JP2020528743A5 - - Google Patents
Info
- Publication number
- JP2020528743A5 JP2020528743A5 JP2019571042A JP2019571042A JP2020528743A5 JP 2020528743 A5 JP2020528743 A5 JP 2020528743A5 JP 2019571042 A JP2019571042 A JP 2019571042A JP 2019571042 A JP2019571042 A JP 2019571042A JP 2020528743 A5 JP2020528743 A5 JP 2020528743A5
- Authority
- JP
- Japan
- Prior art keywords
- modified protein
- asparaginase
- amino acid
- seq
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023030460A JP7770352B2 (ja) | 2017-06-21 | 2023-02-28 | 修飾されたｌ－アスパラギナーゼ |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762523061P | 2017-06-21 | 2017-06-21 | |
| EP17177237.9 | 2017-06-21 | ||
| US62/523,061 | 2017-06-21 | ||
| EP17177237.9A EP3418383A1 (en) | 2017-06-21 | 2017-06-21 | Modified l-asparaginase |
| US15/671,086 | 2017-08-07 | ||
| US15/671,086 US10174302B1 (en) | 2017-06-21 | 2017-08-07 | Modified L-asparaginase |
| PCT/EP2018/066647 WO2018234492A1 (en) | 2017-06-21 | 2018-06-21 | L-ASPARAGINASE MODIFIED |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023030460A Division JP7770352B2 (ja) | 2017-06-21 | 2023-02-28 | 修飾されたｌ－アスパラギナーゼ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020528743A JP2020528743A (ja) | 2020-10-01 |
| JP2020528743A5 true JP2020528743A5 (enExample) | 2025-05-08 |
| JP7808424B2 JP7808424B2 (ja) | 2026-01-29 |
Family
ID=64737515
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019571042A Active JP7808424B2 (ja) | 2017-06-21 | 2018-06-21 | 修飾されたｌ－アスパラギナーゼ |
| JP2023030460A Active JP7770352B2 (ja) | 2017-06-21 | 2023-02-28 | 修飾されたｌ－アスパラギナーゼ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023030460A Active JP7770352B2 (ja) | 2017-06-21 | 2023-02-28 | 修飾されたｌ－アスパラギナーゼ |
Country Status (15)
| Country | Link |
|---|---|
| EP (2) | EP3642340B1 (enExample) |
| JP (2) | JP7808424B2 (enExample) |
| KR (1) | KR102727396B1 (enExample) |
| CN (1) | CN111315878B (enExample) |
| AU (1) | AU2018287145B2 (enExample) |
| BR (1) | BR112019027479A2 (enExample) |
| CA (1) | CA3068100A1 (enExample) |
| DK (1) | DK3642340T3 (enExample) |
| ES (1) | ES2979314T3 (enExample) |
| FI (1) | FI3642340T3 (enExample) |
| IL (1) | IL271504B2 (enExample) |
| MX (2) | MX2019015502A (enExample) |
| SA (2) | SA522433360B1 (enExample) |
| SG (1) | SG11201912625QA (enExample) |
| WO (1) | WO2018234492A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7065772B2 (ja) | 2015-12-22 | 2022-05-12 | エクスエル‐プロテイン ゲーエムベーハー | 低反復性ヌクレオチド配列を有する、プロリンおよびアラニン残基が豊富な反復性アミノ酸配列をコードする核酸 |
| US12478604B1 (en) | 2016-07-22 | 2025-11-25 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
| US12186296B1 (en) | 2016-07-22 | 2025-01-07 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| ES2979314T3 (es) * | 2017-06-21 | 2024-09-25 | Jazz Pharmaceuticals Ireland Ltd | L-asparaginasa modificada |
| EP3713595A1 (en) * | 2017-11-22 | 2020-09-30 | Merz Pharma GmbH & Co. KGaA | Novel recombinant botulinum toxin with increased duration of effect |
| BR112021013766A2 (pt) | 2019-03-01 | 2021-09-21 | Flamel Ireland Limited | Composições de gama-hidroxibutirato com farmacocinética melhorada no estado alimentado |
| CA3156066A1 (en) * | 2019-10-25 | 2021-04-29 | Mi Rim Choi | Recombinant l-asparaginase |
| KR20230125179A (ko) * | 2020-12-23 | 2023-08-29 | 재즈 파마슈티칼즈 아일랜드 리미티드 | 전하-차폐 융합 단백질의 정제 방법 |
| WO2022211829A1 (en) | 2021-03-30 | 2022-10-06 | Jazz Pharmaceuticals Ireland Ltd. | Dosing of recombinant l-asparaginase |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
| US20260007728A1 (en) | 2022-07-14 | 2026-01-08 | Jazz Pharmaceuticals Ireland Ltd. | Combination therapies involving l-asparaginase |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| EP0206448B1 (en) | 1985-06-19 | 1990-11-14 | Ajinomoto Co., Inc. | Hemoglobin combined with a poly(alkylene oxide) |
| GB8519753D0 (en) * | 1985-08-06 | 1985-09-11 | Health Lab Service Board | Production of 1-asparaginase |
| GB9017002D0 (en) * | 1990-08-02 | 1990-09-19 | Health Lab Service Board | Improved method for the purification of erwina l-asparaginase |
| WO2007103290A2 (en) | 2006-03-03 | 2007-09-13 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Materials and methods directed to asparagine synthetase and asparaginase therapies |
| EP2851424B1 (en) * | 2007-03-09 | 2016-09-21 | Novozymes A/S | Thermostable asparaginases |
| US8563521B2 (en) | 2007-06-21 | 2013-10-22 | Technische Universitat Munchen | Biological active proteins having increased in vivo and/or in vitro stability |
| WO2011003633A1 (en) * | 2009-07-06 | 2011-01-13 | Alize Pharma Ii | Pegylated l-asparaginase |
| DK2571510T3 (en) * | 2010-05-21 | 2018-11-19 | Xl Protein Gmbh | BIOSYNTHETIC PROLIN / ALANIN-RANDOM COIL POLYPEPTIDES AND THEIR APPLICATIONS |
| CN104302408B (zh) | 2012-02-27 | 2016-12-14 | 阿穆尼克斯运营公司 | Xten缀合组合物和制造其的方法 |
| ES2979314T3 (es) | 2017-06-21 | 2024-09-25 | Jazz Pharmaceuticals Ireland Ltd | L-asparaginasa modificada |
-
2018
- 2018-06-21 ES ES18731853T patent/ES2979314T3/es active Active
- 2018-06-21 EP EP18731853.0A patent/EP3642340B1/en active Active
- 2018-06-21 CA CA3068100A patent/CA3068100A1/en active Pending
- 2018-06-21 MX MX2019015502A patent/MX2019015502A/es unknown
- 2018-06-21 SG SG11201912625QA patent/SG11201912625QA/en unknown
- 2018-06-21 DK DK18731853.0T patent/DK3642340T3/da active
- 2018-06-21 CN CN201880054251.4A patent/CN111315878B/zh active Active
- 2018-06-21 FI FIEP18731853.0T patent/FI3642340T3/fi active
- 2018-06-21 KR KR1020207002029A patent/KR102727396B1/ko active Active
- 2018-06-21 EP EP22204187.3A patent/EP4180525A1/en active Pending
- 2018-06-21 JP JP2019571042A patent/JP7808424B2/ja active Active
- 2018-06-21 AU AU2018287145A patent/AU2018287145B2/en active Active
- 2018-06-21 BR BR112019027479-0A patent/BR112019027479A2/pt unknown
- 2018-06-21 WO PCT/EP2018/066647 patent/WO2018234492A1/en not_active Ceased
- 2018-06-21 IL IL271504A patent/IL271504B2/en unknown
-
2019
- 2019-12-18 MX MX2024015050A patent/MX2024015050A/es unknown
- 2019-12-21 SA SA522433360A patent/SA522433360B1/ar unknown
- 2019-12-21 SA SA519410870A patent/SA519410870B1/ar unknown
-
2023
- 2023-02-28 JP JP2023030460A patent/JP7770352B2/ja active Active
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