapeutics Inc. | Oligomeric compounds and compositions for use in modulation of small non-coding RNAs |
| JP2008509928A (ja) * | 2004-08-13 | 2008-04-03 | アノーメド インコーポレイテッド | 前駆/幹細胞を動員するためのケモカインの組み合わせ |
| US20070033666A1 (en) | 2005-06-24 | 2007-02-08 | Harris Reuben S | Using cytosine deaminases to diminish retroelement transfer from pigs to humans |
| WO2007047882A2 (en) * | 2005-10-18 | 2007-04-26 | Caritas St. Elizabeth Medical Center Of Boston, Inc. | Combination of cxcr4 antagonist and morphogen to increase angiogenesis |
| ES2582091T3 (es) | 2005-10-18 | 2016-09-09 | Precision Biosciences | Meganucleasas diseñadas racionalmente con especificidad de secuencia y afinidad de unión a ADN alteradas |
| US20100003224A1 (en) * | 2006-08-02 | 2010-01-07 | Genzyme Corporation | Combination Therapy |
| CN101500595A (zh) * | 2006-08-07 | 2009-08-05 | 健赞股份有限公司 | 组合治疗 |
| EP1995316A1 (de) | 2007-05-25 | 2008-11-26 | Qiagen GmbH | Verfahren zur schonenden Zellaufreinigung, Zellgewinnung und Transfektion von Zellen |
| EP2009095A1 (en) | 2007-06-28 | 2008-12-31 | Innovalor AG | Method of generating glucose-responsive cells |
| EP2215223B1 (en) | 2007-10-31 | 2013-05-01 | Precision Biosciences, Inc. | Rationally-designed single-chain meganucleases with non-palindromic recognition sequences |
| PE20100362A1 (es) | 2008-10-30 | 2010-05-27 | Irm Llc | Derivados de purina que expanden las celulas madre hematopoyeticas |
| EP2270025A1 (en) | 2009-06-29 | 2011-01-05 | Centre National pour la Recherche Scientifique (CNRS) | Solid phase peptide synthesis of peptide alcohols |
| EP2533629B1 (en) | 2010-02-11 | 2018-11-28 | Recombinetics, Inc. | Methods and materials for producing transgenic artiodactyls |
| MX363013B (es) | 2011-02-25 | 2019-03-04 | Recombinetics Inc | Animales genéticamente modificados y métodos para su obtención. |
| US9388212B2 (en) | 2013-02-21 | 2016-07-12 | Chemical & Biopharmaceutical Laboratories Of Patras S.A. | Solid phase peptide synthesis via side chain attachment |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| EP2946008A4 (en) * | 2013-01-15 | 2016-07-20 | Ohio State Innovation Foundation | PROCESS FOR MOBILIZING HEMATOPOETIC STEM CELLS |
| KR102503695B1 (ko) * | 2013-02-28 | 2023-02-23 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 줄기세포를 동원하기 위한 방법 및 조성물 |
| US9169287B2 (en) | 2013-03-15 | 2015-10-27 | Massachusetts Institute Of Technology | Solid phase peptide synthesis processes and associated systems |
| EP3419617A4 (en) * | 2016-02-26 | 2019-10-23 | President and Fellows of Harvard College | HIGH GRADE TRANSPLANTABLE HEMATOPOETIC STEM CELLS |
| WO2018085574A2 (en) * | 2016-11-02 | 2018-05-11 | Washington University | Compositions comprising an integrin inhibitor and agents which interact with a chemokine and methods of use thereof |
| US10058573B1 (en) * | 2017-12-06 | 2018-08-28 | Magenta Therapeutics, Inc. | Dosing regimens for the mobilization of hematopoietic stem cells |
-
2018
- 2018-12-06 CN CN201880088815.6A patent/CN111712262A/zh active Pending
- 2018-12-06 KR KR1020207019222A patent/KR20200096942A/ko not_active Ceased
- 2018-12-06 IL IL275077A patent/IL275077B2/en unknown
- 2018-12-06 IL IL315735A patent/IL315735A/en unknown
- 2018-12-06 BR BR112020011186-4A patent/BR112020011186A2/pt unknown
- 2018-12-06 EP EP18829615.6A patent/EP3720494A2/en active Pending
- 2018-12-06 MX MX2020005878A patent/MX2020005878A/es unknown
- 2018-12-06 WO PCT/US2018/064335 patent/WO2019113375A2/en not_active Ceased
- 2018-12-06 JP JP2020531468A patent/JP2021505172A/ja active Pending
- 2018-12-06 SG SG11202004913TA patent/SG11202004913TA/en unknown
- 2018-12-06 AU AU2018378804A patent/AU2018378804B2/en active Active
- 2018-12-06 CA CA3083783A patent/CA3083783A1/en active Pending
-
2020
- 2020-06-16 CO CONC2020/0007275A patent/CO2020007275A2/es unknown
- 2020-07-13 MX MX2024004652A patent/MX2024004652A/es unknown
-
2023
- 2023-11-02 JP JP2023188499A patent/JP2024023226A/ja active Pending
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