JP2021500882A5 - - Google Patents
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- Publication number
- JP2021500882A5 JP2021500882A5 JP2020521861A JP2020521861A JP2021500882A5 JP 2021500882 A5 JP2021500882 A5 JP 2021500882A5 JP 2020521861 A JP2020521861 A JP 2020521861A JP 2020521861 A JP2020521861 A JP 2020521861A JP 2021500882 A5 JP2021500882 A5 JP 2021500882A5
- Authority
- JP
- Japan
- Prior art keywords
- chimeric polypeptide
- region
- stalk
- polypeptide according
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023118889A JP2023153866A (ja) | 2017-10-18 | 2023-07-21 | スペーサーを含むポリペプチド組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762574061P | 2017-10-18 | 2017-10-18 | |
| US62/574,061 | 2017-10-18 | ||
| PCT/US2018/056334 WO2019079486A1 (en) | 2017-10-18 | 2018-10-17 | POLYPEPTIDE COMPOSITIONS COMPRISING SPACERS |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023118889A Division JP2023153866A (ja) | 2017-10-18 | 2023-07-21 | スペーサーを含むポリペプチド組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021500882A JP2021500882A (ja) | 2021-01-14 |
| JP2021500882A5 true JP2021500882A5 (https=) | 2021-11-25 |
Family
ID=66096807
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020521861A Pending JP2021500882A (ja) | 2017-10-18 | 2018-10-17 | スペーサーを含むポリペプチド組成物 |
| JP2023118889A Pending JP2023153866A (ja) | 2017-10-18 | 2023-07-21 | スペーサーを含むポリペプチド組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023118889A Pending JP2023153866A (ja) | 2017-10-18 | 2023-07-21 | スペーサーを含むポリペプチド組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11771718B2 (https=) |
| EP (1) | EP3697438A4 (https=) |
| JP (2) | JP2021500882A (https=) |
| KR (2) | KR102742741B1 (https=) |
| CN (1) | CN111511391B (https=) |
| AU (2) | AU2018352984B2 (https=) |
| CA (1) | CA3079264A1 (https=) |
| IL (2) | IL316522A (https=) |
| SG (1) | SG11202003543WA (https=) |
| WO (1) | WO2019079486A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3820484A4 (en) * | 2018-07-10 | 2022-05-04 | Precigen, Inc. | ROR-1 SPECIFIC CHIMERA ANTIGEN RECEPTORS AND USES THEREOF |
| JP7627080B2 (ja) * | 2018-08-31 | 2025-02-05 | シアトル チルドレンズ ホスピタル ディー／ビー／エイ シアトル チルドレンズ リサーチ インスティテュート | Ｂ７ｈ３キメラ抗原受容体を含む方法および組成物 |
| SG11202104287RA (en) * | 2018-11-06 | 2021-05-28 | Univ Washington | Chimeric antigen receptor memory-like (carml) nk cells and methods of making and using same |
| WO2020214937A1 (en) * | 2019-04-19 | 2020-10-22 | Allogene Therapeutics, Inc. | Antibodies against 4g7-derived chimeric antigen receptors |
| EP3962527A4 (en) | 2019-04-30 | 2023-11-01 | Senti Biosciences, Inc. | CHIMERIC RECEPTORS AND METHODS OF USE THEREOF |
| SE544015C2 (en) * | 2019-06-18 | 2021-11-02 | Tx Medic Ab | Allogenic car-t cell therapy |
| CN114222763A (zh) * | 2019-06-19 | 2022-03-22 | 尤利乌斯·马克西米利安维尔茨堡大学 | 在嵌合抗原受体设计中实现的超模块化IgG3间隔区结构域和多功能位点 |
| CN114761084B (zh) * | 2019-09-24 | 2023-10-27 | 加利福尼亚大学董事会 | 具有铰链结构域的Notch受体 |
| CN112111014A (zh) * | 2020-09-22 | 2020-12-22 | 廖文强 | 一种抗氧化嵌合型抗原受体和免疫细胞 |
| MX2023008115A (es) * | 2021-01-11 | 2023-09-11 | Precigen Inc | Terapia con receptores quiméricos. |
| US20240108653A1 (en) * | 2021-02-05 | 2024-04-04 | University Of Utah Research Foundation | Compositions and methods for treating with car cells |
| AU2022227686A1 (en) | 2021-02-25 | 2023-07-27 | Lyell Immunopharma, Inc. | Ror1 targeting chimeric antigen receptor |
| EP4334361A1 (en) | 2021-05-05 | 2024-03-13 | Immatics Biotechnologies GmbH | Antigen binding proteins specifically binding prame |
| TW202521564A (zh) * | 2023-08-14 | 2025-06-01 | 美商英特利亞醫療公司 | 用於基於細胞之療法的ｃｄ７０ ｃａｒ－ｔ組合物及方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3083324A1 (en) * | 2010-03-05 | 2011-09-09 | The Johns Hopkins University | Compositions and methods for targeted immunomodulatory antibodies and fusion proteins |
| ES2754394T3 (es) | 2010-09-08 | 2020-04-17 | Chemotherapeutisches Forschungsinstitut Georg Speyer Haus | Receptores de antígenos quiméricos con una región bisagra optimizada |
| WO2013059593A1 (en) | 2011-10-20 | 2013-04-25 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-cd22 chimeric antigen receptors |
| US20140370012A1 (en) * | 2012-01-27 | 2014-12-18 | Gliknik Inc. | Fusion proteins comprising igg2 hinge domains |
| CA2881981A1 (en) | 2012-08-20 | 2014-02-27 | Fred Hutchinson Cancer Research Center | Method and compositions for cellular immunotherapy |
| EP3783098A1 (en) | 2013-05-14 | 2021-02-24 | Board Of Regents, The University Of Texas System | Human application of engineered chimeric antigen receptor (car) t-cells |
| US10287354B2 (en) | 2013-12-20 | 2019-05-14 | Novartis Ag | Regulatable chimeric antigen receptor |
| CN113354744A (zh) | 2013-12-20 | 2021-09-07 | 弗雷德哈钦森癌症研究中心 | 带标签的嵌合效应分子及其受体 |
| EP3656864A1 (en) * | 2014-02-14 | 2020-05-27 | Board of Regents, The University of Texas System | Chimeric antigen receptors and methods of making |
| JP6556156B2 (ja) * | 2014-02-27 | 2019-08-07 | ユーシーエル ビジネス ピーエルシー | Ａｐｒｉｌバリアント |
| CA2945320A1 (en) | 2014-04-10 | 2015-10-15 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Drug regulated transgene expression |
| SI3194434T1 (sl) | 2014-09-15 | 2019-11-29 | Molmed Spa | Himerni antigenski receptorji |
| JP2017531430A (ja) * | 2014-10-07 | 2017-10-26 | セレクティスＣｅｌｌｅｃｔｉｓ | Ｃａｒによって誘導される免疫細胞の活性を調節するための方法 |
| WO2016168769A1 (en) | 2015-04-15 | 2016-10-20 | The California Institute For Biomedical Research | Chimeric receptor t cell switches for her2 |
| EP4424326A3 (en) * | 2015-06-10 | 2024-11-13 | ImmunityBio, Inc. | Modified nk-92 cells for treating cancer |
| WO2016210447A1 (en) | 2015-06-26 | 2016-12-29 | University Of Southern California | Masking chimeric antigen receptor t cells for tumor-specific activation |
| WO2017027291A1 (en) | 2015-08-07 | 2017-02-16 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Bispecific car t-cells for solid tumor targeting |
| EP3708587B1 (en) * | 2015-11-27 | 2024-05-22 | Cartherics Pty. Ltd. | Genetically modified cells and uses thereof |
| MA45341A (fr) | 2016-06-06 | 2019-04-10 | Hutchinson Fred Cancer Res | Procédés de traitement de malignités de lymphocytes b au moyen d'une thérapie cellulaire adoptive |
| SG11201810640RA (en) * | 2016-06-08 | 2018-12-28 | Intrexon Corp | Cd33 specific chimeric antigen receptors |
| KR20190102259A (ko) * | 2017-01-10 | 2019-09-03 | 인트렉손 코포레이션 | 신규의 유전자 스위치 발현 시스템을 통한 폴리펩티드의 발현 조절 |
| EP3635132A4 (en) * | 2017-06-07 | 2021-05-26 | Intrexon Corporation | EXPRESSION OF NOVEL CELL MARKERS |
| US11319380B2 (en) * | 2018-06-04 | 2022-05-03 | Precigen, Inc. | MUC16 specific chimeric antigen receptors and uses thereof |
| WO2020014285A2 (en) * | 2018-07-09 | 2020-01-16 | Intrexon Corporation | Fusion constructs and methods of using thereof |
| EP3820484A4 (en) * | 2018-07-10 | 2022-05-04 | Precigen, Inc. | ROR-1 SPECIFIC CHIMERA ANTIGEN RECEPTORS AND USES THEREOF |
| EP4178680A4 (en) * | 2020-07-10 | 2024-07-31 | Precigen, Inc. | FUSION CONSTRUCTS AND THEIR METHODS OF USE |
| MX2023008115A (es) * | 2021-01-11 | 2023-09-11 | Precigen Inc | Terapia con receptores quiméricos. |
-
2018
- 2018-10-17 EP EP18869303.0A patent/EP3697438A4/en active Pending
- 2018-10-17 SG SG11202003543WA patent/SG11202003543WA/en unknown
- 2018-10-17 AU AU2018352984A patent/AU2018352984B2/en active Active
- 2018-10-17 CA CA3079264A patent/CA3079264A1/en active Pending
- 2018-10-17 IL IL316522A patent/IL316522A/en unknown
- 2018-10-17 KR KR1020207013590A patent/KR102742741B1/ko active Active
- 2018-10-17 WO PCT/US2018/056334 patent/WO2019079486A1/en not_active Ceased
- 2018-10-17 IL IL273961A patent/IL273961B2/en unknown
- 2018-10-17 KR KR1020247040963A patent/KR20250010043A/ko active Pending
- 2018-10-17 CN CN201880082078.9A patent/CN111511391B/zh active Active
- 2018-10-17 JP JP2020521861A patent/JP2021500882A/ja active Pending
- 2018-10-17 US US16/163,233 patent/US11771718B2/en active Active
-
2023
- 2023-06-29 US US18/344,421 patent/US20230414661A1/en active Pending
- 2023-07-21 JP JP2023118889A patent/JP2023153866A/ja active Pending
- 2023-12-13 AU AU2023282226A patent/AU2023282226B2/en active Active
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