JP2021001177A5 - - Google Patents
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- Publication number
- JP2021001177A5 JP2021001177A5 JP2020143429A JP2020143429A JP2021001177A5 JP 2021001177 A5 JP2021001177 A5 JP 2021001177A5 JP 2020143429 A JP2020143429 A JP 2020143429A JP 2020143429 A JP2020143429 A JP 2020143429A JP 2021001177 A5 JP2021001177 A5 JP 2021001177A5
- Authority
- JP
- Japan
- Prior art keywords
- pkc
- inhibitor
- lsd
- csc
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- HKOWATVSFKRXRW-UHFFFAOYSA-N 4-n-[[4-(aminomethyl)cyclohexyl]methyl]-5-nitro-2-n-[[2-(trifluoromethoxy)phenyl]methyl]pyrimidine-2,4-diamine Chemical compound C1CC(CN)CCC1CNC1=NC(NCC=2C(=CC=CC=2)OC(F)(F)F)=NC=C1[N+]([O-])=O HKOWATVSFKRXRW-UHFFFAOYSA-N 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 102000001892 Protein Kinase C-theta Human genes 0.000 claims 1
- 108010015499 Protein Kinase C-theta Proteins 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 208000037819 metastatic cancer Diseases 0.000 claims 1
- 208000011575 metastatic malignant neoplasm Diseases 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2014903345 | 2014-08-25 | ||
| AU2014903345A AU2014903345A0 (en) | 2014-08-25 | Compositions for Modulating Cancer Stem Cells and Uses Therefor |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017511233A Division JP2017528452A (ja) | 2014-08-25 | 2015-08-25 | がん幹細胞を調節するための組成物およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021001177A JP2021001177A (ja) | 2021-01-07 |
| JP2021001177A5 true JP2021001177A5 (enExample) | 2021-02-18 |
Family
ID=55398499
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017511233A Pending JP2017528452A (ja) | 2014-08-25 | 2015-08-25 | がん幹細胞を調節するための組成物およびその使用 |
| JP2020143429A Pending JP2021001177A (ja) | 2014-08-25 | 2020-08-27 | がん幹細胞を調節するための組成物およびその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017511233A Pending JP2017528452A (ja) | 2014-08-25 | 2015-08-25 | がん幹細胞を調節するための組成物およびその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10485772B2 (enExample) |
| EP (1) | EP3185858A4 (enExample) |
| JP (2) | JP2017528452A (enExample) |
| CN (1) | CN107106517A (enExample) |
| AU (1) | AU2015309686B2 (enExample) |
| CA (1) | CA2958704A1 (enExample) |
| SG (1) | SG11201701237QA (enExample) |
| WO (1) | WO2016029262A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI3381896T3 (fi) | 2015-11-27 | 2023-04-21 | Taiho Pharmaceutical Co Ltd | Bifenyyliyhdiste tai sen suola |
| JP7341451B2 (ja) * | 2016-02-01 | 2023-09-11 | エピアクシス セラピューティクス プロプライアタリー リミティド | タンパク質性化合物とその利用 |
| SG11201901624RA (en) * | 2016-09-07 | 2019-03-28 | Univ Canberra | Lysine specific histone demethylase-1 inhibitors and uses therefor |
| WO2018059549A1 (en) * | 2016-09-30 | 2018-04-05 | Novartis Ag | Immune effector cell therapies with enhanced efficacy |
| WO2018216795A1 (ja) * | 2017-05-26 | 2018-11-29 | 大鵬薬品工業株式会社 | 新規なビフェニル化合物を用いた抗腫瘍効果増強剤 |
| RU2765152C2 (ru) | 2017-05-26 | 2022-01-26 | Тайхо Фармасьютикал Ко., Лтд. | Новое соединение бифенила или его соль |
| AU2018276611B2 (en) | 2017-05-31 | 2022-01-06 | Taiho Pharmaceutical Co., Ltd. | Method for predicting therapeutic effect of LSD1 inhibitor based on expression of INSM1 |
| CN111587120A (zh) * | 2017-11-08 | 2020-08-25 | 艾比克斯治疗私人有限公司 | 免疫原性组合物及其用途 |
| AU2018377852B2 (en) * | 2017-11-29 | 2022-03-24 | Epiaxis Therapeutics Pty Ltd | Enhancing T-cell function and treating a T-cell dysfunctional disorder with a combination of an LSD inhibitor and a PD1 binding antagonist |
| KR102125960B1 (ko) * | 2018-10-15 | 2020-06-25 | 한국생명공학연구원 | 세포 리프로그래밍 조성물 및 이를 이용한 유도만능줄기세포의 제조방법 |
| MX2022005811A (es) | 2019-11-13 | 2022-06-08 | Taiho Pharmaceutical Co Ltd | Sal novedosa de compuesto de terfenilo. |
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| WO2012009475A1 (en) * | 2010-07-14 | 2012-01-19 | Oregon Health & Science University | Methods of treating cancer with inhibition of lysine-specific demethylase 1 |
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| BR112014002939A2 (pt) | 2011-08-09 | 2017-03-01 | Takeda Pharmaceuticals Co | composto, medicamento, método para profilaxia ou tratamento de doença, a doença sendo esquizofrenia, alzheimer, parkinson ou huntington, uso do composto, e, método para inibir o lsd1 |
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| WO2014084298A1 (ja) * | 2012-11-28 | 2014-06-05 | 京都府公立大学法人 | リシン構造を有するlsd1選択的阻害薬 |
| US9144555B2 (en) | 2012-11-30 | 2015-09-29 | Darlene E. McCord | Hydroxytyrosol and oleuropein compositions for induction of DNA damage, cell death and LSD1 inhibition |
| SG11201510369WA (en) | 2013-06-25 | 2016-01-28 | Univ Canberra | Methods and compositions for modulating cancer stem cells |
| CA2923765C (en) | 2013-09-18 | 2021-06-29 | University Of Canberra | Stem cell modulation ii |
-
2015
- 2015-08-25 AU AU2015309686A patent/AU2015309686B2/en active Active
- 2015-08-25 WO PCT/AU2015/050489 patent/WO2016029262A1/en not_active Ceased
- 2015-08-25 SG SG11201701237QA patent/SG11201701237QA/en unknown
- 2015-08-25 US US15/506,469 patent/US10485772B2/en active Active
- 2015-08-25 CA CA2958704A patent/CA2958704A1/en not_active Abandoned
- 2015-08-25 CN CN201580054149.0A patent/CN107106517A/zh active Pending
- 2015-08-25 EP EP15835730.1A patent/EP3185858A4/en not_active Withdrawn
- 2015-08-25 JP JP2017511233A patent/JP2017528452A/ja active Pending
-
2019
- 2019-11-13 US US16/682,170 patent/US20200289437A1/en not_active Abandoned
-
2020
- 2020-08-27 JP JP2020143429A patent/JP2021001177A/ja active Pending
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