JP2021119164A5 - - Google Patents
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- Publication number
- JP2021119164A5 JP2021119164A5 JP2021074407A JP2021074407A JP2021119164A5 JP 2021119164 A5 JP2021119164 A5 JP 2021119164A5 JP 2021074407 A JP2021074407 A JP 2021074407A JP 2021074407 A JP2021074407 A JP 2021074407A JP 2021119164 A5 JP2021119164 A5 JP 2021119164A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- buffer solution
- compound
- mannitol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 32
- 239000007853 buffer solution Substances 0.000 claims 10
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 9
- 150000001875 compounds Chemical class 0.000 claims 5
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical group OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 4
- 229930195725 Mannitol Natural products 0.000 claims 4
- 239000000594 mannitol Substances 0.000 claims 4
- 235000010355 mannitol Nutrition 0.000 claims 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims 3
- 229940125782 compound 2 Drugs 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
- 239000001509 sodium citrate Substances 0.000 claims 2
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims 2
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims 1
- LJHFUFVRZNYVMK-CYBMUJFWSA-N [3-[4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxyphenyl]-[(3R)-3-hydroxypyrrolidin-1-yl]methanone Chemical compound NCC1=CC(=NC(=C1)C(F)(F)F)OC=1C=C(C=CC=1)C(=O)N1C[C@@H](CC1)O LJHFUFVRZNYVMK-CYBMUJFWSA-N 0.000 claims 1
- 239000008351 acetate buffer Substances 0.000 claims 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims 1
- 229910052782 aluminium Inorganic materials 0.000 claims 1
- 239000000872 buffer Substances 0.000 claims 1
- 239000011888 foil Substances 0.000 claims 1
- 239000004310 lactic acid Substances 0.000 claims 1
- 235000014655 lactic acid Nutrition 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000001384 succinic acid Substances 0.000 claims 1
- 239000011975 tartaric acid Substances 0.000 claims 1
- 235000002906 tartaric acid Nutrition 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562183403P | 2015-06-23 | 2015-06-23 | |
| US62/183,403 | 2015-06-23 | ||
| US201562268666P | 2015-12-17 | 2015-12-17 | |
| US62/268,666 | 2015-12-17 | ||
| JP2017566743A JP6876631B2 (ja) | 2015-06-23 | 2016-06-22 | 白金化合物、組成物及びその使用 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017566743A Division JP6876631B2 (ja) | 2015-06-23 | 2016-06-22 | 白金化合物、組成物及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021119164A JP2021119164A (ja) | 2021-08-12 |
| JP2021119164A5 true JP2021119164A5 (enExample) | 2021-09-24 |
| JP7223053B2 JP7223053B2 (ja) | 2023-02-15 |
Family
ID=57586683
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017566743A Expired - Fee Related JP6876631B2 (ja) | 2015-06-23 | 2016-06-22 | 白金化合物、組成物及びその使用 |
| JP2021074407A Active JP7223053B2 (ja) | 2015-06-23 | 2021-04-26 | 白金化合物、組成物及びその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017566743A Expired - Fee Related JP6876631B2 (ja) | 2015-06-23 | 2016-06-22 | 白金化合物、組成物及びその使用 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US10342801B2 (enExample) |
| EP (1) | EP3313392B1 (enExample) |
| JP (2) | JP6876631B2 (enExample) |
| WO (1) | WO2016209918A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE056897T2 (hu) | 2015-12-09 | 2022-03-28 | Univ Wien Med | Monomaleimid-funkcionalizált platinavegyületek rákterápiához |
| CA3062369A1 (en) | 2017-05-05 | 2018-11-08 | Intezyne Technologies, Inc. | Manufacture of trans-[tetrachlorobis(1h-indazole)ruthenate (iii)] and compositions thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008001101A2 (en) * | 2006-06-29 | 2008-01-03 | Astex Therapeutics Limited | Pharmaceutical combinations |
| US9090640B2 (en) * | 2011-09-02 | 2015-07-28 | Ulrich Bierbach | Targeted delivery and prodrug designs for platinum-acridine anti-cancer compounds and methods thereof |
| WO2014100417A1 (en) * | 2012-12-19 | 2014-06-26 | Blend Therapeutics, Inc. | Compounds, compositions, and methods for the treatment of cancers |
| WO2015102922A1 (en) * | 2013-12-31 | 2015-07-09 | Blend Therapeutics, Inc. | Compounds, compositions, and methods for the treatment of cancers |
| EP3797768A1 (en) * | 2014-06-23 | 2021-03-31 | Placon Therapeutics, Inc. | Maleimide-functionalised platinum for use in the treatment of cancer |
-
2016
- 2016-06-22 US US15/737,064 patent/US10342801B2/en active Active
- 2016-06-22 WO PCT/US2016/038699 patent/WO2016209918A1/en not_active Ceased
- 2016-06-22 JP JP2017566743A patent/JP6876631B2/ja not_active Expired - Fee Related
- 2016-06-22 EP EP16815194.2A patent/EP3313392B1/en not_active Not-in-force
-
2019
- 2019-05-16 US US16/413,719 patent/US20190350940A1/en not_active Abandoned
-
2021
- 2021-04-26 JP JP2021074407A patent/JP7223053B2/ja active Active
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