JP2020530777A5 - - Google Patents
Info
- Publication number
- JP2020530777A5 JP2020530777A5 JP2020520429A JP2020520429A JP2020530777A5 JP 2020530777 A5 JP2020530777 A5 JP 2020530777A5 JP 2020520429 A JP2020520429 A JP 2020520429A JP 2020520429 A JP2020520429 A JP 2020520429A JP 2020530777 A5 JP2020530777 A5 JP 2020530777A5
- Authority
- JP
- Japan
- Prior art keywords
- domain
- scfv domain
- quadruspecific
- binding specificity
- percentage homology
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762524557P | 2017-06-25 | 2017-06-25 | |
| US62/524,557 | 2017-06-25 | ||
| PCT/US2018/039156 WO2019005639A2 (en) | 2017-06-25 | 2018-06-22 | MULTISPECIFIC ANTIBODIES AND METHODS OF PREPARATION AND USE THEREOF |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2020530777A JP2020530777A (ja) | 2020-10-29 |
| JPWO2019005639A5 JPWO2019005639A5 (https=) | 2022-02-07 |
| JP2020530777A5 true JP2020530777A5 (https=) | 2022-02-07 |
| JP7399852B2 JP7399852B2 (ja) | 2023-12-18 |
Family
ID=64742644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020520429A Active JP7399852B2 (ja) | 2017-06-25 | 2018-06-22 | 多重特異性抗体とその作製及び使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11787863B2 (https=) |
| EP (1) | EP3645049A4 (https=) |
| JP (1) | JP7399852B2 (https=) |
| KR (2) | KR20250024104A (https=) |
| CN (4) | CN116948035A (https=) |
| AU (2) | AU2018295118B2 (https=) |
| CA (1) | CA3068045A1 (https=) |
| IL (2) | IL313468A (https=) |
| SG (1) | SG11201912864SA (https=) |
| WO (1) | WO2019005639A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20250376531A9 (en) * | 2017-06-25 | 2025-12-11 | Systimmune, Inc. | Anti-4-1bb antibodies and methods of making and using thereof |
| EP3645738A4 (en) * | 2017-06-25 | 2021-08-18 | Systimmune, Inc. | ANTI-PD-L1 ANTIBODIES AND METHOD FOR MANUFACTURING AND USING THEREOF |
| SG11201912865VA (en) * | 2017-06-25 | 2020-01-30 | Systimmune Inc | Multi-specific antibodies and methods of making and using thereof |
| TWI828625B (zh) * | 2017-06-25 | 2024-01-11 | 美商西雅圖免疫公司 | 引導及導航控制蛋白質以及彼之製造及使用方法 |
| US20210008113A1 (en) * | 2018-03-27 | 2021-01-14 | Systimmune, Inc. | Methods of making and using guidance and navigation control proteins |
| PE20220568A1 (es) | 2019-05-21 | 2022-04-20 | Novartis Ag | Moleculas de union a cd19 y usos de las mismas |
| CN114502203B (zh) * | 2019-11-06 | 2024-07-19 | 成都百利多特生物药业有限责任公司 | 制导和导航控制蛋白及其制备和使用方法 |
| EP3988568A1 (en) * | 2020-10-21 | 2022-04-27 | Numab Therapeutics AG | Combination treatment |
| JP2025512953A (ja) * | 2022-04-11 | 2025-04-22 | アストラゼネカ・アクチエボラーグ | Ｔ細胞結合タンパク質 |
| AU2023409023A1 (en) * | 2022-12-20 | 2025-07-31 | Ho'ola Therapeutics Inc. | Combination therapies for the treatment of cancer |
| WO2024160721A1 (en) | 2023-01-30 | 2024-08-08 | Kymab Limited | Antibodies |
| CN116143934B (zh) * | 2023-03-21 | 2023-07-25 | 诺赛联合(北京)生物医学科技有限公司 | 一种干细胞外泌体提取试剂盒及其应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1392359B2 (en) * | 2001-05-11 | 2013-03-13 | Ludwig Institute for Cancer Research Ltd. | Specific binding proteins and uses thereof |
| WO2004029207A2 (en) * | 2002-09-27 | 2004-04-08 | Xencor Inc. | Optimized fc variants and methods for their generation |
| WO2007002223A2 (en) | 2005-06-20 | 2007-01-04 | Medarex, Inc. | Cd19 antibodies and their uses |
| PE20091420A1 (es) | 2007-11-13 | 2009-10-17 | Evec Inc | ANTICUERPOS MONOCLONALES ANTI hGM-CSF |
| US9365644B2 (en) | 2008-04-23 | 2016-06-14 | Epitomics, Inc. | Anti-TNFα antibody |
| PE20120591A1 (es) | 2009-04-02 | 2012-05-23 | Roche Glycart Ag | Anticuerpos multiespecificos que comprenden anticuerpos de longitud completa y fragmentos fab de cadena sencilla |
| TW201100543A (en) * | 2009-05-27 | 2011-01-01 | Hoffmann La Roche | Tri-or tetraspecific antibodies |
| GB201020995D0 (en) * | 2010-12-10 | 2011-01-26 | Bioinvent Int Ab | Biological materials and uses thereof |
| CA2854806A1 (en) * | 2011-11-07 | 2013-05-16 | Medimmune, Llc | Multispecific and multivalent binding proteins and uses thereof |
| PL3489261T3 (pl) * | 2012-08-24 | 2021-08-16 | The Regents Of The University Of California | Przeciwciała i szczepionki do stosowania w leczeniu nowotworów z ekspresją ROR1 i w hamowaniu przerzutu |
| US9732150B2 (en) * | 2013-03-14 | 2017-08-15 | Alderbio Holdings Llc | Therapeutic use of antibodies to HGF |
| EP3013864A1 (en) | 2013-06-26 | 2016-05-04 | Numab AG | Novel antibody frameworks |
| CN105722859B (zh) * | 2013-07-25 | 2021-05-07 | 西托姆克斯治疗公司 | 多特异性抗体、多特异性可活化抗体及其使用方法 |
| JP2016539632A (ja) * | 2013-10-25 | 2016-12-22 | ヌマブ アクチェンゲゼルシャフト | 二重特異性構築物と種々の疾患の治療におけるその使用 |
| CA2940242C (en) | 2014-02-20 | 2026-01-13 | H. Lundbeck A/S | Anti-acth antibodies and use thereof |
| UA117289C2 (uk) * | 2014-04-02 | 2018-07-10 | Ф. Хоффманн-Ля Рош Аг | Мультиспецифічне антитіло |
| WO2016105450A2 (en) | 2014-12-22 | 2016-06-30 | Xencor, Inc. | Trispecific antibodies |
| EP3253790A4 (en) * | 2015-02-06 | 2018-07-25 | University of Maryland, Baltimore | Tetra-specific, octameric binding agents and antibodies against clostridium difficile toxin a and toxin b for treatment of c. difficile infection |
| CN104829733B (zh) * | 2015-05-25 | 2018-06-05 | 广州百暨基因科技有限公司 | 抗原结合单元稳定的嵌合抗原受体及制备方法与应用 |
| JP6932700B2 (ja) * | 2015-09-15 | 2021-09-08 | アムジエン・インコーポレーテツド | ４価の二重特異性抗原結合タンパク質及び４価の四重特異性抗原結合タンパク質、ならびにそれらの使用 |
| SG11201912865VA (en) * | 2017-06-25 | 2020-01-30 | Systimmune Inc | Multi-specific antibodies and methods of making and using thereof |
| TWI828625B (zh) * | 2017-06-25 | 2024-01-11 | 美商西雅圖免疫公司 | 引導及導航控制蛋白質以及彼之製造及使用方法 |
| US20210008113A1 (en) * | 2018-03-27 | 2021-01-14 | Systimmune, Inc. | Methods of making and using guidance and navigation control proteins |
-
2018
- 2018-06-22 CN CN202310922275.XA patent/CN116948035A/zh active Pending
- 2018-06-22 JP JP2020520429A patent/JP7399852B2/ja active Active
- 2018-06-22 CN CN202310141321.2A patent/CN116199785A/zh active Pending
- 2018-06-22 SG SG11201912864SA patent/SG11201912864SA/en unknown
- 2018-06-22 CA CA3068045A patent/CA3068045A1/en active Pending
- 2018-06-22 CN CN201880039401.4A patent/CN110831973B/zh active Active
- 2018-06-22 KR KR1020257003259A patent/KR20250024104A/ko active Pending
- 2018-06-22 EP EP18825293.6A patent/EP3645049A4/en active Pending
- 2018-06-22 WO PCT/US2018/039156 patent/WO2019005639A2/en not_active Ceased
- 2018-06-22 AU AU2018295118A patent/AU2018295118B2/en active Active
- 2018-06-22 CN CN202310141062.3A patent/CN116041530A/zh active Pending
- 2018-06-22 KR KR1020207002328A patent/KR102763369B1/ko active Active
- 2018-06-22 IL IL313468A patent/IL313468A/en unknown
- 2018-06-22 US US16/615,122 patent/US11787863B2/en active Active
- 2018-06-22 IL IL271257A patent/IL271257B2/en unknown
-
2025
- 2025-06-27 AU AU2025204860A patent/AU2025204860A1/en active Pending
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