CA3076809A1 - Devices, systems and methods for biomarker analysis - Google Patents

Devices, systems and methods for biomarker analysis

Info

Publication number
CA3076809A1
CA3076809A1 CA3076809A CA3076809A CA3076809A1 CA 3076809 A1 CA3076809 A1 CA 3076809A1 CA 3076809 A CA3076809 A CA 3076809A CA 3076809 A CA3076809 A CA 3076809A CA 3076809 A1 CA3076809 A1 CA 3076809A1
Authority
CA
Canada
Prior art keywords
instances
sample
sequence
minutes
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3076809A
Other languages
English (en)
French (fr)
Inventor
Dirk Van Den Boom
Mathias Ehrich
Paul OETH
Jim CHAUVAPUN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Juno Diagnostics Inc
Original Assignee
Juno Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Juno Diagnostics Inc filed Critical Juno Diagnostics Inc
Publication of CA3076809A1 publication Critical patent/CA3076809A1/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1017Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by filtration, e.g. using filters, frits, membranes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0681Filter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0825Test strips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60Detection means characterised by use of a special device
    • C12Q2565/625Detection means characterised by use of a special device being a nucleic acid test strip device, e.g. dipsticks, strips, tapes, CD plates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA3076809A 2017-09-26 2018-09-26 Devices, systems and methods for biomarker analysis Pending CA3076809A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762563314P 2017-09-26 2017-09-26
US62/563,314 2017-09-26
US201762609086P 2017-12-21 2017-12-21
US62/609,086 2017-12-21
PCT/US2018/052891 WO2019067567A1 (en) 2017-09-26 2018-09-26 DEVICES, SYSTEMS AND METHODS FOR BIOMARKER ANALYSIS

Publications (1)

Publication Number Publication Date
CA3076809A1 true CA3076809A1 (en) 2019-04-04

Family

ID=65903224

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3076809A Pending CA3076809A1 (en) 2017-09-26 2018-09-26 Devices, systems and methods for biomarker analysis

Country Status (8)

Country Link
US (2) US20200263167A1 (enExample)
EP (1) EP3688158A4 (enExample)
JP (1) JP2020534873A (enExample)
KR (1) KR20200083461A (enExample)
CN (1) CN111406107A (enExample)
AU (1) AU2018342449A1 (enExample)
CA (1) CA3076809A1 (enExample)
WO (1) WO2019067567A1 (enExample)

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TWI833715B (zh) 2017-10-27 2024-03-01 美商奇諾診療公司 用於超低體積液體生物檢體之裝置、系統及方法
EP3517957B1 (en) 2018-01-24 2019-12-18 Midge Medical GmbH Testing assembly and testing device for lateral flow assay
CA3095030A1 (en) 2018-03-30 2019-10-03 Juno Diagnostics, Inc. Deep learning-based methods, devices, and systems for prenatal testing
AU2020354484A1 (en) * 2019-09-23 2022-05-19 Gateway Genomics, Llc Methods, compositions, and kits for determining the sex of a fetus
CA3162239A1 (en) * 2019-11-27 2021-06-03 Juno Diagnostics, Inc. Systems and devices for sample preparation and analyte detection
DE102020109744A1 (de) * 2020-04-07 2021-10-07 Midge Medical Gmbh System und Vorrichtung zum Analysieren einer Probe
US20220042085A1 (en) * 2020-08-07 2022-02-10 Genalyze LLC System and method of nucleic acid amplification for point of collection
EP3967772A1 (en) * 2020-09-14 2022-03-16 Ducrest, Percevent Tools & methods usefool for detection of lactose intolerance and uses thereof
US20240018585A1 (en) * 2020-12-15 2024-01-18 Gateway Genomics, Llc Methods, compositions, and devices for the rapid determination of fetal sex
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US11452474B1 (en) 2021-04-14 2022-09-27 Satio, Inc. Dual lever dermal patch system
US11510602B1 (en) 2021-11-08 2022-11-29 Satio, Inc. Dermal patch for collecting a physiological sample
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
EP4322834A1 (en) * 2021-04-14 2024-02-21 Satio, Inc. Self-contained dermal patch for detection of physiological analytes
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
CA3220201A1 (en) * 2021-06-02 2022-12-08 Jose ZEVALLOS Systems and methods for multimodal analysis of surgical drain fluid using interchangeable and customizable nucleic acid based tests
US12152280B2 (en) 2021-09-20 2024-11-26 Droplet Biosciences, Inc. Drain fluid for diagnostics
WO2023147557A2 (en) * 2022-01-28 2023-08-03 The Johns Hopkins University Bio-engineered enzymes and uses thereof
CN221028439U (zh) * 2022-09-30 2024-05-28 台达电子国际(新加坡)私人有限公司 可携式核酸检测装置
US12435357B2 (en) 2022-12-22 2025-10-07 Kanso Diagnostics Ltd. Diagnostic device for detecting a target nucleic acid molecule in a biological sample

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EP1570090A4 (en) * 2002-12-12 2008-01-23 Novartis Vaccines & Diagnostic DEVICE FOR STORING BIOLOGICAL SAMPLES AND PROCESS FOR DETECTING POSSIBLE CONTAMINATION OF BIOLOGICAL SAMPLES
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US20080113357A1 (en) * 2006-06-29 2008-05-15 Millipore Corporation Filter device for the isolation of a nucleic acid
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WO2011053790A2 (en) * 2009-10-30 2011-05-05 Fluidigm Corporation Assay of closely linked targets in fetal diagnosis and coincidence detection assay for genetic analysis
WO2011063324A2 (en) * 2009-11-20 2011-05-26 The General Hospital Corporation Microfluidic systems for isolating microvesicles
EP2516677B1 (en) * 2009-12-23 2014-11-26 Genetic Technologies Limited Methods of enriching and detecting fetal nucleic acids
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WO2012174256A2 (en) * 2011-06-17 2012-12-20 The Regents Of The University Of Michigan Dna methylation profiles in cancer
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Also Published As

Publication number Publication date
US20200263167A1 (en) 2020-08-20
AU2018342449A1 (en) 2020-04-16
KR20200083461A (ko) 2020-07-08
US20220119801A1 (en) 2022-04-21
WO2019067567A1 (en) 2019-04-04
EP3688158A1 (en) 2020-08-05
CN111406107A (zh) 2020-07-10
EP3688158A4 (en) 2021-06-16
JP2020534873A (ja) 2020-12-03

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