AU2015309686B2 - Compositions for modulating cancer stem cells and uses therefor - Google Patents

Compositions for modulating cancer stem cells and uses therefor Download PDF

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AU2015309686B2
AU2015309686B2 AU2015309686A AU2015309686A AU2015309686B2 AU 2015309686 B2 AU2015309686 B2 AU 2015309686B2 AU 2015309686 A AU2015309686 A AU 2015309686A AU 2015309686 A AU2015309686 A AU 2015309686A AU 2015309686 B2 AU2015309686 B2 AU 2015309686B2
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cancer
metastatic
csc
pkc
inhibitor
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AU2015309686A1 (en
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Sudha RAO
Anjum ZAFAR
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Epiaxis Therapeutics Pty Ltd
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Epiaxis Therapeutics Pty Ltd
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
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    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57595—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving intracellular compounds
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    • G01N2333/91—Transferases (2.)
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AU2015309686A 2014-08-25 2015-08-25 Compositions for modulating cancer stem cells and uses therefor Active AU2015309686B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2014903345 2014-08-25
AU2014903345A AU2014903345A0 (en) 2014-08-25 Compositions for Modulating Cancer Stem Cells and Uses Therefor
PCT/AU2015/050489 WO2016029262A1 (en) 2014-08-25 2015-08-25 Compositions for modulating cancer stem cells and uses therefor

Publications (2)

Publication Number Publication Date
AU2015309686A1 AU2015309686A1 (en) 2017-03-09
AU2015309686B2 true AU2015309686B2 (en) 2020-05-14

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AU2015309686A Active AU2015309686B2 (en) 2014-08-25 2015-08-25 Compositions for modulating cancer stem cells and uses therefor

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US (2) US10485772B2 (enExample)
EP (1) EP3185858A4 (enExample)
JP (2) JP2017528452A (enExample)
CN (1) CN107106517A (enExample)
AU (1) AU2015309686B2 (enExample)
CA (1) CA2958704A1 (enExample)
SG (1) SG11201701237QA (enExample)
WO (1) WO2016029262A1 (enExample)

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FI3381896T3 (fi) 2015-11-27 2023-04-21 Taiho Pharmaceutical Co Ltd Bifenyyliyhdiste tai sen suola
JP7341451B2 (ja) * 2016-02-01 2023-09-11 エピアクシス セラピューティクス プロプライアタリー リミティド タンパク質性化合物とその利用
SG11201901624RA (en) * 2016-09-07 2019-03-28 Univ Canberra Lysine specific histone demethylase-1 inhibitors and uses therefor
WO2018059549A1 (en) * 2016-09-30 2018-04-05 Novartis Ag Immune effector cell therapies with enhanced efficacy
WO2018216795A1 (ja) * 2017-05-26 2018-11-29 大鵬薬品工業株式会社 新規なビフェニル化合物を用いた抗腫瘍効果増強剤
RU2765152C2 (ru) 2017-05-26 2022-01-26 Тайхо Фармасьютикал Ко., Лтд. Новое соединение бифенила или его соль
AU2018276611B2 (en) 2017-05-31 2022-01-06 Taiho Pharmaceutical Co., Ltd. Method for predicting therapeutic effect of LSD1 inhibitor based on expression of INSM1
CN111587120A (zh) * 2017-11-08 2020-08-25 艾比克斯治疗私人有限公司 免疫原性组合物及其用途
AU2018377852B2 (en) * 2017-11-29 2022-03-24 Epiaxis Therapeutics Pty Ltd Enhancing T-cell function and treating a T-cell dysfunctional disorder with a combination of an LSD inhibitor and a PD1 binding antagonist
KR102125960B1 (ko) * 2018-10-15 2020-06-25 한국생명공학연구원 세포 리프로그래밍 조성물 및 이를 이용한 유도만능줄기세포의 제조방법
MX2022005811A (es) 2019-11-13 2022-06-08 Taiho Pharmaceutical Co Ltd Sal novedosa de compuesto de terfenilo.

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