JP2021161077A - Aqueous cosmetic - Google Patents

Abstract

To provide a cosmetic having no squeaky feeling at the time of application and an effect of inhibiting aggregation of a powder while containing a white pigment in order to exhibit an instantaneous whitening effect.SOLUTION: There is provided an aqueous cosmetic which comprises the following components (A) to (D): (A) 1 to 10 mass% of niacinamide, (B) 0.5 to 10 mass% of tranexamic acid, (C) a nonionic surfactant having a polyoxyethylene chain and (D) a white pigment.SELECTED DRAWING: None

Description

The present invention relates to a water-based cosmetic, and more particularly to a water-based cosmetic which contains powder but does not have a squeaky feeling at the time of use and is excellent in suppressing the aggregation of powder.

Maintaining healthy and beautiful skin is a matter of great concern to many. The skin causes various problems such as rough skin, wrinkles, sagging, and pigmentation due to various factors such as ultraviolet rays, dryness, aging, and stress. In order to improve these skin problems from various aspects, it is considered effective to act on the skin with a plurality of components having different actions.
For example, niacinamide is one of the vitamins, but has effects on the skin such as wrinkle improving effect, skin barrier ability improving, whitening effect, and skin texture improving effect (Non-Patent Document 1). Since tranexamic acid has an anti-inflammatory effect, it is known to be used as an active ingredient of a pharmaceutical product and to have an effect of suppressing melanin production (Patent Document 1). A composition containing these two components having different actions is expected to bring about a multifaceted effect on a plurality of skin problems.

On the other hand, cosmetics containing these active ingredients gradually show an improving effect after long-term continuous use, and it has been difficult to feel an immediate effect immediately after applying the cosmetic, but in recent years For example, the formulation of a white pigment powder such as titanium oxide has been studied for the purpose of producing an immediate whitening effect after application.

Japanese Unexamined Patent Publication No. 2008-100933

Cosmeceuticals and Cosmetic practice Chap.10.2014 page 103-112

However, in skin care cosmetics, when powder is blended, a squeaky or dry feeling occurs during or after application, so that the feeling of use may be inferior, or the powder may aggregate or settle, resulting in stability. There was also a problem in terms of.
Therefore, it is an object of the present invention to develop a cosmetic which contains white pigment powder in order to produce an immediate whitening effect, does not have a squeaky feeling at the time of application, and has an excellent effect of suppressing powder aggregation.

Therefore, as a result of diligent research to solve the above problems, the present inventor has conducted nonionic surfactants having niacinamide, tranexamic acid, and polyoxyethylene chains in an aqueous cosmetic containing white pigment powder. The present invention has been completed by finding that the squeaky feeling and aggregation peculiar to powder are suppressed by using the agents in combination.

That is, in the present invention, the following components (A) to (D):
(A) Niacinamide 1-10% by mass
(B) Tranexamic acid 0.5-10% by mass
(C) An aqueous cosmetic containing a nonionic surfactant (D) white pigment having a polyoxyethylene chain.

According to the present invention, it is possible to suppress the squeaky feeling and pigment aggregation at the time of application derived from the white pigment. Therefore, it can produce an immediate whitening effect as a cosmetic, and it can be used continuously for a long period of time because it has excellent usability and stability. It also has an excellent skin effect as an active ingredient of niacinamide and tranexamic acid. Can be provided.

Hereinafter, the present invention will be described in detail. In addition, in this specification, "~" means the range including the numerical values before and after it. The component (A) niacinamide used in the present invention is an amide compound of nicotinic acid (vitamin B3 / niacin). Niacinamide is a water-soluble vitamin, which is a known substance belonging to the B vitamin group, and can be extracted from a natural product (rice bran, etc.) or synthesized by a known method. Specifically, those listed in the 17th revised Japanese Pharmacopoeia can be used.

The content of the component (A) in the present invention is 1 to 10% by mass (hereinafter, simply abbreviated as "%"), preferably 3 to 10%, and particularly preferably 4 to 9%. If the content of the component (A) is less than 1%, a firmness or the like may not be obtained, and if it exceeds 10%, a sticky feeling at the time of application may be strong and a feeling of use may be poor.

The component (B) tranexamic acid used in the present invention is a kind of amino acid represented by trans-4- (aminomethyl) cyclohexane-1-carboxylic acid. Tranexamic acid may be used as a whitening effect or anti-inflammatory effect on the skin, and may also be used as a hemostatic agent.

The content of the component (B) in the present invention is 0.5 to 10% by mass, preferably 1 to 8%, and particularly preferably 1 to 5%. If the content of the component (A) is less than 0.5%, a whitening effect or the like may not be obtained, and if it exceeds 10%, a sticky feeling at the time of application may be strong and a feeling of use may be poor.

The nonionic surfactant having the component (C) polyoxyethylene chain used in the present invention may be any one having a polyoxyethylene chain as a hydrophilic group, and has a glycerin skeleton as a hydrophilic group other than the polyoxyethylene chain. , A sorbitan skeleton, a sorbit skeleton and the like may be provided, and examples of the lipophilic group include a polymer having a fatty acid skeleton and a siloxane skeleton. Specifically, as the component (C), coconut oil fatty acid polyoxyethylene glyceryl, polyoxyethylene glyceryl laurate, polyoxyethylene glyceryl oleate, polyoxyethylene glyceryl stearate, polyoxyethylene glyceryl isostearate, polytristearate Fatty acid polyoxyethylene glyceryl such as oxyethylene glyceryl, polyoxyethylene glyceryl diisostearate, polyoxyethylene glyceryl triisostearate, polyoxyethylene glyceryl trioleate, coconut oil fatty acid polyoxyethylene sorbitan, polyoxyethylene sorbitan monooleate , Polyoxyethylene sorbitan trioleate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan tristearate, polyoxyethylene sorbitan monoisostearate and other fatty acids polyoxyethylene sorbitans, polyoxyethylene sorbit monolaurate, tetrasteare Examples thereof include fatty acid polyoxyethylene sorbits such as acid polyoxyethylene sorbit and polyoxyethylene sorbit tetraoleate. These can be used alone or in combination of two or more. Among these, fatty acid polyoxyethylene sorbitans are preferable for suppressing aggregation and precipitation of titanium oxide, and polyoxyethylene sorbitan monooleate is particularly preferable.

Further, as the component (C), those having an HLB value of 10 to 18 are preferable, and those having an HLB value of 11 to 16 are more preferable. The HLB (hydrophilic-lipophilic balance) value referred to here refers to a value obtained by the Griffin method.

The content of the component (C) in the present invention is not particularly limited, but is preferably 0.01 to 3%, more preferably 0.03 to 2%, and even more preferably 0.05 to 1%. When the content of the component (C) is in this range, the effect of suppressing the aggregation of the component (D) is excellent, and the sticky feeling at the time of application is small, which is preferable.

The component (D) white pigment used in the present invention colors cosmetics and gives a covering power at the time of application, and can be used without particular limitation as long as it is an inorganic pigment generally used in cosmetics. , These may be in the form of composite powder. Specific examples of the component (D) include mica, talc, titanium oxide, zinc oxide and the like, and these can be used by coating them with powder such as glass flakes and aluminum. For example, titanium oxide can be used. Examples thereof include a composite powder of coated mica, titanium oxide-coated bismuth oxychloride, fine particle titanium oxide-coated mica titanium, and titanium oxide-containing silicon dioxide. These can be used alone or in combination of two or more, but titanium oxide and its composite powder are preferable in that a more natural whitening effect is produced.

Further, the component (D) is known by using a silicone compound, a fluorine compound, a metal soap, collagen, a hydrocarbon, a higher fatty acid, a lecithin, a higher alcohol, an ester, a wax, a wax, a surfactant and the like, if necessary. A surface-treated product may be used according to the above method. From the viewpoint of suppressing pigment aggregation, those subjected to surface treatment with a hydrophobic compound are preferable.

The shape of the component (D) may be, for example, plate-shaped, granular, spherical, spindle-shaped, dendritic or the like. The average particle size of the component (D) is preferably 1 nm to 100 μm, more preferably 5 nm to 30 μm, but 0.15 to 0.3 μm in terms of producing a more natural whitening effect. So-called pigment grade ones are preferable.

The blending amount of the component (D) in the present invention is not particularly limited, but is preferably 0.1 to 3%, more preferably 0.5 to 2%. Within this range, there is no squeaky feeling at the time of application, and a more natural whitening effect can be produced, which is preferable.

In addition to the above components (A) to (D), the aqueous cosmetic of the present invention may appropriately contain components used in ordinary skin external preparations as long as the effects of the present invention are not impaired. For example, oils such as higher alcohols, hydrocarbon oils, ester oils, waxes, silicone oils, surfactants other than component (C), water-soluble polymers, polyhydric alcohols, lower alcohols and other aqueous components, components (D). ), Ultraviolet absorbers, antioxidants, antibacterial agents, preservatives, moisturizers, pH regulators, refreshing agents, vitamins, beauty ingredients, fragrances and the like can be contained.

The aqueous cosmetic of the present invention is a cosmetic having an aqueous component as a continuous phase in the outer phase, and can be implemented in various forms such as liquid, gel, and cream, and the dosage form is soluble. -Dispersion type, solubilization type, oil-in-water emulsification type, water-in-water type, multi-layer type, etc. are not particularly limited.

The method for producing the aqueous cosmetic product of the present invention is not particularly limited, and is prepared by a conventional method.

The pH of the aqueous cosmetic of the present invention is not particularly limited, but the pH at 25 ° C. is preferably in the range of 4.0 to 8.5 in terms of the stability of the components (A) and (B). ..

The aqueous cosmetics of the present invention include, for example, lotions, milky lotions, creams, beauty essences, massage agents, packs, hand creams, body lotions, body creams, sunscreens, foundations, eye shadows, eyeliners, and concealers. , Treatment for scalp and the like can be exemplified. Skin care cosmetics are preferable in that the effect can be felt, and the methods of use include a method of using with hands, fingers, and cotton, a method of impregnating with a non-woven fabric, and a method of directly spraying. ..

Hereinafter, examples will be given to specifically explain the present invention, but the present invention is not limited to these examples and the like. Further, unless otherwise specified, the content is shown in mass% with respect to the cosmetic containing the component.

Examples 1 to 5 and Comparative Examples 1 to 3: Beauty essences The beauty essences having the compositions shown in Table 1 are produced by the following production methods, and a: agglutination inhibitory effect and b: no squeaky feeling are shown below. The evaluation was made by. The results are also shown in Table 1.

(Production method)
A: A part of the components (3) to (5) and (7) is mixed.
B: The balance of the components (1), (2), (6) and the component (7) was uniformly heated and solved at 75 ° C.
C: A was added to B at 75 ° C. and stirred to obtain a beauty essence.

(Evaluation method 1)
(B. Agglutination suppression)
Regarding the suppression of agglutination, the samples of Examples 1 to 5 and Comparative Examples 1 to 3 were evaluated by the transparency when diluted 10-fold with water. It has been confirmed that the transparency can ensure long-term stability.
After storing the sample in a constant temperature bath at 40 ° C. for 1 month, 1.0 g of each sample was weighed in a glass beaker, diluted 10-fold with purified water, and stirred until a uniform solution was obtained. At that time, the mixture was stirred by hand using a metal ointment spatula. The obtained material was filled in a glass cell having an optical path length of 10 mm and an optical path width of 5 mm, and the transmittance at a wavelength of 700 nm was measured with a spectrophotometer (UV-2500PC, manufactured by SHIMADZU).
<Criteria>
(Judgment): (Evaluation)
◎: Transmittance is 55% or more (no agglutination)
Δ: Transmittance is 45 to 55% (some agglutination is seen)
X: Transmittance is less than 45% (clearly there are agglomerates)

(Evaluation method 2)
(B: No squeaky feeling)
Women in their 20s to 40s were trained in sensory evaluation, and 10 specialized panels that could be evaluated according to certain criteria were selected. Each sample was used for the forearm of the specialized panel, and the permeation feeling, non-stickiness, and firmness of the back skin felt at the time of use were evaluated and scored on a 5-point scale by the following absolute evaluation. The average value was calculated from the total score of all the panels for each sample, and the judgment was made according to the following four-step judgment criteria.
<Absolute evaluation criteria>
(Score): (Evaluation)
5 points: No squeaky feeling 4 points: I don't care about squeaky feeling 3 points: Neither 2 points: I'm a little worried about squeaky feeling 1 point: I'm quite worried about squeaky feeling <4 grade criteria> (The same applies to the following evaluation items)
(Judgment): (Average score)
◎: More than 4.5 points: Very good ○: More than 3.5 points and less than 4.5 points: Good △: More than 1.5 points and less than 3.5 points: Slightly poor ×: More than 1.5 points : Bad

As is clear from the results in Table 1, the beauty essences of Examples 1 to 5 were superior to the beauty essences of Comparative Examples 1 to 3 in terms of suppressing aggregation and lacking squeaky feeling.

Example 6: Toner (ingredient) (%)
(1) Alkyltrimethylammonium chloride 0.1
(2) Hydrogenated soybean phospholipid 0.5
(3) 1,3-butylene glycol 5.0
(4) Polyoxyethylene sorbitan monooleate (20EO) 1.0
(5) Appropriate amount of fragrance (6) Ethanol 10.0
(7) Preservatives Appropriate amount (8) Niacinamide 5.0
(9) Tranexamic acid 2.0
(10) Polyoxyethylene glycerin (26EO) 2.0
(11) Zinc oxide 2.0
(12) (Acrylate / Alkyl Acrylate (C10-30))
Cross polymer 0.1
(13) Carboxyvinyl polymer 0.1
(14) Sodium hydroxide 0.05
(15) Remaining amount of purified water

(Production method)
A: The components (1) to (3) are uniformly dissolved and mixed at 75 ° C.
B: A part of the component (15) is added while maintaining the A at 75 ° C., and the mixture is stirred with a dispa mixer to obtain a vesicle dispersion.
C: The components (4) to (14) and the rest of the component (15) are uniformly dissolved and mixed at room temperature.
D: Toner was obtained by adding and mixing the B cooled to 35 ° C. to the C.
The lotion obtained as described above was excellent in suppressing aggregation and lacking a squeaky feeling.

Example 7: Toner (ingredient) (%)
(1) Polyoxyethylene isostearate (50) Hardened castor oil 0.2
(2) PEG-10 methyl ether dimethicone 0.1
(3) Ethyl oleate 0.05
(4) Cetyl 2-ethylhexanoate 0.05
(5) Titanium oxide 0.1
(6) Ethanol 1.0
(7) 1,3-butylene glycol 5.0
(8) Glycerin 5.0
(9) Diglycerin 2.0
(10) Polyoxybutylene polyoxyethylene polyoxypropylene glyceryl ether (3EO) 3.0
(11) Niacinamide 5.0
(12) Carboxyvinyl polymer 0.1
(13) Sodium hydroxide 0.05
(14) Tranexamic acid 1.0
(15) Sodium metabisulfite 0.003
(16) Appropriate amount of fragrance (17) Remaining amount of purified water

(Production method)
A: Ingredients (1) to (5) are mixed at 70 ° C.
B: Ingredients (11) to (17) are uniformly dissolved and mixed at room temperature.
C: The above A was added to B and solubilized at room temperature to obtain a lotion.
The lotion obtained as described above was excellent in agglutination suppression and a squeaky feeling.

Example 8: Oil-in-water emulsified beauty essence (ingredient) (%)
(1) (Icosanedioic acid / tetradecanedioic acid) Polyglyceryl-10 1.5
(2) Tripropylene glycol 15.0
(3) Niacinamide 6.0
(4) L-Theanine 0.05
(5) 1,3-butylene glycol 3.5
(6) Dipropylene glycol 0.5
(7) Remaining amount of purified water (8) Glycerin 2.0
(9) Polyethylene glycol 2.0
(10) Tranexamic acid 2.0
(11) Sodium hydrogen phosphate 0.3
(12) Sodium dihydrogen phosphate 0.6
(13) Sodium disetate 0.02
(14) Sodium metabisulfite 0.005
(15) Polyoxyethylene isostearate (50) Hardened castor oil 0.2
(16) Polyoxyethylene (60) hardened castor oil 0.2
(17) Dicocoyl ethyl hydroxyethylmonium metosulfate 0.01
(18) Ethanol 5.0
(19) L-menthol 0.02
(20) Isopropyl myristate 0.3
(21) Dimer dilinoleic acid (phytosteryl / isostearyl / cetyl /
Stearyl / behenyl) 0.2
(22) Sorbitan oleate 0.2
(23) Tocotrienols 0.02
(24) Carboxyvinyl polymer 0.02
(25) (Acrylate / Alkyl Acrylate (C10-30))
Cross polymer 0.02
(26) Xanthan gum 0.01
(27) Sodium hydroxide 0.01
(28) Titanium oxide coated mica 0.5

(Production method)
A: Ingredients (1) to (14) are uniformly mixed at room temperature.
B: Ingredients (15) to (23) are uniformly dissolved and mixed at 70 ° C.
C: B is added to A and emulsified at 70 ° C.
D: After cooling the C to 40 ° C., components (24) to (28) were added and mixed uniformly to obtain a beauty essence.
The oil-in-water emulsified beauty essence obtained as described above was excellent in suppressing aggregation and lacking a squeaky feeling.

Example 9: Sunscreen (underwater oil type)
(Ingredient) (%)
(1) 1,3-butylene glycol 5.0
(2) Dipropylene glycol 5.0
(3) 1,2-Pentanediol 0.1
(4) Hydrogenated lecithin (Note 2) 0.5
(5) Cholesterol 0.6
(6) Phytosterol 0.1
(7) Remaining amount of purified water (8) Niacinamide 3.0
(9) Tranexamic acid 2.0
(10) (Acrylic acid / Alkyl acrylate (C10-30))
Cross polymer 0.4
(11) Triethanolamine 0.4
(12) Dimethicodiethylbenzalmalonate 1.2
(13) 4-tert-Butyl-4'-methoxy-dibenzoylmethane 2.0
(14) 2-Ethylhexyl paramethoxycinnamate 7.0
(15) Diethylaminohydroxybenzoyl hexyl benzoate 2.5
(16) Stearic acid hardened castor oil 1.0
(17) Propylene glycol dicaprate 5.0
(18) Ethyl oleate 0.3
(19) Natural Vitamin E 0.1
(20) Rosemary oil 0.01
(21) Titanium oxide 1.0
(22) Zinc oxide 2.0
(23) Water-soluble collagen 0.01
(24) Chamomile flower extract 0.05
(25) Calendula officinalis flower extract 0.05
(26) Glycerin 1.0
(27) Ethanol 7.0
(28) Fragrance 0.1
(Note 2) Nikkor Resinol S-10 (manufactured by Nikko Chemicals Co., Ltd.)

(Production method)
A: The components (1) to (6) are uniformly dissolved and mixed at 75 ° C.
B: Ingredients (7) to (11) are uniformly dissolved and mixed at 70 ° C.
C: Ingredients (12) to (19) are uniformly dissolved and mixed at 80 ° C.
D: B and C are added to A and emulsified at 70 ° C.
E: Ingredients (20) to (28) were added to and mixed with D, and then cooled to 40 ° C. to obtain a sunscreen (oil-in-water type).
The sunscreen (oil-in-water type) obtained as described above was excellent in suppressing aggregation and lacking a squeaky feeling.

Example 10: Oil-in-water emulsion (ingredient) (%)
(1) 1,3-butylene glycol 5.0
(2) Dipropylene glycol 5.0
(3) Titanium oxide 0.03
(4) Hydrogenated soybean phospholipid 0.2
(5) Cholesterol 0.7
(6) Remaining amount of purified water (7) Niacinamide 8.0
(8) Sodium hydroxide 2% aqueous solution 0.2
(9) N-myristoyl-L-glutamic acid 0.2
(10) Polyoxyethylene (10) Hardened castor oil 0.2
(11) Macadamia nut oil fatty acid phytosteryl 1.0
(12) Tri (caprylic acid / caprylic acid) glyceryl 0.2
(13) Tocopherol nicotinic acid ester 0.01
(14) Natural Vitamin E 0.1
(15) Rice germ oil 0.01
(16) Tocopherol acetate 0.01
(17) Polyoxyethylene sorbitan monooleate (20EO) 1.5
(18) Stearyl alcohol 0.5
(19) Behenyl alcohol 1.0
(20) 1,2-Pentanediol 0.1
(21) Stearyl alcohol 0.5
(22) Carboxyvinyl polymer 0.2
(23) (Na acrylate / Na acryloyldimethyltaurine)
Copolymer mixture (Note 3) 0.5
(24) Tranexamic acid 1.0
(25) Diglycerin 0.5
(26) Titanium oxide 1.0
(27) Silica 0.05
(28) Black soybean extract 0.05
(29) Sesame germinated body extract 0.05
(30) Glycerin 1.0
(31) Ethanol 5.0
(32) Fragrance 0.1
(Note 3) SIMULGEL EG QD (manufactured by SEPPIC)

(Production method)
A: Ingredients (1) to (5) are uniformly dissolved and mixed at 75 ° C.
B: A part of the component (6) is added while maintaining the A at 75 ° C., and the mixture is stirred with a dispa mixer to obtain a vesicle dispersion.
C: The remaining components (6) to (8) are uniformly dissolved and mixed at room temperature.
D: Ingredients (9) to (19) are uniformly dissolved and mixed at 80 ° C.
E: The C heated while maintaining the D at 75 ° C. is added and emulsified.
F: Ingredients (20) to (32) were added to and mixed with E, and then cooled to 40 ° C. to obtain an oil-in-water emulsion.
The oil-in-water emulsion obtained as described above was excellent in suppressing aggregation and lacking a squeaky feeling.

Claims (2)

The following components (A) to (D):
(A) Niacinamide 1-10% by mass
(B) Tranexamic acid 0.5-10% by mass
(C) A nonionic surfactant having a polyoxyethylene chain (D) An aqueous cosmetic containing a white pigment. The aqueous cosmetic according to claim 1, wherein the component (D) is one or more selected from titanium oxide, zinc oxide, talc, and mica.