JP2020534873A - バイオマーカー解析のためのデバイス、システム、および方法 - Google Patents

バイオマーカー解析のためのデバイス、システム、および方法 Download PDF

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JP2020534873A
JP2020534873A JP2020538774A JP2020538774A JP2020534873A JP 2020534873 A JP2020534873 A JP 2020534873A JP 2020538774 A JP2020538774 A JP 2020538774A JP 2020538774 A JP2020538774 A JP 2020538774A JP 2020534873 A JP2020534873 A JP 2020534873A
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examples
sample
sequence
minutes
nucleic acid
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JP2020534873A5 (enExample
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デン ブーム，ダーク ヴァン
デン ブーム，ダーク ヴァン
エーリッチ，マティアス
オイス，ポール
チャウバパン，ジム
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ジュノ ダイアグノスティックス，インク．
ジュノ ダイアグノスティックス，インク．
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Publication of JP2020534873A publication Critical patent/JP2020534873A/ja
Publication of JP2020534873A5 publication Critical patent/JP2020534873A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1017—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by filtration, e.g. using filters, frits, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
    • C12Q2565/625—Detection means characterised by use of a special device being a nucleic acid test strip device, e.g. dipsticks, strips, tapes, CD plates

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2020538774A 2017-09-26 2018-09-26 バイオマーカー解析のためのデバイス、システム、および方法 Pending JP2020534873A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762563314P 2017-09-26 2017-09-26
US62/563,314 2017-09-26
US201762609086P 2017-12-21 2017-12-21
US62/609,086 2017-12-21
PCT/US2018/052891 WO2019067567A1 (en) 2017-09-26 2018-09-26 DEVICES, SYSTEMS AND METHODS FOR BIOMARKER ANALYSIS

Publications (2)

Publication Number Publication Date
JP2020534873A true JP2020534873A (ja) 2020-12-03
JP2020534873A5 JP2020534873A5 (enExample) 2021-11-04

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JP2020538774A Pending JP2020534873A (ja) 2017-09-26 2018-09-26 バイオマーカー解析のためのデバイス、システム、および方法

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US (2) US20200263167A1 (enExample)
EP (1) EP3688158A4 (enExample)
JP (1) JP2020534873A (enExample)
KR (1) KR20200083461A (enExample)
CN (1) CN111406107A (enExample)
AU (1) AU2018342449A1 (enExample)
CA (1) CA3076809A1 (enExample)
WO (1) WO2019067567A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024052616A (ja) * 2022-09-30 2024-04-11 デルタ エレクトロニクス インターナショナル （シンガポール） プライベート リミテッド ポータブル核酸検出装置に適した流体カセット

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI833715B (zh) 2017-10-27 2024-03-01 美商奇諾診療公司 用於超低體積液體生物檢體之裝置、系統及方法
EP3517957B1 (en) 2018-01-24 2019-12-18 Midge Medical GmbH Testing assembly and testing device for lateral flow assay
CA3095030A1 (en) 2018-03-30 2019-10-03 Juno Diagnostics, Inc. Deep learning-based methods, devices, and systems for prenatal testing
AU2020354484A1 (en) * 2019-09-23 2022-05-19 Gateway Genomics, Llc Methods, compositions, and kits for determining the sex of a fetus
CA3162239A1 (en) * 2019-11-27 2021-06-03 Juno Diagnostics, Inc. Systems and devices for sample preparation and analyte detection
DE102020109744A1 (de) * 2020-04-07 2021-10-07 Midge Medical Gmbh System und Vorrichtung zum Analysieren einer Probe
US20220042085A1 (en) * 2020-08-07 2022-02-10 Genalyze LLC System and method of nucleic acid amplification for point of collection
EP3967772A1 (en) * 2020-09-14 2022-03-16 Ducrest, Percevent Tools & methods usefool for detection of lactose intolerance and uses thereof
US20240018585A1 (en) * 2020-12-15 2024-01-18 Gateway Genomics, Llc Methods, compositions, and devices for the rapid determination of fetal sex
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US11452474B1 (en) 2021-04-14 2022-09-27 Satio, Inc. Dual lever dermal patch system
US11510602B1 (en) 2021-11-08 2022-11-29 Satio, Inc. Dermal patch for collecting a physiological sample
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
EP4322834A1 (en) * 2021-04-14 2024-02-21 Satio, Inc. Self-contained dermal patch for detection of physiological analytes
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
CA3220201A1 (en) * 2021-06-02 2022-12-08 Jose ZEVALLOS Systems and methods for multimodal analysis of surgical drain fluid using interchangeable and customizable nucleic acid based tests
US12152280B2 (en) 2021-09-20 2024-11-26 Droplet Biosciences, Inc. Drain fluid for diagnostics
WO2023147557A2 (en) * 2022-01-28 2023-08-03 The Johns Hopkins University Bio-engineered enzymes and uses thereof
US12435357B2 (en) 2022-12-22 2025-10-07 Kanso Diagnostics Ltd. Diagnostic device for detecting a target nucleic acid molecule in a biological sample

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008054660A (ja) * 2006-06-29 2008-03-13 Millipore Corp 核酸を単離するためのろ過装置
US20090317817A1 (en) * 2008-03-11 2009-12-24 Sequenom, Inc. Nucleic acid-based tests for prenatal gender determination
JP2011518568A (ja) * 2008-04-28 2011-06-30 バイオタイプ ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｄｎａに基づくプロファイリングアッセイのための物質及び方法
JP2014501555A (ja) * 2010-11-09 2014-01-23 セブンス センス バイオシステムズ，インコーポレーテッド 血液サンプリングのためのシステムおよびインターフェース
JP2015523894A (ja) * 2012-06-20 2015-08-20 ファブプロウス ベスローテン・フェンノートシャップＦａｂｐｕｌｏｕｓ Ｂ．Ｖ． 迅速検査装置および方法
US20160002621A1 (en) * 2014-07-01 2016-01-07 General Electric Company Method, substrate and device for separating nucleic acids
US20160029936A1 (en) * 2014-08-04 2016-02-04 General Electric Company Device for separation and collection of plasma

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1570090A4 (en) * 2002-12-12 2008-01-23 Novartis Vaccines & Diagnostic DEVICE FOR STORING BIOLOGICAL SAMPLES AND PROCESS FOR DETECTING POSSIBLE CONTAMINATION OF BIOLOGICAL SAMPLES
EP1635700B1 (en) * 2003-06-13 2016-03-09 Sanofi-Aventis Deutschland GmbH Apparatus for a point of care device
FR2923151B1 (fr) * 2007-11-02 2010-09-03 Commissariat Energie Atomique Dispositif de prelevement sanguin comportant au moins un filtre .
WO2011053790A2 (en) * 2009-10-30 2011-05-05 Fluidigm Corporation Assay of closely linked targets in fetal diagnosis and coincidence detection assay for genetic analysis
WO2011063324A2 (en) * 2009-11-20 2011-05-26 The General Hospital Corporation Microfluidic systems for isolating microvesicles
EP2516677B1 (en) * 2009-12-23 2014-11-26 Genetic Technologies Limited Methods of enriching and detecting fetal nucleic acids
WO2012174256A2 (en) * 2011-06-17 2012-12-20 The Regents Of The University Of Michigan Dna methylation profiles in cancer
US10262107B1 (en) * 2013-03-15 2019-04-16 Bao Tran Pharmacogenetic drug interaction management system
US9644232B2 (en) * 2013-07-26 2017-05-09 General Electric Company Method and device for collection and amplification of circulating nucleic acids
CA2991918A1 (en) * 2014-07-11 2016-01-14 Advanced Theranostics Inc. Point of care polymerase chain reaction device for disease detection
US10913068B2 (en) * 2015-03-13 2021-02-09 Nanyang Technological University Testing device, microfluidic chip and nucleic acid testing method
TW201703754A (zh) * 2015-05-25 2017-02-01 卡尤迪生物科技（北京）有限公司 用於樣品收集的裝置和方法
ES2912965T3 (es) * 2015-09-09 2022-05-30 Drawbridge Health Inc Dispositivos para la recopilación, estabilización y conservación de muestras
US10508300B2 (en) * 2015-09-18 2019-12-17 Vanadis Diagnostics Probe set for analyzing a DNA sample and method for using the same
WO2017136430A1 (en) * 2016-02-01 2017-08-10 The Board Of Trustees Of The Leland Stanford Junior University Exosome-total-isoloation-chip (exotic) device for isolation of exosome-based biomarkers
US11399755B2 (en) * 2016-08-24 2022-08-02 Becton, Dickinson And Company Device for obtaining a blood sample
PL3336197T3 (pl) * 2016-12-16 2022-08-08 Eurofins Genomics Europe Sequencing GmbH Markery epigenetyczne oraz powiązane sposoby i środki wykrywania i leczenia raka jajnika
CN106978486A (zh) * 2017-03-24 2017-07-25 刘长胜 无细胞dna作为癌症免疫药物疗效评价的分子靶标及其应用

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008054660A (ja) * 2006-06-29 2008-03-13 Millipore Corp 核酸を単離するためのろ過装置
US20090317817A1 (en) * 2008-03-11 2009-12-24 Sequenom, Inc. Nucleic acid-based tests for prenatal gender determination
JP2011518568A (ja) * 2008-04-28 2011-06-30 バイオタイプ ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｄｎａに基づくプロファイリングアッセイのための物質及び方法
JP2014501555A (ja) * 2010-11-09 2014-01-23 セブンス センス バイオシステムズ，インコーポレーテッド 血液サンプリングのためのシステムおよびインターフェース
JP2015523894A (ja) * 2012-06-20 2015-08-20 ファブプロウス ベスローテン・フェンノートシャップＦａｂｐｕｌｏｕｓ Ｂ．Ｖ． 迅速検査装置および方法
US20160002621A1 (en) * 2014-07-01 2016-01-07 General Electric Company Method, substrate and device for separating nucleic acids
US20160029936A1 (en) * 2014-08-04 2016-02-04 General Electric Company Device for separation and collection of plasma

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024052616A (ja) * 2022-09-30 2024-04-11 デルタ エレクトロニクス インターナショナル （シンガポール） プライベート リミテッド ポータブル核酸検出装置に適した流体カセット
JP7764444B2 (ja) 2022-09-30 2025-11-05 デルタ エレクトロニクス インターナショナル （シンガポール） プライベート リミテッド ポータブル核酸検出装置に適した流体カセット

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Publication number Publication date
US20200263167A1 (en) 2020-08-20
CA3076809A1 (en) 2019-04-04
AU2018342449A1 (en) 2020-04-16
KR20200083461A (ko) 2020-07-08
US20220119801A1 (en) 2022-04-21
WO2019067567A1 (en) 2019-04-04
EP3688158A1 (en) 2020-08-05
CN111406107A (zh) 2020-07-10
EP3688158A4 (en) 2021-06-16

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