JP2021008430A - Composition for health promotion, and pharmaceutical or food and drink containing said composition for health promotion - Google Patents
Composition for health promotion, and pharmaceutical or food and drink containing said composition for health promotion Download PDFInfo
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- JP2021008430A JP2021008430A JP2019122655A JP2019122655A JP2021008430A JP 2021008430 A JP2021008430 A JP 2021008430A JP 2019122655 A JP2019122655 A JP 2019122655A JP 2019122655 A JP2019122655 A JP 2019122655A JP 2021008430 A JP2021008430 A JP 2021008430A
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Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Description
本発明は、健康増進用組成物、及び当該健康増進用組成物を含む医薬品又は飲食品に関する。 The present invention relates to a health-promoting composition and a pharmaceutical product or food or drink containing the health-promoting composition.
健康を増進させる健康増進用組成物が、種々開発されている。
このような組成物として、例えば特許文献１に、有機ゲルマニウム化合物のみを主要な有効成分とする組成物が開示されている。
Various health-promoting compositions have been developed to promote health.
As such a composition, for example, Patent Document 1 discloses a composition containing only an organogermanium compound as a main active ingredient.
有機ゲルマニウム化合物は、体内に取り入れられると、抗酸化作用を奏し、活性酸素が一因とされる病気を改善及び予防すると考えられている。 Organogermanium compounds, when taken into the body, are thought to exert antioxidant effects and improve and prevent diseases caused by active oxygen.
有機ゲルマニウム化合物の効き目には、個人差がある虞がある。
そのため、有機ゲルマニウム化合物のみを主要な有効成分とする組成物を摂取しても、活性酸素が一因とされる病気を、改善及び予防することができない虞がある。
There may be individual differences in the effectiveness of organogermanium compounds.
Therefore, ingestion of a composition containing only an organogermanium compound as a main active ingredient may not be able to improve or prevent a disease caused by active oxygen.
本発明は、上記問題点に鑑みてなされたものであり、従来よりも、活性酸素が一因とされる病気を改善及び予防することが可能な健康増進用組成物、及び当該健康増進用組成物を含む医薬品又は飲食品を提供することを目的とする。 The present invention has been made in view of the above problems, and is a health-promoting composition capable of improving and preventing diseases caused by active oxygen, and the health-promoting composition, as compared with the conventional case. The purpose is to provide medicines or foods and drinks containing goods.
上記目的を達成するため、本発明の健康増進用組成物は、有機ゲルマニウム化合物と、食用珪素と、を含有する。 In order to achieve the above object, the health-promoting composition of the present invention contains an organogermanium compound and edible silicon.
例えば、前記食用珪素の含有量が、前記有機ゲルマニウム化合物の含有量よりも多くてもよい。 For example, the content of the edible silicon may be higher than the content of the organogermanium compound.
例えば、前記有機ゲルマニウム化合物の含有量が、０．０１質量％以上０．１０質量％以下であってもよい。 For example, the content of the organogermanium compound may be 0.01% by mass or more and 0.10% by mass or less.
本発明の医薬品又は飲食品は、前記健康増進用組成物を含む。 The pharmaceutical product or food or drink of the present invention contains the above-mentioned health-promoting composition.
本発明によれば、従来よりも、活性酸素が一因とされる病気を改善及び予防することが可能な健康増進用組成物、及び当該健康増進用組成物を含む医薬品又は飲食品を提供することができる。 According to the present invention, a health-promoting composition capable of improving and preventing a disease caused by active oxygen, and a drug or food or drink containing the health-promoting composition are provided. be able to.
以下、本発明の実施の形態に係る健康増進用組成物について説明する。 Hereinafter, the health-promoting composition according to the embodiment of the present invention will be described.
本発明の健康増進用組成物は、有効成分として、有機ゲルマニウム化合物と、食用珪素と、を含有する。 The health-promoting composition of the present invention contains an organogermanium compound and edible silicon as active ingredients.
有機ゲルマニウム化合物は、化学構造の中に、ゲルマニウム（Ｇｅ）と炭素（Ｃ）との結合を含む化合物である。
有機ゲルマニウム化合物は、特に限定されず、例えばカルボキシエチルゲルマニウムセスキオキサイド（（Ｇｅ−ＣＨ２−ＣＨ２−ＣＯＯＨ）２Ｏ３）、カルボキシエチルゲルマニウムセスキスルフィド（（Ｇｅ−ＣＨ２−ＣＨ２−ＣＯＯＨ）２Ｓ３）、ポリ−トランス−二−カルボキシエチルゲルマセスキオキサン（［（ＧｅＣＨ２ＣＨ２ＣＯＯＨ）２Ｏ３］ｎ）を挙げることができる。
Organogermanium compounds are compounds that contain a bond between germanium (Ge) and carbon (C) in their chemical structure.
Organogermanium compound is not particularly limited, for example, carboxyethyl germanium sesqui oxide ((Ge-CH 2 -CH 2 -COOH) 2 O 3), carboxyethyl germanium Seth Kiss sulfide ((Ge-CH 2 -CH 2 -COOH) 2 S 3 ), poly-trans-2-carboxyethyl germanium sesquioxane ([(GeCH 2 CH 2 COOH) 2 O 3 ] n) can be mentioned.
また、有機ゲルマニウム化合物は、天然由来のものであってもよく、人工的に合成されたものであってもよい。 Further, the organogermanium compound may be of natural origin or may be artificially synthesized.
天然由来の有機ゲルマニウム化合物としては、特に限定されないが、例えばオタネニンジン（Ｐａｎａｘ ｇｉｎｓｅｎｇ Ｃ．Ａ．Ｍｅｙｅｒ）、三七人参（Ｐａｎａｘ ｐｓｅｕｄｏｇｉｎｓｅｎｇ）、田七人参（Ｓｅｕ ｒａｄｉｘ ｎｏｔｏｐｔｅｒｙｇｉｉ）、霊芝（Ｇａｎｏｄｅｒｍａ ｌｕｃｉｄｕｍ）、ニンニク（Ａｌｌｉｕｍ ｓａｔｉｖｕｍ）、クロレラ（Ｃｈｌｏｒｅｌｌａ Ｖｕｌｇａｒｉｓ）、アロエ（Ａｌｏｅ ａｒｂｏｒｅｓｃｅｎｓ）、山薬（Ｄｉｏｓｃｏｒｅａ ｂａｔａｔａｓ）、百合（Ｌｉｌｕｍ ｓｐｐ．）、生姜（Ｚｉｎｇｉｂｅｒ ｏｆｆｉｃｉｎａｌｅ）、サルノコシカケ（Ｆｏｍｉｔｏｐｓｉｓ ｎｉｇｒａ）、米糠（Ｏｒｙｚａ ｓａｔｉｖａ Ｌ．）、シイタケ（Ｌｅｎｔｉｎｕｌａ ｅｄｏｄｅｓ）等の植物から抽出される有機ゲルマニウム化合物を挙げることができる。
なお、これらの植物から有機ゲルマニウム化合物を抽出する際の抽出溶媒としては、特に限定されないが、例えば水、エタノール、アセトンを挙げることができる。
Naturally-derived organic germanium compounds are not particularly limited, and are, for example, Panax ginseng CA Meyer, Panax notoginseng, Seu radix notoginseng, Ganoderma lucidum (Ganoderma lucidum), and Ganoderma lucidum (Ganoderma lucidum). Ginseng (Allium sativum), Chlorella (Chlorella Vulgaris), Aloe (Aloe arboressens), Yamayaku (Dioscorea batatas), Yuri (Lilum spp.) ), Organic germanium compounds extracted from plants such as Panax notoginseng (Lentinula edodes).
The extraction solvent for extracting the organogermanium compound from these plants is not particularly limited, and examples thereof include water, ethanol, and acetone.
また、人工的に合成された有機ゲルマニウム化合物としては、特に限定されず、公知の方法により合成された有機ゲルマニウム化合物であってもよい。
公知の方法としては、例えば、トリクロルゲルマン（Ｃｌ３ＧｅＨ）をアクリル酸（ＣＨ２ＣＨＣＯＯＨ）と反応させてトリクロルゲルミルプルピオン酸（Ｃｌ３ＧｅＣＨ２ＣＨ２ＣＯＯＨ）を製造し、製造されたトリクロルゲルミルプルピオン酸を加水分解する方法を挙げることができる。
Further, the artificially synthesized organic germanium compound is not particularly limited, and may be an organic germanium compound synthesized by a known method.
As a known method, for example, trichlorogerman (Cl 3 GeH) is reacted with acrylic acid (CH 2 CHCOOH) to produce trichlorogelmilpurupionic acid (Cl 3 GeCH 2 CH 2 COOH), and the produced trichlor is produced. Examples thereof include a method of hydrolyzing gelmilpurupionic acid.
また、有機ゲルマニウム化合物は、市販のものであってもよい。
市販の有機ゲルマニウム化合物としては、特に限定されないが、例えば、株式会社浅井ゲルマニウム研究所から販売されている「アサイゲルマニウム」等が挙げられる。
Moreover, the organic germanium compound may be commercially available.
The commercially available organogermanium compound is not particularly limited, and examples thereof include "acai germanium" sold by Asai Germanium Research Institute, Ltd.
食用珪素は、非晶質珪素であり、例えば、食物由来の珪素や、鉱物由来の珪素が挙げられる。
食物由来の珪素としては、穀類、野菜類、海藻類などに含まれる珪素が挙げられる。
穀類としては、例えば、麦、玄米、白米、トウモロコシである。
野菜類としては、例えば、ゴボウ、大根、人参である。
海藻類としては、例えば、昆布、ワカメである。
穀類、野菜類、海藻類などの食物は、粉砕された状態で、本発明の健康増進用組成物に含有されていてもよい。
The edible silicon is amorphous silicon, and examples thereof include silicon derived from food and silicon derived from minerals.
Examples of food-derived silicon include silicon contained in cereals, vegetables, seaweeds, and the like.
Examples of cereals are wheat, brown rice, white rice, and corn.
Examples of vegetables include burdock, radish, and carrot.
Examples of seaweeds include kelp and wakame seaweed.
Foods such as cereals, vegetables, and seaweeds may be contained in the health-promoting composition of the present invention in a crushed state.
鉱物由来の珪素としては、水晶から抽出した珪素が挙げられる。 Examples of mineral-derived silicon include silicon extracted from quartz.
また、食用珪素は、市販の食用珪素であってもよく、例えば、株式会社ＡＰＡコーポレーションから販売されている水溶性珪素「ｕｍｏ（登録商標）」に含まれている珪素が挙げられる。 Further, the edible silicon may be commercially available edible silicon, and examples thereof include silicon contained in the water-soluble silicon "umo (registered trademark)" sold by APA Corporation.
また、食用珪素は、単体の珪素であってもよいし、例えば二酸化珪素のように化合物中の珪素であってもよい。 Further, the edible silicon may be a simple substance of silicon, or may be silicon in a compound such as silicon dioxide.
食用珪素は、人体に摂取されると、腸管から吸収されて、細胞中のミトコンドリアを活性化しつつ、体内の活性酸素の過剰な増加を防ぐ。
つまり、食用珪素を摂取すると、その抗酸化作用により、活性酸素が一因とされる病気を、改善及び予防することが可能になる。
When edible silicon is ingested by the human body, it is absorbed from the intestinal tract and activates mitochondria in cells while preventing an excessive increase in active oxygen in the body.
In other words, when edible silicon is ingested, its antioxidant action makes it possible to improve and prevent diseases caused by active oxygen.
このような本発明の健康増進用組成物によれば、有機ゲルマニウム化合物の抗酸化作用に加え、食用珪素の抗酸化作用が得られる。
そのため、本発明の健康増進用組成物を摂取することで、有機ゲルマニウム化合物のみを主要な有効成分とする組成物を摂取する場合と比較して、活性酸素が一因とされる病気を、より改善及び予防することが可能になる。
According to such a health-promoting composition of the present invention, in addition to the antioxidant action of the organogermanium compound, the antioxidant action of edible silicon can be obtained.
Therefore, by ingesting the health-promoting composition of the present invention, as compared with the case of ingesting a composition containing only an organogermanium compound as a main active ingredient, diseases caused by active oxygen are more likely to be caused. It will be possible to improve and prevent.
ここで、活性酸素が一因とされる病気としては、特に限定されないが、例えば、動脈硬化、心筋梗塞、癌、糖尿病、肌荒れなどの病気が挙げられる。 Here, the disease caused by active oxygen is not particularly limited, and examples thereof include diseases such as arteriosclerosis, myocardial infarction, cancer, diabetes, and rough skin.
ここで、本発明の健康増進用組成物に含まれる有機ゲルマニウム化合物及び食用珪素の含有量は、特に限定されない。
ただし、食用珪素の含有量が、有機ゲルマニウム化合物の含有量よりも多いことが好ましい。これにより、活性酸素が一因とされる病気を、さらに改善及び予防することが可能になると考えられる。
Here, the contents of the organogermanium compound and edible silicon contained in the health-promoting composition of the present invention are not particularly limited.
However, it is preferable that the content of edible silicon is higher than the content of the organogermanium compound. It is considered that this makes it possible to further improve and prevent diseases caused by active oxygen.
また、本発明の健康増進用組成物の総質量に基づく有機ゲルマニウム化合物の含有量は、０．０１質量％以上０．２０質量％以下であることが好ましく、０．０１質量％以上０．１０質量％以下であることがさらに好ましく、０．０１質量％以上０．０３質量％以下であることが最も好ましい。
これにより、本発明の健康増進用組成物を摂取した際に、有機ゲルマニウム化合物に特有の酸味等をなるべく感じさせることなく、活性酸素が一因とされる病気を改善及び予防することが可能になる。
なお、本発明の健康増進用組成物の総質量に基づく有機ゲルマニウム化合物の含有量について、好ましいのは０．０１質量％以上０．２０質量％以下であるから、例えば０．０２質量％、０．０４質量％、０．０５質量％、０．０６質量％、０．０７質量％、０．０８質量％、０．０９質量％、０．１１質量％、０．１２質量％、０．１３質量％、０．１４質量％、０．１５質量％、０．１６質量％、０．１７質量％、０．１８質量％、０．１９質量％が含まれる。
The content of the organogermanium compound based on the total mass of the health-promoting composition of the present invention is preferably 0.01% by mass or more and 0.20% by mass or less, preferably 0.01% by mass or more and 0.10. It is more preferably mass% or less, and most preferably 0.01 mass% or more and 0.03 mass% or less.
As a result, when the health-promoting composition of the present invention is ingested, it is possible to improve and prevent diseases caused by active oxygen without making the sourness peculiar to the organogermanium compound felt as much as possible. Become.
The content of the organic germanium compound based on the total mass of the health-promoting composition of the present invention is preferably 0.01% by mass or more and 0.20% by mass or less. Therefore, for example, 0.02% by mass or 0. .04 mass%, 0.05 mass%, 0.06 mass%, 0.07 mass%, 0.08 mass%, 0.09 mass%, 0.11 mass%, 0.12 mass%, 0.13 It includes mass%, 0.14 mass%, 0.15 mass%, 0.16 mass%, 0.17 mass%, 0.18 mass%, and 0.19 mass%.
また、本発明の健康増進用組成物に含まれる有機ゲルマニウム化合物は、特に限定されないが、ポリ−トランス−二−カルボキシエチルゲルマセスキオキサンであることが好ましい。
この理由は、ポリ−トランス−二−カルボキシエチルゲルマセスキオキサンが、抗酸化作用に加え、ＮＫ細胞を活性化させるなどの抗ウイルス作用、骨代謝に関与するホルモンバランスを調整する作用、赤血球の代謝を促進し血液の流動性を改善する作用、血圧調整作用、及び胆汁成分の分泌を促進させる作用などを奏すると考えられているからである。ここで、胆汁成分の分泌を促進させる作用とは、胆汁色素や胆汁酸が、消化管へ分泌するのを促進させる作用である。
The organogermanium compound contained in the health-promoting composition of the present invention is not particularly limited, but is preferably poly-trans-2-carboxyethyl germanium sesquioxane.
The reason for this is that poly-trans-2-carboxyethyl germaneskioxane has an antiviral effect such as activating NK cells, an effect of adjusting the hormone balance involved in bone metabolism, and an effect of erythrocytes. This is because it is considered to have an action of promoting metabolism and improving blood fluidity, an action of regulating blood pressure, and an action of promoting secretion of bile components. Here, the action of promoting the secretion of bile components is the action of promoting the secretion of bile pigments and bile acids into the digestive tract.
その為、本発明の健康増進用組成物に含まれる有機ゲルマニウム化合物を、ポリ−トランス−二−カルボキシエチルゲルマセスキオキサンとすることで、その抗酸化作用により、活性酸素が一因とされる病気を改善及び予防できることに加え、その抗ウイルス作用、骨代謝に関与するホルモンバランスを調整する作用、赤血球の代謝を促進し血液の流動性を改善する作用、血圧調整作用、及び胆汁成分の分泌を促進させる作用などにより、その他の病気を改善及び予防することが可能になる。
なお、ポリ−トランス−二−カルボキシエチルゲルマセスキオキサンは、上記の作用に加え、鎮痛作用も示すと考えられている。
Therefore, by changing the organogermanium compound contained in the health-promoting composition of the present invention to poly-trans-2-carboxyethyl germaneskioxane, active oxygen is considered to be one of the causes due to its antioxidant action. In addition to being able to improve and prevent diseases, its antiviral effect, its effect of adjusting the hormone balance involved in bone metabolism, its effect of promoting the metabolism of red blood cells and improving blood fluidity, its blood pressure regulating effect, and the secretion of bile components It becomes possible to improve and prevent other diseases by the action of promoting blood pressure.
It is believed that poly-trans-2-carboxyethyl germaneskioxane also exhibits an analgesic effect in addition to the above-mentioned effects.
なお、本発明は、上記実施の形態に限定されず、種々の変形及び応用が可能である。 The present invention is not limited to the above embodiment, and various modifications and applications are possible.
例えば、本発明の健康増進用組成物は、必要に応じて、さらに、有機ゲルマニウム化合物や食用珪素とは関連しない成分であって、抗酸化作用を奏する成分を含んでもよい。
このような抗酸化作用を奏する成分としては、特に限定されないが、例えばγ−オリザノール、アルファリポ酸、カテキン類、フラボノイド、コエンザイムＱ１０、ビタミンＣ、ビタミンＥ、アルファカロテン、ベータカロテン、エンゾジノール、ローヤルゼリー、尿酸及びクエン酸などを挙げることができる。
本発明の健康増進用組成物は、必要に応じて、これらの抗酸化作用を奏する成分の少なくとも１つ以上を含有してもよい。
For example, the health-promoting composition of the present invention may further contain a component that is not related to the organogermanium compound or edible silicon and has an antioxidant effect, if necessary.
The components having such an antioxidant effect are not particularly limited, but for example, γ-oryzanol, alpha lipoic acid, catechins, flavonoids, coenzyme Q10, vitamin C, vitamin E, alpha carotene, beta carotene, enzogenol, royal jelly, etc. Examples include uric acid and citric acid.
The health-promoting composition of the present invention may contain at least one or more of these antioxidant components, if necessary.
そして、本発明の健康増進用組成物に、上記のγ−オリザノール、アルファリポ酸、カテキン類、フラボノイド、コエンザイムＱ１０、ビタミンＣ、ビタミンＥ、アルファカロテン、ベータカロテン、エンゾジノール、ローヤルゼリー、尿酸及びクエン酸などを含有させる場合、それらの含有量は、特に限定されない。 Then, the above-mentioned γ-oryzanol, alpha lipoic acid, catechins, flavonoids, coenzyme Q10, vitamin C, vitamin E, alpha carotene, beta carotene, enzogenol, royal jelly, uric acid and citric acid are added to the health-promoting composition of the present invention. When and the like are contained, their content is not particularly limited.
また、本発明の健康増進用組成物は、必要に応じて、賦形剤、ｐＨ調整剤、清涼化剤、懸濁化剤、コーティング剤、着色剤、結合剤、滑沢剤、及び界面活性剤などを含有してもよい。 In addition, the health-promoting composition of the present invention contains excipients, pH adjusters, cooling agents, suspending agents, coating agents, colorants, binders, lubricants, and surfactants, as required. It may contain an agent or the like.
賦形剤としては、特に限定されず、例えば、デンプン、乳糖、白糠、ラクトース、微結晶セルロース、スクロース、デキストリン、Ｄ−マンニトール、コーンスターチ、リン酸カルシウム、リン酸水素カルシウム、硫酸カルシウム、カルボキシメチルスターチナトリウム、メタケイ酸有アルミン酸マグネシウム、ポリエチレングリコール、中鎖脂肪酸トリグリセリドなどが挙げられる。
本発明の健康増進用組成物は、必要に応じて、これらの１つ以上の賦形剤を含有してもよい。
The excipient is not particularly limited, and for example, starch, lactose, white bran, lactose, microcrystalline cellulose, sucrose, dextrin, D-mannitol, corn starch, calcium phosphate, calcium hydrogen phosphate, calcium sulfate, sodium carboxymethyl starch, and the like. Examples thereof include magnesium aluminome with metasilicate, polyethylene glycol, and medium-chain fatty acid triglyceride.
The health-promoting composition of the present invention may contain one or more of these excipients, if necessary.
ｐＨ調整剤としては、特に限定されず、例えば、クエン酸、乳酸、リンゴ酸、アスパラギン酸、重曹、水酸化ナトリウム、リン酸水素ナトリウム、水酸化カリウム、水酸化マグネシウムなどが挙げられる。
本発明の健康増進用組成物は、必要に応じて、これらの１つ以上のｐＨ調整剤を含有してもよい。
The pH adjuster is not particularly limited, and examples thereof include citric acid, lactic acid, malic acid, aspartic acid, baking soda, sodium hydroxide, sodium hydrogen phosphate, potassium hydroxide, and magnesium hydroxide.
The health-promoting composition of the present invention may contain one or more of these pH adjusters, if necessary.
清涼化剤としては、特に限定されず、例えば、ｌ−メントール、ハッカ水などが挙げられる。
本発明の健康増進用組成物は、必要に応じて、これらの１以上の清涼化剤を含有してもよい。
The refreshing agent is not particularly limited, and examples thereof include l-menthol and mint water.
The health-promoting composition of the present invention may contain one or more of these refreshing agents, if necessary.
懸濁化剤としては、特に限定されず、例えば、カルボキシメチルセルロース、ヒドロキシメチルセルロース、ポリビニルアルコール、ポリビニルピロリドン、カオリン、カルメロースナトリウムなどが挙げられる。
本発明の健康増進用組成物は、必要に応じて、これらの１つ以上の懸濁化剤を含有してもよい。
The suspending agent is not particularly limited, and examples thereof include carboxymethyl cellulose, hydroxymethyl cellulose, polyvinyl alcohol, polyvinylpyrrolidone, kaolin, and carmellose sodium.
The health-promoting composition of the present invention may contain one or more of these suspending agents, if necessary.
コーティング剤としては、特に限定されず、例えば、ヒドロキシメチルセルロース、ヒドロキシプロピルセルロース、カルボキシメチルエチルセルロース、ポリオキシエチレングリコール、セルロースアセテートフタレート、ポリビニルアセタールジエチルアミノアセテート、セルロースアセテートトリメリテート、ポリビニルアセテートフタレート、ヒドロキシプロピルメチルセルロースアセテートサクシネート、ヒドロキシプロピルメチルセルロースフタレート、メタクリレートコポリマーなどが挙げられる。
本発明の健康増進用組成物は、必要に応じて、これらの１つ以上のコーティング剤を含有してもよい。
The coating agent is not particularly limited, and for example, hydroxymethyl cellulose, hydroxypropyl cellulose, carboxymethyl ethyl cellulose, polyoxyethylene glycol, cellulose acetate phthalate, polyvinyl acetal diethylamino acetate, cellulose acetate trimellitate, polyvinyl acetate phthalate, hydroxypropyl methyl cellulose. Acetate succinate, hydroxypropylmethyl cellulose phthalate, methacrylate copolymer and the like can be mentioned.
The health-promoting composition of the present invention may contain one or more of these coating agents, if necessary.
着色剤としては、特に限定されず、例えば、タール色素、酸化チタン、ウコン抽出液、リボフラビンなどが挙げられる。
本発明の健康増進用組成物は、必要に応じて、これらの１つ以上の着色剤を含有してもよい。
The colorant is not particularly limited, and examples thereof include tar pigment, titanium oxide, turmeric extract, and riboflavin.
The health-promoting composition of the present invention may contain one or more of these colorants, if necessary.
結合剤としては、特に限定されず、例えば、エタノール、プロパノール、ポリビニルアルコール、メチルセルロース、エチルセルロース、カルボキシメチルセルロース、ヒドロキシプロピルセルロース、ヒドロキシプロピルメチルセルロース、ゼラチン、デンプン、ブドウ糖、アラビアゴム、リン酸カルシウム、アルギン酸ナトリウム、アルギン酸プロピレングリコールエステルなどが挙げられる。
本発明の健康増進用組成物は、必要に応じて、これらの１つ以上の結合剤を含有してもよい。
The binder is not particularly limited, and for example, ethanol, propanol, polyvinyl alcohol, methyl cellulose, ethyl cellulose, carboxymethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, gelatin, starch, glucose, gum arabic, calcium phosphate, sodium alginate, propylene alginate. Glycol ester and the like can be mentioned.
The health-promoting composition of the present invention may contain one or more of these binders, if necessary.
滑沢剤としては、特に限定されず、例えば、ステアリン酸マグネシウム、ステアリン酸カルシウム、コロイダルシリカ、ショ糖脂肪酸エステル、フマル酸ステアリルナトリウム、タルク、ポリエチレングリコールなどが挙げられる。
本発明の健康増進用組成物は、必要に応じて、これらの１つ以上の滑沢剤を含有してもよい。
The lubricant is not particularly limited, and examples thereof include magnesium stearate, calcium stearate, colloidal silica, sucrose fatty acid ester, sodium stearyl fumarate, talc, and polyethylene glycol.
The health-promoting composition of the present invention may contain one or more of these lubricants, if necessary.
界面活性剤としては、特に限定されず、例えば、ラウリル硫酸ナトリウム、ポリソルベート８０、Ｔｗｅｅｎ６０、Ｔｗｅｅｎ８０、ポリオキシエチレン硬化ヒマシ油、モノステアリンサングリセリン、グリセリン脂肪酸エステル、ポリグリセリン脂肪酸エステル、ショ糖脂肪酸エステル、プロピレングリコール、モノステアリン酸ソルビタン、モノラウリン酸ソルビタンなどが挙げられる。
本発明の健康増進用組成物は、必要に応じて、これらの１つ以上の界面活性剤を含有してもよい。
The surfactant is not particularly limited, and for example, sodium lauryl sulfate, polysorbate 80, Tween 60, Tween 80, polyoxyethylene hydrogenated castor oil, monostearic acid sanglycerin, glycerin fatty acid ester, polyglycerin fatty acid ester, sucrose fatty acid ester, etc. Examples thereof include propylene glycol, sorbitan monostearate, and sorbitan monolaurate.
The health-promoting composition of the present invention may contain one or more of these surfactants, if necessary.
また、本発明の健康増進用組成物は、医薬品又は飲食品に含まれてもよい。 In addition, the health-promoting composition of the present invention may be contained in a pharmaceutical product or a food or drink.
医薬品に含まれる場合は、特に限定されないが、例えば、薬学的に許容される担体とともに、錠剤、カプセル剤、液剤、粉末剤、ペースト状剤、ゲル状剤などの形態で人体に投与される。 When it is contained in a pharmaceutical product, it is administered to the human body in the form of tablets, capsules, liquids, powders, pastes, gels and the like together with a pharmaceutically acceptable carrier, for example.
飲食品は、飲料品又は食料品を意味し、特に限定されないが、例えば、果汁飲料、清涼飲料、コーヒー、野菜ジュース、茶、コーヒー、シロップ、食酢、味噌、果物、野菜、穀物、肉、乳製品、菓子、麺、ゼリー、栄養補助食品、機能性食品、健康食品などが挙げられる。 Foods and drinks mean beverages or foods, and are not particularly limited, for example, fruit juice drinks, soft drinks, coffee, vegetable juices, tea, coffee, syrup, vinegar, miso, fruits, vegetables, grains, meat, milk. Products, confectionery, noodles, jellies, nutritional supplements, functional foods, health foods, etc. may be mentioned.
Claims (4)
健康増進用組成物。 Containing an organogermanium compound and edible silicon,
A composition for promoting health.
請求項１に記載の健康増進用組成物。 The content of the edible silicon is higher than the content of the organogermanium compound.
The health-promoting composition according to claim 1.
請求項１又は２に記載の健康増進用組成物。 The content of the organogermanium compound is 0.01% by mass or more and 0.10% by mass or less.
The health-promoting composition according to claim 1 or 2.
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