JP2020535799A5 - - Google Patents
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- Publication number
- JP2020535799A5 JP2020535799A5 JP2020515647A JP2020515647A JP2020535799A5 JP 2020535799 A5 JP2020535799 A5 JP 2020535799A5 JP 2020515647 A JP2020515647 A JP 2020515647A JP 2020515647 A JP2020515647 A JP 2020515647A JP 2020535799 A5 JP2020535799 A5 JP 2020535799A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- nucleic acid
- set forth
- diverse
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023090016A JP2023115024A (ja) | 2017-09-20 | 2023-05-31 | 新規の安定した抗体の可変領域フレームワークの組み合わせ |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17192206.5 | 2017-09-20 | ||
| EP17192206.5A EP3459968A1 (en) | 2017-09-20 | 2017-09-20 | Novel stable antibody variable domain framework combinations |
| PCT/EP2018/075377 WO2019057787A1 (en) | 2017-09-20 | 2018-09-19 | NEW STABLE COMBINATIONS OF VARIABLE DOMAINS OF ANTIBODIES |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023090016A Division JP2023115024A (ja) | 2017-09-20 | 2023-05-31 | 新規の安定した抗体の可変領域フレームワークの組み合わせ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020535799A JP2020535799A (ja) | 2020-12-10 |
| JP2020535799A5 true JP2020535799A5 (https=) | 2021-11-04 |
Family
ID=59982265
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020515647A Pending JP2020535799A (ja) | 2017-09-20 | 2018-09-19 | 新規の安定した抗体の可変領域フレームワークの組み合わせ |
| JP2023090016A Pending JP2023115024A (ja) | 2017-09-20 | 2023-05-31 | 新規の安定した抗体の可変領域フレームワークの組み合わせ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023090016A Pending JP2023115024A (ja) | 2017-09-20 | 2023-05-31 | 新規の安定した抗体の可変領域フレームワークの組み合わせ |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11421035B2 (https=) |
| EP (2) | EP3459968A1 (https=) |
| JP (2) | JP2020535799A (https=) |
| CN (1) | CN111133000A (https=) |
| AU (1) | AU2018335823B2 (https=) |
| CA (1) | CA3073882A1 (https=) |
| MA (1) | MA50159A (https=) |
| WO (1) | WO2019057787A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL243311B (en) * | 2013-06-26 | 2022-07-01 | Numab Therapeutics AG | New frameworks for antibodies |
| EP3816185A1 (en) | 2019-11-04 | 2021-05-05 | Numab Therapeutics AG | Multispecific antibody directed against pd-l1 and a tumor-associated antigen |
| EP3915580A1 (en) | 2020-05-29 | 2021-12-01 | Numab Therapeutics AG | Multispecific antibody |
| EP3988568A1 (en) | 2020-10-21 | 2022-04-27 | Numab Therapeutics AG | Combination treatment |
| WO2022136693A1 (en) | 2020-12-23 | 2022-06-30 | Numab Therapeutics AG | Antibody variable domains and antibodies having decreased immunogenicity |
| KR20230123981A (ko) | 2020-12-23 | 2023-08-24 | 누맙 세러퓨틱스 아게 | Il-4r에 결합하는 항체 가변 도메인 |
| EP4019090A1 (en) | 2020-12-23 | 2022-06-29 | Numab Therapeutics AG | Antibody variable domains that bind il-4r |
| EP4019546A1 (en) | 2020-12-23 | 2022-06-29 | Numab Therapeutics AG | Antibody variable domains that bind il-31 |
| EP4019547A1 (en) | 2020-12-23 | 2022-06-29 | Numab Therapeutics AG | Multispecific antibodies having specificity for il-4r and il-31 |
| JP2024504471A (ja) | 2021-02-02 | 2024-01-31 | ヌマブ セラピューティックス アーゲー | Ｒｏｒ１およびｃｄ３に対する特異性を有する多重特異性抗体 |
| WO2022171771A1 (en) | 2021-02-12 | 2022-08-18 | Boehringer Ingelheim International Gmbh | Complement c3 antigen binding proteins |
| EP4183800A1 (en) | 2021-11-19 | 2023-05-24 | Medizinische Hochschule Hannover | Novel sars-cov-2 neutralizing antibodies |
| CR20240265A (es) | 2021-12-22 | 2024-10-16 | Boehringer Ingelheim Int | Anticuerpos anti-c3 y fragmentos de unión al antígeno de estos y sus usos para tratar enfermedades oftálmicas u oculares |
| AU2023265474A1 (en) | 2022-05-06 | 2024-10-31 | Numab Therapeutics AG | Antibody variable domains and antibodies having decreased immunogenicity |
| EP4273162A1 (en) | 2022-05-06 | 2023-11-08 | Numab Therapeutics AG | Antibody variable domains and antibodies having decreased immunogenicity |
| WO2024038095A1 (en) | 2022-08-16 | 2024-02-22 | Iome Bio | NOVEL ANTI-RGMb ANTIBODIES |
| AU2024275787A1 (en) | 2023-05-19 | 2025-11-27 | Numab Therapeutics AG | Antibody variable domains and antibodies having decreased immunogenicity |
| WO2025133389A1 (en) | 2023-12-22 | 2025-06-26 | Numab Therapeutics AG | Antibody binding domains having specificity for lilrb2 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| GB9114948D0 (en) | 1991-07-11 | 1991-08-28 | Pfizer Ltd | Process for preparing sertraline intermediates |
| ES2176484T3 (es) * | 1995-08-18 | 2002-12-01 | Morphosys Ag | Bancos de proteinas/(poli)peptidos. |
| EP1958962A3 (en) | 1997-06-12 | 2013-05-01 | Novartis International Pharmaceutical Ltd. | Artificial antibody polypeptides |
| DE19819846B4 (de) | 1998-05-05 | 2016-11-24 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Multivalente Antikörper-Konstrukte |
| AU2003259718A1 (en) | 2003-08-07 | 2005-03-07 | Epitomics, Inc. | Methods for humanizing rabbit monoclonal antibodies |
| HUE034269T2 (en) * | 2005-12-29 | 2018-02-28 | Janssen Biotech Inc | Human anti-IL-23 antibodies, preparations, methods and applications |
| WO2008004834A1 (en) | 2006-07-06 | 2008-01-10 | Isu Abxis Co., Ltd | Humanized monoclonal antibody highly binding to epidermal growth factor receptor, egf receptor |
| KR20170036814A (ko) | 2007-05-21 | 2017-04-03 | 앨더바이오 홀딩스 엘엘씨 | 신규한 래빗 항체 인간화 방법 및 인간화된 래빗 항체 |
| PL2307458T3 (pl) | 2008-06-25 | 2018-08-31 | Esbatech, An Alcon Biomedical Research Unit Llc | Humanizacja przeciwciał króliczych z zastosowaniem uniwersalnego zrębu przeciwciała |
| US8193235B2 (en) | 2009-06-12 | 2012-06-05 | University Of Kansas | Compositions and methods for establishing and maintaining stem cells in an undifferentiated state |
| WO2014030780A1 (en) * | 2012-08-22 | 2014-02-27 | Mogam Biotechnology Research Institute | Screening and engineering method of super-stable immunoglobulin variable domains and their uses |
| IL243311B (en) * | 2013-06-26 | 2022-07-01 | Numab Therapeutics AG | New frameworks for antibodies |
| EP3060579A1 (en) * | 2013-10-25 | 2016-08-31 | Numab AG | Bispecific constructs and their use in the treatment of various diseases |
| IL293435B1 (en) | 2015-06-15 | 2026-04-01 | Numab Therapeutics AG | Heterodimeric multispecific antibody format |
-
2017
- 2017-09-20 EP EP17192206.5A patent/EP3459968A1/en not_active Withdrawn
-
2018
- 2018-09-19 CA CA3073882A patent/CA3073882A1/en active Pending
- 2018-09-19 AU AU2018335823A patent/AU2018335823B2/en active Active
- 2018-09-19 JP JP2020515647A patent/JP2020535799A/ja active Pending
- 2018-09-19 WO PCT/EP2018/075377 patent/WO2019057787A1/en not_active Ceased
- 2018-09-19 MA MA050159A patent/MA50159A/fr unknown
- 2018-09-19 CN CN201880060278.4A patent/CN111133000A/zh active Pending
- 2018-09-19 EP EP18773174.0A patent/EP3684802A1/en active Pending
- 2018-09-19 US US16/648,588 patent/US11421035B2/en active Active
-
2022
- 2022-08-22 US US17/821,199 patent/US20230242651A1/en not_active Abandoned
-
2023
- 2023-05-31 JP JP2023090016A patent/JP2023115024A/ja active Pending
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