JP2021080230A - Topical skin preparation - Google Patents

Abstract

To provide a topical skin preparation that reduces a sticky touch caused by a hydrophilic polymer and has an improved use feeling.SOLUTION: A topical skin preparation contains one or more hydrophilic polymer selected from an acrylic polymer, a urethane polymer and a polysaccharide polymer, and solid spherical borosilicate particles.SELECTED DRAWING: None

Description

The present invention relates to an external preparation for skin such as a cosmetic, and more particularly to an external preparation for skin that is not sticky and has a good usability.

In cosmetics, quasi-drugs, and external preparations for skin such as pharmaceuticals, hydrophilic polymers are blended for the purpose of maintaining product stability. (See Patent Documents 1 to 6)

However, while hydrophilic polymers have an excellent effect of improving stability, they tend to be sticky to the touch, so formulations containing hydrophilic polymers are often disliked by consumers. It has been a big difficulty in blending with external skin preparations, especially cosmetics.

Further, it has been known that solid glass is blended in cosmetics (see Patent Document 7), but it has not been known that blending solid glass reduces stickiness due to a hydrophilic polymer. ..

Japanese Unexamined Patent Publication No. 2017-197490 JP-A-2017-128524 International release WO2017 / 006488 International release WO2017-006488 International release WO2016 / 002752 Japanese Unexamined Patent Publication No. 2015-151392 Japanese Unexamined Patent Publication No. 6-321726

An object of the present invention is to provide an external preparation for skin that is not sticky due to a hydrophilic polymer and has a good usability.

As a result of diligent studies on such a problem, the present inventors have completed the present invention. That is, the present invention is as follows.
(1)
An external preparation for skin, which contains one or more hydrophilic polymers selected from an acrylic polymer, a urethane polymer, and a polysaccharide polymer, and solid spherical borosilicate particles. ..
(2)
The skin external preparation according to (1), wherein the solid spherical borosilicate particles are fine particle zinc oxide-coated solid spherical borosilicate particles.

The external preparation for skin of the present invention exhibits the effect that it is not sticky due to the hydrophilic polymer and has a good usability.

Hereinafter, embodiments for carrying out the present invention will be described in detail. However, the present invention is not limited to the following embodiments.

The external preparation for skin of the present invention contains one or more hydrophilic polymers selected from acrylic polymers, urethane polymers and polysaccharide polymers.

The acrylic acid-based polymer has an acrylic group structure and is not particularly limited as long as it can be used as a cosmetic. For example, (Acrylate / alkyl acrylate (C10-30)) crosspolymer, carbomer, (Na acrylate / acryloyldimethyltaurine / dimethylacrylamide) crosspolymer, acrylamide-2-methylpropanesulfonate copolymer, hydroxyacrylate. Ethyl / acryloyldimethyltaurine salt copolymer, acrylate / acryloyldimethyltaurin copolymer, acrylic acid amide / acrylic acid-2-methylpropanesulfonate copolymer, acryloyldimethyltaurine salt / vinylpyrrolidone copolymer, etc. Can be mentioned.
(Acrylate / Alkyl Acrylate (C10-30)) Commercial examples of cross-polymers include PEMULEN TR-1, PEMULEN TR-2, Carbopole 1342, Carbopole ETD2020, Carbopole ULTREZ-20, and Carbo manufactured by Lubrizol. Examples thereof include Paul ULTREZ-22, AQUAPEC HV-501ER manufactured by Sumitomo Seika Chemical Co., Ltd., AQUAPEC HV-701EDR, AQUAPEC HV-801ERK, AQUAPEC HV-803ERK, AQUAPEC SW-703ER, and AQUAPEC SR-705ER.
Examples of commercially available carbomer include Carbopole 934, Carbopole 940, Carbopole 941, Carbopole ETD2050 manufactured by Lubrizol, AQPEC HV-501E, AQPEC HV-505E, AQPEC HV-505ED, and AQPEC manufactured by Sumitomo Seika Chemical Co., Ltd. Examples thereof include HV-801EG-300, AQUAPEC HV-805EG-300, Hibiswaco 103, Hibiswaco 104 and Hibiswaco 105 manufactured by Wako Junyaku Co., Ltd.
(Na acrylate / acryloyldimethyltaurine / dimethylacrylamide) Crosspolymer, acrylamide-2-methylpropanesulfonate copolymer, hydroxyethyl acrylate / acryloyldimethyltaurine salt copolymer, acrylate / acryloyldimethyltaurine copolymer Commercially available examples of the coalesced polymer, acrylate / acrylate-2-methylpropanesulfonate copolymer, and acryloyldimethyltaurine salt / vinylpyrrolidone copolymer include SIMULGEL series and SEPINOV series manufactured by SEPIC.

The urethane-based polymer is not particularly limited as long as it is a water-soluble urethane-based polymer that can be blended with an external preparation for skin. As the urethane-based polymer, a hydrophobically modified polyether urethane is preferably used. Examples of the hydrophobically modified polyether urethane include polyethylene glycol (PEG) -240 / decyltetradeceth-20 / hexamethylene diisocyanate (HDI) copolymer. As a commercially available product of this PEG-240 / decyltetradeceth-20 / HDI copolymer, ADEKA's Adecanol GT-700 can be exemplified.

The polysaccharide polymer is not particularly limited as long as it is a water-soluble polysaccharide polymer that can be blended with an external preparation for skin. Examples of the polysaccharide-based polymer include alginate-based thickeners such as sodium alginate and propylene glycol alginate, hydroxypropylmethyl cellulose, hydroxypropyl cellulose, hydroxyethyl cellulose, carboxymethyl cellulose, methyl cellulose, cetyl hydroxyethyl cellulose, methyl hydroxyethyl cellulose, and hydroxyethyl ethyl cellulose. , Cellulose thickeners such as methyl hydroxypropyl cellulose and carboxymethyl hydroxyethyl cellulose, starch thickeners such as carboxymethyl starch and methyl hydroxypropyl starch, guar gum, Arabic gum, Karaya gum, gellan gum, agar, carrageenan, pectin, carboxy Examples thereof include methyl chitosan, purulan, hydroxyethyl chitosan, carboxymethyl dextran, corn starch, and dextrin.

The blending amount of the hydrophilic polymer is preferably 0.0001% by mass or more, more preferably 0.001% by mass or more, preferably 3% by mass or less, more preferably 1% by mass or less, and 0. It is preferably .0001% by mass or more and 3% by mass or less, and more preferably 0.001% by mass or more and 1% by mass or less.

The external preparation for skin of the present invention contains solid spherical borosilicate particles.
The average particle size of the solid spherical borosilicate particles is preferably 0.1 μm or more, more preferably 1 μm or more, further preferably 5 μm or more, and even more preferably 7 μm or more. The average particle size of the solid spherical borosilicate particles is preferably 20 μm or less, more preferably 15 μm or less, and even more preferably 13 μm or less. For example, the average particle size of the solid spherical borosilicate particles is preferably 1 to 20 μm, more preferably 5 to 15 μm, and further preferably 7 to 13 μm from the viewpoint of the stickiness reducing effect. The average particle size of the solid spherical borosilicate particles can be measured as the average particle size of the number average according to the principle of microscopy according to the shape of the powder particles.

In the solid spherical borosilicate particles, the borosilicate may be an alkali metal salt such as Na or K, an alkaline earth metal salt such as Mg or Ca, an Al salt, or a combination thereof. It is preferably Na borosilicate, Ca borosilicate, Al borosilicate, borosilicate (Ca / Na), borosilicate (Ca / Al), and more preferably borosilicate (Ca / Na).
The solid spherical borosilicate particles are displayed as borosilicate (Ca / Na) (CALCIUM SODIUM BOROSILICATE), borosilicate (Ca / Al) (CALCIUM ALUMINUM BOROSILICATE), etc. as cosmetic labeling names (INCI name). In the present invention, solid spherical borosilicate particles having any display name may be used, and it is more preferable to use borosilicate (Ca / Na).

The blending amount of the solid spherical borosilicate particles is not particularly limited, but is preferably 0.01% by mass or more, more preferably 0.1% by mass or more, still more preferably 1% by mass or more, based on the total amount of the external preparation for skin. The blending amount of the solid spherical borosilicate particles is not particularly limited, but is preferably 30% by mass or less, more preferably 20% by mass or less, still more preferably 10% by mass or less, based on the total amount of the external preparation for skin.
For example, the blending amount of the solid spherical borosilicate particles is preferably 0.01 to 30% by mass, more preferably 0.1 to 20% by mass, and further preferably 1 to 10 with respect to the total amount of the external preparation for skin. It is mass%. For example, in a water-based or oil-based dosage form for external skin preparation, the solid spherical borosilicate particles are more preferably 0.01 to 10% by mass based on the total amount of the external preparation for skin. Further, in the powdery or solid dosage form of the external preparation for skin, the solid spherical borosilicate particles are more preferably 0.1 to 20% by mass based on the total amount of the external preparation for skin.

The solid spherical borosilicate particles may be untreated, or may be hydrophilized or hydrophobized.

When the solid spherical borosilicate particles of the present invention are blended with an external preparation for skin, by using zinc oxide-coated solid spherical borosilicate particles coated with zinc oxide, a sebum solidifying effect is exhibited and makeup retention is improved. Can be made to.

The zinc oxide used in the zinc oxide-coated solid spherical borosilicate particles of the present invention is not particularly limited as long as it can be blended with an external preparation for skin. The shape of zinc oxide is not particularly limited. The average particle size of zinc oxide is preferably 10 to 200 nm, more preferably 15 to 100 nm, and even more preferably 15 to 50 nm from the viewpoint of sebum solidifying ability. The average particle size of zinc oxide is a volume-based average particle size, and can be measured by a laser diffraction / scattering type particle size distribution measuring device.

The zinc oxide-coated solid spherical borosilicate particles can be obtained, for example, by coating the solid spherical borosilicate particles with zinc oxide powder. It is preferable to use fine particles of zinc oxide as the zinc oxide powder.
As the zinc oxide, untreated zinc oxide can be used as it is, but it is preferable to use zinc oxide that has been hydrophobized. The hydrophobizing agent is not particularly limited, and examples thereof include dimethicone, methylhydrogenpolysiloxane, and metal soap. Among these hydrophobizing agents, it is preferable to use dimethicone. The coating amount of the hydrophobizing agent may be an amount sufficient for hydrophobizing zinc oxide. Specifically, the mass ratio of zinc oxide to the hydrophobizing agent is preferably 85: 15-99: 1, and more preferably 90: 10-98: 2.

In the zinc oxide-coated solid spherical borosilicate particles used for the external preparation for skin of the present invention, the coating amount of zinc oxide is preferably 0.01 part by mass or more with respect to 1 part by mass of the solid spherical borosilicate particles, and is 0. More preferably, it is 0.05 parts by mass or more. Further, the coating amount of zinc oxide is preferably 2 parts by mass or less, and more preferably 1.5 parts by mass or less with respect to 1 part by mass of the solid spherical borosilicate particles. In this range, the sebum solidifying ability can be further enhanced and sebum collapse can be further prevented.
The amount of zinc oxide coated is preferably 0.01 to 2 parts by mass, more preferably 0.05 to 1.5 parts by mass with respect to 1 part by mass of the solid spherical borosilicate particles.

As a method for coating solid spherical borosilicate with zinc oxide, various methods known so far can be used, for example, a physicochemical mixed grinding method (dry or wet), a chemical deposition method, or the like. Can be used. From the viewpoint of the sebum solidifying ability of the zinc oxide-coated solid spherical borosilicate particles, a dry mixed grinding method can be preferably used.

The external preparation for skin of the present invention has a sebum-solidifying ability and exhibits an excellent cosmetic lasting effect by containing the above-mentioned solid spherical borosilicate particles, preferably zinc oxide-coated solid spherical borosilicate particles. be able to.

In the external preparation for skin of the present invention, the total amount of the hydrophilic polymer and the solid spherical borosilicate particles is preferably 0.1 to 10% by mass, more preferably 1 to 8% by mass, based on the total amount of the external preparation for skin. .. In the external preparation for skin of the present invention, the solid spherical borosilicate particles are preferably 0.01 to 1 part by mass, preferably 0.05 to 0.5 part by mass with respect to 1 part by mass of the hydrophilic polymer. Within this range, it is possible to improve the stickiness and long-lasting makeup of the external preparation for skin while obtaining the action of the hydrophilic polymer.

The external preparation for skin of the present invention contains an aqueous component. Examples of such an aqueous component include water, hydrophilic polymers other than the above, moisturizers, preservatives, dispersants, pH adjusters, defoamers, moisturizers and the like.

The external preparation for skin of the present invention can be used as a sunscreen cosmetic by blending metal oxide fine particles and an organic ultraviolet absorber.

The metal oxide fine particles are not particularly limited, but it is common to use one or two kinds selected from fine particle titanium oxide and fine particle zinc oxide. The metal oxide fine particles can be blended as they are in the external preparation for skin of the present invention, but it is also possible to use those previously dispersed in a silicone oil, an ester oil, or an aqueous component. Further, a powder obtained by coating the surface of a plate-shaped powder with metal oxide fine particles and a powder obtained by modifying the powder with a surface modifier can also be used.

The type of the organic ultraviolet absorber is not particularly limited, and a known organic ultraviolet absorber can be used without limitation. Examples of such known organic ultraviolet absorbers include silicic acid derivatives such as 2-ethylhexyl paramethoxycinerate, isopropyl methoxycinnamate, and isoamyl methoxycinnamate; paraaminobenzoic acid (hereinafter abbreviated as "PABA"). PABA derivatives such as ethyl PABA, ethyl-dihydroxypropyl PABA, ethylhexyl-dimethyl PABA, glyceryl PABA; salicylic acid derivatives such as homosalate, ethylhexyl salicylate, dipropylene glycol salicylate, TEA salicylate; benzophenone-1, benzophenone -2, Benzophenone-3 or oxybenzophenone, benzophenone-4, benzophenone-5, benzophenone-6, benzophenone-8, benzophenone-9, benzophenone-12 and other benzophenone derivatives; Benzophenone sulphonic derivatives such as sulfonic acid, methosulfate benzophenone sulconium, terephthalilidene sulphonic acid, polyacrylamide methyl benzylene sulphonate; anisotriazine, diethylhexylbutamidotriazone, 2,4,6-tris (diisobutyl-4 '-Aminobenzophenone) -s-triazine, 2,4-bis- [{4- (2-ethylhexyloxy) -2-hydroxy} -phenyl] -6- (4-methoxyphenyl) -1,3 , 5-Triazine, 2,4,6-Tris [4- (2-ethylhexyloxycarbonyl) anilino] -1,3,5-Triazine and other triazine derivatives; phenyldibenzoimidazole tetrasulfonate and other phenylbenzoimidazole Derivatives; phenylbenzotriazole derivatives such as drometrizoletrisiloxane, methylenebis (benzotriazolyltetramethylbutylphenol); anthranil derivatives such as menthyl anthranylate; imidazoline derivatives such as dimethoxybenzidyleneoxoimidazolidine propionate 2-ethylhexyl; benzal Benzophenone malonate derivatives such as polyorganosiloxane having malonate functional groups; 4,4-diarylbutadiene derivatives such as 1,1-dicarboxy (2,2'-dimethylpropyl) -4,4-diphenylbutadiene; octocrylene , 2- [4- (diethylamino) -2-hydroxybenzoyl] hexyl benzoate, 4-ter Examples thereof include t-butyl-4'-methoxydibenzoylmethane. The organic ultraviolet absorber may be used alone or in combination of two or more.

When the organic ultraviolet absorber is blended, the blending amount is preferably 1 to 20% by mass. If it is less than 1% by mass, a sufficient sunscreen effect cannot be obtained, and if it exceeds 20% by mass, it has an adverse effect on usability, such as stickiness and increased primary irritation to the skin.

In addition to the above-mentioned essential ingredients and optional ingredients, the external preparation for skin of the present invention includes oily ingredients, moisturizers, pigments, surfactants, thickeners, and beauty agents that are usually added to external preparations for skin as needed. Ingredients, fragrances, polymer substances, antibacterial and microscopic agents, alcohols, powders, scrubbing agents, biological components and the like can be appropriately blended.

The external preparation for skin of the present invention can be produced by a usual production method.

Hereinafter, the present invention will be described in more detail with reference to examples. However, the present invention is not limited to the following examples. The blending amount means mass% unless otherwise specified. As for the comparative example, the borosilicate (Ca / Na) or zinc oxide-coated borosilicate (Ca / Na) blended in the corresponding example was replaced with "a component blended in an amount of 100 in total" for the corresponding comparison. As an example. In addition, Examples or Comparative Examples were prepared by a conventional method.

The evaluation method of Examples and Comparative Examples will be described.
[Stickiness]
Clean the inside of the forearm with a predetermined amount of soap and wipe off the water from the forearm. Two areas of 3.0 cm × 3.0 cm were marked on the left and right forearms, and an appropriate amount was applied next to each other with a finger cot in the example or comparative example, and the judgment was made by consensus based on the following criteria. The subjects were three sensory evaluation specialists.
"○": The example is less sticky.
"Δ": Examples and comparative examples are equivalent.
"X": The comparative example is less sticky.
[Makeup]
For the sample evaluated for stickiness, the examples or comparative examples remaining on the medial side of the forearm after 4 hours were visually observed and comparatively evaluated.
"○": The remaining amount is larger in the examples.
"Δ": Examples and comparative examples are equivalent.
"X": The comparative example has a larger residual amount.

As borosilicate (Ca / Na), the trade name "COVABEAD CRYSTAL" (manufactured by SENSIENT COSMETIC TECHNOLOGIES; average particle size 11 μm) is used, and as zinc oxide-coated borosilicate (Ca / Na), the trade name is "Pulsair CBZ-NV". "(Made by Suzuki Oil & Fat Co., Ltd.) was used respectively. In addition, the following 5 types were used as the hydrophilic polymer.
Note 1: PEMULEN TR-1 (manufactured by Lubrizol)
Note 2: SEPINOV EMT10 (manufactured by SEPIC)
Note 3: ADEKA NOL GT-700 (manufactured by ADEKA)
Note 4: Kerkogel HM (manufactured by DSP Gokyo Food & Chemical Co., Ltd.)
Note 5: Carbopole 940 (manufactured by Lubrizol)

Tables 1 and 2 show formulation examples of the oil-in-water emulsified liquid foundation and their evaluation results. As shown in Tables 1 and 2, the examples in which the solid spherical borosilicate particles were blended had a better usability with less stickiness than the comparative examples in which the solid spherical borosilicate particles were not blended. In addition, Examples 6 to 10 containing zinc oxide-coated solid spherical borosilicate had better makeup retention than the corresponding comparative examples.

Tables 3 and 4 show prescription examples of oil-in-water emulsified sunscreens and their evaluation results. As shown in Tables 3 and 4, the examples in which the solid spherical borosilicate particles were blended had a better usability with less stickiness than the comparative examples in which the solid spherical borosilicate particles were not blended. In addition, Examples 16 to 20 containing zinc oxide-coated solid spherical borosilicate had better makeup retention than the corresponding comparative examples.

Table 5 shows prescription examples of emulsions and their evaluation results. As shown in Table 5, the example in which the solid spherical borosilicate particles were blended had a better feeling of use with less stickiness than the comparative example in which the solid spherical borosilicate particles were not blended.

Table 6 shows a prescription example of the cream and its evaluation result. As shown in Table 6, the examples in which the solid spherical borosilicate particles were blended had a better usability with less stickiness than the comparative examples in which the solid spherical borosilicate particles were not blended.

Table 7 shows a prescription example of the moisturizing gel and its evaluation result. As shown in Table 7, the examples in which the solid spherical borosilicate particles were blended had a better usability with less stickiness than the comparative examples in which the solid spherical borosilicate particles were not blended.

Claims (2)

An external preparation for skin, which contains one or more hydrophilic polymers selected from an acrylic polymer, a urethane polymer, and a polysaccharide polymer, and solid spherical borosilicate particles. .. The external preparation for skin according to claim 1, wherein the solid spherical borosilicate particles are solid spherical borosilicate particles coated with fine particles of zinc oxide.